Neoplasms, Muscle Tissue: Clinical Trials

412 completed, 111 recruiting, 107 unknown, 91 terminated. 253 Phase 2, 183 Not applicable, 167 Phase 1, 102 Phase 3, 46 Phase 4.

By phase and status

Phase	Trials	Status
Phase 2	253	Completed 131, Recruiting 35, Terminated 30, Active not recruiting 26, Unknown 20, Withdrawn 6, Not yet recruiting 4, Suspended 1
Not applicable	183	Completed 85, Unknown 37, Recruiting 17, Terminated 15, Not yet recruiting 14, Active not recruiting 7, Withdrawn 7, Enrolling by invitation 1
Phase 1	167	Completed 82, Recruiting 34, Terminated 19, Active not recruiting 13, Unknown 7, Withdrawn 7, Not yet recruiting 3, Enrolling by invitation 1, Suspended 1
Phase 3	102	Completed 57, Terminated 19, Recruiting 9, Unknown 6, Active not recruiting 5, Withdrawn 5, Not yet recruiting 1
Phase 4	46	Completed 20, Unknown 12, Terminated 7, Recruiting 3, Not yet recruiting 2, Withdrawn 2
Early Phase 1	12	Active not recruiting 4, Completed 4, Terminated 2, Not yet recruiting 1, Recruiting 1

Follow Neoplasms, Muscle Tissue: new trials by email Literature Review of Neoplasms, Muscle Tissue trials Research Report on Neoplasms, Muscle Tissue

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
A Phase 1/2 Study of CBX-12 in Children, Adolescents, or Young Adults With Solid Tumors That Have Come Back After Treatment or Are Difficult to Treat Archive Sample Retrieval, Biospecimen Collection, pH Low Insertion Peptide-exatecan Conjugate CBX-12 - Recurrent Childhood Ewing Sarcoma, Recurrent Childhood Malignant Solid Neoplasm	Phase 1 / Phase 2	Not yet recruiting	Children's Oncology Group	79	2027-05-07	2026-09-22
Tumor-Lymph Node Mapping ICG (Indocyanine Green) - Pediatric Solid Tumors, Rhabdomyosarcoma		Not yet recruiting	University of Rochester	10	2026-12-13	2026-08-26
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma Doxorubicin - Sarcoma	Phase 2	Recruiting	University of Colorado, Denver	20	2026-12-01	2026-02-05
A Phase 1b, Open-Label Study Of REC-617, A Selective CDK7 Inhibitor, In Patients With Metastatic Or Unresectable RB1-Negative Leiomyosarcoma After Prior Systemic Therapy REC617 - Phase 1b, Open Label	Phase 1	Recruiting	M.D. Anderson Cancer Center	15	2026-10-19	2026-07-31
Stellate Ganglion Block and Dexmedetomidine for Postoperative Sleep in Women Undergoing Laparoscopic Gynecologic Surgery DEX 0.2 μg/kg/h., SGB, 0.9% Sodium Chloride (Placebo) - Uterine Fibroids (Leiomyoma), Adenomyosis of Uterus	Not applicable	Recruiting	Catherin Zhang	100	2026-10-01	2026-10-06
LapBox® Manual Containment System LapBox Manual Containment System, Standard of Care Specimen Bag - Surgery	Not applicable	Not yet recruiting	University of Wisconsin, Madison	24	2026-10-01	2026-10-01
Vaginal Sildenafil for Primary Dysmenorrhea Sildenafil citrate vaginal suppository - Dysmenorrhea, Menstrual Pain	Phase 1	Not yet recruiting	Kevin Hellman	10	2026-10-01	2026-09-25
A Prospective Validation Study of Radiomics in the Differential Diagnosis of Uterine Leiomyoma and Uterine Sarcoma No intervention (observational study) - Uterine Fibroid, Uterine Sarcoma		Not yet recruiting	Tongji Hospital	500	2026-09-30	2026-10-08
Artificial Intelligence Into Ultrasound Diagnostics in Reproductive Medicine Endometriosis, Adenomyosis of Uterus		Recruiting	Semmelweis University	1600	2026-09-01	2026-09-18
Prospective Perioperative Clinical Registry for Women Undergoing Benign Gynecological Surgery Standard Surgical Procedures for Benign Gynecological Conditions - Benign Gynecological Disease, Uterine Fibroids		Not yet recruiting	IRCCS San Raffaele	6000	2026-09-01	2026-08-19
GCAR1, a Chimeric Antigen Receptor (CAR) T-CELL Therapy for Relapsed/Refractory GPNMB-Expressing Solid Tumours Fludarabine, Cyclophosphamide, GCAR1 - Alveolar Soft Part Sarcoma, Renal Cell Carcinoma	Phase 1	Recruiting	Canadian Cancer Trials Group	30	2026-08-30	2026-10-16
FATIMA Trial: EGCG and Vitamin D3 for Prevention of Fibroid Recurrence Vitamin D and Green Tea, Placebo - Uterine Fibroids (Leiomyoma)	Phase 2	Recruiting	Sheikh Shakhbout Medical City	240	2026-08-22	2026-06-16
my.naviGATE: A Guide to After-Treatment Effects for Adolescents and Young Adults my.naviGATE Digital Tool - Sarcoma, Osteosarcoma	Not applicable	Not yet recruiting	Dana-Farber Cancer Institute	143	2026-08-20	2026-04-08
Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma Proton Therapy (Adaptive) - Pediatric Solid Tumors, Rhabdomyosarcoma	Not applicable	Recruiting	St. Jude Children's Research Hospital	100	2026-08-20	2026-08-21
Terlipressin vs Placebo to Reduce Bleeding in Fibroid Surgery terlipressin (vasoconstrictor), Placebo - Uterine Fibroids (Leiomyoma), Uterine Myoma	Not applicable	Not yet recruiting	Sevil Cankaya	80	2026-08-01	2026-08-05
Safety and Efficacy of Microwave Ablation Alone Versus Microwave Ablation Combined With Chemical Ablation in the Treatment of Uterine Fibroids: A Prospective, Multicenter Study Microwave ablation combined with chemical ablation, Microwave ablation - Uterine Fibroids (UF), Microwave Ablation	Not applicable	Not yet recruiting	Peking University Aerospace Center Hospital	248	2026-08-01	2026-08-10
Impact of Educational Videos on Pre-operative Anxiety educational video - Endometriosis, Fibroids	Not applicable	Enrolling by invitation	UConn Health	60	2026-07-17	2026-08-03
A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS) Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Rhabdomyosarcoma	Phase 3	Recruiting	Children's Oncology Group	342	2026-07-14	2026-08-25
Study Comparing Two Serums With Intense Pulsed Light for the Treatment of Moderate to Severe Photodamage and Crepiness on the Forearms Right Arm treated with Active Re-Q Pro-Longevity Serum and Intense Pulsed Light Therapy, Left Arm treated with vehicle serum and Intense Pulsed Light Therapy - Photodamaged Skin	Phase 2 / Phase 3	Not yet recruiting	Goldman, Butterwick, Fitzpatrick and Groff	20	2026-07-10	2026-07-07
Cyclobenzaprine for Postoperative Pain in Minimally Invasive Hysterectomy Cyclobenzaprine - Minimally Invasive Surgical Procedures, Abnormal Uterine Bleeding, Unspecified	Phase 4	Not yet recruiting	Christiana Care Health Services	36	2026-07-01	2026-06-24

Showing 20 of 855. Sign in to see all of them.

Narrower conditions

Leiomyoma (422)  ·  Rhabdomyosarcoma (230)  ·  Sarcoma (208)  ·  Leiomyosarcoma (157)  ·  Sarcoma, Ewing (114)  ·  Osteosarcoma (108)  ·  Neuroblastoma (94)  ·  Liposarcoma (92)  ·  Sarcoma, Synovial (75)  ·  Histiocytoma, Malignant Fibrous (63)  ·  Menorrhagia (60)  ·  Wilms Tumor (60)  ·  Neurofibrosarcoma (57)  ·  Sarcoma, Alveolar Soft Part (51)  ·  Myoma (50)

Broader conditions

Neoplasms by Histologic Type (853)  ·  Neoplasms, Connective and Soft Tissue (851)  ·  Neoplasms (819)  ·  Neoplasms, Connective Tissue (281)  ·  Urogenital Diseases (267)  ·  Female Urogenital Diseases and Pregnancy Complications (258)  ·  Female Urogenital Diseases (255)  ·  Myosarcoma (245)  ·  Genital Diseases (196)  ·  Pathological Conditions, Signs and Symptoms (196)  ·  Sarcoma (192)  ·  Genital Diseases, Female (180)  ·  Neoplasms, Nerve Tissue (175)  ·  Pathologic Processes (174)

Interventions

Doxorubicin (36)  ·  Cyclophosphamide (29)  ·  Vincristine (26)  ·  Radiotherapy (25)  ·  Ifosfamide (21)  ·  Irinotecan (21)  ·  Temozolomide (21)  ·  Gemcitabine (20)  ·  ulipristal acetate (20)  ·  Uterine Myomectomy (19)  ·  Filgrastim (18)  ·  telapristone acetate (18)  ·  Dactinomycin (16)  ·  Specimen Handling (15)  ·  Trabectedin (14)

Sponsors

National Cancer Institute (NCI) (56)  ·  Children's Oncology Group (18)  ·  Repros Therapeutics Inc. (18)  ·  St. Jude Children's Research Hospital (18)  ·  European Organisation for Research and Treatment of Cancer - EORTC (16)  ·  Memorial Sloan Kettering Cancer Center (16)  ·  Bayer (14)  ·  Baylor College of Medicine (10)  ·  InSightec (10)  ·  Abbott (9)  ·  AbbVie (8)  ·  M.D. Anderson Cancer Center (8)  ·  University Magna Graecia (8)  ·  Gynesonics (7)  ·  Northwestern University (7)

Countries

United States (437)  ·  Canada (79)  ·  France (66)  ·  Italy (60)  ·  United Kingdom (58)  ·  China (54)  ·  Germany (50)  ·  Spain (45)  ·  Belgium (40)  ·  Netherlands (39)  ·  Australia (38)  ·  Poland (33)  ·  Puerto Rico (29)  ·  Egypt (22)  ·  Switzerland (22)

Top investigators

Anna Chan (6)  ·  AeRang Kim, MD, PhD (4)  ·  Fulvio Zullo, MD,PhD (4)  ·  Robert Maki, MD, PhD (4)  ·  Vanessa Jacoby, MD (4)  ·  Andre van As, MD, PhD (3)  ·  Crystal L Mackall, M.D. (3)  ·  David Steffin, MD (3)

Results publications

PMID 31401903, PMID 36357960, PMID 38603649, PMID 31971678, PMID 32827353, PMID 33596357, PMID 34878624, PMID 37477173, PMID 37863160, PMID 18774375, PMID 23188490, PMID 24444087, PMID 24630081, PMID 28385194, PMID 28947860, PMID 30262660, PMID 30617491, PMID 30865281, PMID 30969201, PMID 31444600, PMID 31575518, PMID 33544889, PMID 33650259, PMID 34272196, PMID 34553161, PMID 34582715, PMID 35415708, PMID 35675604, PMID 36116480, PMID 36470211, PMID 37183454, PMID 37666383, PMID 39381651, PMID 39466126, PMID 40077973, PMID 40326221, PMID 40543832, PMID 42573020, PMID 10797354, PMID 11705489, PMID 11814511, PMID 12038814, PMID 12065559, PMID 12423842, PMID 12501064, PMID 12520530, PMID 12524074, PMID 12528778, PMID 12957454, PMID 15010069

NIH funding

U10CA180886 (21), U10CA098543 (12), 2016 (7), 2017 (4), 2018 (4), P30CA008748 (4), 2014 (3), P30CA033572 (3), P50CA272170 (3), UM1CA186709 (3), 2009 (2), 2015 (2), 2023 (2), N01CM62206 (2), P30CA060553 (2)