13 completed, 2 terminated, 1 withdrawn. 6 Phase 2, 4 Not applicable, 4 Phase 1, 4 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 5, Terminated 1 |
| Not applicable | 4 | Completed 3, Withdrawn 1 |
| Phase 1 | 4 | Completed 2, Terminated 2 |
| Phase 3 | 4 | Completed 4 |
| Phase 4 | 1 | Completed 1 |
Follow indolepropanol phosphate: new trials by email Literature Review of indolepropanol phosphate trials Research Report on indolepropanol phosphate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Individualized Pneumoperitoneum Pressure in Colorectal Laparoscopic Surgery Versus Standard Therapy (IPPCollapse-II) IPP in colorectal laparoscopic surgery, SPP in colorectal laparoscopic surgery - Colorectal Surgery, Laparoscopy | Phase 4 | Completed | Instituto de Investigacion Sanitaria La Fe | 204 | 2017-01-25 | 2020-04-15 |
| Whole-Body Radiation Therapy, Systemic Chemotherapy, and High-Dose Chemotherapy Followed By Stem Cell Rescue in Treating Patients With Poor-Risk Ewing Sarcoma etoposide, ifosfamide, intensity-modulated radiation therapy - Adult Supratentorial Primitive Neuroectodermal Tumor (PNET), Ewing Sarcoma of Bone | Not applicable | Withdrawn | City of Hope Medical Center | 2013-07-01 | 2015-01-09 | |
| Combination Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin Lymphoma bleomycin sulfate, doxorubicin hydrochloride, liposomal vincristine sulfate - Childhood Nodular Lymphocyte Predominant Hodgkin Lymphoma, Stage III Childhood Hodgkin Lymphoma | Phase 3 | Completed | Children's Oncology Group | 166 | 2009-12-07 | 2022-04-28 |
| Effect of Ile-Pro-Pro (IPP) on Endothelial Function in Patients With Coronary Artery Disease IPP, Placebo - Coronary Artery Disease | Not applicable | Completed | Boston University | 54 | 2009-07-01 | 2012-05-25 |
| Two Regimens of Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed Localized Ewing Sarcoma Family of Tumors radiation therapy, therapeutic conventional surgery, etoposide - Ewing Sarcoma of Bone, Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Not applicable | Completed | Children's Oncology Group | 35 | 2008-03-01 | 2014-09-25 |
| Vorinostat, Rituximab, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Lymphoma or Previously Untreated T-Cell Non-Hodgkin Lymphoma or Mantle Cell Lymphoma vorinostat, rituximab, ifosfamide - Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma | Phase 1 / Phase 2 | Completed | University of Washington | 29 | 2007-12-01 | 2017-05-25 |
| Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma doxorubicin hydrochloride, clinical observation, therapeutic conventional surgery - Adult Alveolar Soft-part Sarcoma, Adult Angiosarcoma | Phase 3 | Completed | Children's Oncology Group | 588 | 2007-02-05 | 2022-04-28 |
| The Intermittent Pneumoperitoneum Scheme of Work Breaks in Complex Laparoscopic Surgery IPP - Stress Physiology, Staff Work Load | Not applicable | Completed | Hannover Medical School | 56 | 2007-01-01 | 2009-11-06 |
| Ifosfamide, Carboplatin, Etoposide, and SGN-30 in Treating Young Patients With Recurrent Anaplastic Large Cell Lymphoma monoclonal antibody SGN-30, therapeutic hydrocortisone, ifosfamide - Anaplastic Large Cell Lymphoma, Recurrent Childhood Anaplastic Large Cell Lymphoma | Phase 1 / Phase 2 | Terminated | National Cancer Institute (NCI) | 5 | 2007-01-01 | 2018-03-14 |
| Bortezomib, Ifosfamide, and Vinorelbine Tartrate in Treating Young Patients With Hodgkin's Lymphoma That is Recurrent or Did Not Respond to Previous Therapy ifosfamide, bortezomib, vinorelbine tartrate - Adult Lymphocyte Depletion Hodgkin Lymphoma, Adult Lymphocyte Predominant Hodgkin Lymphoma | Phase 2 | Completed | National Cancer Institute (NCI) | 26 | 2007-01-01 | 2021-03-24 |
| Combination Chemotherapy Followed by Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin's Lymphoma radiation therapy, doxorubicin hydrochloride, vincristine sulfate - Childhood Favorable Prognosis Hodgkin Lymphoma, Childhood Lymphocyte Depletion Hodgkin Lymphoma | Phase 3 | Completed | Children's Oncology Group | 287 | 2006-02-01 | 2021-03-30 |
| Ifosfamide With or Without O(6)-Benzylguanine in Treating Patients With Unresectable, Metastatic Solid Tumors ifosfamide, O6-benzylguanine - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Terminated | National Cancer Institute (NCI) | 32 | 2004-06-01 | 2013-01-24 |
| Oblimersen, Rituximab and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Aggressive Non-Hodgkin's Lymphoma oblimersen sodium, rituximab, ifosfamide - Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Grade 3 Follicular Lymphoma | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 25 | 2004-05-01 | 2013-01-24 |
| Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Children With Acute Lymphoblastic Leukemia filgrastim, asparaginase, cyclophosphamide - Childhood Acute Lymphoblastic Leukemia in Remission, Recurrent Childhood Acute Lymphoblastic Leukemia | Phase 3 | Completed | National Cancer Institute (NCI) | 220 | 2002-10-01 | 2014-02-27 |
| Comparison of Chemotherapy Regimens in Treating Children With Relapsed or Progressive Rhabdomyosarcoma vincristine sulfate, irinotecan hydrochloride, cyclophosphamide - Alveolar Childhood Rhabdomyosarcoma, Embryonal Childhood Rhabdomyosarcoma | Phase 2 | Completed | National Cancer Institute (NCI) | 150 | 2001-11-01 | 2013-01-17 |
| Chemotherapy With or Without Trastuzumab in Treating Patients With Metastatic Osteosarcoma doxorubicin hydrochloride, cisplatin, methotrexate - Metastatic Osteosarcoma | Phase 2 | Completed | National Cancer Institute (NCI) | 80 | 2001-07-01 | 2013-02-04 |
Hodgkin Disease (4) · Lymphoma, Follicular (2) · Lymphoma, Large B-Cell, Diffuse (2) · Lymphoma, Large-Cell, Anaplastic (2) · Lymphoma, Mantle-Cell (2) · Neuroectodermal Tumors, Primitive, Peripheral (2) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (2) · Anuria (1) · Burkitt Lymphoma (1) · Chondrosarcoma, Extraskeletal Myxoid (1) · Coronary Artery Disease (1) · Dermatofibrosarcoma (1) · Fibrosarcoma (1) · Fractures, Stress (1) · Hemangiopericytoma, Malignant (1)
National Cancer Institute (NCI) (7) · Children's Oncology Group (4) · Boston University (1) · City of Hope Medical Center (1) · Hannover Medical School (1) · Instituto de Investigacion Sanitaria La Fe (1) · University of Washington (1)
United States (14) · Australia (2) · Canada (2) · Puerto Rico (2) · Germany (1) · Israel (1) · New Zealand (1) · Spain (1)
Sonali Smith (2) · Anna Pawlowska (1) · Benno M Ure, PhD (1) · David Ebb (1) · Frank Keller, MD (1) · John Sandlund (1) · Joseph A Vita, MD (1) · Kara Kelly, MD (1) · Kirk Schultz (1) · Leo Mascarenhas, MD MS (1) · Lihua Budde (1) · Philip Breitfeld (1) · Sheri Spunt, MD (1) · Terzah Horton (1)
PMID 37505794, PMID 25833390, PMID 28391003, PMID 30944044, PMID 30954717, PMID 31786124, PMID 32154021, PMID 32506481, PMID 33242441, PMID 33548339, PMID 34623899, PMID 35763667, PMID 36566574, PMID 38757485, PMID 39969278, PMID 41386267
U10CA098543 (9), N01CM62201 (1), U01CA069852 (1)