206 unknown. 206 Phase 2, 41 Phase 1, 26 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 206 | Unknown 206 |
| Phase 1 | 41 | Unknown 41 |
| Phase 3 | 26 | Unknown 26 |
Follow Neurodegenerative Diseases: new trials by email Literature Review of Neurodegenerative Diseases trials Research Report on Neurodegenerative Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MRG-001 in Patients With Amyotrophic Lateral Sclerosis MRG-001 - Amyotrophic Lateral Sclerosis, Lou Gehrig Disease | Phase 2 | Unknown | MedRegen LLC | 10 | 2025-07-01 | 2024-08-23 |
| Cilostazol in Parkinson's Disease Cilostazol, Placebo, Standard treatment - Parkinson's Disease | Phase 2 | Unknown | Ain Shams University | 50 | 2024-10-01 | 2024-09-25 |
| Node-Sparing Short-Course Radiation With CAPOX and Sintilimab for MSS Locally Advanced Colon Cancer: A Randomized, Prospective, Multicenter Study Node-Sparing Short-Course Radiotherapy Combined with CAPOX and Sintilimab, CAPOX Chemotherapy - Microsatellite Stable (MSS) Colon Cancer, Locally Advanced Colon Cancer | Phase 2 | Unknown | Sir Run Run Shaw Hospital | 140 | 2024-10-01 | 2024-09-19 |
| Effect of Salbutamol on Walking Capacity in Ambulatory ALS Patients Salbutamol, Placebo - Walking Capacity, Amyotrophic Lateral Sclerosis | Phase 2 | Unknown | Assistance Publique - Hôpitaux de Paris | 36 | 2024-09-01 | 2024-04-12 |
| Estimates of the Short-term Efficacy of Talineuren (TLN) and Placebo in Patients With Parkinson Disease Talineuren, Placebo - Parkinson Disease | Phase 2 | Unknown | InnoMedica Schweiz AG | 40 | 2024-08-01 | 2024-05-29 |
| Efficacy, Safety and Response Predictors of Astragalus Membranaceus on the Improvement of Cognitive Function in Mild-to-Moderate Alzheimer's Disease 10g Astragalus, Routine treatment, 20g Astragalus - Alzheimer's Disease | Phase 2 | Unknown | Fujian Medical University Union Hospital | 66 | 2024-05-01 | 2024-07-03 |
| CVL237 Tablets for APDS/PASLI CVL237 tablets, CVL237 placebo tablets - PI3K and P110delta Hyperactivation Syndrome | Phase 2 / Phase 3 | Unknown | Convalife (Shanghai) Co., Ltd. | 35 | 2024-03-30 | 2024-03-05 |
| Efficacy, Safety and Response Predictors of Adjuvant Astragalus for Cognition in Orthostatic Hypotension Routine treatment, add-on low dose Astragalus, add-on high dose Astragalus - Orthostatic Hypotension, Alzheimer Disease | Phase 2 | Unknown | Fujian Medical University Union Hospital | 66 | 2024-02-20 | 2024-01-05 |
| Tirzepatide Monotherapy in Patients With Wolfram Syndrome Type 1 Tirzepatide - Wolfram Syndrome | Phase 2 | Unknown | Ospedale San Raffaele | 10 | 2024-01-01 | 2024-02-22 |
| Safety and Efficacy of AR1005 in Patients with Lewy Body Disease AR1005, Placebo, Rivastigmine 3 mg - Lewy Body Dementia | Phase 2 | Unknown | Yonsei University | 60 | 2024-01-01 | 2024-10-02 |
| High-Dose Ambroxol in GBA1-Related Parkinson Ambroxol Hydrochloride - Parkinson Disease, GBA Gene Mutation | Phase 1 / Phase 2 | Unknown | Agyany Pharma LTD | 40 | 2023-10-24 | 2024-02-08 |
| Randomized Clinical Trial of Donepezil for the Treatment of Mild Cognitive Impairment in Parkinson's Disease Donepezil Hydrochloride, Placebo - Parkinson Disease, Mild Cognitive Impairment | Phase 2 | Unknown | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 120 | 2023-10-01 | 2023-09-28 |
| Hereditary Sensory Neuropathy Serine Trial L-serine, Placebo - Hereditary Sensory Neuropathy Type I | Phase 2 | Unknown | University College, London | 50 | 2023-08-21 | 2023-11-02 |
| Toxicity and Efficacy Evaluation of Topical Minoxidil in Acne Vulgaris topical minoxidil in Acne Vulgaris - Acne Vulgaris | Phase 1 / Phase 2 | Unknown | Chang Gung Memorial Hospital | 26 | 2023-07-11 | 2023-11-03 |
| A Double-blind Randomised, Placebo-controlled Clinical Trial to Test Ambroxol Treatment in ALS Ambroxol, Placebo - Amyotrophic Lateral Sclerosis | Phase 2 | Unknown | The Florey Institute of Neuroscience and Mental Health | 50 | 2023-06-13 | 2023-09-07 |
| Study of APH-1105 in Patients With Mild to Moderate Alzheimer's Disease APH-1105, Placebo - Dementia, Alzheimer Disease 1 | Phase 2 | Unknown | Aphios | 60 | 2023-06-01 | 2021-07-27 |
| GRoningen Early-PD Ambroxol Treatment Ambroxol Hydrochloride, Placebo - Parkinson, Parkinson Disease | Phase 2 / Phase 3 | Unknown | University Medical Center Groningen | 80 | 2023-05-01 | 2023-05-10 |
| Tdap and Biomarkers of Alzheimer's Disease tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine - Alzheimer Disease, Late Onset | Phase 1 / Phase 2 | Unknown | Mindful Diagnostics and Therapeutics, LLC | 50 | 2023-05-01 | 2022-08-25 |
| Protecting Alzheimer Caregivers Using Technology Through Staying Sharp Staying Sharp intervention - Mild Cognitive Impairment, Dementia Alzheimers | Phase 1 / Phase 2 | Unknown | Oregon Health and Science University | 138 | 2023-04-30 | 2023-02-09 |
| Effect of Folic Acid in Levodopa Treated Parkinson's Disease Patients Folic Acid Tablet, Placebo - Parkinson Disease | Phase 2 | Unknown | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 60 | 2023-04-16 | 2023-09-26 |
Showing 20 of 206. Sign in to see all of them.
Parkinson Disease (71) · Alzheimer Disease (61) · Amyotrophic Lateral Sclerosis (28) · Cognitive Dysfunction (15) · Dementia (10) · Supranuclear Palsy, Progressive (6) · Frontotemporal Dementia (5) · Hereditary Sensory and Autonomic Neuropathies (4) · Nervous System Diseases (4) · Tuberous Sclerosis (4) · Anxiety Disorders (3) · Bulbo-Spinal Atrophy, X-Linked (3) · Dementia, Vascular (3) · Huntington Disease (3)
Nervous System Diseases (202) · Central Nervous System Diseases (182) · Brain Diseases (149) · Basal Ganglia Diseases (83) · Mental Disorders (83) · Movement Disorders (82) · Neurocognitive Disorders (76) · Synucleinopathies (74) · Parkinsonian Disorders (73) · Tauopathies (67) · Dementia (63) · Neuromuscular Diseases (43) · Metabolic Diseases (40) · Nutritional and Metabolic Diseases (40)
Donepezil (9) · Sodium Chloride (4) · Cell- and Tissue-Based Therapy (3) · Droxidopa (3) · Levetiracetam (3) · Levodopa (3) · Albuterol (2) · Ambroxol (2) · Botulinum Toxins, Type A (2) · Dronabinol (2) · Edaravone (2) · Everolimus (2) · Exenatide (2) · Interleukin-2 (2) · Melatonin (2)
Chang Gung Memorial Hospital (9) · Peking University Third Hospital (4) · University College, London (4) · University of Calgary (4) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (3) · Tel-Aviv Sourasky Medical Center (3) · University Medical Center Groningen (3) · Assistance Publique - Hôpitaux de Paris (2) · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh (2) · Cardiff University (2) · Centre Hospitalier Universitaire de Nice (2) · Collaborative Medicinal Development Pty Limited (2) · Dongzhimen Hospital, Beijing (2) · Erasmus Medical Center (2) · Fujian Medical University Union Hospital (2)
United States (39) · China (37) · Canada (14) · France (13) · South Korea (11) · Taiwan (10) · United Kingdom (9) · Italy (8) · Netherlands (7) · Australia (6) · Brazil (6) · Israel (5) · Germany (4) · Iran (3) · Poland (3)
Dongsheng Fan (3) · Abraham Lieberman, MD (2) · Dominic Rowe, MD (2) · Veronica Bruno, MD, MPH (2) · Abdallah Awidi, MD (1) · Agessandro Abrahao, MD, MSc (1) · Alessandra Lugaresi, MD, PhD (1) · Alexander Kaplan (1) · Alfonso Fasano, MD, PhD (1) · Ali R Ahmadi, MD PhD (1) · Alissa Ash, Dr. (1) · Amir Ali Hamidieh, MD (1) · Angelo E Schenone, MD (1) · Ari Zimran, MD (1)
PMID 12465055, PMID 1463007, PMID 15496622, PMID 16214880, PMID 1674640, PMID 18441370, PMID 18441371, PMID 18442107, PMID 18546344, PMID 18591063, PMID 18774912, PMID 19077238, PMID 1928099, PMID 19387333, PMID 19524477, PMID 19740486, PMID 20962287, PMID 21525172, PMID 21525519, PMID 21791473, PMID 21921019, PMID 21953990, PMID 22612072, PMID 22644094, PMID 23063736, PMID 23151076, PMID 23728174, PMID 23934921, PMID 24217017, PMID 24396955, PMID 24438512, PMID 24778283, PMID 24794816, PMID 24820540, PMID 24910427, PMID 25093483, PMID 25324884, PMID 25382161, PMID 25649017, PMID 25669730, PMID 25796592, PMID 25888232, PMID 25950380, PMID 26474316, PMID 26480849, PMID 26606867, PMID 26709292, PMID 26892229, PMID 27160012, PMID 27386292
2018 (2), 2009 (1), 2014 (1), 2016 (1), 2017 (1), P30AG024978 (1), R01AG025502 (1), R01AG043398 (1), R44AG061981 (1), R44AG071388 (1)