13 completed, 9 recruiting, 4 terminated, 3 enrolling by invitation. 7 Not applicable, 4 Phase 2, 2 Phase 1, 2 Phase 3.
Follow Neurodegenerative Disease: new trials by email Literature Review of Neurodegenerative Disease trials Research Report on Neurodegenerative Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cognition and Affective Research in China Neurodegenerative Disease, Dementia | Not yet recruiting | Xuanwu Hospital, Beijing | 3000 | 2026-10-01 | 2026-09-22 | |
| DIV-AD BARCELONA: Alzheimer's Blood-Based Biomakers for a Diverse Community Alzheimer Disease, Cognitive Dysfunction, Cognitive Disorder | Not yet recruiting | Barcelonabeta Brain Research Center, Pasqual Maragall Foundation | 250 | 2026-04-27 | 2026-04-13 | |
| Human Observatory Study Multi-Domain Ecological and Clinical Data Linkage - Aging, Mortality | Recruiting | Longevity Metrics, Inc. | 1000000 | 2026-04-25 | 2026-09-08 | |
| Deciphering the Effect of Moderate Wine Consumption on Healthy Aging Through Postprandial Extracellular Vesicles. White Wine, Red Wine, Water - Atherosclerosis Cardiovascular Disease, Obesity | Not applicable | Recruiting | University of Seville | 8 | 2025-11-01 | 2026-01-23 |
| [18F]NIDF PET Imaging in Tau-related Diseases Neurodegenerative Disease, Alzheimer s Disease | Recruiting | Tianjin Medical University | 20 | 2025-11-01 | 2026-09-08 | |
| ADAI - Home Care in Intelligent Environments Clinical Care Ecosystem for the Management of Home Digital Therapies Through the Use of Assistive Robots and Clinical Predictive Systems Based on Artificial Intelligence Systems CLINICAL INVESTIGATION WITH A MEDICAL DEVICE MARKED CE - Neurodegenerative Disease, Artificial Intelligence (AI) | Not applicable | Completed | IRCCS Centro Neurolesi Bonino Pulejo | 23 | 2025-09-22 | 2026-05-05 |
| Mindfulness Walking Intervention to Enhance Resilience (iWalk) iWalk Program - Neurodegenerative Disease, EEG | Not applicable | Recruiting | University of Illinois at Urbana-Champaign | 90 | 2025-06-01 | 2025-12-16 |
| VR-based Physical Activity and Reminiscence Therapy aPAVRCT - Dementia, Neurodegenerative Disease | Phase 1 / Phase 2 | Not yet recruiting | Hong Kong University of Science and Technology | 100 | 2025-05-19 | 2025-05-22 |
| Understanding How Gut and Brain Barriers Are Linked to Inflammation in Obesity Obesity (Disorder), Systemic Inflammation Markers | Completed | University Hospital, Gentofte, Copenhagen | 50 | 2025-04-01 | 2026-02-18 | |
| Dyadic Mindfulness for People With Parkinson's Disease and Their Caregivers Dyadic mindfulness - Mindfulness, Caregivers | Not applicable | Recruiting | The University of Hong Kong | 200 | 2025-02-11 | 2026-06-01 |
| Parkinson and the Males Body Composition Neurodegenerative Disease | Completed | University of Oviedo | 15 | 2024-12-01 | 2025-05-18 | |
| A Phase 3 Study of NTLA-2001 in ATTRv-PN nexiguran ziclumeran, Normal Saline as Placebo - Neuromuscular Disease, Neuromuscular Diseases (NMD) | Phase 3 | Recruiting | Intellia Therapeutics | 60 | 2024-11-22 | 2026-04-16 |
| Investigating the Neural Signature of Freezing of Gait in Parkinson's Disease Parkinson Disease, Freezing of Gait | Enrolling by invitation | KU Leuven | 28 | 2024-11-04 | 2025-02-24 | |
| Exploring the Olfactory Mucosa, Blood and Urine for the Identification of Early Biomarkers of Parkinson's Disease, Atypical Parkinsonisms and Neurocognitive Disorders Due to Lewy Body Disease Parkinson Disease, MSA - Multiple System Atrophy | Active not recruiting | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | 180 | 2023-10-03 | 2026-08-28 | |
| Clinical Cohort of Memory Disorders Neurodegenerative Disease, Mild Cognitive Impairmen | Recruiting | Yonsei University | 1550 | 2020-09-10 | 2026-10-19 | |
| Effects of Combined Aerobic and Cognitive Training in a Simultaneous or Sequential Paradigm on Cognition and Brain Functional Activity in Patients with AMCI Simultaneous aerobic and cognitive training (SIM), Sequential aerobic and cognitive training (SEQ) - Mild Cognitive Impairment (MCI), AMCI - Amnestic Mild Cognitive Impairment | Not applicable | Active not recruiting | IRCCS San Raffaele | 55 | 2019-04-05 | 2025-01-10 |
| Tracking and Predicting How Brain Damage Spreads in Neurodegenerative Diseases 3 Tesla MRI without contrast medium, Blood sample for genetic analysis, Cerebrospinal fluid sampling (CSF) - Neurodegenerative Disease, Behavioral Variant Frontotemporal Dementia (bvFTD) | Not applicable | Enrolling by invitation | IRCCS San Raffaele | 645 | 2017-06-01 | 2026-05-05 |
| A Biomarker-chip Assay in Preserved Red Blood Cells for the Diagnosis of Alzheimer's Disease Alzheimer's Disease (AD), Neurodegenerative Disease | Completed | Amoneta Diagnostics SAS | 150 | 2017-03-23 | 2025-12-29 | |
| PET Tau - Neurodegenerative Disease Imaging 18F-AV-1451 - Neurodegenerative Disease | Phase 2 / Phase 3 | Recruiting | University of Pennsylvania | 300 | 2016-08-23 | 2026-10-16 |
| Amyotrophic Lateral Sclerosis and the Innate Immune System Amyotrophic Lateral Sclerosis, Neurodegenerative Disease | Unknown | Copenhagen University Hospital, Rigshospitalet | 375 | 2016-06-01 | 2017-10-06 |
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Neurodegenerative Diseases (36) · Amyotrophic Lateral Sclerosis (13) · Movement Disorders (12) · Motor Neuron Disease (11) · Dementia (8) · Parkinson Disease (7) · Alzheimer Disease (6) · Cognitive Dysfunction (6) · Metabolic Diseases (2) · Metabolic Syndrome (2) · Nerve Degeneration (2) · Nervous System Diseases (2) · Neuromuscular Diseases (2) · Obesity (2) · Plaque, Amyloid (2)
Nervous System Diseases (34) · Central Nervous System Diseases (26) · Nutritional and Metabolic Diseases (19) · Metabolic Diseases (16) · Proteostasis Deficiencies (15) · Brain Diseases (14) · Mental Disorders (14) · TDP-43 Proteinopathies (14) · Neurocognitive Disorders (13) · Spinal Cord Diseases (13) · Neuromuscular Diseases (12) · Pathological Conditions, Signs and Symptoms (12) · Basal Ganglia Diseases (7) · Cognition Disorders (7) · Parkinsonian Disorders (7)
7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole (1) · Blood Specimen Collection (1) · Cognitive Training (1) · Deferiprone (1) · Dextromethorphan (1) · Genetic Testing (1) · NTLA-2001 (1) · Physical Examination (1) · Saline Solution (1) · Solutions (1) · Water (1)
Drexel University College of Medicine (9) · IRCCS San Raffaele (2) · National Institute of Neurological Disorders and Stroke (NINDS) (2) · Amoneta Diagnostics SAS (1) · Barcelonabeta Brain Research Center, Pasqual Maragall Foundation (1) · Copenhagen University Hospital, Rigshospitalet (1) · Ente Ospedaliero Ospedali Galliera (1) · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta (1) · Hanyang University Seoul Hospital (1) · Hong Kong University of Science and Technology (1) · IRCCS Centro Neurolesi Bonino Pulejo (1) · Intellia Therapeutics (1) · KU Leuven (1) · Longevity Metrics, Inc. (1) · Massachusetts General Hospital (1)
United States (16) · Italy (5) · Spain (3) · China (2) · Denmark (2) · South Korea (2) · Argentina (1) · Belgium (1) · Brazil (1) · Hong Kong (1) · Mexico (1) · Singapore (1) · Switzerland (1) · Taiwan (1) · Thailand (1)
Terry Heiman-Patterson, MD (5) · Anne-Marie Wills, MD (1) · David Irwin, MD (1) · Fabio Moda, PHD (1) · Genalynne C Mooneyham, M.D. (1) · Gian Luca Forni, MD (1) · Karsten Skovgaard Olsen, Dr.med. (1) · Michael Weiner, MD (1) · Moran Gilat, PhD (1) · Peter Garred, Prof., MD (1)
PMID 21791473, PMID 23868881, PMID 24274034, PMID 25894712, PMID 28120370, PMID 31142272, PMID 31657503, PMID 32759248
2017 (1)