378 completed, 50 unknown, 30 recruiting, 21 terminated. 321 Not applicable, 60 Phase 2, 57 Phase 1, 45 Phase 4, 40 Phase 3.
Follow Water: new trials by email Literature Review of Water trials Research Report on Water
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Increased Water Intake on Hormonal Response, Hydration Status, and Physical Function in Low-drinking Older Adults Water - Dehydrated, Water-Electrolyte Imbalance, Malnutrition, Dehydration (Physiology) | Not applicable | Not yet recruiting | Polytechnic University of Santarém | 38 | 2026-11-01 | 2026-10-23 |
| The Impact of Perioperative Lidocaine Infusions on Enhanced Recovery After Non-Cardiac Surgery Lidocaine HCl 0.8% in D5W, Dextrose 5% in water - Pain, Post Operative Analgesia | Phase 4 | Not yet recruiting | Vanderbilt University Medical Center | 2290 | 2026-10-31 | 2026-10-15 |
| Rapid Rehydration for Severe Hypernatremia Intravenous Dextrose 5% solution - Hypernatremia | Phase 2 | Recruiting | Columbia University | 80 | 2026-10-22 | 2026-10-27 |
| Effectiveness of Pre-Procedural CPC and Zinc Mouthwash in Reducing Dental Aerosols 0.09% CPC + Zinc Lactate Mouthwash, 0.2% Chlorhexidine Mouthwash, Water - Bacterial Contamination | Phase 4 | Not yet recruiting | Colgate Palmolive | 60 | 2026-10-08 | 2026-10-19 |
| The Effect of Water Temperature on Heart Rate Variability and Cognition water - Mental Acuity | Not applicable | Not yet recruiting | Arizona State University | 30 | 2026-07-13 | 2026-06-17 |
| Effect of SugarLock® Peanut Skin Extract on Postprandial Blood Glucose Control Peanut skin extract, White kidney bean extract, Water - Blood Sugar (Glucose) Control, Postprandial Glucose | Not applicable | Recruiting | TCI Co., Ltd. | 30 | 2026-07-09 | 2026-07-15 |
| Occupational Exposure to Whole Body Vibration Among U.S. Military Veterans: Acute and Chronic Contributions to Musculoskeletal Disorders and Spine-Area Pain Water - Spine Health, Spine Injuries and Disorders | Not applicable | Not yet recruiting | Milwaukee VA Medical Center | 112 | 2026-07-01 | 2026-01-26 |
| The Influence of Water Intake on Snack Intake in Children Snack with water, Snack without water - Eating Behaviors | Not applicable | Not yet recruiting | Cornell University | 50 | 2026-06-29 | 2026-07-02 |
| The Role of Carbohydrate Blends and Electrolytes on Physical and Mental Performance During Cycling in the Heat Water (Placebo), Carbohydrate Milk Permeate sports drink, 6% Sports drink - Hydration, Dehydration (Physiology) | Not applicable | Not yet recruiting | Arizona State University | 14 | 2026-06-22 | 2026-06-22 |
| Electrolyte Beverage Combined With Polyethylene Glycol for Colonoscopy Bowel Preparation PEG With Water, PEG With Low-dose Electrolyte Beverage, PEG With Medium-dose Electrolyte Beverage - Colonoscopy, Bowel Preparation Solutions | Not applicable | Recruiting | Nanfang Hospital, Southern Medical University | 405 | 2026-05-18 | 2026-05-27 |
| Racecadotril for Organ Injury in Sepsis Patients Racecadotril, Water (Placebo) - Sepsis | Phase 1 / Phase 2 | Enrolling by invitation | Zhujiang Hospital | 44 | 2026-05-06 | 2026-05-28 |
| Injection of IP-001 Into Thermally Ablated Hepatic Tumors in Patients With Colorectal Liver Metastases 1.0% IP-001 for Injection, a 10 mg/mL solution of IP-001 in water, 1.0% IP-001 for Injection, a 1 mg/mL solution of IP-001 in water., Microwave (thermal) tumor ablation - Colorectal Cancer (CRC), Colon Cancer Liver Metastases | Phase 2 / Phase 3 | Not yet recruiting | Immunophotonics, Inc. | 717 | 2026-05-01 | 2026-01-07 |
| Effect of Lemon Juice and Apple Cider Vinegar on Postprandial Blood Glucose and Satiety in Healthy Individuals Control (Water + White Bread), Lemon Juice 50 g, Lemon Juice 100 g - Satiety, Postprandial Glycemia | Not applicable | Recruiting | Alanya Alaaddin Keykubat University | 15 | 2026-05-01 | 2026-05-04 |
| Postpartum 8-aminoquinoline Breast Milk Study Daily primaquine (0.5 mg/kg per day) for 14 days given with food food and water, Daily primaquine 1 mg/kg per day for 7 days given with food and water, Single-dose tafenoquine given with food and water to prevent gastrointestinal discomfort - Drug Pharmacokinetics in Healthy Volunteers | Phase 2 / Phase 3 | Not yet recruiting | Curtin University | 60 | 2026-04-01 | 2026-03-18 |
| The Influence of Water Intake on Food Intake at Meals Varying in Moisture No water, Water, Low Moisture - Eating Behaviors | Not applicable | Recruiting | Cornell University | 60 | 2026-03-15 | 2026-04-23 |
| Beverage Hydration Index of Different Solutions Hydramin hydration solution, Carbohydrate and Electrolyte hydration solution, Water - Hydration | Not applicable | Completed | University of Memphis | 30 | 2026-02-23 | 2026-08-14 |
| Absorption of Iron From Stabilized Lactoferrin: A Study in Women With Iron Deficiency FeSO4 + meal-matrix, FeSO4 + native LF + meal-matrix, FeSO4 + NaCas-LF + meal-matrix - Iron Deficiency (Without Anemia) | Not applicable | Recruiting | Nicole Stoffel | 45 | 2026-02-17 | 2026-02-12 |
| The Impact of a Caffeinated Sports Drink on Performance carbohydrate electrolyte drink, no-sugar electrolyte drink, Caffeinated Carbohydrate and electrolyte drink - Dehydration, Dehydration Related to Exercise | Not applicable | Completed | Arizona State University | 26 | 2025-12-12 | 2026-01-27 |
| The Impact of Valerian and Chamomile on Children's Anxiety in the Dental Clinic Valerian extract, Chamomile extract, Water (Placebo) - Anxiety, Dental | Not applicable | Completed | Damascus University | 78 | 2025-12-01 | 2026-09-01 |
| Oral vs. Intravenous Hydration to Prevent Contrast-Associated Acute Kidney Injury in the ED Water, %0,9 NaCl - Contrast-Associated Acute Kidney Injury, Contrast-induced Nephropathy | Not applicable | Recruiting | Gaziosmanpasa Research and Education Hospital | 198 | 2025-11-07 | 2026-03-09 |
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Obesity (32) · Insulin Resistance (16) · Pain (16) · Diabetes Mellitus, Type 2 (15) · Dehydration (14) · Motor Activity (13) · Diabetes Mellitus (12) · Inflammation (11) · Anxiety Disorders (8) · COVID-19 (8) · Feeding Behavior (6) · Hypertension (6) · Cardiovascular Diseases (5) · Colorectal Neoplasms (5) · Dental Caries (5)
University Hospital, Basel, Switzerland (9) · University of Toronto (7) · AstraZeneca (5) · Tranzyme, Inc. (5) · University of Reading (5) · Vivozon, Inc. (5) · Arizona State University (4) · GlaxoSmithKline (4) · Hadassah Medical Organization (4) · Parc de Salut Mar (4) · Seoul National University Hospital (4) · Société des Produits Nestlé (SPN) (4) · Toronto Metropolitan University (4) · Unilever R&D (4) · Universitaire Ziekenhuizen KU Leuven (4)
United States (150) · Canada (42) · United Kingdom (36) · China (26) · Switzerland (20) · Turkey (Türkiye) (20) · Italy (16) · Denmark (14) · Taiwan (13) · Brazil (12) · Israel (12) · South Korea (12) · Spain (12) · France (11) · Belgium (9)
Rainard Fuhr, Dr. med. (3) · Richard Bloomer, PhD (3) · Seonjun Bae, MD, PhD (3) · Yanglin Pan, MD (3) · Youlin Yang, M.D. (3) · Andrea R Josse, PhD (2) · Anne Christin Meyer-Gerspach, PD, PhD (2) · Christoph Beglinger, MD (2) · Edward CM Lo, BDS, PhD (2) · G. Harvey Anderson, Ph.D. (2)
PMID 19403473, PMID 20354090, PMID 23739196, PMID 29806553, PMID 36819512, PMID 1017769, PMID 10343249, PMID 10409601, PMID 10933646, PMID 10988126, PMID 11112885, PMID 11145118, PMID 11156645, PMID 11172481, PMID 11225528, PMID 11238483, PMID 11505791, PMID 11673599, PMID 11717205, PMID 11719303, PMID 11857360, PMID 12054359, PMID 12145777, PMID 12170403, PMID 12399273, PMID 12450897, PMID 12915639, PMID 1305308, PMID 1406301, PMID 14522731, PMID 1460185, PMID 14767878, PMID 1479177, PMID 15044883, PMID 15172894, PMID 15269196, PMID 15316186, PMID 15331548, PMID 15738894, PMID 15818423, PMID 1588830, PMID 15888773, PMID 16015276, PMID 16219100, PMID 16266222, PMID 16332934, PMID 16423633, PMID 16490989, PMID 16648017, PMID 16785338
2017 (2), 2025 (2), 1UM1HL116885-01 (1), 2015 (1), 2018 (1), P01DK068055 (1), P01HL056693 (1), P30DK020579 (1), R01AG071151 (1), R01CI000373 (1), R01DK102359 (1), R01DK112317 (1), R01DK117028 (1), R01DK138155 (1), R01DK149765 (1)