316 completed. 316 Phase 3, 73 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 316 | Completed 316 |
| Phase 2 | 73 | Completed 73 |
Follow Mouth Diseases: new trials by email Literature Review of Mouth Diseases trials Research Report on Mouth Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Investigate Toothpaste on Antibacterial Effects in the Different Regions of the Mouth stannous fluoride toothpaste, 0.76% Sodium Monofluorophosphate (Na MFP) toothpaste - Plaque, Gingivitis | Phase 3 | Completed | Colgate Palmolive | 95 | 2026-05-18 | 2026-09-24 |
| Efficacy of a Stannous Fluoride Toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen in Reducing Established Dental Plaque and Gingivitis. 0.454%Stannous fluoride toothpaste, 0.075% Cetylpyridinium Chloride (CPC) and 0.28% zinc lactatmouthwashe, 0.76% Sodium Monofluorophosphate (Na MFP) toothpaste - Plaque | Phase 3 | Completed | Colgate Palmolive | 134 | 2026-01-26 | 2026-05-22 |
| Comparative Evaluation of Oxygen-enriched and Chlorohexidine Mouthwashes as an Adjunct to Non-surgical Periodontal Therapy and Its Efficacy on Gingival Inflammation, Plaque Scores and Patient-reported Outcomes CHX mouthwash, Oxygen-enriched mouthwash - Periodontal Disease, Periodontal Diseases Inflammation | Phase 3 | Completed | Cairo University | 72 | 2025-12-01 | 2026-10-06 |
| Investigation of Clinical Efficacy of a New Mouthwash on Reducing Dental Plaque and Helping Prevent Gum Problems as Compared to a Control Mouthwash cetylpyridinium chloride (CPC), zinc lactate and sodium fluoride Mouthwash, sodium fluoride Mouthwash - Gingivitis, Plaque, Dental | Phase 3 | Completed | Colgate Palmolive | 80 | 2025-12-01 | 2026-05-26 |
| The Efficacy of a Battery Toothbrush in the Reduction of Established Plaque and Gingivitis Total Active Prevention Fresh Toothpaste + Colgate Total Active Prevention Battery Toothbrush, Colgate Great Regular + Total Active Prevention Battery Toothbrush, Colgate Great Regular + standard reference flat trim toothpaste - Plaque, Gingivitis | Phase 3 | Completed | Colgate Palmolive | 130 | 2025-10-14 | 2026-10-29 |
| Clinical Investigation of PerioGard (Test) Regimen PeriGuard regimen, Colgate Dental Cream regimen - Gingivitis | Phase 3 | Completed | Colgate Palmolive | 80 | 2025-08-18 | 2026-03-18 |
| Evaluation of Liquorice Nanogel Versus Diode Laser as an Adjunctive Treatment for Patients With Periodontitis Stage Ⅲ. Liquorice Nanogel, diode laser - Diode Laser Therapy, Periodontal Disease | Phase 3 | Completed | Al-Azhar University | 27 | 2025-07-01 | 2026-09-29 |
| Evaluation of the Effect of a Toothpaste Containing 0.3% Chlorhexidine in Subjects With Established Dental Plaque and Gingivitis Chlorhexidine toothpaste, Toothbrush, Placebo toothpaste without chlorhexidine and AmCl - Gingivitis, Gingivitis and Periodontal Diseases | Phase 3 | Completed | Colgate Palmolive | 80 | 2025-03-24 | 2025-08-06 |
| Hyaluronic Acid Mouthwash as Adjunct Hyaluoric acid mouthwash, Chlorhexidine 0,12% - Gingivitis; Chronic | Phase 3 | Completed | Cairo University | 16 | 2025-02-01 | 2026-01-26 |
| Clinical Efficacy of the Combined Effect of Oral Irrigator and Chemicals (0.075% CPC) oral irrigator, Cetylpyridinium Chloride (CPC) - Dental Plaque, Dental Plaque Induced Gingivitis | Phase 3 | Completed | Colgate Palmolive | 30 | 2024-09-30 | 2024-12-13 |
| Clinical Research Study to Assess the Efficacy of Two Brushing Regimens Test Regimen, Control Regimen - Dental Plaque, Gingivitis | Phase 3 | Completed | Colgate Palmolive | 90 | 2024-09-23 | 2026-02-06 |
| Comparative Study to Evaluate the Efficacy of an Alcohol-free Mouthwash Regimen With CPC+Zn, Flossing and Brushing, and an Alcohol-based Mouthwash Regimen With Essential Oils in Reducing Plaque and Gingivitis. Mouthwash CPC+Zn+F, Essential oils mouthwash, Dental floss - Gingival Bleeding, Plaque Induced Gingival Disease | Phase 3 | Completed | Colgate Palmolive | 120 | 2024-09-17 | 2025-04-14 |
| Comparative Study of CPC+Zn Mouthwash, Dental Floss, and Essential Oils Mouthwash on Plaque and Gingivitis Reduction Mouthwash CPC+Zn+F, Essential oils mouthrinse, Dental floss - Gingival Bleeding, Plaque Induced Gingival Disease | Phase 3 | Completed | Colgate Palmolive | 120 | 2024-09-16 | 2025-04-14 |
| Comparison Study of SIBP's MMR Vaccine Versus GSK MMR Vaccine in Children Aged 9-11 Months SIBP MMR Vaccine, GSK MMR Vaccine (PRIORIX), Yellow Fever Vaccine (Stamaril) - Measles-Mumps-Rubella | Phase 3 | Completed | Shanghai Institute Of Biological Products | 1200 | 2024-06-28 | 2026-01-08 |
| Clinical and Radiographic Evaluation of The Effect of Acetal Resin Versus PEEK on Supporting Structure of Abutment Teeth Acetal resin - Periodontal Diseases | Phase 3 | Completed | Al-Azhar University | 50 | 2024-05-15 | 2025-03-18 |
| Study of Abobotulinum Toxin Versus Neubotulinum Toxin Injection For Hemifacial Spasm in Thai Patients Injection botulinum toxin A ( Dysport 100 unit or Neuronox 33.33 unit) - Hemifacial Spasm | Phase 3 | Completed | Department of Medical Services Ministry of Public Health of Thailand | 107 | 2024-05-01 | 2026-08-17 |
| Shaping the Indications for Periodontal Adjunctive Antibiotics in Dental Practice Amoxicillin, Metronidazole, Placebo - Periodontitis, Periodontal Diseases | Phase 3 | Completed | Rutgers, The State University of New Jersey | 236 | 2024-04-25 | 2026-04-14 |
| The Clinical of Stannous Fluoride Toothpaste and a Newly Designed Toothbrush Compared to Colgate Cavity Protection Toothpaste and a Regular Toothbrush in Reducing Plaque and Gingivitis. Stannous fluoride toothpaste, Colgate Cavity Protection Toothpaste - Plaque, Gingivitis | Phase 3 | Completed | Colgate Palmolive | 95 | 2024-04-22 | 2026-03-19 |
| Investigation of Colgate Dual Zinc Toothpaste as Compared to Colgate Cavity Protection Toothpaste in Controlling Plaque and Gingivitis zinc containing toothpaste, MFP Fluoride toothpaste - Plaque, Dental, Gingivitis | Phase 3 | Completed | Colgate Palmolive | 86 | 2024-04-15 | 2026-03-19 |
| Anti-gingivitis Mouthrinse Amine/zinc lactate/fluoride system, negative control - Gingivitis | Phase 3 | Completed | Colgate Palmolive | 90 | 2024-03-06 | 2025-05-21 |
Showing 20 of 316. Sign in to see all of them.
Chronic Periodontitis (39) · Gingivitis (35) · Mumps (34) · Measles (32) · Rubella (31) · Periodontitis (29) · Periodontal Diseases (27) · Stomatitis (27) · Chickenpox (25) · Head and Neck Neoplasms (23) · Mucositis (15) · Dental Plaque (14) · Mouth Neoplasms (14) · Herpes Labialis (13) · Squamous Cell Carcinoma of Head and Neck (13)
Stomatognathic Diseases (316) · Periodontal Diseases (117) · Infections (93) · Pathological Conditions, Signs and Symptoms (79) · Salivary Gland Diseases (65) · Pathologic Processes (57) · Virus Diseases (51) · Neoplasms by Site (42) · Chronic Disease (41) · DNA Virus Infections (41) · Disease Attributes (41) · Herpesviridae Infections (41) · Skin and Connective Tissue Diseases (41) · Gingival Diseases (40)
measles, mumps, rubella, varicella vaccine (15) · Triclosan (12) · Fluorides (11) · Measles-Mumps-Rubella Vaccine (8) · hydrated silica gel-based toothpaste (8) · Metronidazole (6) · Tooth Exfoliation (6) · Acyclovir (5) · Amoxicillin (5) · Cetylpyridinium (5) · Fibroblast Growth Factor 7 (5) · Metformin (5) · Radiotherapy (5) · Chickenpox Vaccine (4) · Hepatitis A Vaccines (4)
Colgate Palmolive (29) · Government Dental College and Research Institute, Bangalore (24) · GlaxoSmithKline (13) · Merck Sharp & Dohme LLC (13) · Cairo University (7) · Dr. D. Y. Patil Dental College & Hospital (6) · Amgen (5) · Islamic Azad University, Sanandaj (5) · Al-Azhar University (4) · Dow University of Health Sciences (4) · Novartis Pharmaceuticals (4) · OraPharma (4) · Sanofi Pasteur, a Sanofi Company (4) · Universidade Estadual Paulista Júlio de Mesquita Filho (4) · University of Sao Paulo (4)
United States (82) · India (29) · Brazil (24) · France (23) · Egypt (19) · Germany (18) · Canada (15) · China (15) · Spain (13) · Italy (11) · Puerto Rico (8) · South Korea (8) · Japan (7) · United Kingdom (7) · Israel (6)
Cassiano K Rosing, PhD (2) · Chikara Ieda (2) · Jean Bourhis, PhD (2) · Jingchen Ma (2) · Luigi Montesani, DDS (2) · Magda Feres, Professor (2) · Mauro Santamaria, Professor (2) · Yanfang Ren, DDS (2)
PMID 12897619, PMID 18573992, PMID 23959319, PMID 10423050, PMID 10477976, PMID 12419687, PMID 12533152, PMID 14718694, PMID 15016256, PMID 15161841, PMID 15287367, PMID 15316186, PMID 15602019, PMID 16161031, PMID 16225582, PMID 16391299, PMID 16415901, PMID 16452343, PMID 16567978, PMID 16804432, PMID 16862549, PMID 17079762, PMID 17293228, PMID 17502347, PMID 17580258, PMID 17668979, PMID 17716312, PMID 17716313, PMID 18413833, PMID 18454655, PMID 18596969, PMID 18672990, PMID 18696746, PMID 18754720, PMID 19125084, PMID 19273678, PMID 19366435, PMID 19563331, PMID 19711612, PMID 19733615, PMID 19854614, PMID 20141576, PMID 20151804, PMID 20348487, PMID 20354090, PMID 20406930, PMID 20831669, PMID 20851499, PMID 20937388, PMID 21091369
2018 (2), 2008 (1), 2009 (1), 2014 (1), 2017 (1), 2023 (1), 4UH3DE031129-02 (1), P01CA106451 (1), P30CA008748 (1), P30CA068485 (1), R01CA107080 (1), R01DE012215 (1), R01DE012872 (1), R21CA098792 (1), R21DE023046 (1)