36 completed, 9 unknown, 5 terminated, 4 recruiting. 61 Phase 2, 9 Phase 3, 6 Phase 1.
Follow Menopause: new trials by email Literature Review of Menopause trials Research Report on Menopause
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Estradiol Supplementation and Rotator Cuff Repair Transdermal estrogen, Rotator Cuff Repair Surgery - Rotator Cuff Tears, Rotator Cuff Injuries | Phase 2 | Not yet recruiting | University of Utah | 58 | 2028-03-01 | 2026-03-19 |
| Focusing on the Menopausal Transition to Improve Mid-Life Women's Health Metformin, semaglutide, Anti-hypertensives - Menopause, Menopause Hot Flashes | Phase 2 / Phase 3 | Recruiting | University of Colorado, Denver | 200 | 2026-03-01 | 2026-11-04 |
| Effects of Hemp-Derived Cannabinoids on Menopause Symptoms Hemp-derived cannabinoids, Placebo - Menopause, Perimenopause | Phase 2 | Recruiting | Washington State University | 104 | 2026-02-11 | 2026-03-10 |
| Impact of Cannabinoids on Menopause Symptoms Active Cannabinoid Product, Placebo - Perimenopause, Menopause | Phase 2 | Completed | Washington State University | 104 | 2025-03-03 | 2026-06-02 |
| Analysis of the Hormonal Implant and Transdermal Estradiol Gel in Climacteric Women implantable estradiol, OESTROGEL - transdermal gel, PENTRAVAN - transdermal gel - Menopause, Hypoestrogenism | Phase 2 | Active not recruiting | Nutrindo Ideais Research Center | 50 | 2025-02-25 | 2026-08-10 |
| The Anabolic Effect of Testosterone on Pelvic Floor Muscles Testosterone cypionate, Placebo - Stress Urinary Incontinence, Menopause | Phase 2 | Active not recruiting | Brigham and Women's Hospital | 30 | 2025-02-15 | 2026-06-26 |
| The MUSE Study for Menopausal Arthralgia Menopausal hormone therapy, Exercise training, Menopausal hormone therapy + exercise training - Arthralgia, Menopause | Phase 2 / Phase 3 | Recruiting | National University Hospital, Singapore | 100 | 2024-08-01 | 2024-07-31 |
| A Study of NOE-115 in Women With Vasomotor Symptoms Due to Menopause NOE-115 - Menopause Syndrome, Menopause | Phase 2 | Completed | Noema Pharma AG | 40 | 2024-04-22 | 2025-09-12 |
| Effects of Novel Estrogens on Glucose and Lipids in Postmenopausal Prediabetic Women Veterans Placebo, conjugated estrogens/bazedoxifene (CE/BZA) - Menopause, Prediabetes | Phase 2 | Withdrawn | VA Office of Research and Development | 2024-04-08 | 2024-05-10 | |
| PhytoSERM to Prevent Menopause Associated Decline in Brain Metabolism and Cognition PhytoSERM, Placebo - Menopause, Cognitive Change | Phase 2 | Active not recruiting | Roberta Brinton | 100 | 2024-01-10 | 2026-03-13 |
| PhytoSERM for Menopausal Hot Flashes and Sustained Brain Health PhytoSERM, Placebo - Menopause, Hot Flashes | Phase 2 | Unknown | NeuTherapeutics | 132 | 2023-11-17 | 2024-01-02 |
| RCT on the Treatment of Menopausal Syndrome With Chinese Medicine Modified Guizhi Fuling granules, Placebo - Menopause | Phase 2 | Unknown | Chinese University of Hong Kong | 78 | 2023-11-01 | 2023-10-10 |
| The Menopause After Cancer Study Citalopram +/- Gabapentin + Sleepio + support person - Menopause, Cancer | Phase 2 | Completed | University College Dublin | 205 | 2021-06-21 | 2023-01-06 |
| FP-101 Versus Placebo in the Treatment of Menopausal Vasomotor Symptoms FP-101 - Vasomotor Symptoms, Menopause | Phase 2 | Completed | Fervent Pharmaceuticals | 105 | 2021-03-24 | 2023-10-26 |
| The Effects of a Novel Probiotic Supplement on Menopausal Symptoms and Bone Health Probiotic, Placebo - Menopause | Phase 2 | Completed | Lallemand Health Solutions | 144 | 2019-07-29 | 2023-02-02 |
| Stem Cell Therapy and Growth Factor Ovarian in Vitro Activation SEGOVA procedure - Menopause, Menopause Ovarian Failure | Phase 1 / Phase 2 | Unknown | Forever Young d.o.o. | 100 | 2019-06-01 | 2020-08-06 |
| Autologous PRP Intra Ovarian Infusion to Restore Ovarian Function in Menopausal Women Autologous PRP intra ovarian infusion, Autologous PFP intra ovarian infusion - Infertility, Female, Anovulatory Infertility | Phase 2 / Phase 3 | Recruiting | Genesis Athens Clinic | 100 | 2019-05-21 | 2026-07-08 |
| A Study of BAY3427080 (NT-814) in the Treatment of Moderate to Severe Post-menopausal Vasomotor Symptoms Elinzanetant (BAY3427080), Placebo - Menopause, Hot Flashes | Phase 2 | Completed | Bayer | 199 | 2018-11-20 | 2023-03-10 |
| Effect of Menopause Relief EP-40 in Women With Menopausal Symptoms Menopause Relief EP-40, Low Dose Black Cohosh, High Dose Black Cohosh - Menopause | Phase 2 | Completed | EuroPharma, Inc. | 220 | 2018-10-01 | 2020-04-28 |
| A Neurosteroid Intervention for Menopausal and Perimenopausal Depression Pregnenolone, Placebo - Major Depressive Disorder, Menopause | Phase 1 / Phase 2 | Completed | University of Texas Southwestern Medical Center | 73 | 2018-09-01 | 2026-01-22 |
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Hot Flashes (14) · Anxiety Disorders (4) · Breast Neoplasms (3) · Obesity (3) · Bone Diseases, Metabolic (2) · Depression (2) · Dyspareunia (2) · Mental Fatigue (2) · Osteoporosis (2) · Pain (2) · Sleep Initiation and Maintenance Disorders (2) · Amenorrhea (1) · Arthralgia (1) · Arthritis, Rheumatoid (1) · Atrophic Vaginitis (1)
Pathological Conditions, Signs and Symptoms (24) · Signs and Symptoms (22) · Urogenital Diseases (9) · Female Urogenital Diseases (8) · Female Urogenital Diseases and Pregnancy Complications (8) · Mental Disorders (8) · Genital Diseases (7) · Nutritional and Metabolic Diseases (7) · Behavior (6) · Genital Diseases, Female (6) · Metabolic Diseases (6) · Nervous System Diseases (6) · Musculoskeletal Diseases (5) · Behavioral Symptoms (4) · Male Urogenital Diseases (4)
Estradiol (6) · Progesterone (5) · Estrogens (3) · Estrogens, Conjugated (USP) (3) · Estrogens, Esterified (USP) (3) · Methyltestosterone (3) · black cohosh root extract (3) · Diet (2) · Exercise (2) · Hormone Replacement Therapy (2) · Medroxyprogesterone Acetate (2) · Prempro (2) · fezolinetant (2) · Angiotensin Receptor Antagonists (1) · Antihypertensive Agents (1)
National Center for Complementary and Integrative Health (NCCIH) (3) · Solvay Pharmaceuticals (3) · Chinese University of Hong Kong (2) · National Center for Research Resources (NCRR) (2) · University Potiguar (2) · University of Messina (2) · Washington State University (2) · Astellas Pharma Global Development, Inc. (1) · Ausio Pharmaceuticals, LLC (1) · Bayer (1) · Brigham and Women's Hospital (1) · Centro A.F. de Estudios Tecnologicos, S.A. (1) · Colorado State University (1) · Columbia University (1) · Dana-Farber Cancer Institute (1)
United States (37) · Brazil (4) · Canada (4) · China (2) · Mexico (2) · Australia (1) · France (1) · Georgia (1) · Greece (1) · Hong Kong (1) · Ireland (1) · Malta (1) · North Macedonia (1) · Serbia (1) · Singapore (1)
Gerson D Hernandez, MD, MPH (2) · Adi Cohen, MD (1) · Agni Pantou, MD (1) · Aleksandar Ljubic, MD, PhD (1) · Barbara Soltes, MD (1) · Cheryl M. Bourguignon, PhD, RN (1) · Christopher J Haines, FPOGS (1) · Dinalva B Queiroz, MsC (1) · Donal Brennan, PhD (1) · Dragana Lovre, MD (1) · Edward Sauter, MD (1)
PMID 24519196, PMID 17577003, PMID 19609225, PMID 21738077, PMID 21990811, PMID 22453200, PMID 22700728, PMID 23252963, PMID 24465425, PMID 27187320, PMID 29322164, PMID 30638769, PMID 31737860, PMID 31838497, PMID 32102086, PMID 32706883, PMID 33288437, PMID 34155864, PMID 3425152, PMID 34869938, PMID 37619252, PMID 37715710, PMID 3793432
M01RR000109 (2), 1IK2CX002225-01A1 (1), 2016 (1), 2018 (1), 2023 (1), M01RR000400 (1), P01HL045666 (1), R01AG075122 (1), R01DK136904 (1), R01MH083782 (1), R01MH087619 (1), R44AG019082 (1)