3 completed, 3 terminated, 2 active not recruiting, 1 not yet recruiting. 6 Phase 2, 2 Early Phase 1, 2 Phase 1, 1 Phase 3, 1 Phase 4.
Follow Methyltestosterone: new trials by email Literature Review of Methyltestosterone trials Research Report on Methyltestosterone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing the Use of High Dose Testosterone Followed by Darolutamide Compared to the Usual Care for Patients With Metastatic Prostate Cancer Abiraterone Acetate, Biospecimen Collection, Bone Scan - Metastatic Castration-Resistant Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 2 / Phase 3 | Not yet recruiting | ECOG-ACRIN Cancer Research Group | 432 | 2027-01-06 | 2026-10-01 |
| Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for Patients With Metastatic Castration Resistant Prostate Cancer Biopsy, Bone Scan, Computed Tomography - Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma | Phase 1 | Active not recruiting | Roswell Park Cancer Institute | 3 | 2024-12-19 | 2026-08-07 |
| Supraphysiological Androgen to Enhance Treatment Activity in Metastatic Castration-Resistant Prostate Cancer, SPECTRA Study Biopsy Procedure, Biospecimen Collection, Bone Scan - Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma | Phase 2 | Recruiting | University of Washington | 69 | 2024-05-21 | 2026-07-21 |
| Perioperative Testosterone Replacement Therapy for the Improvement of Post-Operative Outcomes in Patients With Low Testosterone Best Practice, Quality-of-Life Assessment, Questionnaire Administration - Hypogonadism, Malignant Urinary System Neoplasm | Phase 1 | Active not recruiting | Emory University | 56 | 2021-01-25 | 2026-05-26 |
| Mechanisms of Hypertension in Women With Polycystic Ovary Syndrome GnRH antagonist, GnRH antagonist + MethylTESTOSTERone 5 MG - Polycystic Ovary Syndrome, Hypertension | Early Phase 1 | Terminated | Yale University | 28 | 2017-12-01 | 2024-02-02 |
| Compromised Microcirculation in Women With Polycystic Ovary Syndrome ganirelix acetate, methyl testosterone - Polycystic Ovary Syndrome | Early Phase 1 | Completed | Yale University | 28 | 2008-02-01 | 2016-07-04 |
| Comparison of Estrogen and Methyltestosterone Combination Treatments for Postmenopausal Hot Flushes Esterified Estrogens (EE) and Methyltestosterone (MT) - Hot Flushes, Menopause, Postmenopause | Phase 2 | Completed | Solvay Pharmaceuticals | 1251 | 2005-06-01 | 2008-08-15 |
| Testosterone Replacement in Middle-Aged Hypogonadal Men With Dysthymia: Parallel Group, Double Blind Randomized Trial Testoviron - Dysthymic Disorder | Phase 4 | Unknown | Sheba Medical Center | 2004-09-01 | 2006-10-04 | |
| The Efficacy of ESTRATEST® Tablets in Relieving Menopausal Symptoms in Estrogenized, Hysterectomized Postmenopausal Women esterified estrogens 1.25mg and methyltestosterone 2.5mg, Esterified estrogens 1.25 mg - Menopause | Phase 2 | Terminated | Solvay Pharmaceuticals | 133 | 2004-07-01 | 2008-04-11 |
| The Efficacy of ESTRATEST® Tablets in Relieving Menopausal Symptoms in Estrogenized, Non-Hysterectomized Postmenopausal Women esterified estrogens 1.25 mg and methyltestosterone 2.5 mg, Esterified estrogens 1.25 mg - Menopause | Phase 2 | Terminated | Solvay Pharmaceuticals | 28 | 2004-07-01 | 2008-04-11 |
| Study of the Efficacy of ESTRATEST® H.S. Tablets in Relieving Menopausal Symptoms in Estrogenized Postmenopausal Women esterified estrogens 0.625 mg and methyltestosterone 1.25 mg - Menopause | Phase 2 | Completed | Solvay Pharmaceuticals | 350 | 2004-06-01 | 2015-01-16 |
Prostatic Neoplasms (3) · Polycystic Ovary Syndrome (2) · Dysthymic Disorder (1) · Hot Flashes (1) · Hypertension (1) · Hypogonadism (1) · Urologic Diseases (1) · Urologic Neoplasms (1)
Solvay Pharmaceuticals (4) · Yale University (2) · ECOG-ACRIN Cancer Research Group (1) · Emory University (1) · Roswell Park Cancer Institute (1) · Sheba Medical Center (1) · University of Washington (1)
United States (9) · Canada (1) · Israel (1) · Russia (1)
Michael Schweizer (2) · Nina Stachenfeld, PhD (2) · Guy Orr, MD (1) · Kenneth Ogan, MD (1) · Saby George, MD (1)
2005 (1), P30CA138292 (1), P50CA097186 (1), R01HL135089 (1), R21HL093450 (1), U10CA180820 (1)