101 completed, 24 terminated, 6 withdrawn, 1 active not recruiting. 53 Phase 3, 32 Phase 2, 24 Phase 4, 15 Phase 1, 7 Not applicable.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Investigate ADME of 14C Labeled SLV334 After an i.v. Infusion SLV 334 - Pharmacology, Clinical | Phase 1 | Completed | Solvay Pharmaceuticals | 6 | 2010-02-01 | 2010-09-17 |
| A Methodological Study To Evaluate The Effects of Single Oral Doses Of Pioglitazone 45 mg And Rosiglitazone 8 mg On Sodium Balance In Healthy Male Volunteers pioglitazone/rosiglitazone/placebo, rosiglitazone/pioglitazone/placebo, placebo/pioglitazone/rosiglitazone - Type 2 Diabetes Mellitus | Phase 1 | Completed | Solvay Pharmaceuticals | 12 | 2010-02-01 | 2010-03-17 |
| Study of Serum Testosterone Levels in Non-dosed Females After Secondary Exposure Testosterone gel 1.62% - Hypogonadism | Phase 1 | Completed | Solvay Pharmaceuticals | 24 | 2009-10-01 | 2009-11-25 |
| Effect of Testosterone Gel Replacement on Fat Mass in Males With Low Testosterone Levels and Diabetes Testosterone gel, placebo - Hypogonadism, Diabetes | Phase 4 | Withdrawn | Diabetes Center of the Southwest | 2009-08-01 | 2015-08-10 | |
| Hormone and Information Processing Study testosterone gel, placebo gel - Mild Cognitive Impairment, Alzheimer's Disease | Phase 3 | Completed | University of Washington | 22 | 2009-07-01 | 2014-07-14 |
| Interaction Study SLV337/Simvastatin Simvastatin- SLV337 SD beta- SLV337 SD alpha - SLV337 MD beta- SLV337 SD beta+ Simvastatin, Simvastatin - SLV337 SD alpha - SLV337 SD beta - SLV337 MD beta - SLV337 SD beta+ Simvastatin - Type 2 Diabetes Mellitus | Phase 1 | Completed | Solvay Pharmaceuticals | 16 | 2009-06-01 | 2009-09-09 |
| Safety and Tolerability of the First IV Dosing of SLV338 in Healthy Volunteers SLV338, Placebo - Healthy | Phase 1 | Completed | Solvay Pharmaceuticals | 42 | 2009-05-01 | 2010-01-29 |
| Study Investigating a Delayed-Release Pancrelipase in Patients With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis Pancrelipase Delayed Release - Cystic Fibrosis, Pancreatic Exocrine Insufficiency | Phase 3 | Completed | Solvay Pharmaceuticals | 19 | 2009-04-01 | 2010-11-08 |
| Duodenal Levodopa Infusion, Quality of Life and Autonomic Nervous System in Parkinson's Disease Levodopa infusion - Parkinson's Disease | Phase 4 | Completed | University of Helsinki | 12 | 2009-04-01 | 2011-02-24 |
| Safety and Efficacy Study to Evaluate the Effect of SLV320 on Renal Function in Patients With Worsening Heart Failure SLV320, Placebo - Acute Decompensated Heart Failure; Renal Dysfunction | Phase 2 | Terminated | Solvay Pharmaceuticals | 46 | 2009-02-01 | 2010-09-17 |
| Outcomes of Mechanically Ventilated Patients With Low Serum Testosterone Acute Respiratory Failure | Completed | The University of Texas Health Science Center, Houston | 28 | 2008-12-01 | 2010-09-21 | |
| First in Man Study With SLV341 SLV341, placebo - Diabetes | Phase 1 | Terminated | Solvay Pharmaceuticals | 87 | 2008-07-01 | 2010-04-28 |
| Study Investigating a Delayed-Release Pancrelipase in Patients With Pancreatic Exocrine Insufficiency (PEI) Due to Cystic Fibrosis (CF) Pancrelipase Delayed Release, Placebo Comparator - Cystic Fibrosis, Pancreatic Exocrine Insufficiency | Phase 3 | Completed | Solvay Pharmaceuticals | 17 | 2008-06-01 | 2010-06-02 |
| Palonosetron and Dexamethasone With or Without Dronabinol in Preventing Nausea and Vomiting in Patients Receiving Chemotherapy For Cancer dexamethasone, dronabinol, palonosetron hydrochloride - Chemotherapy-induced Nausea and Vomiting, Unspecified Adult Solid Tumor, Protocol Specific | Phase 3 | Completed | M.D. Anderson Cancer Center | 62 | 2008-05-01 | 2020-10-09 |
| Effects of Fenofibrate on Gene Expression in Healthy Volunteers Fenofibrate - Healthy | Phase 1 | Completed | Solvay Pharmaceuticals | 26 | 2008-03-01 | 2010-04-23 |
| BMS-646256 in Obese and Overweight Type 2 Diabetics ibipinabant - Obesity and Type 2 Diabetes | Phase 2 / Phase 3 | Withdrawn | Solvay Pharmaceuticals | 600 | 2008-03-01 | 2008-01-09 |
| Study Evaluating Multiple Ascending Dose in Schizophrenia Patients SLV-313 SR - Healthy | Phase 1 | Terminated | Wyeth is now a wholly owned subsidiary of Pfizer | 32 | 2008-02-01 | 2009-08-04 |
| Dose-ranging Study to Evaluate Efficacy of SLV339 in Pancreatic Exocrine Insufficiency Due to Chronic Pancreatitis Placebo, Recombinant Microbial Lipase SLV339 - Pancreatic Exocrine Insufficiency Due to Chronic Pancreatitis | Phase 2 | Terminated | Solvay Pharmaceuticals | 56 | 2008-02-01 | 2009-08-06 |
| Study Evaluating the Safety and Tolerability of Single Ascending Dose (SAD) SLV-351 in Healthy Subjects SLV-351 - Healthy | Phase 1 | Terminated | Wyeth is now a wholly owned subsidiary of Pfizer | 72 | 2008-01-01 | 2009-08-04 |
| Study Evaluating Safety and Tolerability of Ascending Multiple Dose of SLV-313 in Schizophrenia Patients SLV-313 SR - Healthy | Phase 1 | Terminated | Wyeth is now a wholly owned subsidiary of Pfizer | 32 | 2008-01-01 | 2022-05-03 |
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Hypogonadism (19) · Schizophrenia (12) · Diabetes Mellitus, Type 2 (10) · Parkinson Disease (9) · Dyslipidemias (7) · Exocrine Pancreatic Insufficiency (7) · Obesity (7) · Diabetes Mellitus (6) · Influenza, Human (6) · Psychotic Disorders (5) · Cystic Fibrosis (4) · Depression (4) · Glucose Metabolism Disorders (4) · Hypertension (4) · Nausea (4)
Fenofibrate (17) · Testosterone (17) · bifeprunox (13) · Metformin (6) · pardoprunox (6) · Dronabinol (5) · Estrogens, Esterified (USP) (4) · Methyltestosterone (4) · Pancrelipase (4) · Pharmaceutical Preparations (4) · Simvastatin (4) · Dydrogesterone (3) · Estradiol (3) · Omacor (3) · SLV320 compound (3)
United States (66) · Germany (21) · Poland (18) · France (16) · Russia (14) · Ukraine (14) · United Kingdom (13) · Czechia (12) · Italy (11) · South Africa (11) · Bulgaria (10) · Canada (10) · Finland (10) · Hungary (10) · Romania (10)
Toshiaki Yamaguchi (2) · Alin Stirban, MD (1) · Alvin M Matsumoto, MD (1) · Amal I. Melhem-Bertrandt, MD (1) · Andrzej Ciszewski, MD, PhD (1) · Anita Vanderlaan (1) · Antonie Beiske, PhD, M.D. (1) · Ben Z Leder, MD (1) · Christofer Lundqvist, PhD, M.D. (1) · Christopher P Cardozo, M.D. (1) · Claire Nee (1)
PMID 21542016, PMID 17105798, PMID 18187561, PMID 19331437, PMID 19361304, PMID 19653976, PMID 19815466, PMID 19919976, PMID 20171415, PMID 20297950, PMID 20520285, PMID 21575967, PMID 21641345, PMID 21681115, PMID 22188558, PMID 22212377, PMID 22316635, PMID 22419719, PMID 22939385, PMID 24024838, PMID 24356795, PMID 24622263, PMID 25392748, PMID 26262795, PMID 26901812, PMID 27377542, PMID 27754805, PMID 27992261, PMID 28981994, PMID 29373734, PMID 29653635, PMID 30146931, PMID 30146932, PMID 30898204, PMID 31986094, PMID 32480409, PMID 35393614, PMID 36871000, PMID 38052385, PMID 38237868, PMID 38385506, PMID 39501183, PMID 40010818
2004 (14), 2005 (8), 2009 (3), 2008 (2), R01AG027156 (1), R01AG030545 (1)