85 completed, 25 recruiting, 21 unknown, 8 not yet recruiting. 76 Not applicable, 20 Phase 3, 15 Phase 2, 9 Phase 4, 3 Early Phase 1.
Follow Dyspareunia: new trials by email Literature Review of Dyspareunia trials Research Report on Dyspareunia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PRECISION-E2: Teverelix in Women With Endometriosis - Pharmacodynamics, Safety and Precision Medicine Correlates Teverelix DP, Teverelix DP Placebo - Endometriosis Pelvic, Endometriosis Ovaries | Phase 2 | Not yet recruiting | Antev Ltd. | 84 | 2027-02-01 | 2026-11-03 |
| RELIEVE Study- Platelet-Rich Plasma to Reduce Postpartum Pain After Perineal Tears or Episiotomy Autologous Non-Activated Platelet-Rich Plasma, Saline (0.9%, sterile, for infusion) - Perineal Trauma, Postpartum Pain | Not applicable | Not yet recruiting | University Hospital, Geneva | 160 | 2026-10-01 | 2026-07-27 |
| The PANHIS Study: Sexual Health in Spanish-Speaking Adults - A Cross-Sectional Online Survey Sexual Health, Sexual Dysfunction, Physiological | Recruiting | Menoclinica by Palacios | 15000 | 2026-08-30 | 2026-09-01 | |
| VEDA Study (DHEA vs Estradiol) DHEA ovals, Estradiol 0.01% Vag Cream - Post-menopause, Pre-menopause | Not applicable | Recruiting | University of Arizona | 324 | 2026-08-04 | 2026-09-21 |
| F-GYN for Vaginal Dryness and Vulvovaginal Atrophy F-GYN Non-Crosslinked Hyaluronic Acid Injectable Gel, Standard Non-Hormonal Symptomatic Care - Atrophic Vaginitis, Atrophic Vulvovaginitis | Not applicable | Recruiting | Biovico Sp. z o.o. | 130 | 2026-07-24 | 2026-10-01 |
| Proof of Concept Study of Vaginal AZU-101 in Vulvovaginal Atrophy in Postmenopausal Women Lasofoxifene Tartrate - Vulvo Vaginal Atrophy (VVA) | Phase 2 | Recruiting | Azure Biotech Inc. | 90 | 2026-07-01 | 2026-10-19 |
| Retrospective Cohort Study of Symptoms and Quality of Life in Women With Genitourinary Syndrome of Menopause. Vulvar Atrophy, Vulvovaginal Signs and Symptoms | Not yet recruiting | Mucosa Innovations, S.L. | 100 | 2026-07-01 | 2026-07-30 | |
| Comparing Decidual Inclusion vs. Exclusion in Uterine Suture Techniques During Cesarean Section to Improve Scar Thickness and Reduce Isthmocele Risk in Primiparous Women Single-Layered Non-Locked Closure with Decidual Inclusion, Single-Layered Non-Locked Closure with Decidual Sparing - Isthmocele, Cesarean Scar Diverticula | Not applicable | Recruiting | Kantonsspital Baden | 374 | 2026-06-17 | 2026-08-25 |
| Effects of Clinical Pilates on Pain and Quality of Life in Women With Dyspareunia Clinical Pilates Exercise - Dyspareunia | Not applicable | Completed | Okan University | 20 | 2026-04-06 | 2026-10-21 |
| Effectiveness of Radiofrequency Combined With Ultrasound for the Treatment of Postpartum Dyspareunia Combining radiofrequency and ultrasound. BTL Exilis - Dyspareunia | Not applicable | Recruiting | Institut Investigacio Sanitaria Pere Virgili | 34 | 2026-04-01 | 2026-04-16 |
| Bipolar Radiofrequency for Genitourinary Syndrome of Menopause Active bipolar radiofrequency therapy, Sham radiofrequency procedure - Genitourinary Syndrome of Menopause (GSM) | Not applicable | Not yet recruiting | University of Castilla-La Mancha | 40 | 2026-03-15 | 2026-02-18 |
| Pelvic Floor Physical Therapy and Exercise for Women With Endometriosis and Chronic Pelvic Pain Pelvic Floor Physical Therapy, Placebo Pelvic Floor Physical Therapy, Physical Exercise - Endometriosis, Chronic Pelvic Pain | Not applicable | Recruiting | Hospital de Clinicas de Porto Alegre | 64 | 2026-03-05 | 2026-07-29 |
| Use of Topical Testosterone and Estrogen vs Estrogen Alone in Vulvodynia: a Randomized Controlled Trial Estradiol 0.01% Vag Cream, testosterone 0.1% and estradiol 0.01% vaginal cream - Vulvodynia, Dyspareunia | Phase 2 / Phase 3 | Not yet recruiting | TriHealth Inc. | 44 | 2025-12-01 | 2025-12-03 |
| Effect of Respiratory Exercises With Pelvic Floor Rehab on Dyspareunia & Autonomic Function in Women Pelvic floor rehabilitation, Diaphragmatic Breathing Exercises, Diaphragm Manual Therapy - Dyspareunia (Female Excluding Psychogenic), Female Sexual Dysfunction (FSD) | Not applicable | Not yet recruiting | Sakarya Applied Sciences University | 45 | 2025-09-01 | 2025-07-22 |
| Effects of Pelvic Floor Muscle Training With & Without Hypopressive Exercises hypopressive excercises, pelvic training excercises - Pelvic Organ Prolapse | Not applicable | Recruiting | Riphah International University | 51 | 2025-08-01 | 2026-02-27 |
| Impact of Ehlers-Danlos Syndrome on Gynaecological Health Ehlers-Danlos Syndrome (EDS) | Recruiting | University Hospital, Rouen | 156 | 2025-07-07 | 2026-06-10 | |
| Physiotherapeutic Approach to Superficial and Deep Dyspareunia in Women With Chronic Pelvic Pain: Comparison Between In-person and Telehealth Care. Face-to-face treatment, Telecare - Surface and Deep Dyspareunia | Not applicable | Active not recruiting | University of Sao Paulo | 72 | 2025-05-16 | 2026-06-22 |
| Effectiveness of a Telerehabilitation Program for Improving Sexual Function and Reducing Pain in Menopausal Women Pelvify: Menopause and dyspareunia treatment, Face to Face Physical Therapy Protocol, Face to Face Protocol Combined With an Asynchronous Telerehabilitation Program - Menopause, Genitourinary Syndrome of Menopause | Not applicable | Recruiting | Instituto Médico Tecnológico SL | 90 | 2025-05-05 | 2025-05-23 |
| Biomodulation and Rehabilitation Interventions to tarGet Pelvic Health Photobiomodulation, Sham photobiomodulation, Multimodal physiotherapy - Vulvodynia, Provoked Vestibulodynia | Not applicable | Recruiting | University of Ottawa | 240 | 2025-03-17 | 2026-05-05 |
| Study of Sexual Quality of Life in Women With Breast Cancer Who Had Multidisciplinary Management With Photobiomodulation for Genitourinary Syndrome of the Menopause Questionnaires given before and after photobiomodulation - Breast Cancer | Not applicable | Recruiting | Institut du Cancer de Montpellier - Val d'Aurelle | 25 | 2025-03-13 | 2025-11-18 |
Showing 20 of 152. Sign in to see all of them.
Endometriosis (32) · Dysmenorrhea (25) · Sexual Dysfunction, Physiological (22) · Pelvic Pain (20) · Vulvodynia (17) · Pain (14) · Breast Neoplasms (10) · Vaginismus (9) · Constipation (7) · Infertility (7) · Urinary Incontinence (7) · Dysuria (5) · Sexual Dysfunctions, Psychological (4) · Vaginitis (4)
Female Urogenital Diseases (152) · Female Urogenital Diseases and Pregnancy Complications (152) · Genital Diseases (152) · Genital Diseases, Male (152) · Male Urogenital Diseases (152) · Mental Disorders (152) · Urogenital Diseases (152) · Genital Diseases, Female (151) · Sexual Dysfunctions, Psychological (148) · Sexual Dysfunction, Physiological (130) · Pathological Conditions, Signs and Symptoms (62) · Signs and Symptoms (60) · Neurologic Manifestations (48) · Pain (32) · Pathologic Processes (27)
Estradiol (9) · linzagolix (5) · Vaginal Creams, Foams, and Jellies (4) · Botulinum Toxins, Type A (3) · Dehydroepiandrosterone (3) · Exercise (3) · Musculoskeletal Manipulations (3) · Physical Therapy Modalities (3) · Surveys and Questionnaires (3) · Testosterone (3) · asoprisnil (3) · Coconut Oil (2) · Cognitive Behavioral Therapy (2) · Laser Therapy (2) · Lidocaine (2)
Kissei Pharmaceutical Co., Ltd. (4) · Abbott (3) · BC Women's Hospital & Health Centre (3) · Kanuni Sultan Suleyman Training and Research Hospital (3) · Medstar Health Research Institute (3) · Ohio State University Comprehensive Cancer Center (3) · Riphah International University (3) · Cairo University (2) · Corewell Health East (2) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (2) · Hadassah Medical Organization (2) · Hospital de Clinicas de Porto Alegre (2) · Mucosa Innovations, S.L. (2) · National and Kapodistrian University of Athens (2) · Reckitt Benckiser Healthcare (UK) Limited (2)
United States (55) · Spain (18) · Canada (16) · Brazil (11) · Poland (7) · Turkey (Türkiye) (7) · Belgium (6) · France (5) · Switzerland (5) · Bulgaria (4) · Czechia (4) · Italy (4) · Romania (4) · Ukraine (4) · Australia (3)
Allison Quick, MD (2) · Christel LC Meuleman, MD (2) · Irwin Goldstein, MD (2) · Judith M. Schlaeger, PhD (2) · Lori A Brotto, PhD (2) · Stavros Athanasiou, Associate Proffesor (2) · Thomas D'Hooghe, MD, PhD (2) · Ahinoam Lev-Sagie, MD (1) · Ahmed S Alharty, MD (1)
PMID 10782451, PMID 32734597, PMID 37619252, PMID 40709601, PMID 11489726, PMID 12050564, PMID 14583935, PMID 15089868, PMID 15189832, PMID 15804736, PMID 16407018, PMID 16648432, PMID 17195176, PMID 17262148, PMID 18053998, PMID 18978095, PMID 19140047, PMID 19170834, PMID 19222415, PMID 19337252, PMID 19663710, PMID 20092441, PMID 22232129, PMID 22426487, PMID 22969138, PMID 23481118, PMID 23812462, PMID 23848490, PMID 23921822, PMID 24074537, PMID 24807329, PMID 25099244, PMID 25137424, PMID 25345486, PMID 25540035, PMID 26136488, PMID 26215946, PMID 26410801, PMID 26524223, PMID 26906970, PMID 27008217, PMID 27383445, PMID 27443813, PMID 27823751, PMID 28027568, PMID 28120373, PMID 28355090, PMID 28363809, PMID 28383379, PMID 28391147
2017 (1), 2023 (1)