223 completed, 34 unknown, 28 recruiting, 20 terminated. 144 Not applicable, 69 Phase 3, 67 Phase 2, 25 Phase 1, 21 Phase 4.
Follow Hot Flashes: new trials by email Literature Review of Hot Flashes trials Research Report on Hot Flashes
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Acupuncture With/Without Self-acupressure for Post-oophorectomy Hot Flashes in BRCA Carriers Acupuncture, Acupuncture-Acupressure - Hot Flashes, Menopause Surgical | Not applicable | Not yet recruiting | Shaare Zedek Medical Center | 200 | 2026-12-01 | 2026-04-29 |
| Effects of a Dietary Supplement in Women With Late Perimenopause or Early Postmenopause Plant Extract-Based Dietary Supplement, Placebo - Perimenopause, Postmenopause | Not applicable | Recruiting | University of Alicante | 120 | 2026-11-01 | 2026-10-13 |
| A Study to Confirm if Fezolinetant Helps to Reduce Hot Flashes in Indian Women Going Through Menopause Fezolinetant - Hot Flashes | Phase 3 | Not yet recruiting | Astellas Pharma Inc | 100 | 2026-10-31 | 2026-09-28 |
| Goji Berry and Vasomotor Symptoms Pilot Study Goji Berry Juice Powder, Goji Berry Powder - Vasomotor Symptoms | Not applicable | Not yet recruiting | University of California, Davis | 6 | 2026-10-25 | 2026-08-18 |
| Internet-Delivered CBT Program for Menopausal Vasomotor Symptoms Internet-delivered Cognitive Behavioural Therapy - Menopause, Menopausal Vasomotor Symptoms | Not applicable | Not yet recruiting | St. Joseph's Healthcare Hamilton | 50 | 2026-10-13 | 2026-10-20 |
| Self-Management Box on Hot Flash in Postmenopausal Women Components of Nurse-Led Menopause Self- Management Box - Postmenopausal Flushing, Postmenopausal Symptoms | Not applicable | Not yet recruiting | Mansoura University | 120 | 2026-10-08 | 2026-10-15 |
| Reduce HEAT: A Randomized Trial of Wearable Thermal Devices for ADT-Induced Hot Flashes Embr Wave - Prostate Cancer, Hot Flashes | Not applicable | Recruiting | Dana-Farber Cancer Institute | 66 | 2026-10-01 | 2026-09-25 |
| Fezolinetant and Vascular Health and Brain Health Placebo, Fezolinetant - Menopause Hot Flashes | Phase 3 | Not yet recruiting | Rebecca Thurston | 220 | 2026-09-25 | 2026-08-19 |
| Haelan 951 for Menopause Symptoms in Peri- and Postmenopausal Women Haelan 951 - Menopause, Menopause Hot Flashes | Not applicable | Recruiting | Spectrum Clinical Research, LLC | 25 | 2026-09-21 | 2026-09-11 |
| Targeting Insomnia to Prevent Depression in the Menopause Transition digital cognitive behavioral therapy for insomnia, Digital sleep hygiene education - Insomnia, Menopause Related Conditions | Not applicable | Not yet recruiting | SRI International | 230 | 2026-09-01 | 2026-03-02 |
| Randomized Evaluation of Natural Extract for Menopausal Wellness (RENEW) Shatavari (Asparagus racemosus) Extract, Placebo - Menopause, Hot Flashes | Not applicable | Recruiting | India Glycols Ltd | 100 | 2026-09-01 | 2026-09-22 |
| Comparing Acupuncture vs. Sham Acupuncture for the Management of Hot Flashes in Prostate Cancer Patients Receiving Hormone Therapy Real Acupuncture, Sham Acupuncture - Accupuncture, Prostate Cancer | Not applicable | Recruiting | University of Kentucky | 40 | 2026-08-13 | 2026-08-18 |
| Intra Ovarian Muse Cell Injection for Perimenopause Symptom Relief and Ovarian Function Restoration (MUSE-OVARY) Perimenopause, Perimenopause-Related Depression | Enrolling by invitation | Healing Hope International | 12 | 2026-06-01 | 2026-04-06 | |
| A Retrospective and Prospective Clinical Registry for Data Collection of Perimenopausal, Menopausal and Premature Ovarian Insufficiency Women Menopause, Menopausal Hormone Therapy | Not yet recruiting | IRCCS San Raffaele | 5000 | 2026-06-01 | 2026-05-26 | |
| A Feasibility Study of Biometric Measurements Via Wearable Smart Watch Technology for Evaluation of Vasomotor Symptoms in Patients Treated With Androgen Deprivation Therapy for Prostate Cancer (Prostate 007) VMS logging - Prostate Cancer, Hot Flashes | Not applicable | Recruiting | University of Virginia | 18 | 2026-05-21 | 2026-06-09 |
| Effect of a Mindfulness-Based Stress Reduction Program on Hot Flashes and Sleep Quality in Menopausal Women: A Randomized Controlled Trial Mindfulness-Based Stress Reduction (MBSR) - Menopause, Hot Flashes | Not applicable | Not yet recruiting | Inonu University | 90 | 2026-05-15 | 2026-02-11 |
| The Effect of Cold Packs on Hot Flushes and Depression in Women Going Through the Climacteric Period Cold gel packs application - Hot Flashes, Climactericum | Not applicable | Completed | Rabia Atilla | 60 | 2026-04-13 | 2026-08-13 |
| The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity Tirzepatide, Placebo - Obesity, Menopause Hot Flashes | Phase 4 | Recruiting | Mayo Clinic | 40 | 2026-04-08 | 2026-10-06 |
| A Randomized Controlled Trial of Acupuncture for the Management of Hot Flashes in Patients With Hormone Receptor-Positive Breast Cancer True Acupuncture, Sham Acupuncture - Acupuncture Treatment, Hormone Receptor-Positive Breast Cancer | Not applicable | Not yet recruiting | Peking University People's Hospital | 60 | 2026-04-01 | 2026-03-19 |
| Finding Links Between Hot flASHes and CardioVascular Disease elinzanetant - reference formulation, placebo - Menopause-related Hot Flashes | Phase 2 | Recruiting | Massachusetts General Hospital | 80 | 2026-03-01 | 2026-05-20 |
Showing 20 of 334. Sign in to see all of them.
Breast Neoplasms (59) · Prostatic Neoplasms (22) · Depression (16) · Sleep Initiation and Maintenance Disorders (12) · Anxiety Disorders (11) · Breast Carcinoma In Situ (10) · Fever (10) · Multiple Endocrine Neoplasia Type 1 (9) · Infections (8) · Neutropenia (8) · Burkitt Lymphoma (7) · Carcinoma, Intraductal, Noninfiltrating (7) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (7) · Fatigue (6)
Pathological Conditions, Signs and Symptoms (334) · Signs and Symptoms (334) · Neoplasms (92) · Neoplasms by Site (92) · Breast Diseases (59) · Skin Diseases (59) · Skin and Connective Tissue Diseases (59) · Mental Disorders (32) · Urogenital Diseases (32) · Genital Diseases (31) · Nervous System Diseases (29) · Urogenital Neoplasms (26) · Male Urogenital Diseases (25) · Genital Diseases, Male (24) · Genital Neoplasms, Male (24)
fezolinetant (18) · Acupuncture Therapy (16) · Gabapentin (14) · Estradiol (13) · black cohosh root extract (10) · Venlafaxine Hydrochloride (8) · Paroxetine (7) · Estrogens, Conjugated (USP) (6) · Hypnosis (6) · Soybean Proteins (6) · Sugars (6) · Bupivacaine (5) · Progesterone (5) · Citalopram (4) · Estetrol (4)
Bayer (18) · Mayo Clinic (13) · Alliance for Clinical Trials in Oncology (10) · Massachusetts General Hospital (9) · Astellas Pharma Global Development, Inc. (7) · Cairo University (6) · National Center for Complementary and Integrative Health (NCCIH) (6) · Wake Forest University Health Sciences (6) · Northwestern University (5) · University of California, San Francisco (5) · Astellas Pharma Inc (4) · Baylor University (4) · Depomed (4) · Fred Hutchinson Cancer Center (4) · Bionovo (3)
United States (189) · Canada (28) · United Kingdom (23) · Germany (16) · Spain (15) · Italy (14) · China (13) · Turkey (Türkiye) (11) · Belgium (10) · France (10) · Netherlands (10) · Brazil (9) · Czechia (9) · Poland (9) · Egypt (8)
Charles L. Loprinzi, MD (4) · Deborah Grady, MD, MPH (4) · Andrea Z LaCroix, PhD (3) · Charles Loprinzi, MD (3) · Debra Barton, RN, PhD, AOCN, FAAN (3) · Ellen W Freeman, PhD (3) · Katherine M Newton, PhD (3) · Lee S Cohen, MD (3) · Thomas J. Walsh, MD (3) · Ashley Tunkle, MD (2)
PMID 29165623, PMID 32701665, PMID 23760428, PMID 26241433, PMID 39739195, PMID 36809193, PMID 37990323, PMID 38396203, PMID 38775925, PMID 39172446, PMID 40044127, PMID 41259888, PMID 41289787, PMID 101855, PMID 10404417, PMID 11256098, PMID 12638461, PMID 15012887, PMID 15099854, PMID 15345062, PMID 15459300, PMID 15806544, PMID 16139656, PMID 16186076, PMID 16194125, PMID 16414334, PMID 16414336, PMID 16505409, PMID 16782922, PMID 16816054, PMID 17146104, PMID 17179056, PMID 17227907, PMID 17329509, PMID 17400842, PMID 17453860, PMID 17487652, PMID 17906008, PMID 18065731, PMID 18202966, PMID 18375894, PMID 18515518, PMID 18591315, PMID 18809612, PMID 19129205, PMID 19265726, PMID 19305337, PMID 19609225, PMID 19888035, PMID 20025635
P30CA015083 (4), U01AG032699 (4), 2018 (3), 2005 (2), 2015 (2), U01AG032700 (2), U10CA081851 (2), 1IK2CX002225-01A1 (1), 2004 (1), 2009 (1), 2019 (1), 2023 (1), K01HL148144 (1), K23MH066978 (1), K23NR014008 (1)