12 completed, 3 unknown, 1 enrolling by invitation, 1 withdrawn. 17 Phase 2, 5 Phase 1, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 17 | Completed 12, Unknown 3, Enrolling by invitation 1, Withdrawn 1 |
| Phase 1 | 5 | Completed 4, Enrolling by invitation 1 |
| Phase 3 | 3 | Completed 2, Unknown 1 |
Follow Maxillofacial Abnormalities: new trials by email Literature Review of Maxillofacial Abnormalities trials Research Report on Maxillofacial Abnormalities
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating the Accuracy of Soft Tissue Prediction in Patients With Mandibular Prognathism After Orthognathic Surgery Using Handheld Scanner Versus Optical Scanner A Prospective Clinical Trial face scanning pre and post orthognathic surgery - Mandibular Prognathism, Orthognathic Surgery | Phase 1 / Phase 2 | Enrolling by invitation | Cairo University | 11 | 2024-09-24 | 2024-12-09 |
| Augmented Reality for Orthognatic Surgery Patient Education Patient consultation - Malocclusion, Dentofacial Deformities | Phase 2 / Phase 3 | Completed | University Medical Center Groningen | 60 | 2023-10-01 | 2025-03-30 |
| Pharmacological Treatment on the Recovery of Neurosensory Disturbance After Bilateral Sagittal Split Osteotomy Orthognathic Surgery, Melatonin 10 MG Oral Tablet, Hydroxycobalamin - Retrognathism, Prognathism | Phase 2 / Phase 3 | Unknown | Universitat Internacional de Catalunya | 220 | 2022-09-30 | 2022-09-13 |
| Dexmedetomidine Versus Sevoflurane in Children With Anticipated Difficult Intubation dexmedetomidine, sevoflurane - Craniofacial Abnormalities, Mandibular Hypoplasia | Phase 2 | Unknown | Alexandria University | 40 | 2020-06-01 | 2020-06-12 |
| Suprazygomatic Block in Cleft Palate Surgery in Children Bupivacaine, Dexmedetomidine, paracetamol - Cleft Palate | Phase 2 | Completed | Assiut University | 80 | 2018-01-14 | 2018-09-24 |
| Does it Worth to Reinforce With Additional Anesthesia to Improve Postoperative Course After Orthognathic Surgery? Second infiltration pre-extubation with ropivacaine - Dentofacial Deformities | Phase 2 | Completed | Servei Central d'Anestesiologia | 52 | 2018-01-10 | 2020-02-13 |
| Effects of Oral Melatonin on Neurosensory Recovery Following Facial Osteotomies Oral Melatonin 10mg, Placebo - Dentofacial Deformities | Phase 2 | Unknown | The University of Hong Kong | 40 | 2016-06-01 | 2016-09-07 |
| Comparative Study Between Levobupivacaine and Bupivacaine for Nerve Block During Pediatric Primary Cleft Palate Surgery Levobupivacaine, Bupivacaine - Recovery After Cleft Palate Surgery | Phase 2 / Phase 3 | Completed | Assiut University | 60 | 2016-01-01 | 2017-09-07 |
| IV Acetaminophen in Children Undergoing Palatoplasty IV acetaminophen, Placebo - Cleft Palate | Phase 2 | Withdrawn | Nationwide Children's Hospital | 2015-12-01 | 2016-03-08 | |
| Botulinum Toxin to Improve Cosmesis of Primary Cleft Lip Repair Botulinum Toxin Type A, Normal Saline Injection - Cleft Lip, Scarring | Phase 1 / Phase 2 | Completed | The University of Texas Health Science Center, Houston | 30 | 2015-12-01 | 2021-11-03 |
| Description of Pain in Pediatric Patients With Cleft Lip and Palate Undergoing Alveolar Grafting Using Two Surgical Strategies: Stem Cells and Autogenous Iliac Crest Bone (Pain Evaluation in Children Undergoing Alveolar Grafting: Stem Cells vs. Iliac Crest Bone) Autogenous Iliac Crest Bone Grafting, Bioengineered Alveolar Grafting (SHED + Scaffold) - Clift Lip, Cleft Palate | Phase 1 / Phase 2 | Completed | Hospital Sirio-Libanes | 20 | 2015-03-01 | 2026-07-29 |
| Applicability Clinic of Cement Portland Structural White in Endodontic Surgery ENDODONTIC SURGERY - Mandibular Hypoplasia | Phase 1 / Phase 2 | Completed | Universidade do Vale do Sapucai | 12 | 2013-02-01 | 2015-06-18 |
| Cell Therapy for Craniofacial Bone Defects Ixmyelocel-T, Autogenous Bone Grafting - Cleft Palate, Trauma | Phase 1 / Phase 2 | Completed | University of Michigan | 18 | 2012-08-01 | 2017-05-04 |
| Does Use of Rigid Fixation After Removing Distraction Osteogenesis Device Reduce the Relapse? mini plate - Cleft Palate, Maxillary Hypoplasia | Phase 2 | Completed | Shiraz University of Medical Sciences | 20 | 2011-02-01 | 2015-01-30 |
| Preventing Complications in Cleft Palate Repair With Antibiotics Unasyn, saline solution - Cleft Palates | Phase 2 | Completed | Joseph Losee | 224 | 2008-05-01 | 2018-02-01 |
| Cleft Orthognathic Surgery Versus Distraction Osteogenesis - Which is Better? Orthognathic surgery, Distraction osteogenesis - Cleft Lip and Palate, Maxillary Hypoplasia | Phase 2 | Completed | The University of Hong Kong | 60 | 2002-06-01 | 2011-09-13 |
| Cleft Palate Surgery and Speech Development Furlow double z-plasty palatoplasty palate repair, Von Langenbeck palatoplasty palate repair - Cleft Lip, Cleft Palate | Phase 2 | Completed | University of Florida | 475 | 1996-02-01 | 2011-09-20 |
Cleft Palate (9) · Cleft Lip (4) · Dentofacial Deformities (3) · Retrognathia (3) · Micrognathism (2) · Prognathism (2) · Alveolar Bone Loss (1) · Cicatrix (1) · Craniofacial Abnormalities (1) · Malocclusion (1) · Malocclusion, Angle Class III (1) · Pain, Postoperative (1) · Patient Satisfaction (1) · Sensation Disorders (1) · Speech (1)
Congenital Abnormalities (17) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (17) · Musculoskeletal Abnormalities (17) · Musculoskeletal Diseases (17) · Stomatognathic Diseases (17) · Stomatognathic System Abnormalities (17) · Craniofacial Abnormalities (16) · Jaw Abnormalities (14) · Jaw Diseases (14) · Mouth Abnormalities (10) · Mouth Diseases (10) · Lip Diseases (4) · Mandibular Diseases (4) · Pathological Conditions, Signs and Symptoms (3)
Acetaminophen (2) · Bupivacaine (2) · Dexmedetomidine (2) · Melatonin (2) · Orthognathic Surgery (2) · Saline Solution (2) · Ampicillin (1) · Botulinum Toxins, Type A (1) · Cytidine (1) · Hydroxocobalamin (1) · Levobupivacaine (1) · Osteogenesis, Distraction (1) · Ropivacaine (1) · Sevoflurane (1) · Sulbactam (1)
Assiut University (2) · The University of Hong Kong (2) · Alexandria University (1) · Cairo University (1) · Hospital Sirio-Libanes (1) · Joseph Losee (1) · Nationwide Children's Hospital (1) · Servei Central d'Anestesiologia (1) · Shiraz University of Medical Sciences (1) · The University of Texas Health Science Center, Houston (1) · Universidade do Vale do Sapucai (1) · Universitat Internacional de Catalunya (1) · University Medical Center Groningen (1) · University of Florida (1) · University of Michigan (1)
United States (5) · Egypt (4) · Brazil (2) · Hong Kong (2) · Germany (1) · Iran (1) · Netherlands (1) · Spain (1)
Crystal TY Lee, BDS (HKU) (1) · Daniela Francescato Veiga (1) · Darnell Kaigler, DDS, PhD (1) · J Kraeima, dr. (1) · Jaecel O Shah, MD (1) · Joseph Losee, MD (1) · Lim K Cheung, BDS, PhD (1) · Miriam DeNadal, MD, PhD (1) · Mohamed Ahmed Farid, Professor of OMFS (1) · Negin Matini, DMD (1) · Pedro Sole, DMD, OMFS (1) · Rehab A. Abd Elaziz, Ass.Prof. (1) · Reza Tabrizi, DMD (1)
PMID 20443823, PMID 21120277, PMID 23117614, PMID 42069961
R01DE010437 (1)