13 completed, 8 unknown, 2 terminated, 1 not yet recruiting. 8 Not applicable, 3 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Unknown 4, Completed 3, Terminated 1 |
| Phase 3 | 3 | Completed 1, Recruiting 1, Terminated 1 |
| Phase 4 | 1 | Completed 1 |
Follow Major Trauma: new trials by email Literature Review of Major Trauma trials Research Report on Major Trauma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Blood Storage Related Mortality and Adverse Effects in Trauma Patients Transfusion Adverse Reaction, Major Trauma | Completed | Kocaeli City Hospital | 101 | 2026-01-17 | 2026-08-07 | |
| The NRC Dataset. Developing a Minimum Dataset for Multidisciplinary Rehabilitation: a Modified E-Delphi Study Pain, Traumatic Brain Injury | Not yet recruiting | ThomasCorbett | 50 | 2025-01-01 | 2024-12-19 | |
| Calcium Levels in Major Trauma ionized calcium levels - Major Trauma | Unknown | Hossam Abdel Rahman Ahmed Ismail | 150 | 2024-03-01 | 2023-10-26 | |
| Shock and Acute Conditions OutcOmes Platform Inotrope, Mechanical circulatory support, anti-bodies - Circulatory Shock, Sepsis | Unknown | Saint-Louis Hospital, Paris, France | 1000 | 2024-01-01 | 2024-04-19 | |
| Enhanced Rehabilitation After Major Trauma (PROPERLY) Enhanced Rehabilitation Programme, Standard Care - Major Trauma | Not applicable | Completed | Manchester University NHS Foundation Trust | 55 | 2023-02-24 | 2026-07-17 |
| Arterial Line in Trauma Resuscitation arterial line - Major Trauma | Not applicable | Unknown | National Taiwan University Hospital | 216 | 2023-01-01 | 2024-11-13 |
| The Effects of Acupuncture for Major Trauma Electroacupuncture (EA), Laser acupuncture (LA), Sham laser acupuncture (SLA) - Major Trauma | Not applicable | Unknown | Chang Gung Memorial Hospital | 180 | 2021-10-12 | 2022-03-31 |
| Impact of Psychoeducational Video on Adjustment to Open Fracture. Video Viewing - Major Trauma | Not applicable | Terminated | Oxford University Hospitals NHS Trust | 22 | 2020-12-03 | 2023-01-13 |
| ErythroPOietin Alfa to Prevent Mortality and Reduce Severe Disability in Critically Ill TRAUMA Patients Epoetin Alfa 40000 UNT/ML, Sodium Chloride 0.9% - Trauma, Traumatic Injury | Phase 3 | Recruiting | Australian and New Zealand Intensive Care Research Centre | 2500 | 2020-11-09 | 2025-07-16 |
| Effect of Anti-inflammatory and Anti-microbial Co-supplementations in Traumatic ICU Patients at High Risk of Sepsis oral lactobacillus probiotics plus intramuscular cholecalciferol, intravenous vitamin C plus thiamine - Major Trauma, Sepsis | Not applicable | Completed | Mansoura University | 112 | 2020-02-18 | 2021-10-11 |
| Brain Oxygenation During Prehospital Anesthesia: an Observational Study Cerebral near-infrared spectroscopy - Critically Ill, Major Trauma | Unknown | Helsinki University Central Hospital | 1300 | 2019-11-18 | 2022-10-28 | |
| Markers of Tissue Injury and Rhabdomyolysis in Patients With Major Trauma Laboratory analysis - upon admission, Laboratory analysis - 24 hours after injury - Tissue Injury, Major Trauma | Completed | University Hospital Ostrava | 150 | 2019-06-15 | 2024-03-20 | |
| Skeletal Muscle Wasting and Renal Dysfunction After Critical Illness Trauma - Outcomes Study Exposure of significant critical illness - Critical Illness, Acute Kidney Injury | Completed | Queen Mary University of London | 40 | 2018-12-19 | 2022-09-14 | |
| Vitamin D for Critically Traumatic Patients Vitamin D, Placebo - Vitamin D Deficiency, Major Trauma | Not applicable | Unknown | National Taiwan University Hospital | 100 | 2018-05-01 | 2024-08-16 |
| Experiences of Visitors to a Regional Major Trauma Intensive Care Unit Qualitative interviews and questionnaire survey - Major Trauma | Completed | Kingston University | 57 | 2017-11-16 | 2018-10-09 | |
| Structured Trauma Quality Improvement Meetings at Four Trauma Centres in India TQIM checklist - Major Trauma, Injuries Major | Not applicable | Completed | Dr Gerard O'Reilly | 1500 | 2017-01-01 | 2019-11-27 |
| Pre-hospital Notification of Injured Patients Presenting to Trauma Centres in India Pre-hospital notification - Major Trauma | Unknown | Teresa Howard | 500 | 2016-03-01 | 2016-08-24 | |
| Severe Trauma Registry in Tarragona Major Trauma, Traumatic Brain Injury | Completed | Hospital Universitari Joan XXIII de Tarragona. | 1000 | 2015-01-01 | 2023-08-23 | |
| Hyperfibrinogenemia After Major Trauma Blood samples - Major Trauma | Not applicable | Unknown | University Hospital, Montpellier | 150 | 2014-09-01 | 2015-07-28 |
| Succinylcholine vs Rocuronium for Prehospital Emergency Intubation Succinylcholine : 1mg/kg, Rocuronium : 1.2 mg/kg - Coma, Major Trauma | Phase 3 | Completed | Centre Hospitalier Universitaire de la Réunion | 1321 | 2013-12-01 | 2017-12-15 |
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Wounds and Injuries (9) · Brain Injuries, Traumatic (3) · Emergencies (3) · Shock (3) · Acute Kidney Injury (2) · Coma (2) · Critical Illness (2) · Dyspnea (2) · Hemorrhage (2) · Hemostatic Disorders (2) · Multiple Trauma (2) · Sepsis (2) · Burns (1) · Conversion Disorder (1) · Fractures, Open (1)
Pathological Conditions, Signs and Symptoms (11) · Pathologic Processes (9) · Nervous System Diseases (6) · Cardiovascular Diseases (4) · Disease Attributes (4) · Neurologic Manifestations (4) · Signs and Symptoms (4) · Brain Diseases (3) · Brain Injuries (3) · Central Nervous System Diseases (3) · Craniocerebral Trauma (3) · Trauma, Nervous System (3) · Vascular Diseases (3) · Consciousness Disorders (2) · Female Urogenital Diseases (2)
Blood Specimen Collection (1) · Electroacupuncture (1) · Epoetin Alfa (1) · Factor IX (1) · Fibrinogen (1) · Rocuronium (1) · Sodium Chloride (1) · Standard of Care (1) · Succinylcholine (1) · Thiamine (1) · Vascular Access Devices (1) · Vasoconstrictor Agents (1) · Vitamin D (1)
National Taiwan University Hospital (2) · Australian and New Zealand Intensive Care Research Centre (1) · Centre Hospitalier Universitaire de la Réunion (1) · Chang Gung Memorial Hospital (1) · Dr Gerard O'Reilly (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Helsinki University Central Hospital (1) · Henri Mondor University Hospital (1) · Hospital Universitari Joan XXIII de Tarragona. (1) · Hossam Abdel Rahman Ahmed Ismail (1) · Kantonsspital Aarau (1) · Kingston University (1) · Kocaeli City Hospital (1) · Manchester University NHS Foundation Trust (1) · Mansoura University (1)
United Kingdom (4) · France (3) · Taiwan (3) · Finland (2) · India (2) · Switzerland (2) · Australia (1) · Austria (1) · Belgium (1) · Canada (1) · Czechia (1) · Egypt (1) · Germany (1) · Ireland (1) · New Zealand (1)
Mark C Fitzgerald, MBBS, MD (2) · Alexandre Mebazaa, MD, PhD (1) · Associate Professor Craig French (1) · Chun-Ting Liu, Dr. (1) · Claudia dos Santos, MD, PhD (1) · Gerard Moreno, PhD (1) · Jason Wong, MD (1) · Jouni Nurmi, MD, PhD (1) · Maha Ahmed Abozeid, MD (1) · May Quarmby, D Clin (1) · Michal Frelich, MD,PhD (1) · Professor Alistair Nichol (1) · Stefan T Kulnik, PhD (1) · Thomas Corbett, MSc (1)
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