104 completed, 44 unknown, 23 not yet recruiting, 21 recruiting. 133 Not applicable, 14 Phase 4, 8 Phase 3, 5 Phase 1, 4 Phase 2.
Follow Lumbar Disc Herniation: new trials by email Literature Review of Lumbar Disc Herniation trials Research Report on Lumbar Disc Herniation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Randomized Evaluation of Lumbar Injection Effectiveness and Function Triojection® System, Selective Nerve Root Block (SNRB) - Lumbar Radiculopathy, Lumbar Disc Herniation | Not applicable | Not yet recruiting | SpinaFX Medical Inc. | 300 | 2027-01-15 | 2026-10-07 |
| Comparing Three Epidural Steroid Injection Approaches for Lumbar Radicular Pain High-Volume Parasagittal Interlaminar Epidural Steroid Injection, Low-Volume Parasagittal Interlaminar Epidural Steroid Injection, Transforaminal epidural steroid injection - Lumbar Disc Herniation, Lumbosacral Radiculopathy | Phase 4 | Not yet recruiting | Benha University | 99 | 2026-10-01 | 2026-09-14 |
| Pulmonary Mechanics and Cerebral Oxygenation During Prone Lumbar Disc Surgery Prone Positioning - Lumbar Disc Herniation, Respiratory Mechanics | Recruiting | Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital | 100 | 2026-09-09 | 2026-10-09 | |
| Lower Back Muscle Size and Recovery After Lumbar Disc Herniation Surgery Preoperative Psoas and Multifidus Muscle Measurements - Postoperative Recovery, Lumbar Disc Herniation | Not yet recruiting | Fatih Sultan Mehmet Training and Research Hospital | 100 | 2026-09-01 | 2026-08-17 | |
| Biologic Injection For Adults With Lumbar Disc Herniation Bone Marrow Aspirate Concentrate (BMAC) - Degenerative Disc Disease, DDD | Not applicable | Recruiting | Weill Medical College of Cornell University | 90 | 2026-08-30 | 2026-07-29 |
| Comparison of 5 vs 8 cmH₂O PEEP on Respiratory Mechanics in Prone Lumbar Surgery Mechanical Ventilation (PEEP) - Lumbar Disc Herniation, Spinal Surgery | Not applicable | Not yet recruiting | Harran University | 60 | 2026-08-15 | 2026-08-11 |
| Comparison of TLIP Block and QIP Block for Postoperative Analgesia After Lumbar Spine Surgery Thoracolumbar Interfascial Plane (TLIP) Block of bupivacaine, Quadratus Lumborum-Iliac Plane (QIP) Block - Lumbar Disc Herniation, Postoperative Pain | Not yet recruiting | Vezirköprü State Hospital | 60 | 2026-08-15 | 2026-08-06 | |
| Validation of a Methodology Using Isometric Dynamometer for Ankle STrength Assessment to Quantify LDH-induced Paresis Strength test validity and reliability - Paresis, Lumbar Disc Herniation | Not applicable | Enrolling by invitation | Helsinki University Central Hospital | 70 | 2026-08-10 | 2026-08-13 |
| Magnesium Sulfate for Prevention of Emergence Agitation in Lumbar Disc Surgery Magnesium Sulfate Infusion, 0.9% Saline Infusion - Lumbar Disc Herniation, Emergence Agitation | Not yet recruiting | Ondokuz Mayıs University | 70 | 2026-07-05 | 2026-06-25 | |
| Brain Connectomic Mechanisms of Spinal Manipulative Therapy on LDH Analgesia Based on Multimodal MRI Active Lever Positioning Manipulation, Sham Lever Positioning Manipulation - Lumbar Disc Herniation | Not applicable | Not yet recruiting | The Third Affiliated hospital of Zhejiang Chinese Medical University | 126 | 2026-07-01 | 2026-07-27 |
| Comparison Of Early Mobilization And Electrical Stimulation On Functional Recovery After Lumbar Disc Herniation Surgery Early Mobilization Program, Electrical Stimulation (NMES/TENS) - Lumbar Disc Herniation, Low Back Pain | Not applicable | Not yet recruiting | Istanbul Medipol University Hospital | 60 | 2026-06-30 | 2026-06-16 |
| Acute Effects of Neurodynamics on Strength and Endurance in Athletes Sciatic Slider, Sciatic Tensioner, Mechanically loaded neurodynamic sciatic floss - Sciatic Leg Pain, Hamstring Muscle Tightness | Not applicable | Recruiting | High Point University | 45 | 2026-06-15 | 2026-07-22 |
| Evaluation of the Effectiveness of Physical Therapy for Low Back Pain According to Magnetic Resonance Imaging Findings Standard Physical Therapy Program - Low Back Pain, Physical Therapy | Not applicable | Not yet recruiting | Bahçeşehir University | 120 | 2026-06-10 | 2026-06-16 |
| Electroacupuncture for Insomnia in Patients With Chronic Sciatica Due to Lumbar Disc Herniation: a Randomized Controlled Trial Electroacupuncture, Sham electroacupuncture - Sciatica, Lumbar Disc Herniation | Not applicable | Not yet recruiting | Shanghai Yueyang Integrated Medicine Hospital | 114 | 2026-05-01 | 2026-05-08 |
| Daytime vs Evening Rehabilitation in Lumbar Disc Herniation Patients at High Risk for Obstructive Sleep Apnea Physiotherapy and Exercise Program - Lumbar Disc Herniation, Obstructive Sleep Apnea Risk Management | Not applicable | Not yet recruiting | Mardin Artuklu University | 60 | 2026-04-10 | 2026-04-13 |
| Clinical and MRI Findings in Lumbar Disc Disease Lumbar Disc Disease, Low Back Pain | Not yet recruiting | Assiut University | 96 | 2026-04-01 | 2026-04-08 | |
| PLDD With or Without Transforaminal Epidural Steroid Injection in Lumbar Disc Herniation Percutaneous Laser Disc Decompression (PLDD), Transforaminal Anterior Epidural Steroid Injection - Lumbar Disc Herniation, Lumbar Radiculopathy | Not yet recruiting | Mersin University | 88 | 2026-03-01 | 2026-02-10 | |
| Comparison of Virtual Reality-Based and Routine Preoperative Education on Surgical Anxiety and Salivary Cortisol Virtual Reality-Based Preoperative Education, Routine Preoperative Education - Lumbar Disc Herniation, Preoperative Anxiety | Not applicable | Not yet recruiting | Bezmialem Vakif University | 56 | 2026-02-27 | 2026-03-02 |
| The Role of Temporal Changes in Pain Response After Transforaminal Epidural Steroid Injection on Treatment Success Transforaminal epidural steroid injection - Lumbar Disc Herniation, Lumbar Radiculopathy | Not yet recruiting | Marmara University | 120 | 2026-02-15 | 2026-01-26 | |
| Effect of Irrigation Pressure on Postoperative Complications and Surgical Field Clarity in Unilateral Biportal Endoscopic Surgery Unilateral Biportal Endoscopic Surgery - Lumbar Disc Herniation, Lumbar Spinal Stenosis | Not applicable | Recruiting | Fan Zhang | 80 | 2026-02-05 | 2026-09-23 |
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Intervertebral Disc Displacement (213) · Spinal Stenosis (32) · Low Back Pain (28) · Radiculopathy (28) · Intervertebral Disc Degeneration (14) · Pain (14) · Sciatica (12) · Spondylolisthesis (12) · Intervertebral disc disease (11) · Pain, Postoperative (11) · Hernia (7) · Motor Activity (4) · Spinal Diseases (4) · Patient Satisfaction (3) · Sleep Initiation and Maintenance Disorders (3)
Pathological Conditions, Signs and Symptoms (213) · Bone Diseases (212) · Musculoskeletal Diseases (212) · Pathological Conditions, Anatomical (212) · Spinal Diseases (209) · Hernia (206) · Signs and Symptoms (71) · Neurologic Manifestations (68) · Pain (49) · Nervous System Diseases (44) · Neuromuscular Diseases (35) · Peripheral Nervous System Diseases (35) · Back Pain (29) · Pathologic Processes (18) · Postoperative Complications (15)
Physical Therapy Modalities (5) · Bupivacaine (4) · Exercise (4) · Acetaminophen (3) · Diskectomy (3) · Electroacupuncture (3) · Ropivacaine (3) · Acupuncture Therapy (2) · Control Groups (2) · Dexamethasone (2) · Lidocaine (2) · Magnetic Resonance Spectroscopy (2) · Manipulation, Spinal (2) · Sensitivity Training Groups (2) · Sodium Chloride (2)
Medipol University (8) · Intrinsic Therapeutics (7) · Marmara University (7) · Peking University Third Hospital (6) · Bezmialem Vakif University (5) · Assiut University (4) · Jaseng Medical Foundation (4) · Riphah International University (4) · Ankara City Hospital Bilkent (3) · Aqua Medical Services (Pvt) Ltd (3) · Hacettepe University (3) · Istanbul Medipol University Hospital (3) · The Third Affiliated hospital of Zhejiang Chinese Medical University (3) · Xuanwu Hospital, Beijing (3) · Akdeniz University (2)
Turkey (Türkiye) (61) · China (36) · United States (21) · Egypt (9) · Pakistan (8) · South Korea (8) · Switzerland (5) · France (4) · Germany (4) · Netherlands (4) · Belgium (3) · Austria (2) · Cyprus (2) · Denmark (2) · Greece (2)
Byung-Kwan Seo, PhD., KMD (2) · David H Kim, MD (2) · Abdul Ghaffor Sajjad, PhD (1) · Abdul Ghafoor Sajjad, MSPT (1) · Abdul Ghafoor Sajjad, PhD* (1) · Affan Iqbal, Phd* (1) · Ahmed Elsayed Abo Kresha, Assistant Prof. (1) · Alberto Gotfryd, PhD (1) · Alexander Chan, MD (1) · Alp Esrefoglu, PT (1) · Ammar Javed, MS OMPT* (1) · Andrew J Haig, MD (1) · Asghar Khan, DCS-PT (1)
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