726 completed, 350 unknown, 204 recruiting, 91 terminated. 1597 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 1597 | Completed 726, Unknown 350, Recruiting 204, Terminated 91, Not yet recruiting 86, Active not recruiting 68, Withdrawn 44, Enrolling by invitation 22, Suspended 6 |
Follow Leg Injuries: new trials by email Literature Review of Leg Injuries trials Research Report on Leg Injuries
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Reducing Disparities in Knee Arthroscopy for Adolescents Educational program and patient navigator - Knee Injury, ACL Injury | Not applicable | Not yet recruiting | Ann & Robert H Lurie Children's Hospital of Chicago | 80 | 2027-10-01 | 2026-06-18 |
| Intraoperative Analysis of Knee Kinematics During ACL Reconstruction - an Exploratory Study Knee Cinematics - ACL - Anterior Cruciate Ligament Rupture | Not applicable | Not yet recruiting | GCS Ramsay Santé pour l'Enseignement et la Recherche | 30 | 2027-07-01 | 2026-06-18 |
| Exercise Program for ITB Syndrome Individualized Exercise Program, Standard Physical Therapy - Iliotibial Band Syndrome | Not applicable | Not yet recruiting | NYU Langone Health | 100 | 2027-03-01 | 2026-08-07 |
| Relationship Between Anesthetic Regimen and Bone Cement Implantation Syndrome (BCIS) Administration of general anaesthesia, Neuraxial Analgesia - Bone Cement Implantation Syndrome | Not applicable | Enrolling by invitation | Johns Hopkins University | 24 | 2027-01-10 | 2026-07-21 |
| Study of the AxisBoard Single-Leg Balance Board in Adults With Lateral Ankle Sprain AxisBoard Single-Leg Balance Board - Ankle Sprains, Lateral Ankle Sprain | Not applicable | Not yet recruiting | DITU Inc. | 80 | 2027-01-04 | 2026-10-06 |
| Outpatient Floor Pedal Bike Utilization Floor Pedal Bike with Guided Instructions for Home - Femur Fracture, Tibia Fracture | Not applicable | Not yet recruiting | Wake Forest University Health Sciences | 20 | 2027-01-01 | 2026-10-26 |
| Accelerated Flap Coverage Versus Standard Timing in the Treatment of Severe Lower Extremity Musculoskeletal Injuries Accelerated Flap Coverage Surgery, Standard of Care Flap Timing - Open Tibia Fracture, Open Dislocation of Ankle | Not applicable | Not yet recruiting | Johns Hopkins University | 356 | 2027-01-01 | 2026-09-18 |
| Low-cost Negative Pressure Wound Therapy vs Standard Dressings for Gustilo IIIb Tibial Fractures (Bukavu Pilot RCT) intervention2: standard wound dressing, Intervention1: Low-cost NPWT - Open Tibia Fracture | Not applicable | Not yet recruiting | Université Catholique de Bukavu | 66 | 2027-01-01 | 2026-08-27 |
| Personalized Weight-Bearing With Smart Crutch Tips After Surgery for Tibial Plateau Fractures Crutch Tip Biofeedback System, Individualized FEA-Guided Postoperative Weight-Bearing, Usual-Care Postoperative Weight-Bearing - Tibial Plateau Fracture | Not applicable | Not yet recruiting | Comeback Mobility Inc | 86 | 2026-11-15 | 2026-10-27 |
| SharkScrew ACL RCT ACL Reconstruction with a Biocomposite Screw, ACL Reconstruction using a PEEK Screw, ACL Reconstruction using an Allograft Screw - ACL - Anterior Cruciate Ligament Rupture | Not applicable | Not yet recruiting | Austrian Workers Compensation Board Styria | 33 | 2026-11-01 | 2026-10-05 |
| Magnesium Alloy Scaffold With Controlled Degradation for Periarticular Bone Defects Magnesium Alloy Scaffold, Calcium Sulfate Bone Graft Substitute - Periarticular Bone Defect, Proximal Humerus Fracture | Not applicable | Not yet recruiting | Peking University Third Hospital | 120 | 2026-11-01 | 2026-10-30 |
| Clinical and Biological Outcomes of BioBrace-Augmented ACL Reconstruction BioBrace® Reinforced BioInductive Implant - Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture | Not applicable | Not yet recruiting | Yonsei University | 30 | 2026-11-01 | 2026-10-30 |
| Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Postoperative Recovery Quality in Patients Undergoing Anterior Cruciate Ligament Reconstruction Experimental-Active taVNS, Sham transcutaneous auricular vagus nerve stimulation - Anterior Cruciate Ligament Injuries, Recovery Quality | Not applicable | Not yet recruiting | Peking University Third Hospital | 144 | 2026-10-28 | 2026-10-29 |
| Monitored Anesthesia Care and Soft Tissue Infiltration With Local Anesthesia Feasibility Trial Monitored Anesthesia Care (MAC), Soft Tissue Infiltration with Local Anesthetic (STILA), General Anesthesia - Hip Fracture Surgeries, Intertrochanteric Fracture | Not applicable | Recruiting | NYU Langone Health | 140 | 2026-10-27 | 2026-10-29 |
| Trochanteric Bursa Repair and Lateral Hip Pain After Hemiarthroplasty for Femoral Neck Fracture Trochanteric Bursa Repair, Trochanteric Bursa Left Unrepaired - Femoral Neck Fracture | Not applicable | Not yet recruiting | Osman Sarıyar | 102 | 2026-10-12 | 2026-10-16 |
| Description of Return to Sport in Amateur Athletes Who Underwent Several Functional Tests (K-STARTS, Vertical Jumps and Soleus Muscle Strength) After Initial ACL Reconstruction Physical tests - ACL - Anterior Cruciate Ligament Rupture | Not applicable | Not yet recruiting | GCS Ramsay Santé pour l'Enseignement et la Recherche | 230 | 2026-10-01 | 2026-08-20 |
| Efficacy of Oral Nutritional Supplement in Femoral Neck Fracture Patients Undergoing Hip Arthroplasty Oral nutritional supplementation - Femoral Neck Fractures, Geriatric Hip Fracture | Not applicable | Not yet recruiting | Thammasat University | 60 | 2026-10-01 | 2026-08-21 |
| Supporting Athletes' Return to Sports After ACL Reconstruction: A Study of a Psychological Readiness Program Unbroken Comeback - Anterior Cruciate Ligament Reconstruction, Anterior Cruciate Ligament Injuries | Not applicable | Not yet recruiting | Inova Health Care Services | 30 | 2026-10-01 | 2026-10-15 |
| Correlation Study Between the Classification of Arthrogenic Motor Inhibition (AMI) and Clinical Assessment After ACL Rupture Clinical testing - ACL - Anterior Cruciate Ligament Rupture | Not applicable | Not yet recruiting | GCS Ramsay Santé pour l'Enseignement et la Recherche | 90 | 2026-10-01 | 2026-08-20 |
| AI-Supported Physiotherapy After Hip Fracture in Frail Older Adults Conventional hospital physiotherapy, Automated motivational support and movement-capture system - Hip Fractures, Frailty | Not applicable | Not yet recruiting | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal | 48 | 2026-10-01 | 2026-10-05 |
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Anterior Cruciate Ligament Injuries (407) · Hip Fractures (386) · Ankle Injuries (212) · Knee Injuries (148) · Ankle Fractures (121) · Femoral Neck Fractures (111) · Femoral Fractures (95) · Tibial Fractures (72) · Pain, Postoperative (52) · Fractures, Bone (47) · Wounds and Injuries (39) · Foot Injuries (38) · Pain (37) · Osteoarthritis, Knee (33)
Wounds and Injuries (1558) · Fractures, Bone (735) · Femoral Fractures (481) · Hip Injuries (476) · Knee Injuries (440) · Pathological Conditions, Signs and Symptoms (255) · Musculoskeletal Diseases (188) · Signs and Symptoms (170) · Neurologic Manifestations (159) · Pathologic Processes (157) · Joint Diseases (123) · Ankle Injuries (104) · Hip Fractures (98) · Nervous System Diseases (97)
Fracture Fixation, Internal (28) · Physical Therapy Modalities (25) · Bupivacaine (22) · Exercise (22) · Standard of Care (22) · Blood Flow Restriction Therapy (20) · Control Groups (20) · Ropivacaine (16) · Anesthesia, Spinal (15) · Anterior Cruciate Ligament Reconstruction (14) · Surgical Procedures, Operative (14) · Arthroplasty, Replacement, Hip (12) · Resistance Training (12) · Anesthesia, General (11) · Fracture Fixation, Intramedullary (11)
Peking University Third Hospital (27) · Riphah International University (22) · Cairo University (16) · Assiut University (14) · Chang Gung Memorial Hospital (14) · Ain Shams University (12) · Mayo Clinic (12) · University of British Columbia (11) · University of Virginia (11) · GCS Ramsay Santé pour l'Enseignement et la Recherche (10) · Istituto Ortopedico Rizzoli (10) · NYU Langone Health (10) · Johns Hopkins University (9) · Stanford University (9) · University of Michigan (9)
United States (384) · Turkey (Türkiye) (113) · Canada (90) · China (90) · Egypt (74) · France (64) · Spain (64) · Norway (53) · Pakistan (53) · Denmark (51) · United Kingdom (45) · Italy (38) · Sweden (31) · Belgium (29) · Brazil (29)
Gregory D Myer, PhD (4) · Jason M Wilken, PT, PhD (4) · David A Volgas, MD (3) · Jay Hertel, PhD (3) · Li Cao (3) · Robert F LaPrade, MD, PhD (3) · Aaron Nauth, MD, FRCSC (2) · Aaron Young, Ph.D. (2) · Adam Anz, MD (2) · Adam Weaver, PT, DPT (2) · Alexandra Papaioannou, MD, MSc (2) · Amir Khoshbin, MD (2) · Brian Pietrosimone, PhD (2) · Chandramouli Krishnan, PT, PhD (2)
PMID 33238043, PMID 36070134, PMID 34766330, PMID 36197809, PMID 15902321, PMID 16309613, PMID 19926634, PMID 20236640, PMID 22035956, PMID 22610971, PMID 25068412, PMID 26920430, PMID 29789919, PMID 30063657, PMID 32298131, PMID 33913035, PMID 34145009, PMID 34988237, PMID 35988569, PMID 37715173, PMID 10053175, PMID 10333917, PMID 10505128, PMID 10551571, PMID 10565645, PMID 10613941, PMID 10778794, PMID 10818378, PMID 10898201, PMID 10898394, PMID 10916593, PMID 10959926, PMID 10994917, PMID 10999422, PMID 11126507, PMID 11129764, PMID 11380742, PMID 11386929, PMID 11402405, PMID 11665744, PMID 11686947, PMID 11929206, PMID 11949665, PMID 12046489, PMID 12143985, PMID 12560416, PMID 12689785, PMID 12772137, PMID 12776983, PMID 12777366
2018 (2), 2019 (2), 2023 (2), 2025 (2), R01AR055563 (2), R21AR082643 (2), 1UG3AR085896 (1), 2009 (1), 2016 (1), 2017 (1), K01AR082421 (1), K08AR053152 (1), K23AR079056 (1), K23AR084596 (1), K76AG057020 (1)