19 completed, 8 unknown, 6 recruiting, 1 active not recruiting. 7 Not applicable, 7 Phase 3, 2 Phase 2, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 5, Unknown 2 |
| Phase 3 | 7 | Completed 3, Recruiting 3, Terminated 1 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
| Phase 4 | 2 | Completed 1, Recruiting 1 |
Follow Left Ventricular Systolic Dysfunction: new trials by email Literature Review of Left Ventricular Systolic Dysfunction trials Research Report on Left Ventricular Systolic Dysfunction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Preoperative Gastric Ultrasound and Left Ventricular Function in Coronary Artery Bypass Surgery Gastric Ultrasonography - Coronary Artery Disease, Left Ventricular Systolic Dysfunction | Recruiting | Adiyaman University | 50 | 2026-11-04 | 2026-11-06 | |
| A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction Finerenone (Kerendia, BAY94-8862) - Left Ventricular Systolic Dysfunction, Heart Failure (Pediatric) | Phase 3 | Recruiting | Bayer | 117 | 2026-06-01 | 2026-10-27 |
| A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction Finerenone (Kerendia, BAY94-8862), Placebo - Left Ventricular Systolic Dysfunction, Heart Failure (Pediatric) | Phase 3 | Recruiting | Bayer | 111 | 2025-11-19 | 2026-10-15 |
| Multimodality Evaluation of Left Ventricular Remodeling In Mitral Regurgitation: A Pilot Study Cardiac MRI - Left Ventricular Systolic Dysfunction | Recruiting | Mayo Clinic | 30 | 2025-01-20 | 2026-03-03 | |
| Effect of Oral sucRosomIal Iron on exerciSE Capacity and Quality of Life in Patients With Heart Failure Sucrosomial iron, Placebo - Chronic Heart Failure, Iron-deficiency | Phase 4 | Recruiting | Raffaele De Caterina | 60 | 2024-03-14 | 2025-10-01 |
| AI-ECG Screening for Left Ventricular Systolic Dysfunction AI algorithm conducted on 12-lead ECG and transthoracic echocardiography - Left Ventricular Systolic Dysfunction | Unknown | Seoul National University Hospital | 1530 | 2024-02-01 | 2024-02-05 | |
| Early Evaluation of Left Ventricular Systolic Function Impairment in Patients With Chronic Kidney Disease by Multimodal Ultrasonography Chronic Kidney Diseases, Left Ventricular Systolic Dysfunction | Unknown | Fifth Affiliated Hospital, Sun Yat-Sen University | 500 | 2023-10-01 | 2024-04-11 | |
| The SMART-LV Pilot Study AI-ECG - Left Ventricular Systolic Dysfunction | Not applicable | Completed | Yale University | 10 | 2023-09-13 | 2024-05-24 |
| Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036) Vericiguat tablet, Vericiguat suspension, Placebo tablet - Heart Failure, Left Ventricular Systolic Dysfunction | Phase 2 / Phase 3 | Recruiting | Merck Sharp & Dohme LLC | 342 | 2023-05-31 | 2026-11-10 |
| A Study to Evaluate Accuracy and Validity of the "Chang Gung" Ventricular Systolic Dysfunction Screening Software "Chang Gung" Ventricular Systolic Dysfunction Screening Software - Left Ventricular Systolic Dysfunction | Not applicable | Completed | Chang Gung Memorial Hospital | 1172 | 2023-04-15 | 2023-10-12 |
| The Effect of Early Administration of Dapagliflozin in STEMI Patients With LV Systolic Dysfunction Dapagliflozin 10Mg Tab, Placebo - STEMI - ST Elevation Myocardial Infarction, Left Ventricular Systolic Dysfunction | Not applicable | Unknown | Assiut University | 300 | 2021-12-01 | 2021-09-16 |
| Simplified Assessment of Left Ventricular Systolic Function in Septic Shock Patients Left Ventricular Systolic Dysfunction, Septic Shock | Completed | Centre Hospitalier Universitaire, Amiens | 80 | 2021-09-20 | 2026-06-24 | |
| Hyperkalaemia and Its Impact on Therapy with RAASi Hyperkalaemia, Heart Failure with Reduced Ejection Fraction | Completed | Portsmouth Hospitals NHS Trust | 651 | 2021-07-12 | 2024-11-14 | |
| The Relationship Between Inflammatory ARTritis and CArdiac DIseAse Inflammatory Arthritis, Rheumatoid Arthritis | Active not recruiting | University Hospital, Gentofte, Copenhagen | 1285 | 2021-01-01 | 2024-02-28 | |
| Ertugliflozin for Functional Mitral Regurgitation Ertugliflozin, Placebo - Mitral Valve Insufficiency, Left Ventricular Systolic Dysfunction | Phase 3 | Completed | Asan Medical Center | 128 | 2020-11-04 | 2025-01-06 |
| Adjunctive DobutAmine in sePtic Cardiomyopathy With Tissue Hypoperfusion Placebos, Dobutamine - Sepsis, Cardiomyopathies | Phase 3 | Completed | University Hospital, Limoges | 136 | 2020-09-20 | 2025-11-21 |
| Multicenter Normal Reference Study of Tissue Motion Tracking of Mitral Annular Displacement(TMAD) Echocardiography - Left Ventricular Systolic Dysfunction, Healthy Volunteers | Unknown | Weidong Ren | 2400 | 2020-06-01 | 2020-05-22 | |
| Cardiovascular Magnetic Resonance GUIDEd Insertion of Implantable Cardiac Defibrillator in Dilated CardioMyopathy ICD, ILR - Dilated Cardiomyopathy, Left Ventricular Systolic Dysfunction | Not applicable | Unknown | Flinders University | 1880 | 2020-06-01 | 2019-06-21 |
| Mechanisms and Innovations in Cardiac Resynchronisation Therapy His-bundle pacing. - Heart Failure, Left Ventricular Systolic Dysfunction | Not applicable | Completed | Imperial College London | 47 | 2019-10-15 | 2023-03-22 |
| Adherence to Cied Implantation Guidelines and Cardiac Rehabilitation Left Ventricular Systolic Dysfunction, Myocardial Infarction | Completed | Istituti Clinici Scientifici Maugeri SpA | 488 | 2019-09-15 | 2025-01-29 |
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Ventricular Dysfunction, Left (36) · Heart Failure (14) · Coronary Artery Disease (3) · Mitral Valve Insufficiency (3) · Myocardial Infarction (3) · Death, Sudden, Cardiac (2) · Heart Failure, Systolic (2) · Iron Deficiencies (2) · Myocardial Ischemia (2) · ST Elevation Myocardial Infarction (2) · Shock, Septic (2) · Anemia, Iron-Deficiency (1) · Arthritis (1) · Arthritis, Rheumatoid (1) · Axial Spondyloarthritis (1)
Ventricular Dysfunction (36) · Cardiovascular Diseases (35) · Heart Diseases (35) · Pathological Conditions, Signs and Symptoms (12) · Pathologic Processes (11) · Vascular Diseases (6) · Infarction (4) · Ischemia (4) · Metabolic Diseases (4) · Myocardial Ischemia (4) · Necrosis (4) · Nutritional and Metabolic Diseases (4) · Arterial Occlusive Diseases (3) · Arteriosclerosis (3) · Coronary Disease (3)
finerenone (2) · 2'-deoxythymidylyl-(3'-5')-2'-deoxyadenosine (1) · Adrenergic beta-Antagonists (1) · Angiotensin Receptor Antagonists (1) · Angiotensin-Converting Enzyme Inhibitors (1) · Aspirin (1) · Cardiac Resynchronization Therapy (1) · Dobutamine (1) · Echocardiography (1) · Echocardiography, Transesophageal (1) · Hydroxymethylglutaryl-CoA Reductase Inhibitors (1) · Linagliptin (1) · Mineralocorticoid Receptor Antagonists (1) · Mitral Valve Annuloplasty (1) · Ticagrelor (1)
Bayer (2) · Flinders University (2) · Heart Care Foundation (2) · Imperial College London (2) · Adiyaman University (1) · Asan Medical Center (1) · Assiut University (1) · Centre Hospitalier Universitaire, Amiens (1) · Chang Gung Memorial Hospital (1) · Corewell Health East (1) · Cytokinetics (1) · Fifth Affiliated Hospital, Sun Yat-Sen University (1) · Gianluca Pontone, MD, PhD (1) · Institut für Pharmakologie und Präventive Medizin (1) · Istituti Clinici Scientifici Maugeri SpA (1)
United Kingdom (11) · United States (10) · Italy (9) · Germany (7) · Belgium (5) · Canada (5) · Hungary (4) · Poland (4) · South Korea (4) · Sweden (4) · Turkey (Türkiye) (4) · Australia (3) · Brazil (3) · Bulgaria (3) · Czechia (3)
Joseph B Selvanayagam, MBBS (2) · Alex Bratt, MD (1) · Andrea Igoren Guaricci, MD (1) · Arman Arghami, MD, MPH (1) · Carlo B. Giorda, MD (1) · Chang-Fu Kuo, MD/Ph.D (1) · Erland Erdmann, Prof (1) · Evaldas Girdauskas, MD (1) · Fadi G Hage, MD (1) · Felice Achilli, MD (1) · GD Puri, Prof (1) · Gabriele Masini, MD PhD (1) · Gianluca Pontone, MD (1) · Giulio Pompilio, MD (1)
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