8 completed, 6 recruiting, 6 unknown, 3 active not recruiting. 13 Not applicable, 4 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 13 | Completed 3, Recruiting 3, Unknown 3, Active not recruiting 2, Not yet recruiting 1, Terminated 1 |
| Phase 4 | 4 | Completed 1, Recruiting 1, Unknown 1, Withdrawn 1 |
Follow Klippel-Feil Syndrome: new trials by email Literature Review of Klippel-Feil Syndrome trials Research Report on Klippel-Feil Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of the Safety and Effectiveness of the CORUS™ Posterior Cervical Stabilization System 3D (PCSS 3D) for the Treatment of 2-level Cervical Degenerative Disease Circumferential Cervical Fusion (CCF), Anterior Cervical Discectomy and Fusion - Degenerative Disc Disease(DDD) | Not applicable | Not yet recruiting | Providence Medical Technology, Inc. | 225 | 2026-06-30 | 2026-07-23 |
| Post-market Observational Clinical Study With the CE-marked Implantable Class IIb Medical Device "ITC CERVICAL" Cervical Disc Degenerative Disorder, Cervical Fusion | Completed | MT Ortho s.r.l. | 32 | 2026-05-01 | 2026-07-28 | |
| Opioid Sparing Effect of an ISP Nerve Block on Post-Op Pain Control in Posterior Cervical Spine Surgery Inter-semispinalis Plane Block, Opioids - Pain, Postoperative | Not applicable | Recruiting | Stony Brook University | 60 | 2025-02-21 | 2026-04-29 |
| Multifidus Cervicis Plane Block Vs. Sham Block For Posterior Cervical Spine Fusion Surgery Bupivacaine Hcl 0.25% Inj, Normal saline - Cervical Spine Fusion | Phase 4 | Recruiting | Hartford Hospital | 38 | 2023-12-12 | 2025-09-05 |
| Navigation Image Accuracy Test in Cervical Spine Surgery Using Anatase Spine Surgery Navigation System Anatase Spine Surgery Navigation System - Cervical Spine Fusion | Not applicable | Unknown | China Medical University Hospital | 8 | 2023-11-01 | 2023-11-07 |
| Pre-Operative Ketamine Infusion for Post Operative Pain Control After Revision Spinal Surgery Ketamine Hydrochloride - Revision Spine Surgery, Fusion of Spine | Phase 4 | Unknown | AXIS Spine Center- a division of Northwest Specialty Hospital | 40 | 2023-09-18 | 2023-10-04 |
| Mehri Turki Webbed Neck Classification Turner Syndrome, Pterygium Colli | Completed | Mohamed Tahar Maamouri University Hospital | 78 | 2023-01-27 | 2024-07-05 | |
| Single Level Anterior Cervical Corpectomy Without Posterior Stabilization anterior cervical corpectomy and fusion - Cervical Spine Fusion | Not applicable | Unknown | Assiut University | 20 | 2022-08-01 | 2022-07-29 |
| Posterior Cervical Fixation Study observational study - Degenerative Disc Disease, Craniocervical Injuries | Enrolling by invitation | NuVasive | 150 | 2022-05-10 | 2025-12-22 | |
| Fusion or no Fusion After Decompression of the Spinal Cord in Patients With Degenerative Cervical Myelopathy Muscle preserving selective laminectomy, Laminectomy with instrumented fusion - Cervical Spondylotic Myelopathy | Not applicable | Recruiting | Uppsala University Hospital | 300 | 2022-02-21 | 2025-04-08 |
| Cervical Arthroplasty Cost Effectiveness Study (CACES) ACDF, ACDA - Radiculopathy, Cervical, Myelopathy Cervical | Not applicable | Recruiting | Valérie Schuermans | 198 | 2022-01-17 | 2024-01-25 |
| Anterior Cervical Disectomy And Fusion Using The Tritanium® C Anterior Cervical Cage For One Or Two-Levels Tritanium C Anterior Cervical Cage - Cervical Disc Herniation, Cervical Disc Degeneration | Not applicable | Active not recruiting | Corewell Health East | 50 | 2021-05-05 | 2026-09-25 |
| Measuring Dysphagia After ACDF Surgery Through A Novel Wearable Sensor Anterior Cervical Discectomy & Fusion, Application of ADAM mechanoacoustic skin sensor - Cervical Spine Fusion | Not applicable | Completed | Northwestern University | 11 | 2021-03-15 | 2025-05-09 |
| Trigger Point Injections in Anterior Cervical Surgery Trigger point injection with bupivacaine, Trigger point injection with normal saline, Lidocaine skin wheal - Myofacial Pain, Pain, Neck | Phase 4 | Completed | George Washington University | 60 | 2020-11-05 | 2026-08-13 |
| Allogeinic Bone Paste Cervical fusion - Cervical Fusion, Cervical Disc Degeneration | Not applicable | Unknown | Biobank | 50 | 2020-09-15 | 2020-10-27 |
| Study of Posterior Cervical Stabilization System (PCSS) as Part of Circumferential Fusion to Treat Multilevel DDD Anterior Cervical Discectomy and Fusion, Posterior Cervical Stabilization System (PCSS) - Degenerative Disc Disease | Not applicable | Active not recruiting | Providence Medical Technology, Inc. | 236 | 2020-03-18 | 2025-10-30 |
| Clinical and Radiological Outcomes of Posterior Cervical Fusion Supplemented With Interfacet Spacers Cervical Interfacet Spacers - Cervical Fusion | Recruiting | Ohio State University | 45 | 2019-09-01 | 2026-10-16 | |
| Finnish Trial on Practices of Anterior Cervical Decompression (FACADE) Comparing Outpatient vs. Inpatient Care Discharge on the day of surgery - Cervical Radiculopathy | Not applicable | Completed | Helsinki University Central Hospital | 104 | 2019-06-12 | 2023-03-23 |
| FUSION EVALUATION AFTER ANTERIOR CERVICAL DISCECTOMY AND FUSION WITH STAND ALONE LOCKING CAGE WITH BLADE HRCC® Cervical Radiculopathy, Cervical Spinal Fusion | Unknown | CHU de Reims | 50 | 2019-01-01 | 2019-05-15 | |
| Airway Management of Pediatric Patients With Klippel-Feil Syndrome Ventilation, Intubation - Klippel-Feil Syndrome | Active not recruiting | Boston Children's Hospital | 300 | 2018-11-01 | 2026-04-22 |
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Radiculopathy (7) · Intervertebral Disc Degeneration (6) · Spinal Cord Diseases (5) · Spondylosis (2) · 3-Methylglutaconic Aciduria, Type V (1) · Achalasia Addisonianism Alacrimia syndrome (1) · Acrodysostosis (1) · Addison Disease (1) · Alagille Syndrome (1) · Alstrom Syndrome (1) · Amnesia, Transient Global (1) · Aniridia (1) · Aniridia and Absent Patella (1) · Aniridia, Partial, with Unilateral Renal Agenesis and Psychomotor Retardation (1)
Bone Diseases (27) · Bone Diseases, Developmental (27) · Congenital Abnormalities (27) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (27) · Dysostoses (27) · Musculoskeletal Abnormalities (27) · Musculoskeletal Diseases (27) · Nervous System Diseases (8) · Neuromuscular Diseases (8) · Peripheral Nervous System Diseases (8) · Spinal Diseases (8) · Central Nervous System Diseases (6) · Pathological Conditions, Signs and Symptoms (5) · Neurologic Manifestations (4) · Signs and Symptoms (4)
Gene Fusion (6) · Bupivacaine (2) · Ketamine (2) · Saline Solution (2) · Analgesics, Opioid (1) · Arthroplasty (1) · Dexamethasone (1) · Epinephrine (1) · Intubation (1) · Laminectomy (1) · Observation (1) · Sodium Chloride (1) · Ventilation (1)
Northwestern University (2) · Providence Medical Technology, Inc. (2) · AXIS Spine Center- a division of Northwest Specialty Hospital (1) · Aesculap AG (1) · Assiut University (1) · Biobank (1) · Boston Children's Hospital (1) · CHU de Reims (1) · China Medical University Hospital (1) · Corewell Health East (1) · George Washington University (1) · Hartford Hospital (1) · Helsinki University Central Hospital (1) · LifeNet Health (1) · MT Ortho s.r.l. (1)
United States (16) · France (2) · Australia (1) · Finland (1) · Germany (1) · Italy (1) · Netherlands (1) · Spain (1) · Sweden (1) · Tunisia (1)
Matt Jenkins (2) · Andrew Grossbach, MD (1) · Anna MacDowall, MD, PhD (1) · Anouk Smeets, MD, PhD, Professor (1) · Bruce E. Mathern, M.D. (1) · Cheng-Di Chiu (1) · Eman Nada, MBBCH (1) · Franklin Lin, M.D. (1) · Imen Mehri Turki (1) · Jad G Khalil, MD (1) · James T Ryaby, PhD (1) · Jessica Jameson, MD (1) · Kimmo Lonnrot, MD, PhD (1) · Kyle Malone, MS (1)
PMID 17544854, PMID 21916134, PMID 24328759, PMID 25360528, PMID 25679233, PMID 26516824, PMID 29318534, PMID 29403245, PMID 31772100, PMID 36028916, PMID 36765352, PMID 39602120