8 completed, 3 unknown, 2 recruiting, 1 active not recruiting. 10 Not applicable, 2 Phase 2, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 6, Unknown 2, Active not recruiting 1, Withdrawn 1 |
| Phase 2 | 2 | Completed 1, Unknown 1 |
| Phase 3 | 1 | Completed 1 |
| Phase 4 | 1 | Terminated 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Wound Healing Following Extraction and Ridge Preservation in Smokers and Non-smokers observational study - Smoking, Cigarette, Alveolar Bone Grafting | Not yet recruiting | Marquette University | 12 | 2026-01-25 | 2026-01-28 | |
| Matrion Decellularized Placental Membrane Versus Conventional Wound Management in Subjects With Diabetic Foot Ulcers Graft Application, Wound Dressing Material - Diabetic Foot Ulcer (DFU), Lower Extremity | Not applicable | Active not recruiting | LifeNet Health | 120 | 2025-06-26 | 2026-09-14 |
| Periodontal Regeneration With Recombinant Human Platelet Derived Growth Factor (rH-PDGF-BB) and Allograft Allograft and rHPDGF-BB, Allograft and Saline solution - Periodontal Diseases | Phase 2 | Unknown | Universidad Autonoma de Nuevo Leon | 30 | 2024-01-10 | 2024-05-01 |
| Decellularized Femoral Artery Allograft (Nexeon AVX) Prospective Registry Nexeon Arterial Venous Allograft - End-Stage Renal Disease | Recruiting | LifeNet Health | 100 | 2023-06-06 | 2026-09-15 | |
| Matrion™ Decellularized Placental Membrane in Subjects With Diabetic Foot Ulcers Matrion, Conventional Care Wound Management - Diabetic Foot, Lower Extremity Wound | Not applicable | Completed | LifeNet Health | 108 | 2022-03-01 | 2025-04-02 |
| Safety, Efficacy, & Use of ViviGen Cellular Bone Matrix Allograft in Orthopaedic Fracture Care Vivigen Cellular Bone Matrix - Fractures, Bone, Nonunion of Fracture | Recruiting | LifeNet Health | 250 | 2021-06-01 | 2026-09-15 | |
| Dermacell ADM Without Basement Membrane Dermacell ADM without basement membrane, FlexHD - Breast Cancer | Not applicable | Unknown | University of Virginia | 120 | 2018-09-01 | 2018-09-12 |
| LifeNet: Extracellular Matrix Graft in Rotator Cuff Repair ArthroFLEX ECM scaffold graft, Control, Alternative Treatment Group - Rotator Cuff Tear | Phase 4 | Terminated | Gregory Gilot | 9 | 2018-07-01 | 2025-06-19 |
| Clinical Effectiveness of DermACELL AWM in Subjects With Chronic Venous Leg Ulcers DermACELL AWM - Venous Leg Ulcer | Not applicable | Completed | LifeNet Health | 100 | 2018-06-25 | 2021-03-18 |
| Comparative Effectiveness of Two Acellular Matrices (Dermacell vs. Integra) for Management of Deep Diabetic Foot Ulcers Dermacell, Integra - Diabetic Foot Ulcer, Deep Diabetic Foot Ulcer | Phase 2 / Phase 3 | Completed | Baylor College of Medicine | 34 | 2018-04-02 | 2023-07-07 |
| DermACELL AWM® in Chronic Wagner Grade 3/4 Diabetic Foot Ulcers DermACELL AWM - Diabetic Foot Ulcer, Lower Extremity Wound | Not applicable | Completed | LifeNet Health | 61 | 2017-01-15 | 2019-09-06 |
| OrACELL™ vs. Connective Tissue in Miller Class 3 Defects OrACELL, Connective Tissue Graft - Gingival Recession | Not applicable | Completed | Texas A&M University | 24 | 2015-03-26 | 2017-07-24 |
| Comparing the Clinical Outcomes of DermACELL® With Integra® Bilayer Wound Matrix DermACELL®, Integra® - Wounds, Chronic Wounds | Not applicable | Unknown | Georgetown University | 53 | 2014-04-18 | 2020-03-11 |
| DermACELL in Subjects With Chronic Wounds of the Lower Extremities DermACELL, GraftJacket, Conventional Care Dressings - Diabetic Foot Ulcer | Not applicable | Completed | LifeNet Health | 202 | 2013-10-01 | 2018-03-14 |
| Allograft Meniscal Arthroplasty for the Treatment of Basal Joint Arthritis of the Thumb Meniscal allograft arthroplasty of the carpometacarpal joint of the thumb - Arthritis | Completed | Corewell Health East | 22 | 2009-03-01 | 2014-07-25 | |
| Safety Study of Preservon-Treated Bone Implants for Cervical Fusion in the Treatment of Cervical Radiculopathy or Myelopathy Anterior Cervical Discectomy and Fusion - Cervical Radiculopathy, Myelopathy | Not applicable | Completed | LifeNet Health | 106 | 2006-09-01 | 2015-04-07 |
| Devitalized Non-valved Pulmonary Artery Allograft Implant for the Repair of Congenital Cardiac Abnormalities Investigational Device, Experimental, Cryopreserved - NA-Study Withdrawn | Not applicable | Withdrawn | LifeNet Health | 2015-04-07 |
Diabetic Foot (5) · Varicose Ulcer (2) · Arthritis (1) · Breast Neoplasms (1) · Cigarette Smoking (1) · Femoral Fractures (1) · Foot Diseases (1) · Foot Ulcer (1) · Fractures, Bone (1) · Fractures, Open (1) · Fractures, Ununited (1) · Gingival Recession (1) · Kidney Failure, Chronic (1) · Klippel-Feil Syndrome (1) · Osteoarthritis (1)
Bandages (1) · Becaplermin (1) · Cryopreservation (1) · FlexHD (1) · Gene Fusion (1) · Observation (1) · Saline Solution (1) · Surgical Procedures, Operative (1) · Transplantation, Homologous (1) · integra artificial skin (1)
United States (14) · Mexico (1)
Bruce E. Mathern, M.D. (1) · Christopher Attinger, MD (1) · Gregory J Gilot, MD (1) · Kimberly Dorsch (1) · Mark Moore, Ph.D. (1) · Vrisiis Kofina, DDS, MS (1)
PMID 16332231, PMID 22612364, PMID 25360528, PMID 26933467, PMID 28544150, PMID 31361269