20 completed, 5 recruiting, 5 unknown, 2 not yet recruiting. 11 Not applicable, 8 Phase 2, 5 Phase 4, 3 Phase 3, 1 Phase 1.
Follow Addison Disease: new trials by email Literature Review of Addison Disease trials Research Report on Addison Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Telehealth Music Therapy for Adults With Endocrine Disorder and Depression Telehealth Resource Oriented Music Therapy - Type 1 Diabetes, Hashimoto Disease | Not applicable | Recruiting | Appalachian State University | 10 | 2026-07-16 | 2026-07-30 |
| Risks of Ramadan Fasting in Patients With Primary Adrenal Insufficiency Treated With Prednisolone. Ramadan fasting - Primary Adrenal Insufficiency, Ramadan Fasting | Not applicable | Not yet recruiting | Hopital La Rabta | 35 | 2026-01-22 | 2026-01-26 |
| SPL Insufficiency Syndrome (SPLIS)/NPHS14: a SPLIS Observational Study and Patient Registry (International) no intervention - Sphingolipidoses, Enzyme Deficiency | Recruiting | University of California, San Francisco | 120 | 2025-04-22 | 2025-10-24 | |
| Natural History of Sphingosine Phosphate Lyase Insufficiency Syndrome (SPLIS) no intervention - Sphingosine Phosphate Lyase Insufficiency Syndrome (SPLIS) | Recruiting | University of California, San Francisco | 28 | 2025-04-22 | 2026-08-04 | |
| Growing up With the Young Endocrine Support System (YESS!) YESS! game, Snake '97, Transition-toolkit - Congenital Adrenal Hyperplasia, Hypogonadotropic Hypogonadism | Not applicable | Not yet recruiting | dr. Laura C. G. de Graaff-Herder | 160 | 2024-12-01 | 2023-09-07 |
| Risks of Intermittent Fasting in Patients With Primary Adrenal Insufficiency intermittent fasting - Primary Adrenal Insufficiency, Intermittent Fasting | Not applicable | Completed | Hopital La Rabta | 30 | 2024-03-04 | 2025-02-14 |
| Does Relative Hypoglycaemia &/or Sleep Disturbance Contribute to the Lethargy Observed in Addison's Disease Blood test - Addison Disease | Unknown | The Leeds Teaching Hospitals NHS Trust | 30 | 2022-04-07 | 2023-07-17 | |
| The Effects of Two Brands of Hydrocortisone Injected Intramuscularly Into Deltoid and Thigh Muscles Solu-Cortef 100 MG Injection, Hydrocortisone 100mg/ml - Addison's Disease | Phase 4 | Unknown | The London Clinic | 8 | 2022-03-14 | 2022-04-27 |
| Chronocort Versus Plenadren Replacement Therapy in Adults With Adrenal Insufficiency Chronocort, Plenadren - Primary Adrenal Insufficiency | Phase 2 | Completed | Neurocrine UK Limited | 58 | 2021-11-23 | 2026-09-14 |
| Additional Autoimmune Diseases With Type 1 Diabetes in Pediatrics at Diabetes Diagnosis and During Follow-up No intervention. - Type 1 Diabetes, Autoimmune Diseases | Unknown | Central Hospital, Nancy, France | 250 | 2021-03-15 | 2021-03-30 | |
| A Study of Markers of Glucocorticoid Effects in Patients With Addisons Disease (DOSCORT) Betamethasone - Addison Disease | Phase 4 | Completed | Göteborg University | 30 | 2021-03-02 | 2025-04-24 |
| Screening and Stimulation Testing for Residual Secretion of Adrenal Steroid Hormones in Autoimmune Addison's Disease Cosyntropin stimulation test, Baseline blood tests, 30-hour ambulatory sampling of intestinal fluid - Primary Adrenal Insufficiency | Not applicable | Active not recruiting | University of Bergen | 200 | 2018-09-26 | 2026-05-08 |
| Clinical Study on Circadian Genes Dysregulation in Patients With Glucocorticoid Disorders circadian gene expression evaluation - Cushing Syndrome, Adrenal Insufficiency | Not applicable | Recruiting | University of Roma La Sapienza | 44 | 2018-07-04 | 2026-10-20 |
| Vaginal Prednisone Administration for Prevention of Adrenal Crisis 100mg prednisone suppository - Adrenal Insufficiency | Phase 2 | Completed | Wuerzburg University Hospital | 12 | 2017-01-01 | 2017-06-20 |
| Biomarker(s) for Glucocorticoids Hydrocortisone, Placebo - Addison Disease | Not applicable | Completed | Vastra Gotaland Region | 11 | 2014-05-01 | 2021-04-12 |
| Ultradian Subcutaneous Hydrocortisone Infusion in Addison Disease and Congenital Adrenal Hyperplasia Solu-Cortef, Cortef - Addison Disease, Adrenal Hyperplasia Congenital | Phase 1 / Phase 2 | Completed | Haukeland University Hospital | 8 | 2014-03-27 | 2024-06-07 |
| Dual RElease Hydrocortisone Versus conventionAl Glucocorticoid replaceMent Therapy in Hypocortisolism (DREAM) Plenadren, Conventional glucocorticoid therapy - Primary Adrenal Insufficiency, Secondary Adrenal Insufficiency | Phase 4 | Completed | University of Roma La Sapienza | 89 | 2014-03-01 | 2019-04-25 |
| Cardiovascular Status in Adrenal Insufficiency Cardiovascular evaluation - Adrenal Insufficiency | Completed | Wuerzburg University Hospital | 68 | 2013-08-01 | 2018-02-08 | |
| Effect of Cortisol on Physical Exertion in Patients With Primary Adrenal Failure Hydrocortisone - Addison Disease | Phase 2 | Unknown | Haukeland University Hospital | 20 | 2013-06-01 | 2013-12-02 |
| Continuous Subcutaneous Hydrocortisone Infusion In Addison's Disease and Type 1 Diabetes Cortef, Solu-cortef - Addison Disease, Type 1 Diabetes | Phase 2 | Terminated | Haukeland University Hospital | 4 | 2013-04-24 | 2024-03-01 |
Showing 20 of 36. Sign in to see all of them.
Adrenal Insufficiency (9) · Diabetes Mellitus, Type 1 (5) · Adrenal Hyperplasia, Congenital (3) · Graves Disease (3) · Hashimoto Disease (3) · Celiac Disease (2) · Dehydration (2) · Endocrine System Diseases (2) · Hypoglycemia (2) · Liver Cirrhosis, Biliary (2) · Myasthenia Gravis (2) · Nephrotic Syndrome (2) · Obesity (2) · Rare Diseases (2)
Adrenal Gland Diseases (36) · Immune System Diseases (35) · Autoimmune Diseases (34) · Endocrine System Diseases (34) · Adrenal Insufficiency (27) · Nutritional and Metabolic Diseases (15) · Metabolic Diseases (13) · Pathological Conditions, Signs and Symptoms (8) · Glucose Metabolism Disorders (7) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (6) · Female Urogenital Diseases (6) · Female Urogenital Diseases and Pregnancy Complications (6) · Genetic Diseases, Inborn (6) · Male Urogenital Diseases (6) · Metabolism, Inborn Errors (6)
Hydrocortisone (11) · hydrocortisone hemisuccinate (4) · Hematologic Tests (2) · Betamethasone (1) · Cortisone (1) · Cosyntropin (1) · Dehydroepiandrosterone (1) · Ergometry (1) · Etomidate (1) · Glycyrrhiza glabra extract (1) · Injections (1) · Prednisone (1) · Propofol (1) · Sodium Chloride (1) · Solvents (1)
Haukeland University Hospital (5) · Hopital La Rabta (2) · University of California, San Francisco (2) · University of Roma La Sapienza (2) · University of Wuerzburg (2) · Wuerzburg University Hospital (2) · Appalachian State University (1) · Assistance Publique Hopitaux De Marseille (1) · Bruno Allolio (1) · Central Hospital, Nancy, France (1) · Göteborg University (1) · Insel Gruppe AG, University Hospital Bern (1) · Mayo Clinic (1) · National Center for Research Resources (NCRR) (1) · Neurocrine UK Limited (1)
Germany (6) · Norway (6) · United States (6) · United Kingdom (5) · Sweden (4) · France (2) · Italy (2) · Netherlands (2) · Switzerland (2) · Tunisia (2) · Australia (1) · Belgium (1) · Spain (1)
Bruno Allolio, MD (2) · Julie D Saba, MD, PhD (2) · Stefanie Hahner, MD (2) · Andrea M Isidori, MD, PhD (1) · Anna G Nilsson, MD, PhD (1) · Ernst A Lien, Prof. MD. (1) · Eystein Husebye, Professor (1) · Eystein S Husebye, M.D, Prof (1) · Eystein S Husebye, Prof, MD (1) · Felix G Riepe, MD (1) · Gudmundur Johannsson, Prof., MD (1) · Gudmundur Johannsson, Professor (1) · Katerina Simunkova, MD, PhD (1)
PMID 17684047, PMID 19383806, PMID 22112807, PMID 23672956, PMID 24170102, PMID 24944332, PMID 26914224, PMID 29129244, PMID 29229498, PMID 29618670, PMID 29846607, PMID 31853550, PMID 32392298, PMID 32419166, PMID 33236103, PMID 33821793, PMID 34213700, PMID 36042975, PMID 37172949, PMID 38053731, PMID 41108503, PMID 41552007, PMID 42824572
2009 (3), 2016 (1), R01HD113778 (1)