25 terminated. 25 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 25 | Terminated 25 |
Follow Ischemia: new trials by email Literature Review of Ischemia trials Research Report on Ischemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Very Early and Rapid Lowering Cholesterol With Evolocumab on Left Ventricular Remodeling in Patients With Anterior STEMI Undergoing Primary PCI Rosuvastatin 20 mg, Evolocumab 140 mg/1 ml Subcutaneous Solution [REPATHA] - ST Elevation Myocardial Infarction (STEMI) | Phase 4 | Terminated | Henan Institute of Cardiovascular Epidemiology | 119 | 2023-04-03 | 2026-05-22 |
| Study on Early Intra-aortic Balloon Pump Placement in Acute Decompensated Heart Failure Complicated by Cardiogenic Shock Early intra-aortic balloon pump (IABP) implantation, Standard of care as vasoactive agent - Cardiogenic Shock | Phase 4 | Terminated | Niguarda Hospital | 100 | 2020-05-04 | 2024-10-23 |
| Personalization of Long-Term Antiplatelet Therapy - RAPID EXTEND Active Comparator: Dual Antiplatelet Therapy (DAPT) - Aspirin 81 mg + Ticagrelor 60mg twice daily, Ticagrelor Monotherapy: Ticagrelor 60 mg twice daily, Personalized Therapy Arm: Aspirin 81 mg or Ticagrelor 60mg twice daily or Clopidogrel 75 mg once daily - Coronary Artery Disease, Myocardial Infarction | Phase 4 | Terminated | Ottawa Heart Institute Research Corporation | 39 | 2019-08-22 | 2026-05-06 |
| Randomized Evaluation of Beta Blocker and ACEI/ARB Treatment in MINOCA Patients - MINOCA-BAT Beta blocker, ACEI, ARB - Myocardial Infarction With Non-obstructive Coronary Arteries | Phase 4 | Terminated | Uppsala University | 198 | 2018-12-16 | 2023-11-27 |
| Cangrelor in ST-Elevation Myocardial Infarction to Decrease Infarct Size Cangrelor - STEMI - ST Elevation Myocardial Infarction | Phase 4 | Terminated | Khaled Ziada, MD | 23 | 2017-01-01 | 2020-06-30 |
| Sevoflurane and Percutaneous Coronary Intervention by Stent sevoflurane - Myocardial Infarction | Phase 4 | Terminated | Instituto Dante Pazzanese de Cardiologia | 701 | 2016-02-01 | 2020-04-28 |
| Acute Myocardial Necrosis and Depression: Antiplatelet Effect of Reuptake Inhibition of Serotonin Sertraline, No treatment, Placebo - Depression, Coronary Artery Disease | Phase 4 | Terminated | Assistance Publique - Hôpitaux de Paris | 2 | 2015-07-01 | 2016-05-03 |
| Thrombectomy Under Reopro Versus Alteplase to Treat Stoke abciximab IV and thrombectomy, alteplase 0.9mg/kg (10% by IV bolus following by 90% by 1 hour IV drip) - Infarction, Middle Cerebral Artery | Phase 4 | Terminated | SOS Attaque Cérébrale | 40 | 2013-09-01 | 2014-04-25 |
| Balloon Aortic Valvuloplasty Performed Without Heparin to Decrease Vascular and Bleeding Complications of the Procedure Heparin, NaCl - Aortic Stenosis, Non-rheumatic | Phase 4 | Terminated | University Hospital, Montpellier | 94 | 2013-01-24 | 2026-06-12 |
| Early Ablation Therapy for the Treatment of Ischemic Ventricular Tachycardia in Patients With Implantable Cardioverter Defibrillators Drug Treatment, Catheter Ablation - Ventricular Tachycardia, Ischemic | Phase 4 | Terminated | Biosense Webster, Inc. | 15 | 2012-06-01 | 2017-06-08 |
| Intracoronary Bolus Only Compared With Intravenous Bolus and 12-hours Infusion of Abciximab in Non-ST Elevation Myocardial Infarction. glycoprotein IIb/IIIa inhibitor (abciximab) - Myocardial Infarction, Angioplasty | Phase 4 | Terminated | Seoul National University Hospital | 150 | 2009-08-01 | 2026-04-27 |
| Ischemia Driven Enoxaparin Therapy in ACS Presenting as Low Risk (IDEAL) enoxaparin - Unstable Angina | Phase 4 | Terminated | Canadian Heart Research Centre | 11 | 2007-08-01 | 2016-01-27 |
| Dalteparin Versus Unfractionated Heparin In Patients With Acute Coronary Syndrome Dalteparin ( Fragmin), Unfractionated heparin - Angina, Unstable, Myocardial Infarction | Phase 4 | Terminated | Pfizer | 173 | 2007-06-01 | 2011-10-17 |
| Role of Plavix in Hemorrhagic and Ischemic Complications of Catheterization. clopidogrel 600 mg, arterial access sheath - Coronary Artery Disease, Myocardial Ischemia | Phase 4 | Terminated | Beth Israel Deaconess Medical Center | 18 | 2007-01-01 | 2017-04-14 |
| Zotarolimus-Versus Sirolimus-Versus PacliTaxel-Eluting Stent for Acute Myocardial Infarction Patients Endeavor, Medtronic, Cypher, Cordis, Taxus Liberte, Boston Scientific - Myocardial Infarction | Phase 4 | Terminated | Seung-Jung Park | 328 | 2006-10-01 | 2022-12-07 |
| Plaque Removal Versus Open Bypass Surgery For Critical Limb Ischemia Bypass, Silverhawk Plaque Excision - Peripheral Vascular Diseases | Phase 4 | Terminated | FoxHollow Technologies | 2006-10-01 | 2008-08-20 | |
| Randomized Study of Pregabalin for Pain Reduction in Patients With Rest Pain and Lower Limb Ischemia pregabalin, placebo - Critical Limb Ischemia, Arterial Occlusive Disease | Phase 4 | Terminated | Karolinska Institutet | 18 | 2006-06-01 | 2018-06-15 |
| Randomized Study of Aspirin Resistant Patients Undergoing Angioplasty eptifibatide - Angioplasty | Phase 4 | Terminated | Brigham and Women's Hospital | 1200 | 2006-03-01 | 2007-07-20 |
| Impact of Tight Glycaemic Control in Acute Myocardial Infarction Insulin (tight blood glucose control) - Myocardial Infarct, Hyperglycemia | Phase 4 | Terminated | Melbourne Health | 40 | 2005-10-01 | 2011-07-21 |
| Comparison of Standard Treatment Versus Standard Treatment Plus Extracorporeal Life Support (ECLS) in Myocardial Infarction Complicated With Cardiogenic Shock Extra-Corporeal Life Support -Impella 2.5 - Myocardial Infarction, Shock, Cardiogenic | Phase 4 | Terminated | University Hospital, Caen | 19 | 2005-06-01 | 2010-08-02 |
Showing 20 of 25. Sign in to see all of them.
Myocardial Infarction (15) · Coronary Artery Disease (4) · Angina, Unstable (2) · Chronic Limb-Threatening Ischemia (2) · Hemorrhage (2) · Myocardial Ischemia (2) · ST Elevation Myocardial Infarction (2) · Shock, Cardiogenic (2) · Stroke (2) · Acute Coronary Syndrome (1) · Agnosia (1) · Aortic Valve Stenosis (1) · Aphasia (1) · Arterial Occlusive Diseases (1)
Cardiovascular Diseases (25) · Pathologic Processes (25) · Pathological Conditions, Signs and Symptoms (25) · Vascular Diseases (23) · Heart Diseases (21) · Infarction (19) · Necrosis (19) · Myocardial Ischemia (17) · Arteriosclerosis (6) · Arterial Occlusive Diseases (5) · Coronary Disease (4) · Neurologic Manifestations (4) · Signs and Symptoms (4) · Myocardial Infarction (3)
Abciximab (2) · Clopidogrel (2) · Heparin (2) · 2'-deoxythymidylyl-(3'-5')-2'-deoxyadenosine (1) · Adrenergic beta-Antagonists (1) · Angiotensin Receptor Antagonists (1) · Angiotensin-Converting Enzyme Inhibitors (1) · Aspirin (1) · Catheter Ablation (1) · Dalteparin (1) · Drug Implants (1) · Enoxaparin (1) · Eptifibatide (1) · Infusions, Intravenous (1) · Insulin (1)
Assistance Publique - Hôpitaux de Paris (1) · Azienda Sanitaria Ospedaliera (1) · Beth Israel Deaconess Medical Center (1) · Biosense Webster, Inc. (1) · Boehringer Ingelheim (1) · Brigham and Women's Hospital (1) · Canadian Heart Research Centre (1) · FoxHollow Technologies (1) · Henan Institute of Cardiovascular Epidemiology (1) · Instituto Dante Pazzanese de Cardiologia (1) · Karolinska Institutet (1) · Khaled Ziada, MD (1) · Melbourne Health (1) · National Cerebral and Cardiovascular Center, Japan (1) · Niguarda Hospital (1)
France (6) · United States (6) · Italy (4) · Canada (3) · Norway (3) · Sweden (3) · Australia (2) · Austria (2) · Belgium (2) · Brazil (2) · Germany (2) · Greece (2) · Hungary (2) · Poland (2) · South Korea (2)
Anatoly Langer, MD, MSc (1) · Andrea Natale, MD (1) · Andrew T Yan, MD (1) · Bertil Lindahl, Prof (1) · Daniel I Simon, MD (1) · David Callans, MD (1) · David Fitchett, MD (1) · David Wilber, MD (1) · Derek YF So, MD FRCPC (1) · Doron Zahger, MD (1) · Eric Wahlberg, MD. PhD (1) · Florence Leclercq, PU PH (1) · Francis Marchlinski, MD (1) · Hyun-Jae Kang, Prof (1)
PMID 16488800, PMID 18662628, PMID 20562693, PMID 21545942, PMID 22744792, PMID 26296299, PMID 33203618, PMID 33258102, PMID 35402691, PMID 40162941, PMID 42246870