14 completed, 3 unknown, 2 recruiting, 1 not yet recruiting. 23 Phase 2, 6 Phase 3, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 23 | Completed 14, Unknown 3, Recruiting 2, Not yet recruiting 1, Suspended 1, Terminated 1, Withdrawn 1 |
| Phase 3 | 6 | Completed 5, Recruiting 1 |
| Phase 1 | 2 | Completed 1, Unknown 1 |
Follow Intraoperative Complications: new trials by email Literature Review of Intraoperative Complications trials Research Report on Intraoperative Complications
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Vitamin C Administration on Intraoperative Bleeding in Patients Undergoing Sinusoscopy Ascorbic acid, Placebo - Chronic Rhinosinusitis, Intraoperative Bleeding | Phase 2 | Not yet recruiting | Assiut University | 78 | 2026-11-01 | 2026-10-08 |
| Prophylactic Intravenous Calcium Gluconate to Decrease Blood Loss at Time of Cesarean Delivery in Pregnant Patients at High Risk for Uterine Atony Calcium Gluconate, Saline - Blood Loss, Surgical, Blood Loss, Postoperative | Phase 2 | Recruiting | University of Michigan | 140 | 2025-10-20 | 2026-07-24 |
| The Effect of Adding Either Propofol or Ketamine to Magnesium and Lidocaine Infusions in Nasal Surgeries. Intravenous Infusion of propofol, lidocaine, Magnesium sulfate, Intravenous infusion of ketamine, lidocaine, Magnesium sulfate, Intravenous infusion of dexmedetomidine, lidocaine, Magnesium sulfate - Intraoperative Bleeding | Phase 2 / Phase 3 | Recruiting | Ain Shams University | 90 | 2024-06-15 | 2024-10-09 |
| Effectiveness of Different Fibrinogen Preparations in Restoring Clot Firmness FibCLOT, RiaSTAP - Hypofibrinogenemia, Surgical Blood Loss | Phase 2 | Completed | IRCCS Policlinico S. Donato | 40 | 2023-03-20 | 2024-02-28 |
| Extended Cold Stored Apheresis Platelets in Cardiac Surgery Patients Cold stored platelets in 100% plasma stored for 10-14 days, Room temperature stored platelets in 100% plasma stored for up to 7 days - Hemorrhage, Platelets; Defect | Phase 1 / Phase 2 | Unknown | Moritz Stolla, MD | 30 | 2022-02-21 | 2023-07-27 |
| Comparative Study Between Oxytocin Versus Tranexamic Acid and Ethamsylate Oxytocin ,Tranexamic acid and Ethamsylate - Blood Loss, Surgical, Blood Loss, Postoperative | Phase 1 / Phase 2 | Completed | Egymedicalpedia | 230 | 2020-04-01 | 2022-03-17 |
| Oral Tranexamic Acid vs. Oral Aminocaproic Acid to Reduce Blood Loss After Total Hip Replacement Aminocaproic Acid 1000Mg Tab, Tranexamic acid tablets - Blood Loss, Surgical | Phase 2 | Completed | Carlos A Acosta-Olivo | 90 | 2020-02-06 | 2021-04-28 |
| Use of Tranexamic Acid in Liposculpture Tranexamic acid - Blood Loss, Surgical | Phase 2 / Phase 3 | Completed | Total Definer Research Group | 141 | 2019-01-17 | 2020-06-12 |
| TIVA vs Inhalational Mode of Anaesthesia Injection dexmedetomidine, Injection, Propofol, 10 Mg, sevoflurane - Anesthesia Awareness | Phase 2 | Completed | Rajiv Gandhi Cancer Institute & Research Center, India | 100 | 2019-01-10 | 2020-02-19 |
| A Study of Human Multi-Sensory Integration Propofol, Ketamine Injectable Product - Anesthesia Awareness | Phase 2 | Suspended | University of Pennsylvania | 40 | 2018-07-30 | 2023-02-08 |
| Liberal Versus Restrictive Fluid Protocols in Adults Ringer lactate - Intraoperative Complications | Phase 2 | Completed | Assiut University | 80 | 2018-01-28 | 2019-07-09 |
| PIPAC for Peritoneal Metastases of Colorectal Cancer repetitive ePIPAC-OX - Colorectal Neoplasms, Peritoneal Neoplasms | Phase 2 | Completed | Koen Rovers | 20 | 2017-10-01 | 2019-10-15 |
| Effect of Topical and Systemic Tranexemic Acid on Bleeding During Ear Exploration Surgery Tranexamic Acid, Adrenalin - Intraoperative Bleeding | Phase 2 | Unknown | Assiut University | 90 | 2017-04-01 | 2017-04-13 |
| Lidocaine in ERAS for FESS Lidocaine, Normal saline - Intraoperative Bleeding | Phase 2 | Completed | Assiut University | 43 | 2017-02-09 | 2022-04-28 |
| Effects of Terlipressin on Blood Loss and Transfusion Requirements During Major Liver Resection. Terlipressin, normal saline - Hepatectomy, Surgical Blood Loss, Terlipressin | Phase 2 | Completed | Assiut University | 84 | 2015-09-01 | 2017-12-27 |
| Tranexamic Acid in Reverse Total Shoulder Arthroplasty Tranexamic Acid, Placebo - Shoulder Joint Disease, Complications; Arthroplasty | Phase 2 / Phase 3 | Completed | Corewell Health East | 116 | 2013-09-01 | 2017-06-19 |
| Single Dose of Tranexamic Acid and Blood Loss, in Elderly Patients With Hip Fracture Tranexamic Acid 15mg/kg , iv, Single Dose, Normal Saline, 100mg, iv, Singe dose - Blood Loss, Surgical, Hip Fractures | Phase 2 | Unknown | National and Kapodistrian University of Athens | 200 | 2013-01-01 | 2017-08-16 |
| Weighted Versus Uniform Dose of Tranexamic Acid in Patients Undergoing Primary, Knee Arthroplasty Tranexamic Acid standard dose, Females Tranexamic Acid weighted dose, Females receiving a uniform dose of TA - Osteoarthritis, Intraoperative Bleeding | Phase 2 / Phase 3 | Completed | Rush University Medical Center | 65 | 2012-05-01 | 2017-12-13 |
| Use of a Novel Fibrin Sealant in Total Knee Arthroplasty Evicel Fibrin Spray - Osteoarthritis, Intraoperative Bleeding | Phase 2 / Phase 3 | Completed | Rush University Medical Center | 73 | 2012-05-01 | 2016-02-09 |
| Transumbilical Versus Transvaginal Specimen Retrieval at Minilaparoscopy TRANSVAGINAL SPECIMEN EXTRACTION, TRANSUMBILICAL SPECIMEN EXTRACTION - Postoperative Pain, Patients Satisfaction | Phase 2 / Phase 3 | Completed | Università degli Studi dell'Insubria | 56 | 2011-07-01 | 2012-02-24 |
Showing 20 of 23. Sign in to see all of them.
Blood Loss, Surgical (18) · Hemorrhage (10) · Postoperative Complications (4) · Postoperative Hemorrhage (4) · Intraoperative Awareness (2) · Osteoarthritis (2) · Afibrinogenemia (1) · Aortic Valve Stenosis (1) · Appendiceal Neoplasms (1) · Arthritis (1) · Blood Platelet Disorders (1) · Cecal Neoplasms (1) · Colorectal Neoplasms (1) · Drug-Related Side Effects and Adverse Reactions (1)
Pathological Conditions, Signs and Symptoms (23) · Pathologic Processes (22) · Hemorrhage (8) · Postoperative Complications (3) · Arthritis (2) · Cardiovascular Diseases (2) · Hematologic Diseases (2) · Hemic and Lymphatic Diseases (2) · Joint Diseases (2) · Musculoskeletal Diseases (2) · Neoplasms by Site (2) · Rheumatic Diseases (2) · Signs and Symptoms (2) · Urogenital Diseases (2)
Tranexamic Acid (6) · Saline Solution (5) · Lidocaine (2) · Propofol (2) · Ringer's Lactate (2) · Aminocaproic Acid (1) · Antifibrinolytic Agents (1) · Ascorbic Acid (1) · Calcium Gluconate (1) · Dexmedetomidine (1) · Epinephrine (1) · Ethamsylate (1) · Fibrinogen (1) · Injections (1) · Ketamine (1)
Assiut University (5) · Rush University Medical Center (2) · Ain Shams University (1) · Carlos A Acosta-Olivo (1) · Corewell Health East (1) · Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (1) · Egymedicalpedia (1) · Heinrich-Heine University, Duesseldorf (1) · IRCCS Policlinico S. Donato (1) · Koen Rovers (1) · Moritz Stolla, MD (1) · National and Kapodistrian University of Athens (1) · Rajiv Gandhi Cancer Institute & Research Center, India (1) · Sangart (1) · Total Definer Research Group (1)
United States (8) · Egypt (6) · Italy (2) · Mexico (2) · Colombia (1) · Germany (1) · Greece (1) · India (1) · Netherlands (1)
Andrew L Sternlicht, MD (1) · AnneMarie Opipari, MD (1) · Brett R Levine, MD (1) · Carlos Acosta-Olivo, PhD (1) · Djamila Boerma, MD, PhD (1) · Ignace de Hingh, MD, PhD (1) · John Ulatowski, M.D., Ph.D. (1) · Kevin Baker, PhD (1) · Marco Ranucci, MD (1) · Mark Belkin, BS (1) · Max Kelz, MD, PhD (1) · Michael J Wiater, M.D. (1) · Moritz Stolla, MD (1)
PMID 10565650, PMID 11679600, PMID 28244907, PMID 29107495, PMID 29723672, PMID 30079635, PMID 31352425, PMID 31491796, PMID 32572849, PMID 33544279, PMID 34757489, PMID 37993560, PMID 39383100, PMID 40204440
2017 (1)