33 terminated. 33 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 33 | Terminated 33 |
Follow Insulin Resistance: new trials by email Literature Review of Insulin Resistance trials Research Report on Insulin Resistance
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Regulation of Insulin Secretion by the GLP-1 Receptor Exendin (9-39), Dexamethasone, Hyperglycemic Clamp - Insulin Secretion | Phase 4 | Terminated | VA Office of Research and Development | 6 | 2018-07-01 | 2024-12-12 |
| Use of NPH Versus Basal Bolus Insulin for Steroid Induced Hyperglycemia NPH Insulin, glargine, Insulin Aspart - Hyperglycemia Steroid-induced, Insulin Resistance, Diabetes | Phase 4 | Terminated | Northwestern University | 3 | 2018-03-27 | 2020-09-11 |
| Randomised Open Label Study of Insulin Degludec Versus Insulin Glargine U100 in Ramadan Insulin Degludec U100, Insulin Glargine - Type2 Diabetes | Phase 4 | Terminated | Weill Cornell Medical College in Qatar | 273 | 2018-01-07 | 2020-06-09 |
| Metformin, Vitamin D, and Depression in Polycystic Ovary Syndrome (PCOS) Trial Metformin, Vitamin D - PCOS, Depression | Phase 4 | Terminated | University of California, San Francisco | 5 | 2017-12-12 | 2021-02-09 |
| A Clinical Trial of YMC017 in Hypertensive and Hypercholesterolemic Patients With Metabolic Syndrome Telmisartan 40mg + Rosuvastatin 20mg, Telmisartan 80mg + Rosuvastatin 20mg, Telmisartan 40mg, 80 mg - Metabolic Syndrome | Phase 4 | Terminated | Yuhan Corporation | 55 | 2016-10-01 | 2019-04-12 |
| Liraglutide for HIV-associated Neurocognitive Disorder Liraglutide - HIV Infection, Diabetes Mellitus Type 2 | Phase 4 | Terminated | Temple University | 4 | 2016-09-01 | 2022-07-29 |
| Insulin Resistance and Mild Cognitive Impairment (IRMCI) Study Metformin, Intensive Lifestyle Intervention, Standard LIfestyle Recommendation - Mild Cognitive Impairment, Insulin Resistance | Phase 4 | Terminated | SingHealth Polyclinics | 105 | 2015-03-11 | 2023-01-11 |
| Comparison of Insulin Therapy in Treating Post-Transplant Diabetes Insulin, Isophane, insulin glargine - Diabetes Mellitus | Phase 4 | Terminated | Inova Health Care Services | 2 | 2013-11-27 | 2022-07-26 |
| Aldosterone Antagonism and Microvascular Function Eplerenone, Placebo - Abdominal Obesity Metabolic Syndrome, Insulin Resistance | Phase 4 | Terminated | Maastricht University Medical Center | 25 | 2013-10-01 | 2018-11-05 |
| The Effects of Metformin on Functional Capacity in Individuals With Peripheral Artery Disease-Related Intermittent Claudication Metformin, Placebo - Peripheral Arterial Disease, Intermittent Claudication | Phase 4 | Terminated | Baker Heart and Diabetes Institute | 2 | 2013-07-01 | 2016-02-09 |
| Effect of 13-Week Treatment With Vildagliptin as Add-On Therapy to Improve Glucose Variability in Type II Diabetes Vildagliptin, Insulin, Placebo - Type 2 Diabetes Mellitus | Phase 4 | Terminated | Novartis Pharmaceuticals | 191 | 2013-05-01 | 2019-06-05 |
| Comparison of Neutral Protamine Hagedorn (NPH) and Lantus Based Insulin Regimen in the Management of Hypoglycemia in the Hospitalized Patients in Noncritical Care Setting NPH and regular insulin, glargine and humalog - Type 2 Diabetes Mellitus | Phase 4 | Terminated | Riverside University Health System Medical Center | 52 | 2013-04-01 | 2017-09-28 |
| Pioglitazone for the Treatment of Bipolar Depression Pioglitazone, Placebo - Bipolar Disorder, Insulin Resistance | Phase 4 | Terminated | University Hospitals Cleveland Medical Center | 37 | 2012-09-01 | 2017-01-27 |
| Insulin Therapy for Post-transplant Glucocorticoid Induced Hyperglycemia Neutral protamine hagedorn (NPH) insulin, Regular human insulin or Insulin Aspart, Insulin glargine - Post-Transplant Glucocorticoid Induced Diabetes | Phase 4 | Terminated | Vancouver General Hospital | 5 | 2012-08-01 | 2015-12-09 |
| Acute and Long-Term Outcome Investigations of Fenofibrate on Severely Burned Patients Fenofibrate, Sugar Pill - Second or Third Degree Burns | Phase 4 | Terminated | The University of Texas Medical Branch, Galveston | 3 | 2012-05-01 | 2019-11-29 |
| Metformin for Ectopic Fat Deposition and Metabolic Markers in Polycystic Ovary Syndrome (PCOS) Metformin, Placebo - Polycystic Ovary Syndrome, Non-Alcoholic Fatty Liver Disease | Phase 4 | Terminated | Columbia University | 3 | 2011-09-08 | 2025-07-02 |
| Effect of Niacin/Laropiprant on Postprandial Lipoprotein Metabolism in Patients With Dyslipoproteinemia Niacin/ Laropiprant - Hyperlipoproteinemia, Metabolic Syndrome | Phase 4 | Terminated | Ludwig-Maximilians - University of Munich | 12 | 2011-06-01 | 2014-04-10 |
| Rifaximin in Fatty Liver Disease Rifaximin - Nonalcoholic Fatty Liver Disease, NAFLD | Phase 4 | Terminated | Imperial College London | 15 | 2011-05-01 | 2020-10-28 |
| Carbohydrate Consumption as a Factor in Aspart Dosing aspart, aspart- Insulin - Diabetes | Phase 4 | Terminated | Rush University Medical Center | 14 | 2011-04-01 | 2023-05-01 |
| One-Year Trial Of Oral Ziprasidone In Patients With Metabolic Syndrome Ziprasidone HCL (oral) - Schizophrenia and Disorders With Psychotic Features | Phase 4 | Terminated | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 172 | 2008-12-01 | 2021-03-03 |
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Metabolic Syndrome (13) · Diabetes Mellitus (6) · Diabetes Mellitus, Type 2 (6) · Cardiovascular Diseases (3) · Glucose Intolerance (3) · Obesity (3) · Polycystic Ovary Syndrome (3) · Hypertension (2) · Inflammation (2) · Non-alcoholic Fatty Liver Disease (2) · Schizophrenia (2) · Abdominal obesity metabolic syndrome (1) · Acne Vulgaris (1) · Amenorrhea (1)
Glucose Metabolism Disorders (33) · Hyperinsulinism (33) · Metabolic Diseases (33) · Nutritional and Metabolic Diseases (33) · Endocrine System Diseases (14) · Pathological Conditions, Signs and Symptoms (11) · Signs and Symptoms (7) · Diabetes Mellitus (5) · Mental Disorders (5) · Nutrition Disorders (5) · Pathologic Processes (5) · Body Weight (4) · Digestive System Diseases (4) · Genital Diseases (4)
Insulin Glargine (6) · Metformin (6) · Insulin (3) · Insulin Aspart (3) · Isophane Insulin, Human (3) · Eplerenone (2) · Insulin, Isophane (2) · Pioglitazone (2) · Ramipril (2) · Ribavirin (2) · Rosiglitazone (2) · Sugars (2) · Acarbose (1) · Amlodipine (1) · Aripiprazole (1)
Assistance Publique - Hôpitaux de Paris (1) · Baker Heart and Diabetes Institute (1) · Beth Israel Medical Center (1) · Brigham and Women's Hospital (1) · Bristol-Myers Squibb (1) · Columbia University (1) · Imperial College London (1) · Inova Health Care Services (1) · Ludwig-Maximilians - University of Munich (1) · Maastricht University Medical Center (1) · Merck Sharp & Dohme LLC (1) · Northwestern University (1) · Novartis (1) · Novartis Pharmaceuticals (1) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (1)
United States (16) · Canada (3) · United Kingdom (3) · France (2) · Germany (2) · Australia (1) · Belgium (1) · Czechia (1) · Greece (1) · Hungary (1) · Mexico (1) · Netherlands (1) · Qatar (1) · Singapore (1) · South Africa (1)
Aruna Das Pradhan, MD, MPH (1) · Aviva B Sopher, MD, MS, MS (1) · Breay W Paty, MD, FRCPC (1) · Bronwyn A Kingwell, PhD (1) · Cecile Teinturier, MD (1) · Cherie Vaz, MD Dipl ABOM (1) · Chung-Kay Koh, MD (1) · Colin N Menezes, FCP(SA) (1) · David A Ehrmann, M.D. (1) · David D'Alessio, MD (1) · David Kemp, MD (1) · David N Herndon, MD (1) · Douglas Meyer, M.D. (1) · Esra Tasali, M.D. (1)
PMID 10332663, PMID 17259511, PMID 17683100, PMID 18172212, PMID 18647805, PMID 19755697, PMID 19885233, PMID 21123449, PMID 21387555, PMID 21733508, PMID 22341881, PMID 22784834, PMID 24568177, PMID 25003376, PMID 26474657, PMID 27995731, PMID 29275373, PMID 30699881
K23DK074439 (1), R01HL075079 (1)