16 terminated. 16 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 16 | Terminated 16 |
| Phase 2 | 2 | Terminated 2 |
Follow Insulin Resistance: new trials by email Literature Review of Insulin Resistance trials Research Report on Insulin Resistance
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Individualizing Automated Closed Loop Glucose Control Through Pharmacokinetic Profiling in an Insulin-Only Bionic Pancreas Humalog, Novolog, BC222 insulin lispro - Type 1 Diabetes Mellitus | Phase 2 / Phase 3 | Terminated | Massachusetts General Hospital | 20 | 2019-03-19 | 2022-12-09 |
| Metformin in Patients Initiating ADT as Prevention and Intervention of Metabolic Syndrome Metformin, Placebo Oral Tablet - Prostate Cancer, Metabolic Syndrome | Phase 3 | Terminated | Canadian Urologic Oncology Group | 166 | 2018-07-12 | 2026-07-29 |
| Evaluation of Preoperative Oral Rehydration Solution in Colectomy Oral rehydration solution - Insulin Resistance, Postoperative Complication | Phase 3 | Terminated | Seoul National University Hospital | 10 | 2014-02-01 | 2017-04-27 |
| Mechanisms of Improved Wound Healing and Protein Synthesis of Insulin and Metformin Metformin, Sugar pill - Insulin Resistance, Hypermetabolism | Phase 2 / Phase 3 | Terminated | The University of Texas Medical Branch, Galveston | 36 | 2012-11-01 | 2019-11-29 |
| Study of Liraglutide in Individuals With Type 2 Diabetes Using Insulin liraglutide, placebo injection - Type 2 Diabetes | Phase 3 | Terminated | University of Manitoba | 52 | 2012-08-01 | 2016-01-21 |
| Effect of Weight and Insulin Sensitivity on Reproductive Function in PCOS Metformin, Dietary Restriction, Exercise Training - Polycystic Ovary Syndrome | Phase 3 | Terminated | Pennington Biomedical Research Center | 32 | 2012-05-01 | 2022-03-15 |
| One-Year Trial of Oral Ziprasidone in Bipolar Patients With Metabolic Syndrome Ziprasidone HCL (oral) - Bipolar Disorder | Phase 3 | Terminated | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 13 | 2010-07-01 | 2021-03-03 |
| Vitamin D Supplementation in CAD and Postchallenge Hyperglycemia vitamin D - Coronary Artery Disease, Postprandial Hyperglycemia | Phase 3 | Terminated | Medical University of Graz | 22 | 2010-06-01 | 2015-04-17 |
| Pioglitazone vs. Placebo in Association With Pegylated Interferon and Ribavirin in HCV Patients With Insulin Resistance Pioglitazone, Placebo - Chronic Hepatitis C, Insulin Resistance | Phase 3 | Terminated | French National Agency for Research on AIDS and Viral Hepatitis | 40 | 2009-12-03 | 2017-01-24 |
| Trial Comparing the Effects of Aripiprazole With Those of Standard of Care on Non-HDL Cholesterol in Patients With Schizophrenia or Bipolar I Disorder Who Have Metabolic Syndrome Aripiprazole, Oanzapine, risperidone, or quetiapine - Schizophrenia, Schizoaffective Disorder | Phase 3 | Terminated | Otsuka Pharmaceutical Development & Commercialization, Inc. | 64 | 2009-04-01 | 2013-12-02 |
| Long-Term Effect of 10 mg Versus 20 mg Rimonabant in Overweight or Obese Patients rimonabant (SR141716) - Obesity, Weight Loss | Phase 3 | Terminated | Sanofi | 331 | 2008-04-01 | 2009-06-17 |
| Effect of Exercise and Phytoestrogen on Bone, Metabolic Syndrome Criteria and Complaints of the Early Menopause exercise, exercise + cimicifuga racemosa, wellness control, placebo - Bone Diseases, Metabolic Syndrome X | Phase 3 | Terminated | University of Erlangen-Nürnberg Medical School | 126 | 2008-04-01 | 2015-05-28 |
| Rosiglitazone and Insulin Resistance in Renally Impaired Patients rosiglitazone - Chronic Kidney Disease, Insulin Resistance | Phase 3 | Terminated | Leiden University Medical Center | 30 | 2007-04-01 | 2008-10-02 |
| Estimating and Reducing the Cardiovascular Risk of Patients With Schizophrenia Drugs From Lipid Measures and Ischemic Electrocardiographic Changes aripiprazole (Abilify), ziprasidone (Geodon) - Schizophrenia, Schizoaffective Disorder | Phase 3 | Terminated | Northwestern University | 48 | 2006-01-01 | 2025-10-02 |
| Ppar-Gamma EliminAtes Restenosis Longevity Study: PEARLS rosiglitazone - Metabolic Syndrome | Phase 3 | Terminated | Medstar Health Research Institute | 200 | 2006-01-01 | 2008-05-22 |
| Atherosclerosis Underlying Development Assessed by Intima-Media Thickness in Patients on Rimonabant Rimonabant, Placebo (for Rimonabant) - Carotid Artery Plaque, Arteriosclerosis | Phase 3 | Terminated | Sanofi | 661 | 2005-08-01 | 2016-05-20 |
Metabolic Syndrome (7) · Bipolar Disorder (2) · Hyperglycemia (2) · Motor Activity (2) · Obesity (2) · Psychotic Disorders (2) · Schizophrenia (2) · Arteriosclerosis (1) · Body Weight (1) · Bone Diseases (1) · Burns (1) · Carotid Artery Diseases (1) · Carotid Stenosis (1) · Coronary Artery Disease (1)
Glucose Metabolism Disorders (16) · Hyperinsulinism (16) · Metabolic Diseases (16) · Nutritional and Metabolic Diseases (16) · Pathological Conditions, Signs and Symptoms (6) · Endocrine System Diseases (4) · Urogenital Diseases (4) · Cardiovascular Diseases (3) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Genital Diseases (3) · Mental Disorders (3) · Nutrition Disorders (3) · Pathologic Processes (3)
Metformin (3) · Aripiprazole (2) · Exercise (2) · Rimonabant (2) · Rosiglitazone (2) · ziprasidone (2) · Caloric Restriction (1) · Diet Therapy (1) · Insulin (1) · Insulin Aspart (1) · Insulin Lispro (1) · Liraglutide (1) · Pioglitazone (1) · Quetiapine Fumarate (1) · Resistance Training (1)
Sanofi (2) · Canadian Urologic Oncology Group (1) · French National Agency for Research on AIDS and Viral Hepatitis (1) · Leiden University Medical Center (1) · Massachusetts General Hospital (1) · Medical University of Graz (1) · Medstar Health Research Institute (1) · Northwestern University (1) · Otsuka Pharmaceutical Development & Commercialization, Inc. (1) · Pennington Biomedical Research Center (1) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (1) · Seoul National University Hospital (1) · The University of Texas Medical Branch, Galveston (1) · University of Erlangen-Nürnberg Medical School (1) · University of Manitoba (1)
United States (6) · Canada (5) · Netherlands (3) · France (2) · Austria (1) · Croatia (1) · Finland (1) · Germany (1) · Hungary (1) · Romania (1) · South Korea (1) · Spain (1) · United Kingdom (1)
Bernie Eigl, MD (1) · David N Herndon, MD (1) · John JP Kastelein, MD (1) · Leanne M Redman, PhD (1) · Michael Bebenek, MS (1) · Nawaid Usmani, MD (1) · Ron Waksman, MD (1) · Steven J Russell, MD, PhD (1) · Sung-Bum Kang, Ph.D. (1) · Thomas R. Pieber, MD (1) · Tianlai Tang, M.D. (1) · Vincent C Woo, MD FRCPC (1)
PMID 21610270, PMID 28323951, PMID 30377436, PMID 32994091, PMID 40711960
2005 (1), 2008 (1), R00HD060762 (1)