7 completed, 4 unknown, 3 recruiting, 1 enrolling by invitation. 16 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 16 | Completed 7, Unknown 4, Recruiting 3, Enrolling by invitation 1, Terminated 1 |
Follow Hypothalamic Neoplasms: new trials by email Literature Review of Hypothalamic Neoplasms trials Research Report on Hypothalamic Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hydrocortisone in Hormone Replacement Therapy for Large Pituitary Neuroendocrine Tumors Hormone replacement therapy, Placebo - Pituitary Adenoma, Pituitary Neuroendocrine Tumor | Phase 4 | Recruiting | Beijing Tiantan Hospital | 882 | 2024-12-04 | 2025-01-14 |
| Cabergoline in the Management of Nonfunctioning Pituitary Adenoma Cabergoline 0.5 MG - Pituitary Adenoma, MRI | Phase 4 | Enrolling by invitation | National Taiwan University Hospital | 30 | 2024-05-20 | 2025-06-24 |
| Comparison of Postoperative Recovery of Sevoflurane and Propofol After Transsphenoidal Surgery sevoflurane, propofol - Pituitary Adenoma | Phase 4 | Completed | Peking Union Medical College Hospital | 252 | 2023-05-03 | 2025-06-08 |
| Infraorbital Nerve Block for Endoscopic Transsphenoidal Approach to Remove Pituitary Tumor dexmedetomidine 5 mcg mixed with 0.5% plain bupivacaine - Intraoperative Pain Control | Phase 4 | Unknown | Chiang Mai University | 63 | 2021-07-01 | 2021-03-05 |
| 68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors. Ga68-DOTATATE-PET/MRI - CNS Tumors, Meningioma | Phase 4 | Recruiting | Weill Medical College of Cornell University | 200 | 2019-09-04 | 2026-10-30 |
| The Effect of Local Anesthesia on Postopanalgesia in Patients Using Head Holder lidocaine was administered subcutaneously at 0.5% concentration., lidocaine was administered subcutaneously at 1% concentration. - Postoperative Pain, Acute | Phase 4 | Completed | Kocaeli University | 75 | 2018-01-10 | 2026-06-05 |
| Prophylactic Oral Antibiotics on Sinonasal Outcomes Following Endoscopic Transsphenoidal Surgery for Pituitary Lesions Placebo, Oral Antibiotics cefdinir or trimethoprim/sulfamethoxazole - Antibiotics, Pituitary Adenoma | Phase 4 | Recruiting | St. Joseph's Hospital and Medical Center, Phoenix | 116 | 2017-07-01 | 2018-08-15 |
| Comparative Low and High Dose of Dexmedethomidine in Pituitary Tumor Removal by Transphenoid Approach high dose dexmedethomidine, low dose dexmedethomidine - Pituitary Tumor | Phase 4 | Unknown | Mahidol University | 124 | 2016-05-01 | 2017-05-30 |
| Effect of Dexmedetomidine on Plasmatic Cortisol Response in Transsphenoidal Surgery Dexmedetomidine, Sodium Chloride 0.9% - Pituitary Neoplasms | Phase 4 | Unknown | Pontificia Universidad Catolica de Chile | 40 | 2015-09-01 | 2016-10-12 |
| Analgesia Regimens Following Trans-sphenoidal Surgery for Pituitary Tumors IV Caldolor, IV Placebo - Pituitary Tumor, Pain | Phase 4 | Completed | St. Joseph's Hospital and Medical Center, Phoenix | 62 | 2015-02-01 | 2021-10-21 |
| Effect of Perioperative Glucocorticoid Replacement on Prognosis of Surgical Patients With Sellar Lesions Hydrocortisone, Prednisone - Pituitary Neoplasms, Craniopharyngiomas | Phase 4 | Unknown | West China Hospital | 100 | 2013-08-01 | 2014-07-15 |
| Study to Allow Access to Pasireotide for Patients Benefiting From Pasireotide Treatment in Novartis-sponsored Studies Pasireotide, Cabergoline, Pasireotide LAR - Cushing's Disease, Acromegaly | Phase 4 | Completed | RECORDATI GROUP | 337 | 2013-06-10 | 2024-10-01 |
| A Pilot Study of Pre- and Post-operative Use of Somatuline Depot. lanreotide - Acromegaly | Phase 4 | Terminated | Saint John's Cancer Institute | 4 | 2013-05-01 | 2021-09-30 |
| Efficacy of Octreotide Acetate and Cabergoline in Patients With Acromegaly Octreotide acetate and cabergoline/Octrotide and Somavert - Acromegaly | Phase 4 | Completed | Novartis Pharmaceuticals | 20 | 2006-03-01 | 2017-03-06 |
| Surgical Debulking of Pituitary Adenomas Octreotide LAR, transsphenoidal surgery - Pituitary Adenoma | Phase 4 | Completed | NYU Langone Health | 41 | 2004-04-01 | 2016-08-29 |
| Dose Escalation of Octreotide-LAR as First-Line Therapy in Resistant Acromegaly Octreotide-LAR - Acromegaly | Phase 4 | Completed | Federico II University | 50 | 1995-01-01 | 2007-04-17 |
Pituitary Neoplasms (16) · Acromegaly (4) · Brain Neoplasms (1) · Central Nervous System Neoplasms (1) · Craniopharyngioma (1) · Dumping Syndrome (1) · Esthesioneuroblastoma, Olfactory (1) · Gigantism (1) · Hemangioblastoma (1) · Medulloblastoma (1) · Melanoma (1) · Meningioma (1) · Neoplasms (1) · Neuroendocrine Tumors (1) · Pain (1)
Brain Diseases (16) · Central Nervous System Diseases (16) · Endocrine Gland Neoplasms (16) · Endocrine System Diseases (16) · Hypothalamic Diseases (16) · Neoplasms by Site (16) · Nervous System Diseases (16) · Nervous System Neoplasms (16) · Supratentorial Neoplasms (16) · Brain Neoplasms (15) · Central Nervous System Neoplasms (15) · Neoplasms (15) · Pituitary Diseases (15) · Bone Diseases (4)
Cabergoline (3) · Dexmedetomidine (3) · Cefdinir (1) · Hormone Replacement Therapy (1) · Hydrocortisone (1) · Ibuprofen (1) · Octreotide (1) · Prednisone (1) · Propofol (1) · Saline Solution (1) · Sevoflurane (1) · Sodium Chloride (1) · Sulfamethoxazole (1) · Trimethoprim (1) · lanreotide (1)
St. Joseph's Hospital and Medical Center, Phoenix (2) · Beijing Tiantan Hospital (1) · Chiang Mai University (1) · Federico II University (1) · Kocaeli University (1) · Mahidol University (1) · NYU Langone Health (1) · National Taiwan University Hospital (1) · Novartis Pharmaceuticals (1) · Peking Union Medical College Hospital (1) · Pontificia Universidad Catolica de Chile (1) · RECORDATI GROUP (1) · Saint John's Cancer Institute (1) · Weill Medical College of Cornell University (1) · West China Hospital (1)
United States (6) · China (3) · Germany (2) · Italy (2) · Taiwan (2) · Thailand (2) · Turkey (Türkiye) (2) · Argentina (1) · Belgium (1) · Brazil (1) · Bulgaria (1) · Canada (1) · Chile (1) · France (1) · Greece (1)
Andrew Little, MD (1) · Andrew S Little, MD (1) · Annamaria AL Colao, Prof. (1) · Bing Xing, MD (1) · Daniel F Kelly, MD (1) · David M Kleinberg, MD (1) · James Evans, MD (1) · Jana Ivanidze, MD/Ph.D (1) · Juan C Pedemonte, MD (1) · Lulu Ma, MD (1) · Pablo Villanueva, MD (1) · Saipin Muangman, physician (1)
PMID 10469005, PMID 10690849, PMID 10999798, PMID 11397887, PMID 12843148, PMID 14764779, PMID 15070920, PMID 15613435, PMID 15827109, PMID 15886238, PMID 15886256, PMID 16373932, PMID 16449332, PMID 16487447, PMID 16537687, PMID 17984237, PMID 25293480, PMID 25493927, PMID 26229757, PMID 26329913, PMID 28298041, PMID 35275019, PMID 35661809, PMID 38553990, PMID 3899825, PMID 40760415, PMID 42046793, PMID 5427331, PMID 8050136, PMID 8327647, PMID 8514973, PMID 9709939, PMID 9768640, PMID 9768641, PMID 9808008