3 completed, 3 recruiting, 1 terminated, 1 unknown. 3 Phase 3, 1 Not applicable, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3 | Completed 2, Recruiting 1 |
| Not applicable | 1 | Unknown 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 4 | 1 | Terminated 1 |
Follow Gigantism: new trials by email Literature Review of Gigantism trials Research Report on Gigantism
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acromegaly Previously Treated With Somatostatin Analogs Debio 4126, Placebo - Acromegaly | Phase 3 | Recruiting | Debiopharm International SA | 119 | 2025-11-26 | 2026-10-23 |
| Safety and Efficacy of Pegvisomant in Children With Growth Hormone Excess Pegvisomant - Pituitary Disease | Phase 3 | Completed | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 12 | 2019-10-21 | 2025-11-06 |
| Pasireotide in Patients With Acromegaly Inadequately Controlled With First Generation Somatostatin Analogues Pasireotide LAR - Acromegaly | Phase 3 | Completed | Novartis Pharmaceuticals | 123 | 2015-03-31 | 2019-12-10 |
| Interdisciplinary Pituitary Disorders Centre of Excellence: Assessment of Patient Education Tools Educational Intervention - Pituitary Neoplasms, Prolactinoma | Not applicable | Unknown | Unity Health Toronto | 60 | 2014-02-01 | 2015-07-31 |
| A Pilot Study of Pre- and Post-operative Use of Somatuline Depot. lanreotide - Acromegaly | Phase 4 | Terminated | Saint John's Cancer Institute | 4 | 2013-05-01 | 2021-09-30 |
| Efficacy and Safety of Pasireotide LAR (Long-acting Release) in Japanese Patients With Acromegaly or Pituitary Gigantism Pasireotide LAR - Acromegaly, Pituitary Gigantism | Phase 2 | Completed | Novartis Pharmaceuticals | 33 | 2012-10-16 | 2019-09-16 |
| Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA Acromegaly, Gigantism | Recruiting | Barts & The London NHS Trust | 10000 | 2007-03-01 | 2026-05-20 | |
| An Investigation of Pituitary Tumors and Related Hypothalmic Disorders Tissue specimen collection, MRI - Panhypopituitarism, Gigantism/Acromegaly | Recruiting | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 2000 | 1997-04-21 | 2026-10-19 |
Acromegaly (6) · Pituitary Neoplasms (4) · Growth Disorders (2) · Pituitary Diseases (2) · Prolactinoma (2) · ACTH-Secreting Pituitary Adenoma (1) · Carcinogenesis (1) · Combined Pituitary Hormone Deficiency (1) · Congenital Abnormalities (1) · Growth Hormone-Secreting Pituitary Adenoma (1) · Pituitary ACTH Hypersecretion (1) · Pituitary Adenoma, Familial Isolated (1)
Bone Diseases (8) · Bone Diseases, Developmental (8) · Bone Diseases, Endocrine (8) · Brain Diseases (8) · Central Nervous System Diseases (8) · Endocrine System Diseases (8) · Hyperpituitarism (8) · Hypothalamic Diseases (8) · Musculoskeletal Diseases (8) · Nervous System Diseases (8) · Pituitary Diseases (6) · Endocrine Gland Neoplasms (5) · Neoplasms (5) · Neoplasms by Site (5) · Brain Neoplasms (4)
pasireotide (2) · Early Intervention, Educational (1) · Tissue Banks (1) · lanreotide (1) · pegvisomant (1)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (2) · Novartis Pharmaceuticals (2) · Barts & The London NHS Trust (1) · Debiopharm International SA (1) · Saint John's Cancer Institute (1) · Unity Health Toronto (1)
United States (4) · United Kingdom (3) · Belgium (2) · Brazil (2) · Bulgaria (2) · France (2) · Hungary (2) · Italy (2) · Romania (2) · Argentina (1) · Austria (1) · Canada (1) · China (1) · Colombia (1) · Denmark (1)
Daniel F Kelly, MD (1) · Deborah P Merke, M.D. (1) · Karim A Calis, Pharm.D. (1) · Marta Korbonits, MD PhD (1) · Michael Cusimano, MD, PhD (1)
PMID 19170709, PMID 19344074, PMID 21208107, PMID 22154461, PMID 24412141, PMID 25258026, PMID 27253664, PMID 27496264, PMID 29395172, PMID 30234410, PMID 32117045, PMID 32232325, PMID 32714280, PMID 36149413, PMID 40813536, PMID 41349930, PMID 41540017
2014 (1)