15 completed, 6 recruiting, 4 terminated, 3 unknown. 10 Phase 3, 9 Phase 2, 4 Not applicable, 3 Phase 1, 3 Phase 4.
Follow Sulfamethoxazole: new trials by email Literature Review of Sulfamethoxazole trials Research Report on Sulfamethoxazole
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prophylactic Antibiotics for Outpatient Urethral Bulking Bactrim (800/160 mg), Keflex (500 mg), Cipro (250 mg), or Macrobid (100mg) - Urinary Tract Infections, Stress Urinary Incontinence | Phase 4 | Recruiting | University of Miami | 150 | 2026-08-01 | 2026-08-20 |
| Efficacy and Safety of Tamsulosin for Children with Posterior Urethral Valve. Tamsulosin, Oxybutynin, Trimethoprim/sulfamethoxazole (TMP/SMZ) - Posterior Urethral Valve | Phase 3 | Recruiting | Mansoura University | 50 | 2024-11-01 | 2024-12-20 |
| Pivmecillinam With Amoxicillin/Clavulanic Acid for Step Down Oral Therapy in ESBL UTIs Pivmecillinam and amoxicillin/clavulanic acid, Standard treatment, ciprofloxacin, trimethoprim/sulfamethoxazole or ertapenem depending on susceptibility - Urinary Tract Infections, Bacteremia | Phase 3 | Recruiting | Lund University | 330 | 2023-05-29 | 2023-08-28 |
| Single Dose Aminoglycosides for Acute Uncomplicated Cystitis in the Emergency Department Setting Gentamicin, Standard of Care - Urinary Tract Infections | Phase 2 | Unknown | Mercy Health Ohio | 160 | 2022-10-01 | 2023-01-27 |
| Oral Antimicrobial Treatment vs. Outpatient Parenteral for Infective Endocarditis Cefaclor, Ciprofloxacin Tablets, Ciprofloxacin Injection - Endocarditis Infective | Phase 4 | Recruiting | Fundacion Clinic per a la Recerca Biomédica | 360 | 2022-08-17 | 2026-07-07 |
| Fluoroquinolone Associated Disability Fluoroquinolone (FQ), Azithromycin (AZ), Sulfamethoxazole/Trimethoprim (ST) Fixed Dose Combination - Bronchitis, Sinusitis | Completed | Janssen Research & Development, LLC | 239306 | 2018-05-17 | 2019-01-29 | |
| Comparison of Topical Therapies in Post op Endoscopic Sinus Surgery Patients Saline Nasal, Budesonide Nasal, Topical Antibacterial (Product) - Chronic Rhinosinusitis (Diagnosis) | Phase 3 | Withdrawn | University of Florida | 2018-04-01 | 2018-03-30 | |
| Prophylactic Oral Antibiotics on Sinonasal Outcomes Following Endoscopic Transsphenoidal Surgery for Pituitary Lesions Placebo, Oral Antibiotics cefdinir or trimethoprim/sulfamethoxazole - Antibiotics, Pituitary Adenoma | Phase 4 | Recruiting | St. Joseph's Hospital and Medical Center, Phoenix | 116 | 2017-07-01 | 2018-08-15 |
| A Non-Interventional Safety Study of Balsamic Bactrim Guaifenesin, Sulfamethoxazole, Trimethoprim - Bronchitis | Completed | Hoffmann-La Roche | 52 | 2016-11-15 | 2017-11-07 | |
| A Safety Study of Balsamic Bactrim in Pediatric Participants With Acute Bronchitis Guaifenesin, Sulfamethoxazole, Trimethoprim - Bronchitis | Completed | Hoffmann-La Roche | 51 | 2016-11-10 | 2019-12-13 | |
| Sulfamethoxazole for the Treatment of Primary PREPL Deficiency Sulfamethoxazole - Hypotonia Cystinuria Syndrome, Isolated PREPL Deficiency | Phase 2 | Unknown | Universitair Ziekenhuis Brussel | 15 | 2015-10-01 | 2015-12-29 |
| Reducing the Burden of Malaria in HIV-Infected Pregnant Women and Their HIV-Exposed Children (PROMOTE-BC2) Monthly dihydroartemisinin-piperaquine (DP) + daily trimethoprim/sulfamethoxazole (TS), Monthly placebo + daily trimethoprim/sulfamethoxazole (TS) - Malaria, Human Immunodeficiency Virus | Phase 3 | Completed | University of California, San Francisco | 200 | 2014-12-09 | 2019-03-05 |
| Efficacy of Oral Antibiotic Therapy Compared to Intravenous Antibiotic Therapy for Osteomyelitis Intravenous Antibacterial Agent, Oral Antibacterial Agent - Osteomyelitis | Phase 2 | Terminated | Loyola University | 30 | 2014-03-19 | 2018-07-19 |
| Patients Response to Early Switch To Oral:Osteomyelitis Study oral antibiotics, intravenous antibiotics - Osteomyelitis | Early Phase 1 | Terminated | Julio Ramirez | 11 | 2014-03-06 | 2021-04-06 |
| Efficacy and Safety Study of Antibiotic Treatment to Treat Hip Prosthetic Joint Infection VANCOMYCIN, CEFTRIAXONE, CLINDAMYCIN - Hip Prosthetic Joint Infection | Phase 2 | Unknown | University Hospital, Tours | 100 | 2012-10-01 | 2014-05-28 |
| Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections) Ceftazidime - Avibactam ( CAZ-AVI), Doripenem, Either switch to oral therapy: 500 mg of Ciprofloxacin (oral) - Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis | Phase 3 | Completed | Pfizer | 598 | 2012-10-01 | 2017-09-06 |
| Persistent Methicillin Resistant Staphylococcus Aureus Eradication Protocol (PMEP) Inhaled Vancomycin, Placebo (Sterile Water), Rifampin - Cystic Fibrosis | Phase 2 | Completed | Johns Hopkins University | 29 | 2012-10-01 | 2019-02-26 |
| Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections) Ceftazidime - Avibactam ( CAZ-AVI), Doripenem, Either switch to oral therapy: 500 mg of Ciprofloxacin (oral) - Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis | Phase 3 | Completed | Pfizer | 641 | 2012-10-01 | 2017-09-06 |
| Effects of Treatments on Atopic Dermatitis Trimethoprim/sulfamethoxazole (TMP/SMZ), Cephalexin, Doxycycline - Eczema, Dermatitis | Phase 2 | Recruiting | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | 130 | 2012-09-18 | 2026-09-28 |
| D Mannose in Recurrent Urinary Tract Infections D Mannose, trimethoprim/sulfamethoxazole - Recurrent Urinary Tract Infection | Phase 3 | Completed | Fondazione IRCCS Policlinico San Matteo di Pavia | 60 | 2012-01-01 | 2014-05-21 |
Showing 20 of 31. Sign in to see all of them.
Urinary Tract Infections (5) · Acquired Immunodeficiency Syndrome (4) · HIV Infections (4) · Pneumonia, Pneumocystis (4) · Bronchitis (3) · AIDS-Related Opportunistic Infections (2) · Infections (2) · Multiple Myeloma (2) · Osteomyelitis (2) · Abscess (1) · Bacteremia (1) · Blast Crisis (1) · Burkitt Lymphoma (1) · Chorioretinitis (1) · Congenital Abnormalities (1)
Hoffmann-La Roche (2) · Pfizer (2) · Fondazione IRCCS Policlinico San Matteo di Pavia (1) · Fundacion Clinic per a la Recerca Biomédica (1) · Gary Morrow (1) · International Maternal Pediatric Adolescent AIDS Clinical Trials Group (1) · Jacobus Pharmaceutical (1) · Janssen Research & Development, LLC (1) · Johns Hopkins University (1) · Julio Ramirez (1) · Lederle Laboratories (1) · Loyola University (1) · Lund University (1) · M.D. Anderson Cancer Center (1) · Mansoura University (1)
United States (18) · Italy (4) · Peru (4) · Germany (3) · Spain (3) · Argentina (2) · Brazil (2) · Bulgaria (2) · Croatia (2) · Czechia (2) · Israel (2) · Mexico (2) · Poland (2) · Romania (2) · Russia (2)
Paul Newell, MBBS, MRCP (2) · Ahmed Elkashef (1) · Andrew Little, MD (1) · Ashraf Tarek Hafez (1) · Charles D. Mitchell, MD (1) · Claire Pomeroy, MD (1) · Daniele Porru, MD (1) · David Seligson, MD (1) · Diane V Havlir, MD (1)
PMID 27313268, PMID 29912399, PMID 30061279, PMID 30221827, PMID 30832720, PMID 32602065, PMID 12095806, PMID 15257060, PMID 15276398, PMID 15840453, PMID 17005949, PMID 18230259, PMID 18702902, PMID 19128645, PMID 19588358, PMID 20607114, PMID 20876410, PMID 21732834, PMID 22311838, PMID 22530208, PMID 22980682, PMID 23438305, PMID 23776108, PMID 24119597, PMID 24868146, PMID 25832968, PMID 26363164, PMID 26872154, PMID 27440128, PMID 27466854, PMID 27556896, PMID 27614925, PMID 27717402, PMID 28124652, PMID 28329368, PMID 28480292, PMID 29029337, PMID 29272443, PMID 29654388, PMID 30530597, PMID 33020153, PMID 36041061, PMID 36511181, PMID 37660037, PMID 37700689, PMID 39324693, PMID 40024946, PMID 4902833, PMID 8948280
U01AI068632 (1), U10CA037420 (1)