92 completed, 63 recruiting, 24 unknown, 19 terminated. 78 Phase 2, 52 Not applicable, 51 Phase 1, 10 Phase 3, 7 Early Phase 1.
Follow Meningioma: new trials by email Literature Review of Meningioma trials Research Report on Meningioma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of ONC201 for Refractory Meningioma ONC201 - Meningioma, Refractory Meningioma | Phase 2 | Withdrawn | University of Nebraska | 2026-12-01 | 2026-01-26 | |
| China Treatment Trial for Tumor in Sellar Region With Unruptured Intracranial Aneurysm Tumor resection followed by aneurysm treatment, Aneurysm treatment followed by tumor resection, Observation - Unruptured Intracranial Aneurysms, Pituitary Neuroendocrine Tumor | Active not recruiting | Cheng sen | 608 | 2026-10-20 | 2026-10-21 | |
| Preoperative Embolization for Highly Vascular Brain Tumors Preoperative Endovascular Embolization - Brain Neoplasms, Meningioma | Not applicable | Not yet recruiting | Assiut University | 55 | 2026-10-01 | 2026-09-17 |
| Pharmacoscopy for Patients With Refractory Primary Brain Tumors Pharmacoscopy 1.0 - Brain (Nervous System) Cancers, Glioblastoma | Phase 2 | Recruiting | University of Zurich | 40 | 2026-09-11 | 2026-09-21 |
| IN10018 in Combination With Dalpiciclib for Progressive Meningiomas Ifebemtinib, Dalpiciclib - Meningioma, CDK4/6 Inhibitor | Phase 1 | Recruiting | Capital Medical University | 24 | 2026-08-31 | 2026-10-21 |
| Direct Comparison of Ga-68-DOTATATE and Ga-68-DOTATOC Ga-68- DOTATATE, Ga-68-DOTATOC - Meningioma | Phase 2 | Withdrawn | Weill Medical College of Cornell University | 2026-08-01 | 2026-08-31 | |
| Luvometinib in Combination With Serplulimab for NF2-Related Tumors Luvometinib, Serplulimab - NF2-related Schwannomatosis, NF2 | Phase 1 / Phase 2 | Not yet recruiting | Beijing Tiantan Hospital | 30 | 2026-07-31 | 2026-07-16 |
| DEXmedetomidine for Postoperative Analgesia and Delirium Prevention After NEUROsurgery (DEX-NEURO Trial) Dexmedetomidine, Normal Saline (0.9% NaCl) - Neurosurgery, Brain Cancer | Not applicable | Not yet recruiting | University of Malaya | 60 | 2026-07-22 | 2026-02-09 |
| Platform Research for Innovative Medicines in NF2-SWN (PRIME-NF2) Selumetinib 25mg/m2, Luvometinib, Serplulimab - Neurofibromatosis Type 2, Vestibular Schwannoma | Phase 2 | Not yet recruiting | Beijing Tiantan Hospital | 200 | 2026-07-18 | 2026-07-20 |
| A Study of JZP3507 (ONC206) in Recurrent Grade 2 or 3 Meningioma JZP3507 - Meningioma | Phase 2 | Recruiting | Jazz Pharmaceuticals | 30 | 2026-07-16 | 2026-07-30 |
| Selumetinib for NF2-Related Schwannomatosis Selumetinib - Neurofibromatosis Type 2, NF2 | Phase 2 | Not yet recruiting | Beijing Tiantan Hospital | 20 | 2026-07-15 | 2026-07-16 |
| Search for Circulating Tumour Cells in the Blood and/or Cerebrospinal Fluid in Patients With Recurrent Aggressive Meningiomas: Proof-of-concept Study Blood sampling, Lumbar puncture - Meningioma | Not applicable | Recruiting | University Hospital, Montpellier | 15 | 2026-07-13 | 2026-07-14 |
| Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical Procedures Panitumumab-IRDye800 - Meningioma, Glioblastoma | Early Phase 1 | Recruiting | Eben Rosenthal | 30 | 2026-07-07 | 2026-10-16 |
| Diagnostic Performance and Quantitative Analysis of [18F]FET PET in Brain Tumours Brain Tumors | Not yet recruiting | IRCCS San Raffaele | 69 | 2026-06-01 | 2026-05-20 | |
| A Study of Zanzalintinib in Participants With Recurrent or Progressive Meningioma Zanzalintinib - Meningioma | Phase 2 | Recruiting | Exelixis | 100 | 2026-05-21 | 2026-10-06 |
| NK Cell Therapy for Malignant Solid Brain Tumors Autologous NK cells - Malignant Solid Brain Tumors, Glioblastoma (GBM) | Not applicable | Recruiting | Peking University Third Hospital | 27 | 2026-04-01 | 2026-04-27 |
| Measurement of PSMA Expression in Vivo in Recurrent Meningiomas by PET Imaging: a Preliminary Study to a Therapeutic Trial Using Radioligand Therapy (RLT) PET PSMA - Meningioma | Not applicable | Not yet recruiting | Hospices Civils de Lyon | 40 | 2026-03-01 | 2026-02-23 |
| Analysis of Cerebrospinal Fluid Leakage After Surgery for Intracranial Tumors Brain Tumor Adult, Brain Tumor Benign | Recruiting | Medical University of Warsaw | 200 | 2026-02-03 | 2026-05-22 | |
| Psychometric Validation of the MQOL-FR and Descriptive Assessment of Quality of Life in Patients With Meningiomas Quality-of-life questionnaire administration - Intracranial Meningioma, Meningioma | Not yet recruiting | Centre Hospitalier St Anne | 238 | 2026-02-02 | 2026-02-03 | |
| Comparison of Skin Closure Techniques in Oncological Neurosurgical Procedures: Intradermal Running Suture Versus Transdermal Interrupted Sutures Absorbable running intradermal suture, Non-absorbable interrupted transdermal suture - Brain Tumor Adult, Brain Tumor Benign | Not applicable | Recruiting | Medical University of Warsaw | 382 | 2026-02-01 | 2026-05-20 |
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Brain Neoplasms (97) · Glioma (69) · Astrocytoma (56) · Glioblastoma (55) · Oligodendroglioma (52) · Ependymoma (49) · Medulloblastoma (46) · Central Nervous System Neoplasms (42) · Gliosarcoma (34) · Choroid Plexus Neoplasms (31) · Craniopharyngioma (31) · Pinealoma (31) · Neuroectodermal Tumors, Primitive (30) · Glioma, Subependymal (23)
Neoplasms by Histologic Type (239) · Neoplasms by Site (239) · Neoplasms, Nerve Tissue (239) · Neoplasms, Vascular Tissue (239) · Nervous System Diseases (239) · Meningeal Neoplasms (238) · Nervous System Neoplasms (238) · Neoplasms (216) · Central Nervous System Neoplasms (197) · Central Nervous System Diseases (119) · Neuroectodermal Tumors (119) · Brain Diseases (115) · Neoplasms, Germ Cell and Embryonal (114) · Neoplasms, Glandular and Epithelial (103) · Neoplasms, Neuroepithelial (99)
Magnetic Resonance Spectroscopy (16) · Bevacizumab (7) · Everolimus (7) · Hydroxyurea (6) · Proton Therapy (6) · Radiosurgery (6) · gallium Ga 68 dotatate (6) · lutetium Lu 177 dotatate (6) · Specimen Handling (5) · 2-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole (4) · Cyclophosphamide (4) · Imatinib Mesylate (4) · Observation (4) · Radiotherapy (4) · Surgical Procedures, Operative (4)
National Cancer Institute (NCI) (12) · Wake Forest University Health Sciences (7) · Beijing Tiantan Hospital (6) · Central Hospital, Nancy, France (6) · Massachusetts General Hospital (5) · Northwestern University (4) · Weill Medical College of Cornell University (4) · Case Comprehensive Cancer Center (3) · City of Hope Medical Center (3) · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta (3) · Memorial Sloan Kettering Cancer Center (3) · NYU Langone Health (3) · National Institutes of Health Clinical Center (CC) (3) · SWOG Cancer Research Network (3) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (3)
United States (129) · France (23) · China (16) · Germany (8) · Switzerland (8) · Canada (7) · Italy (7) · Netherlands (4) · India (3) · Norway (3) · Thailand (3) · United Kingdom (3) · Australia (2) · Austria (2) · Belgium (2)
Edward G. Shaw, MD (3) · Thomas Kaley, MD (3) · Alexander Dmitriev, MD (2) · Anhua Wu, MD (2) · Danielle Eekers (2) · Darell D. Bigner, MD, PhD (2) · Harry T Whelan, MD (2) · Helen A Shih, MD (2) · Howard A. Fine, MD (2) · Jana Ivanidze, MD/Ph.D (2) · Jana Portnow, MD (2) · M. Sue O'Dorisio, MD, PhD (2) · Nader Sanai, MD (2) · Patrick Y. Wen, MD (2) · Priscilla Brastianos, MD (2)
PMID 11273919, PMID 11410496, PMID 11810123, PMID 14750917, PMID 16127110, PMID 16549835, PMID 16914578, PMID 18056189, PMID 18470481, PMID 18633018, PMID 18728566, PMID 21062428, PMID 21850464, PMID 21938530, PMID 22480131, PMID 22752346, PMID 23845268, PMID 24327518, PMID 24570753, PMID 26261748, PMID 26428319, PMID 26493095, PMID 26635088, PMID 26746334, PMID 26943915, PMID 27020837, PMID 27413488, PMID 27424289, PMID 28053024, PMID 28570730, PMID 28672195, PMID 28984517, PMID 29383130, PMID 29846250, PMID 30215565, PMID 31101621, PMID 31533931, PMID 31786276, PMID 31831767, PMID 31832214, PMID 31882719, PMID 32000819, PMID 33068429, PMID 33235996, PMID 34127830, PMID 34667843, PMID 35110315, PMID 35275019, PMID 35289329, PMID 35417530
U01CA062399 (3), U10CA032102 (3), U10CA081851 (3), P30CA033572 (2), P30CA043703 (2), P30CA138292 (2), R01CA167632 (2), 2005 (1), 2009 (1), 2014 (1), 2019 (1), N01CM62202 (1), P01CA118816 (1), P30CA008748 (1), P30CA014089 (1)