2 active not recruiting, 2 completed, 1 unknown. 2 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 2 | Completed 2 |
| Phase 3 | 1 | Active not recruiting 1 |
Follow Hypercalciuric Hypocalcemia, Familial: new trials by email Literature Review of Hypercalciuric Hypocalcemia, Familial trials Research Report on Hypercalciuric Hypocalcemia, Familial
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Encaleret Compared to Standard of Care in Participants With ADH1 Encaleret, Standard of Care - Autosomal Dominant Hypocalcemia (ADH) | Phase 3 | Active not recruiting | Calcilytix Therapeutics, Inc., a BridgeBio company | 67 | 2023-01-06 | 2026-07-29 |
| ADH1 and ADH2 Disease Monitoring Study (DMS) Autosomal Dominant Hypocalcemia | Active not recruiting | Calcilytix Therapeutics, Inc., a BridgeBio company | 95 | 2022-01-20 | 2026-04-30 | |
| Safety, Tolerability, and Efficacy of Encaleret in Participants With Autosomal Dominant Hypocalcemia (ADH) Type 1 Encaleret - Autosomal Dominant Hypocalcemia (ADH), Autosomal Dominant Hypocalcemia Type 1 (ADH1) | Phase 2 | Completed | Calcilytix Therapeutics, Inc., a BridgeBio company | 13 | 2020-09-20 | 2024-11-19 |
| A Study to Determine the Effects of NPSP795 on the Calcium-sensing Receptor in Subjects With Autosomal Dominant Hypocalcemia as Measured by PTH Levels and Blood Calcium Concentrations NPSP795 - Autosomal Dominant Hypocalcemia (ADH) | Phase 2 | Completed | Shire | 7 | 2014-07-18 | 2021-08-09 |
| Characterization of Patients With Non-surgical Hypoparathyroidism and Pseudohypoparathyroidism Idiopathic Hypoparathyroidism, Autosomal Dominant Hypocalcaemia | Unknown | University of Aarhus | 100 | 2014-06-01 | 2018-08-07 |
Hypoparathyroidism (4) · Hypocalcemia (3) · Calcium Metabolism Disorders (2) · Hypercalciuria (2) · Metabolic Diseases (2) · Muscular Diseases (2) · Musculoskeletal Abnormalities (2) · Musculoskeletal Diseases (2) · Nephrocalcinosis (2) · Nephrolithiasis (2) · Pseudohypoparathyroidism (1)
Endocrine System Diseases (4) · Nutritional and Metabolic Diseases (4) · Parathyroid Diseases (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Water-Electrolyte Imbalance (3) · Calcinosis (2) · Calcium Metabolism Disorders (2) · Congenital Abnormalities (2) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Kidney Diseases (2) · Male Urogenital Diseases (2) · Metabolic Diseases (2) · Nervous System Diseases (2) · Neuromuscular Diseases (2)
Standard of Care (1)
Calcilytix Therapeutics, Inc., a BridgeBio company (3) · Shire (1) · University of Aarhus (1)
United States (4) · Denmark (3) · Australia (2) · Canada (2) · France (2) · Italy (2) · Japan (2) · Netherlands (2) · United Kingdom (2) · Belgium (1) · Czechia (1) · Finland (1) · Germany (1) · Portugal (1)