22 completed, 9 terminated, 3 recruiting, 2 active not recruiting. 38 Phase 2, 7 Phase 1, 6 Phase 3.
Follow Hyperphagia: new trials by email Literature Review of Hyperphagia trials Research Report on Hyperphagia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Choline Chloride for Injection in Adolescent and Adult Patients With Intestinal Failure Receiving Long Term Parenteral Support Choline Chloride for Injection, Placebo - Choline Deficiency, Liver Injury | Phase 2 / Phase 3 | Recruiting | Protara Therapeutics | 129 | 2025-12-10 | 2026-08-24 |
| A Study of Setmelanotide in Patients With Prader-Willi Syndrome Setmelanotide - Prader-Willi Syndrome, Obesity | Phase 2 | Active not recruiting | Rhythm Pharmaceuticals, Inc. | 18 | 2025-03-04 | 2026-02-12 |
| A Self-Guided Mobile Intervention for Adults With Binge Eating and Obesity Digital - Binge Eating Disorder Associated With Obesity, Binge Eating Disorder | Phase 1 / Phase 2 | Recruiting | Drexel University | 30 | 2025-02-01 | 2025-02-17 |
| Personalized Nutrition to Improve Recovery in Trauma Nutrition Supplement - Abdominal Trauma | Phase 2 | Recruiting | Duke University | 150 | 2024-04-12 | 2026-05-06 |
| A Study of the Effects of Oxytocin in Adults With Binge-eating Disorder TNX-1900 (Tonix Pharmaceuticals), Placebo - Binge-eating Disorder | Phase 2 | Active not recruiting | Massachusetts General Hospital | 60 | 2023-03-07 | 2026-11-12 |
| Oral Naltrexone In Pediatric Eating Disorders Naltrexone Hydrochloride, Control - Anorexia Nervosa/Bulimia, Anorexia in Adolescence | Phase 2 / Phase 3 | Terminated | Rosemary Claire Roden | 9 | 2022-04-22 | 2025-08-19 |
| Study of Tesomet With Open-label Extension in Subjects With Prader-Willi Syndrome Placebo, Tesomet - Prader-Willi Syndrome | Phase 2 | Withdrawn | Saniona | 2021-12-28 | 2022-12-13 | |
| Binge Eating & Birth Control Drospirenone-Ethinyl Estradiol Oral Tablet - Bulimia Nervosa, Binge Eating | Phase 2 | Terminated | University of North Carolina, Chapel Hill | 8 | 2020-09-24 | 2022-07-26 |
| Neurobiology of Bulimia Nervosa Estradiol, Micronized progesterone, Leuprolide Acetate - Bulimia Nervosa | Phase 2 | Completed | University of North Carolina, Chapel Hill | 10 | 2020-02-24 | 2022-07-26 |
| A Behavioral Activation Intervention Administered in a College Freshman Orientation Course behavioral activation - Alcohol; Use, Problem, Stress | Phase 2 | Completed | University of Kansas | 572 | 2019-09-05 | 2026-05-28 |
| Effects of Livoletide (AZP-531) on Food-related Behaviors in Patients With Prader-Willi Syndrome Livoletide, Placebo - Prader-Willi Syndrome, Hyperphagia | Phase 2 / Phase 3 | Terminated | Millendo Therapeutics SAS | 158 | 2019-03-25 | 2021-02-17 |
| Intensive Nutrition in Critically Ill Adults Supplemental parenteral nutrition - Critical Illness, Critically Ill | Phase 2 | Completed | Australian and New Zealand Intensive Care Research Centre | 240 | 2018-10-15 | 2024-05-24 |
| LIPIDS-P Trial Phase I/II Trial Smoflipid - Sepsis, Severe, Septic Shock | Phase 1 / Phase 2 | Completed | University of Florida | 59 | 2018-08-17 | 2025-08-11 |
| Lisdexamfetamine for Adults With Bulimia Nervosa Lisdexamfetamine dimesylate - Bulimia Nervosa | Phase 2 | Terminated | Aaron Keshen | 23 | 2018-06-21 | 2020-11-27 |
| Intranasal Oxytocin vs. Placebo for the Treatment of Hyperphagia in Prader-Willi Syndrome Intranasal Oxytocin (IN-OXT), Matched Placebo - Prader-Willi Syndrome, Hyperphagia | Phase 2 | Completed | Eric Hollander | 32 | 2018-04-11 | 2025-02-07 |
| Biology and Experience of Eating in Women With Obesity Naloxone, Placebo - Obesity | Phase 2 | Completed | University of California, San Francisco | 41 | 2017-05-20 | 2021-11-03 |
| SMOFlipid to Lessen the Severity of Neonatal Cholestasis SMOFlipid - Cholestasis, Jaundice, Obstructive | Phase 1 / Phase 2 | Terminated | University of Florida | 2 | 2016-05-01 | 2017-04-17 |
| Oxytocin vs. Placebo for the Treatment Hyperphagia in Children and Adolescents With Prader-Willi Syndrome Intranasal Oxytocin (IN-OXT), Matched Placebo - Prader-Willi Syndrome, Hyperphagia | Phase 2 | Completed | Montefiore Medical Center | 23 | 2015-10-01 | 2021-10-07 |
| Phase 2 Trial to Evaluate Safety and Efficacy of Setmelanotide (RM-493) in Obese Participants With Prader-Willi Syndrome Setmelanotide, Placebo - Prader-Willi Syndrome | Phase 2 | Completed | Rhythm Pharmaceuticals, Inc. | 40 | 2015-03-19 | 2023-07-27 |
| The Energy Dose Study Parenteral Nutrition, Propofol, Clevidipine - Critical Illness | Phase 2 | Terminated | Emory University | 12 | 2011-07-01 | 2022-06-10 |
Showing 20 of 38. Sign in to see all of them.
Bulimia (16) · Obesity (8) · Binge-Eating Disorder (7) · Bulimia Nervosa (6) · Prader-Willi Syndrome (6) · Feeding and Eating Disorders (4) · Cholestasis (3) · Mental Disorders (3) · Alcoholism (2) · Critical Illness (2) · Cross Infection (2) · Intestinal Failure (2) · Liver Diseases (2) · Abdominal Injuries (1)
Pathological Conditions, Signs and Symptoms (38) · Signs and Symptoms (38) · Signs and Symptoms, Digestive (38) · Nutritional and Metabolic Diseases (15) · Nutrition Disorders (14) · Overnutrition (12) · Mental Disorders (11) · Overweight (11) · Body Weight (8) · Digestive System Diseases (8) · Feeding and Eating Disorders (8) · Pathologic Processes (7) · Abnormalities, Multiple (6) · Chromosome Disorders (6)
Cognitive Behavioral Therapy (3) · Parenteral Nutrition (3) · fish oil triglycerides (3) · Choline (2) · Oxytocin (2) · SMOFlipid (2) · Sugars (2) · setmelanotide (2) · Bupropion (1) · ClinOleic (1) · Enteral Nutrition (1) · Estradiol (1) · Fat Emulsions, Intravenous (1) · Fish Oils (1) · Injections (1)
University of North Carolina, Chapel Hill (3) · Emory University (2) · Rhythm Pharmaceuticals, Inc. (2) · University of Florida (2) · Washington University School of Medicine (2) · Aaron Keshen (1) · Australian and New Zealand Intensive Care Research Centre (1) · B. Braun Melsungen AG (1) · CONKO-Studiengruppe (1) · Drexel University (1) · Duke University (1) · Eric Hollander (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · Insel Gruppe AG, University Hospital Bern (1) · Kaiser Permanente (1)
United States (30) · Canada (3) · Germany (3) · Australia (2) · Belgium (2) · France (2) · Denmark (1) · Italy (1) · Netherlands (1) · New Zealand (1) · Poland (1) · Spain (1) · Switzerland (1) · United Kingdom (1)
Denise E Wilfley, Ph.D. (2) · Eric Hollander, MD (2) · Jessica Baker, PhD (2) · Aaron Keshen, MD, FRCPC (1) · Ashley E Mason, PhD (1) · Berthold V. Koletzko, Prof., MD (1) · Daniel Le Grange, PhD (1) · David F Mercer, MD, PhD (1) · David Meeker (1) · David Meeker, MD (1) · Elizabeth A Lawson, MD (1) · Emma Ridley, PhD (1) · Faheem W Guirgis, MD (1) · Guillermo Umpierrez, MD (1)
PMID 12150647, PMID 20214798, PMID 22136963, PMID 22282429, PMID 22488002, PMID 23201707, PMID 23656848, PMID 23751236, PMID 23894176, PMID 23909727, PMID 25240070, PMID 26210388, PMID 26838529, PMID 27808536, PMID 28521607, PMID 29607525, PMID 29924393, PMID 30411372, PMID 30900274, PMID 31537565, PMID 31982647, PMID 32072161, PMID 33315720, PMID 33392541, PMID 33534199, PMID 35260448, PMID 36167287, PMID 36833579, PMID 37218020, PMID 37583941, PMID 38488429, PMID 39716214, PMID 39762887
K23DK071646 (1), R01AA027791 (1), R21DK089369 (1), R21MH121726 (1), R41MH134704 (1)