13 completed, 3 unknown, 2 not yet recruiting, 2 terminated. 9 Not applicable, 5 Phase 4, 3 Phase 2, 3 Phase 3, 1 Early Phase 1.
Follow Fat Emulsions, Intravenous: new trials by email Literature Review of Fat Emulsions, Intravenous trials Research Report on Fat Emulsions, Intravenous
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 2 Study of Methylene Blue Photodynamic Therapy for Treatment of Breast Abscesses Standard of care breast abscess drainage, Methylene Blue, Lipid Emulsion - Breast Abscess | Phase 2 | Not yet recruiting | University of Rochester | 50 | 2027-07-01 | 2026-08-19 |
| Efficacy of Methylene Blue Photodynamic Therapy for Treatment of Deep Tissue Abscesses Methylene Blue, Lipid Emulsion, Insertion of optical fiber - Abscess | Phase 2 | Not yet recruiting | University of Rochester | 120 | 2026-07-15 | 2026-02-10 |
| Effects of Lipid Emulsions on Coagulation Lipid Emulsion - Coagulation Disorder, Coagulation Function | Completed | Mimi Tang, PhD | 6259 | 2025-05-23 | 2026-03-13 | |
| Does Intralipid Infusion Can Reverse the Spinal Anesthesia Effect in Day Case Surgery? Lipid emulsion - Intralipid Infusion, Spinal Anesthesia | Not applicable | Completed | Benha University | 200 | 2025-02-01 | 2025-12-08 |
| Hepatic Mitochondrial Metabolism in Fatty Liver Disease in Humans 13C-α-Ketoisocaproic Acid Breath Test, Ethanol, Lipid Emulsion - Non-alcoholic Fatty Liver Disease NAFLD | Not applicable | Enrolling by invitation | Helsinki University Central Hospital | 12 | 2024-09-01 | 2024-08-19 |
| Assessing The Role Of Intravenous Lipid Emulsion As A Life Saving Therapy In Pesticides Toxicity Lipid Emulsion, Intravenous, Atropine, Toxogonin - Pesticide Poisoning | Phase 4 | Unknown | Aya Sabry Mohamed Mohamed | 62 | 2022-12-01 | 2022-08-16 |
| Role of Intravenous Lipid Emulsion in Improving Coma of Acute Antipsychotics Poisoning Intravenous Lipid Emulsion (Intralipid 20%) - Coma | Not applicable | Unknown | Ain Shams University | 30 | 2021-03-10 | 2021-03-19 |
| Lipoproteins and ImmunoMetabolism Lipid Emulsion - Obesity, Metabolic Syndrome | Not applicable | Unknown | University of Seville | 40 | 2020-02-01 | 2023-02-27 |
| Early Higher Intravenous Lipid Intake in VLBW Infants Intravenous lipid emulsion - Very Low Birth Weight Infant | Not applicable | Completed | Belal Alshaikh | 83 | 2018-08-15 | 2021-12-21 |
| Fat Emulsion in Preventing Hypersensitivity Reactions in Patients With Cancer Receiving Carboplatin or Oxaliplatin Fat Emulsion, Placebo - Advanced Malignant Neoplasm | Not applicable | Completed | Mayo Clinic | 19 | 2017-07-14 | 2024-12-17 |
| Effects of Lipid Emulsion on the Pharmacokinetic and Pharmacodynamic Properties of Metoprolol. metoprolol, intravenous lipid emulsion, Sodium chloride 0.9% solution - lipid emulsion dummy - Drug Overdose, Overdose of Beta-adrenergic Blocking Drug | Phase 4 | Completed | Mikkel Bring Christensen | 10 | 2016-09-01 | 2017-04-12 |
| Digestion of Biopolymer Based Lipid Emulsions Lipid emulsion - Healthy | Not applicable | Completed | University of Zurich | 21 | 2016-03-01 | 2016-10-05 |
| Lipid Emulsions and Liver Function - Results After 5 Years. Intravenous Lipid Emulsion - Liver Failure, Parenteral Nutrition-Related Hepatitis | Phase 4 | Completed | Stanley Dudrick's Memorial Hospital | 65 | 2016-01-01 | 2020-04-17 |
| Phase 3 Study to Compare Safety and Efficacy of Smoflipid 20% to Intralipid 20% in Hospitalized Neonates and Infants Smoflipid 20% (investigational lipid for parenteral nutrition), Intralipid® 20% - Hospitalized Neonates and Infants, Expected to Require Parenteral Nutrition for 28 Days | Phase 3 | Terminated | Fresenius Kabi | 204 | 2015-12-01 | 2022-01-05 |
| To Study the Effects of Lipid Emulsion on Hemodynamics in Organophosphate Compound Poisoning Lipid Emulsion - Organophosphate Poisoning | Phase 4 | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 40 | 2015-09-01 | 2018-06-21 |
| Quantitative MR Methods for Lipid Emulsions Lipid emulsion - Healthy | Early Phase 1 | Completed | University of Zurich | 22 | 2014-08-01 | 2015-04-09 |
| Prospective Randomized Clinical Trial of Intravenous Lipids and Cholestasis intravenous lipid - Parenteral Nutrition Associated Cholestasis | Phase 3 | Completed | University of Rochester | 40 | 2012-02-01 | 2020-12-03 |
| Parenteral Lipid Emulsions and the Liver Function Lipid Emulsions, Intravenous - Liver Failure | Phase 4 | Completed | Stanley Dudrick's Memorial Hospital | 64 | 2010-04-01 | 2017-02-07 |
| Low Dose Parenteral Fat for Prevention of Parenteral Nutrition Associated Cholestasis in Preterm Neonates Intravenous fat emulsion, Restriction of intravenous fat emulsion to 1 gm/kg/d - Parenteral Nutrition-Associated Liver Disease | Not applicable | Completed | Yale University | 136 | 2009-06-01 | 2014-10-28 |
| Study Comparing a Soybean Oil-Based With an Olive Oil-Based Lipid Emulsion in ICU Patients Requiring TPN ClinOleic 20% Intravenous Emulsion, Intralipid, 20% Intravenous Emulsion - Parenteral Nutrition | Phase 2 / Phase 3 | Completed | Emory University | 100 | 2008-11-01 | 2018-10-17 |
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Hyperphagia (2) · Liver Failure (2) · Abscess (1) · Coma (1) · Cross Infection (1) · Drug Overdose (1) · Hemostatic Disorders (1) · Hyperglycemia (1) · Hypertriglyceridemia (1) · Inflammation (1) · Insulin Resistance (1) · Metabolic Diseases (1) · Metabolic Syndrome (1) · Obesity (1) · Organophosphate Poisoning (1)
University of Rochester (3) · Stanley Dudrick's Memorial Hospital (2) · University of Zurich (2) · Ain Shams University (1) · Aya Sabry Mohamed Mohamed (1) · Belal Alshaikh (1) · Benha University (1) · Emory University (1) · Fresenius Kabi (1) · Helsinki University Central Hospital (1) · Mayo Clinic (1) · Mikkel Bring Christensen (1) · Mimi Tang, PhD (1) · OSF Healthcare System (1) · Post Graduate Institute of Medical Education and Research, Chandigarh (1)
United States (8) · Egypt (3) · Poland (2) · Switzerland (2) · Canada (1) · China (1) · Denmark (1) · Finland (1) · India (1) · Spain (1)
Aminah Jatoi, M.D. (1) · Ashwani K Sharma, MD (1) · Belal Alshaikh, MD,MSc (1) · Guillermo Umpierrez, MD (1) · Kamlesh S Macwan, MD (1) · Kunal Gupta, MD (1) · Laurie Christensen, BS (1) · Manal A Abdel Salam, Professor (1) · Mikkel B Christensen, MD, PhD (1) · Panu Luukkonen, MD, PhD (1) · Richard A Ehrenkranz, MD (1) · Sanjiv Amin, MD (1) · Stanislaw Klek, MD PhD (1) · Stanislaw Klek, PhD (1)
PMID 29960156, PMID 22488002, PMID 28566523, PMID 30307350, PMID 32798567, PMID 39374788
UG1CA189823 (1)