252 completed, 97 unknown, 89 recruiting, 25 not yet recruiting. 522 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 522 | Completed 252, Unknown 97, Recruiting 89, Not yet recruiting 25, Active not recruiting 23, Terminated 14, Withdrawn 14, Enrolling by invitation 7, Suspended 1 |
Follow Heredodegenerative Disorders, Nervous System: new trials by email Literature Review of Heredodegenerative Disorders, Nervous System trials Research Report on Heredodegenerative Disorders, Nervous System
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| IT and IV Lentiviral Gene Therapy for X-ALD Intrathecal and intravenous LV gene therapy - X-linked Adrenoleukodystrophy | Not applicable | Not yet recruiting | Shenzhen Geno-Immune Medical Institute | 30 | 2027-06-01 | 2026-11-02 |
| Assessing the Efficacy of Repeat, Monthly Treatments of Alexandrite Laser for NF1-associated Cutaneous Neurofibromas (cNFs) GentleMax Pro (with skin cooling), GentleMax Pro (without skin cooling) - Neurofibromatosis 1 (NF1), Neurofibromatosis Type I | Not applicable | Suspended | Massachusetts General Hospital | 10 | 2027-01-01 | 2026-06-04 |
| Brain Iron in Beta-Propeller Protein Associated Neurodegeneration (BPAN) Standardized brain MRI including specific sequences usable for Quantitative Susceptibility Mapping (QSM) - Neurodegeneration With Brain Iron Accumulation (NBIA), Iron Metabolism Disorders | Not applicable | Not yet recruiting | University Hospital, Bordeaux | 3 | 2026-12-01 | 2026-10-09 |
| Single Session Support for Parents of Children With Neurodevelopmental Disabilities Struggling With Anxious Avoidance EMPOWER-ND - Neurodevelopmental Disorders, Autism Spectrum Disorder (ASD) | Not applicable | Not yet recruiting | Boston University Charles River Campus | 50 | 2026-11-01 | 2026-10-27 |
| Creatine and Beta-Hydroxy-Beta-Methylbutyrate (HMB) Supplementation Plus Home-Based Exercise for Sarcopenia in Huntington's Disease Creatine monohydrate, Beta-hydroxy-beta-methylbutyrate (HMB), Placebo (microcrystalline cellulose) - Huntington Disease, Sarcopenia | Not applicable | Not yet recruiting | Universidad de Burgos | 88 | 2026-11-01 | 2026-10-28 |
| Evaluating and Promoting Resilience in Adolescents With Tourette Syndrome PRISM Intervention, Usual care intervention - Tourette Syndrome, Tic Disorders | Not applicable | Not yet recruiting | Wake Forest University Health Sciences | 95 | 2026-11-01 | 2026-10-30 |
| Transcutaneous Auricular Vagus Nerve Stimulation for Chronic Tic Disorders/Tourette's Syndrome in Children and Adolescents Transcutaneous auricular vagus nerve stimulation, Sham stimulation - Tourette Syndrome, Chronic Tic Disorder | Not applicable | Not yet recruiting | The First Affiliated Hospital of Zhejiang Chinese Medical University | 124 | 2026-10-31 | 2026-10-28 |
| Cognitive Intervention for Children and Adolescents With NF1 Unstuck and On Target! - Neurofibromatosis 1 (NF1), Executive Function (Cognition) | Not applicable | Not yet recruiting | The Hospital for Sick Children | 60 | 2026-09-28 | 2026-10-13 |
| Impact of a Cardiac Rehabilitation Program on Patients With Cardiac Amyloidosis Cardiac Rehabilitation Program - Amyloidosis | Not applicable | Recruiting | University Hospital, Montpellier | 40 | 2026-09-23 | 2026-10-08 |
| Cryotherapy, PGE2, NGF Levels and Pain After Endodontic Retreatment Intracanal cryotherapy, Room-temperature saline irrigation - Asymptomatic Apical Periodontitis, Endodontic Retreatment | Not applicable | Recruiting | Alanya Alaaddin Keykubat University | 100 | 2026-09-22 | 2026-10-27 |
| Individualized Exercise Training in Cardiac Amyloidosis Exercise Intervention, Physical Activity Handout - Cardiac Amyloidosis | Not applicable | Not yet recruiting | Oregon Health and Science University | 60 | 2026-09-15 | 2026-09-23 |
| Prevalence of Cardiac Thrombi in Cardiac Amyloidosis Cardiac CT scan with contrast - Cardiac Amyloidosis | Not applicable | Recruiting | Centre Hospitalier Universitaire Dijon | 200 | 2026-09-07 | 2026-09-17 |
| Concurrent Training vs Soleus Push-Ups on Neurogenesis-Related Biomarkers in Diabetic Neuropathy Patients Concurrent Training, Soleus Push-ups - Diabetic Peripheral Neuropathy Type 2 | Not applicable | Not yet recruiting | Riphah International University | 99 | 2026-09-01 | 2026-06-30 |
| Detection of Cardiac Amyloidosis Using Right Ventricular Sensing Amplitude in Patients With Left Ventricular Hypertrophy Cardiac amyloidosis screening during CIED implantation - Cardiac Amyloidosis, Left Ventricular Hypertrophy | Not applicable | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 242 | 2026-09-01 | 2026-07-29 |
| Optimizing Parameters of Transcranial Temporal Interference Stimulation for Spinocerebellar Ataxia Type 3 Transcranial Temporal Interference Stimulation (tTIS) - Spinocerebellar Ataxia Type 3 | Not applicable | Not yet recruiting | First Affiliated Hospital of Fujian Medical University | 24 | 2026-08-07 | 2026-09-01 |
| Adapting a Psychosocial Support Intervention for the Rett Syndrome Community Those who have patients prescribed Daybue, Caregiver Speaks + Daybue - Rett Syndrome, Family Caregivers | Not applicable | Not yet recruiting | Colorado State University | 60 | 2026-08-01 | 2026-07-28 |
| Cardiac Output and Fatigue in Friedreich's Ataxia Aerobic Exercise - Friedreich's Ataxia | Not applicable | Recruiting | Scott Barbuto | 30 | 2026-07-15 | 2026-09-22 |
| Integrating Exposure and Response Prevention and Habit Reversal Techniques to Treat a Tourettic Subtype of Obsessive-Compulsive Disorder (Tourettic OCD) Exposure and Response Prevention (ERP), Habit Reversal Training (HbRT, Psychoeducation and Supportive Intervention - Obsessive - Compulsive Disorder, Tic Disorder, Chronic Motor or Vocal | Not applicable | Recruiting | University College London Hospitals | 40 | 2026-07-08 | 2026-07-27 |
| AI-based Echocardiography for Detection of Cardiac Amyloidosis AI-based echocardiogram - Cardiac Amyloidosis, Heart Failure With Preserved Ejection Fraction (HFPEF) | Not applicable | Not yet recruiting | Germans Trias i Pujol Hospital | 200 | 2026-07-01 | 2026-06-12 |
| Early Screening for Cardiac Amyloid Using a History of Bilateral Carpal Tunnel Syndrome Technetium-99m Pyrophosphate (Tc-99m PYP) Scan - Bilateral Carpal Tunnel Syndrome (Diagnosis), Cardiac Amyloidosis | Not applicable | Not yet recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 139 | 2026-07-01 | 2026-05-12 |
Showing 20 of 522. Sign in to see all of them.
Tourette Syndrome (100) · Huntington Disease (63) · Amyloid Neuropathies, Familial (43) · Charcot-Marie-Tooth Disease (42) · Tic Disorders (42) · Spinocerebellar Ataxias (39) · Neurofibromatosis 1 (33) · Myotonic Dystrophy (30) · Tics (30) · Motor Activity (24) · Fragile X Syndrome (21) · Hereditary Sensory and Autonomic Neuropathies (20) · Rett Syndrome (20) · Parkinson Disease (19) · Hepatolenticular Degeneration (17)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (522) · Genetic Diseases, Inborn (519) · Nervous System Diseases (516) · Neurodegenerative Diseases (466) · Central Nervous System Diseases (293) · Brain Diseases (269) · Neuromuscular Diseases (196) · Basal Ganglia Diseases (187) · Movement Disorders (185) · Mental Disorders (183) · Neurologic Manifestations (170) · Peripheral Nervous System Diseases (155) · Pathological Conditions, Signs and Symptoms (148) · Dyskinesias (144)
Exercise (12) · Transcranial Magnetic Stimulation (11) · Transcranial Direct Current Stimulation (9) · Blood Specimen Collection (8) · Deep Brain Stimulation (8) · Magnetic Resonance Imaging (4) · Neuropsychological Tests (4) · Surveys and Questionnaires (4) · Waiting Lists (4) · Activator Appliances (3) · Creatine (3) · Hematologic Tests (3) · Palliative Care (3) · Biofeedback, Psychology (2) · Cognitive Behavioral Therapy (2)
Assistance Publique - Hôpitaux de Paris (19) · Massachusetts General Hospital (16) · Johns Hopkins University (10) · University of Florida (9) · Children's Hospital Medical Center, Cincinnati (8) · University of California, Los Angeles (8) · Institut National de la Santé Et de la Recherche Médicale, France (7) · University Hospital, Angers (7) · IRCCS Eugenio Medea (6) · Institut de Myologie, France (6) · NYU Langone Health (6) · Assistance Publique Hopitaux De Marseille (5) · Chang Gung University (5) · University Hospital, Bordeaux (5) · Columbia University (4)
United States (160) · France (97) · Italy (27) · China (23) · Canada (20) · United Kingdom (17) · Germany (16) · Turkey (Türkiye) (15) · Denmark (14) · Spain (14) · Taiwan (14) · Belgium (10) · Sweden (7) · Switzerland (7) · Austria (6)
Ana-Maria Vranceanu, PhD (4) · Alberto Benussi, MD (3) · Barbara Borroni, MD (3) · Fanny Mochel, MD, PhD (3) · Joseph F McGuire, PhD (3) · Michael Okun, MD (3) · Shannon Bennett, PhD (3) · Vanessa Merker, PhD (3) · Cherie Marvel, PhD (2) · Emily J Ricketts, PhD (2) · Hannah Reese, Ph.D. (2) · Hongxing Wang, MD & PhD (2)
PMID 25803389, PMID 33825853, PMID 37395948, PMID 38908005, PMID 10378380, PMID 10836341, PMID 11202129, PMID 11235929, PMID 11530448, PMID 11886028, PMID 11972163, PMID 12351998, PMID 12541004, PMID 12723873, PMID 12851579, PMID 12874491, PMID 13211501, PMID 1341966, PMID 13679594, PMID 14564276, PMID 14980369, PMID 15107196, PMID 16178020, PMID 16259942, PMID 16387997, PMID 16393016, PMID 16554257, PMID 16970874, PMID 17210425, PMID 17270453, PMID 17517356, PMID 17986401, PMID 18307557, PMID 18347911, PMID 18348596, PMID 1838577, PMID 18616962, PMID 18696285, PMID 18927158, PMID 19141364, PMID 19170198, PMID 19242384, PMID 19276232, PMID 19284553, PMID 19708226, PMID 19833552, PMID 19864199, PMID 19913651, PMID 20103757, PMID 20194584
2017 (2), 2025 (2), K23HD109375 (2), UL1TR002345 (2), 2018 (1), 2019 (1), 2023 (1), K23MH113884 (1), K23MH141319 (1), K23NR020210 (1), KL2TR003016 (1), P50MH077248 (1), R01AG076678 (1), R01AG078169 (1), R01AT012455 (1)