8 completed, 3 unknown, 2 active not recruiting, 1 not yet recruiting. 15 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 15 | Completed 8, Unknown 3, Active not recruiting 2, Not yet recruiting 1, Terminated 1 |
Follow Activator Appliances: new trials by email Literature Review of Activator Appliances trials Research Report on Activator Appliances
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Activator Trigger Point and Shock Wave Therapy on Pain and Function in Active Upper Trapezius Trigger Points: A Randomized Controlled Study Shockwave, Activator - Cervical | Not applicable | Not yet recruiting | Cairo University | 100 | 2026-07-01 | 2026-05-18 |
| The Effect of Mandibular Advancement With Clear Aligners on Maxillary and Mandibular Volumes Mandibular Advancement Appliance (Invisalign MA), Activator Appliance - Mandibular Retrognathia | Not applicable | Completed | Batman University | 55 | 2025-05-01 | 2025-07-09 |
| Investigating the Impact of JASPER Behavioral Therapy in Children With Down Syndrome JASPER, Psychoeducational Curriculum - Down Syndrome | Not applicable | Completed | Boston Children's Hospital | 103 | 2023-01-23 | 2026-04-13 |
| Mandibular Advancement Clear Aligner Treatment in Juvenile Idiopathic Arthritis Subjects Device: orthodontic - mandibular advancement clear aligner - Juvenile Idiopathic Arthritis, Malocclusion, Angle Class II | Not applicable | Unknown | University of Genova | 50 | 2022-10-01 | 2022-07-20 |
| Boosting Language Outcomes of Minimally Verbal Children With ASD (BLOOM) JASPER, PROMPT - Autism Spectrum Disorder | Not applicable | Active not recruiting | University of California, Los Angeles | 56 | 2021-04-29 | 2026-07-23 |
| PRISM Intervention Study JASPER, DTT (Discrete Trial Training) - Autism Spectrum Disorder | Not applicable | Active not recruiting | University of California, Los Angeles | 140 | 2021-03-01 | 2026-07-16 |
| Community-based Adaptive Autism Intervention for Toddlers JASPER, JASPER Plus+ - Autism Spectrum Disorder | Not applicable | Completed | University of California, Los Angeles | 201 | 2020-12-03 | 2026-10-09 |
| TSC Remote Assessment and Intervention JASPER - TSC | Not applicable | Completed | University of California, Los Angeles | 54 | 2020-10-31 | 2024-10-30 |
| JASPER Intervention in Down Syndrome JASPER - Down Syndrome, Trisomy 21 | Not applicable | Completed | Boston Children's Hospital | 12 | 2018-12-01 | 2022-01-18 |
| The Effect of Functional Treatment of Patients With Backward Positioned Chins on the Jaw Joint and Movements Activator, Twin Block - Malocclusion, Angle Class II, Retrognathism | Not applicable | Completed | Damascus University | 66 | 2018-06-15 | 2020-02-05 |
| JASPER Early Intervention for Tuberous Sclerosis JASPER - Tuberous Sclerosis | Not applicable | Unknown | University of California, Los Angeles | 64 | 2017-10-24 | 2020-11-06 |
| Early Treatment of Skeletal Anterior Open Bite by Two Appliances Bionator, Removable Appliance with Posterior Bite Planes - Open Bite | Not applicable | Completed | Damascus University | 40 | 2017-08-15 | 2020-04-08 |
| Training Early Social Language in Autism Jasper, Parent Education - Autism Spectrum Disorder | Not applicable | Terminated | Boston University Charles River Campus | 89 | 2016-07-01 | 2026-07-17 |
| Early Behavioral Intervention to Improve Social Communication Function in Infants With Tuberous Sclerosis Complex JASPER - Tuberous Sclerosis Complex | Not applicable | Completed | University of California, Los Angeles | 8 | 2015-09-01 | 2026-07-23 |
| the Hypoalgesic Effect of Spinal Manual Therapy spinal manual therapy - Back Pain | Not applicable | Unknown | Institut Franco Europeen de Chiropratique | 90 | 2013-11-01 | 2013-10-08 |
Autism Spectrum Disorder (4) · Autistic Disorder (4) · Tuberous Sclerosis (3) · Communication (2) · Down Syndrome (2) · Emotional Regulation (2) · Malocclusion, Angle Class II (2) · Arthritis, Juvenile (1) · Back Pain (1) · Child Development Disorders, Pervasive (1) · Epilepsy (1) · Micrognathism (1) · Open Bite (1) · Retrognathia (1) · Speech (1)
University of California, Los Angeles (6) · Boston Children's Hospital (2) · Damascus University (2) · Batman University (1) · Boston University Charles River Campus (1) · Cairo University (1) · Institut Franco Europeen de Chiropratique (1) · University of Genova (1)
United States (9) · Syria (2) · Australia (1) · Egypt (1) · Italy (1) · Turkey (Türkiye) (1)
Abdulmalek Majanni, DDS MSc (1) · Hassan Farah, DDS MSc PhD (1) · Helen Tager-Flusberg, PhD (1) · Issam Khoury, DDS MSc PhD (1) · Mahran Raheel Mousa, DDS MSc (1) · Mohammad Y Hajeer, DDS MSc PhD (1) · Nicole Baumer, MD, MEd (1) · Shafali Jeste (1) · Shafali Jeste, MD (1)
PMID 31969108, PMID 34462242, PMID 38862831, PMID 41709259
R01HD090138 (1)