10 completed, 10 recruiting, 4 unknown, 3 active not recruiting. 29 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 29 | Completed 10, Recruiting 10, Unknown 4, Active not recruiting 3, Not yet recruiting 2 |
Follow Heart Failure NYHA Class III: new trials by email Literature Review of Heart Failure NYHA Class III trials Research Report on Heart Failure NYHA Class III
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart Failure Barostim System, Usual care medical management - Heart Failure, Heart Failure NYHA Class II | Not applicable | Recruiting | CVRx, Inc. | 2500 | 2026-04-24 | 2026-10-21 |
| Heart Failure Management for Patient With CIED Remotely Monitored SmartSignalHF, HF RM standard of care - Heart Failure, Heart Failure NYHA Class II | Not applicable | Recruiting | Implicity | 1132 | 2025-12-19 | 2026-03-31 |
| REDUCED FUNCTIONALITY AND KINESIOPHOBIA IN PATIENTS WITH HEART FAILURE: USE OF ALTERNATIVE THERAPEUTIC STRATEGIES Low Frequency Neuromuscular Electrical Stimulation, Medium Frequency Neuromuscular Electrical Stimulation, Neuromuscular Electrical Stimulation without generating contractility - Heart Failure, Heart Failure NYHA Class III | Not applicable | Not yet recruiting | Universidade Federal do Rio Grande do Norte | 54 | 2025-08-18 | 2025-08-01 |
| Optimization of STAR STAR condition 1, STAR condition 2, STAR condition 3 - Heart Failure NYHA Class II, Heart Failure NYHA Class III | Not applicable | Not yet recruiting | UMC Utrecht | 320 | 2025-07-01 | 2025-07-15 |
| An Early Feasibility Study Evaluation of an Implant Free Interatrial Shunt to Improve Heart Failure PAS-C System - Heart Failure, Heart Failure NYHA Class III | Not applicable | Active not recruiting | InterShunt Technologies, Inc. | 20 | 2025-05-15 | 2026-05-27 |
| Sustaining Home Heart Failure Palliative Care in Rural Appalachia HF-FamPALhomeCARE - Heart Failure NYHA Class III, Heart Failure NYHA Class IV | Not applicable | Recruiting | West Virginia University | 208 | 2025-04-01 | 2026-03-09 |
| Atrial Appendage Micrograft Transplants to Assist Heart Repair After Cardiac Surgery Epicardial AAMs-patch transplantation, RNA-stabilized whole blood sampling, Plasma sampling - Ischemic Heart Disease, Ischemic Cardiomyopathy | Not applicable | Recruiting | Hospital District of Helsinki and Uusimaa | 50 | 2024-04-01 | 2024-04-19 |
| Comprehensive Hybrid Cardiac Rehabilitation Trial on Heart Failure Comprehensive Initial Assessment, Continuous evaluation, Interval Exercise - Heart Failure NYHA Class II, Heart Failure NYHA Class III | Not applicable | Recruiting | Universidad de La Frontera | 152 | 2024-04-01 | 2024-12-03 |
| PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III Cordella™ Pulmonary Artery Sensor System - Heart Failure NYHA Class II, Heart Failure NYHA Class III | Not applicable | Recruiting | Endotronix, Inc. | 1750 | 2023-11-29 | 2026-06-29 |
| A Study to Improve Physician-Youth Communication and Medical Decision Making We Chatt communication tool, Usual/standard care - Heart Failure NYHA Class II, Heart Failure NYHA Class III | Not applicable | Completed | University of Michigan | 62 | 2023-09-14 | 2025-06-18 |
| Yoga Based Cardiac Rehabilitation in Heart Failure Failure Yoga-CaRe HF, Health Education - Heart Failure With Reduced Ejection Fraction, Heart Failure NYHA Class II | Not applicable | Recruiting | Centre for Chronic Disease Control, India | 3500 | 2023-04-24 | 2026-09-14 |
| Assessment of the Effectiveness, Socio-economic Impact and Implementation of a Digital Solution for Severe Patients ADLIFE intervention - Heart Failure NYHA Class III, Heart Failure NYHA Class IV | Not applicable | Completed | Biosistemak Institute for Health Systems Research | 185 | 2023-02-01 | 2025-03-10 |
| Implementation and Cost-evaluation of a Smartphone-based Telemonitoring and Digital Support in Patients With HF Comunicare Solutions Smartphone Application, Completing a quality of life (QOL)-questionnaire - Heart Failure, Heart Failure NYHA Class II | Not applicable | Unknown | Comunicare Solutions SA | 330 | 2022-05-21 | 2022-08-04 |
| Promoting Well-being and Health in Heart Failure PP-MI Intervention, MI-alone Intervention - Heart Failure, Heart Failure NYHA Class I | Not applicable | Recruiting | Massachusetts General Hospital | 280 | 2021-11-29 | 2026-04-14 |
| Algorithm Using LINQ Sensors for Evaluation And Treatment of Heart Failure Reveal LINQ™ Insertable Cardiac Monitor with investigational ALLEVIATE-HF RAMware download, Medication intervention, Not Randomized to Device or Medication Intervention - Heart Failure NYHA Class II, Heart Failure NYHA Class III | Not applicable | Completed | Medtronic Cardiac Rhythm and Heart Failure | 826 | 2020-09-03 | 2026-08-26 |
| Mid-Q Response Study aCRT ON, aCRT OFF - Heart Failure, Left Bundle-Branch Block | Not applicable | Completed | Medtronic Cardiac Rhythm and Heart Failure | 177 | 2020-01-23 | 2025-07-09 |
| Family Palliative and End-of-Life Care for Advanced Heart Failure FamPALcare - Heart Failure NYHA Class III, Heart Failure NYHA Class IV | Not applicable | Completed | West Virginia University | 78 | 2020-01-13 | 2025-02-19 |
| PROACTIVE-HF IDE Trial Heart Failure NYHA Class III Cordella™ Pulmonary Artery Sensor System - Heart Failure NYHA Class III | Not applicable | Active not recruiting | Endotronix, Inc. | 738 | 2020-01-10 | 2026-07-24 |
| SIRONA 2 Trial Heart Failure NYHA Class III Cordella™ Pulmonary Artery Sensor System - Heart Failure NYHA Class III | Not applicable | Active not recruiting | Endotronix, Inc. | 81 | 2019-06-26 | 2026-07-27 |
| Effect of DASH Eating Pattern on Heart Failure Outcomes DASH Eating Pattern - Heart Failure NYHA Class III | Not applicable | Unknown | University of Georgia | 36 | 2018-11-15 | 2018-11-16 |
Showing 20 of 29. Sign in to see all of them.
Heart Failure (23) · Cardiovascular Diseases (4) · Heart Diseases (4) · Motor Activity (4) · Heart Failure, Systolic (2) · Bundle-Branch Block (1) · Coronary Artery Disease (1) · Dyspnea (1) · Heart Failure, Diastolic (1) · Kinesiophobia (1) · Lymphoma, Follicular (1) · Medication Adherence (1) · Myocardial Ischemia (1) · Tricuspid Valve Insufficiency (1)
Cardiovascular Diseases (20) · Heart Diseases (20) · Behavior (4) · Pathological Conditions, Signs and Symptoms (2) · Anxiety Disorders (1) · Arrhythmias, Cardiac (1) · Arterial Occlusive Diseases (1) · Arteriosclerosis (1) · Cardiac Conduction System Disease (1) · Coronary Disease (1) · Health Behavior (1) · Heart Block (1) · Heart Failure (1) · Heart Valve Diseases (1) · Hemic and Lymphatic Diseases (1)
Activities of Daily Living (1) · Blood Specimen Collection (1) · Echocardiography (1) · Echocardiography, Transesophageal (1) · Exercise (1) · Psychiatric Rehabilitation (1) · Resistance Training (1) · Standard of Care (1) · Telerehabilitation (1) · Walking (1)
Endotronix, Inc. (4) · Medtronic Cardiac Rhythm and Heart Failure (2) · West Virginia University (2) · Aalborg University (1) · Abbott Medical Devices (1) · Biosistemak Institute for Health Systems Research (1) · CVRx, Inc. (1) · Centre for Chronic Disease Control, India (1) · Comunicare Solutions SA (1) · Guangdong Provincial Hospital of Traditional Chinese Medicine (1) · Hospital District of Helsinki and Uusimaa (1) · Implicity (1) · Indiana University (1) · InterShunt Technologies, Inc. (1) · Massachusetts General Hospital (1)
United States (15) · Belgium (5) · Ireland (4) · Denmark (3) · China (2) · Germany (2) · Brazil (1) · Brunei (1) · Canada (1) · Chile (1) · Finland (1) · France (1) · Hong Kong (1) · India (1) · Indonesia (1)
Edward Karst (3) · Andrea Sauerland (1) · Birthe Dinesen, PhD (1) · Christopher M Celano, MD (1) · Dorairaj Prabhakaran, MD DM (Cardiology) (1) · Elisabeth L Sattler, PhD, BSPharm (1) · Esteban de Manuel (1) · Gaetano Marrone (1) · Heleen Westland, PhD (1) · Javed Butler, MD (1) · Jens Refsgaard, MD, PhD (1) · Kazutaka Aonuma, MD (1) · Kei Togashi, MD, MPH (1) · Malene Hollingdal, MD, PhD (1)
PMID 29490680, PMID 31538944, PMID 32264715, PMID 34255642, PMID 34386535, PMID 34461042, PMID 34763080, PMID 35266003, PMID 35928510, PMID 36456066, PMID 36894879, PMID 36920122, PMID 37286262, PMID 37943225, PMID 39097733, PMID 39152983, PMID 39392161, PMID 39480670, PMID 39610971, PMID 40055735, PMID 40223608, PMID 41485016, PMID 41686133, PMID 42168470, PMID 42201276, PMID 42201288, PMID 42206402
K23HL145096 (1), R01NR021630 (1), R15NR018547 (1)