8 completed, 5 unknown, 3 recruiting, 2 terminated. 8 Not applicable, 4 Phase 1, 2 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 3, Recruiting 2, Unknown 2, Terminated 1 |
| Phase 1 | 4 | Completed 3, Terminated 1 |
| Phase 2 | 2 | Completed 1, Unknown 1 |
| Phase 3 | 1 | Withdrawn 1 |
Follow Gastrointestinal Motility Disorder: new trials by email Literature Review of Gastrointestinal Motility Disorder trials Research Report on Gastrointestinal Motility Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Association Between Preoperative Mediterranean Diet Adherence and Postoperative Bowel Motility Post Abdominal Surgery, Gastrointestinal Motility Disorder | Completed | Bahçeşehir University | 110 | 2026-01-23 | 2026-09-08 | |
| Coffee Consumption After Laparoscopic Hysterectomy Postoperative Coffee Consumption - Hysterectomy, Gastrointestinal Motility Disorder | Not applicable | Completed | Istanbul Medipol University Hospital | 50 | 2025-05-12 | 2026-07-07 |
| "The Effect of Abdominal Massage on Gastrointestinal Functions in Mechanically Ventilated Patients Receiving Enteral Nutrition in Intensive Care" Abdominal Massage - Defecation Disorder, Gastrointestinal Motility Disorder | Not applicable | Recruiting | Mersin University | 70 | 2025-01-06 | 2025-02-19 |
| Interrogating the Pathophysiological Mechanisms of Constipation in Patients With Systemic Sclerosis Transcutaneous Electrical Acustimulation (TEA), Sham-TEA - Systemic Sclerosis, Constipation | Not applicable | Recruiting | The University of Texas Health Science Center, Houston | 60 | 2024-02-17 | 2025-06-26 |
| Short-term Effect of Exercise and Self-manual Approaches to Bloating - Distention Group 1 (exercise and self-manual approaches targeting only the diaphragm muscles), Group 2 (exercise and self-manual approaches targeting both diaphragm and core muscles) - Gastrointestinal System Disease, Functional Bloating | Not applicable | Unknown | Ege University | 24 | 2023-01-01 | 2024-05-29 |
| The Effect of Foot Reflexology After Cesarean Section Postoperative Pain, Gastrointestinal Motility Disorder | Unknown | Nülüfer Erbil | 70 | 2022-05-01 | 2022-03-07 | |
| Rifaximin's Effect on Covert Hepatic Encephalopathy With SIBO and Gastrointestinal Dysmotility Rifaximin - Cirrhosis, Liver, Minimal Hepatic Encephalopathy | Phase 3 | Withdrawn | MetroHealth Medical Center | 2021-09-15 | 2025-12-24 | |
| Gastrointestinal Motor Disorders (Esophageal and Anorectal) After COVID-19 Gastrointestinal Motility Disorder | Unknown | University Hospital Dubrava | 120 | 2021-08-15 | 2021-09-30 | |
| IVIG for Drug and Device Refractory Gastrointestinal Auto-Immune Neuropathy Gastrointestinal Motility Disorder, Gastroparesis | Recruiting | University of Louisville | 400 | 2020-01-02 | 2025-08-01 | |
| Intestinal Dysmotility in Patients With Functional Digestive Symptoms High resolution intestinal manometry - Gastrointestinal Motility Disorder | Not applicable | Unknown | Hospital Universitari Vall d'Hebron Research Institute | 50 | 2018-11-07 | 2021-11-22 |
| Lanreotide in the Treatment of Small Bowel Motility Disorders Lanreotide - Gastrointestinal Motility Disorder, Intestinal Disease | Phase 2 | Completed | Northwell Health | 12 | 2017-05-11 | 2021-01-15 |
| Oropharyngeal Administration of Mother's Milk in Preterm Infants and Gastrointestinal Motility Oro-pharyngeal Administration of Mother's Milk - Preterm Infant, Feeding Disorder Neonatal | Not applicable | Completed | Mansoura University Children Hospital | 20 | 2016-06-01 | 2021-03-15 |
| Gastrointestinal Motility Among Diabetes Patients 11C Donepezil PET/CT scan, 3D-Transit, 3D-Transit during treatment with Pyridostigmine - Diabetic Autonomic Neuropathy, Gastrointestinal Motility Disorder | Not applicable | Terminated | University of Aarhus | 40 | 2015-10-01 | 2021-01-08 |
| The Effect of Prucalopride (Resolor®) on Gastric Motor Function and Gastric Sensitivity Prucalopride, Placebo - Gastrointestinal Motility Disorder, Dyspepsia | Not applicable | Completed | Universitaire Ziekenhuizen KU Leuven | 17 | 2013-09-26 | 2021-10-26 |
| Nitric Oxide Control of Migrating Motor Complex: L-NMMA Effects in Relation to Receptor Blockades L-Nitro-Monomethyl-Arginine (LNMMA) 10 mg/kg IV, saline - Gastrointestinal Motility Disorder, Disturbance of Salivary Secretion | Phase 1 | Completed | Uppsala University | 29 | 2013-06-01 | 2014-09-19 |
| A Phase 1, Multiple Intravenous Dose Study to Examine Safety, Tolerability, and PK of Intravenous TD-8954, a 5-HT4 Receptor Agonist, in Healthy Subjects TD-8954, Placebo - saline - Gastrointestinal Motility Disorder | Phase 1 | Terminated | Theravance Biopharma | 16 | 2012-09-01 | 2017-08-02 |
| Study to Assess Pharmacodynamics of RM-131 in Patients With Diabetic Gastroparesis RM-131, Placebo - Diabetes Mellitus Type 1 and 2, Diabetes Mellitus Complications | Phase 1 | Completed | Motus Therapeutics, Inc. | 20 | 2011-07-01 | 2016-09-22 |
| Absorption of Paracetamol, Talinolol and Amoxicillin After Oral Administration Using Non-caloric and Caloric Water Acetaminophen, Talinolol, Amoxicillin - Gastrointestinal Motility Disorder | Phase 1 | Completed | University Medicine Greifswald | 12 | 2011-04-01 | 2012-07-09 |
| Can SMOFlipid®, A Composite Parenteral Nutrition Lipid Emulsion, Prevent Progression Of Parenteral Nutrition Associated Liver Disease In Infants? Intralipid 20%, SMOFlipid 20% - Short Bowel Syndrome, Intestinal Failure | Phase 2 | Unknown | The Hospital for Sick Children | 24 | 2009-01-01 | 2011-11-03 |
Gastroparesis (2) · Abdominal Pain (1) · Constipation (1) · Diabetes Complications (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 1 (1) · Diabetic Neuropathies (1) · Digestive System Diseases (1) · Dilatation, Pathologic (1) · Dyspepsia (1) · Hyperphagia (1) · Intestinal Diseases (1) · Intestinal Failure (1) · Liver Cirrhosis (1) · Liver Failure (1)
Pathological Conditions, Signs and Symptoms (8) · Signs and Symptoms (6) · Digestive System Diseases (5) · Gastrointestinal Diseases (4) · Signs and Symptoms, Digestive (4) · Neurologic Manifestations (3) · Pathologic Processes (3) · Endocrine System Diseases (2) · Glucose Metabolism Disorders (2) · Liver Diseases (2) · Metabolic Diseases (2) · Nervous System Diseases (2) · Nutritional and Metabolic Diseases (2) · Pain (2) · Paralysis (2)
4-((4-((2-isopropyl-1H-benzoimidazole-4-carbonyl)amino)methyl)piperidin-1-ylmethyl)piperidine-1-carboxylic acid methyl ester (1) · Acetaminophen (1) · Amoxicillin (1) · Cyclin-Dependent Kinase Inhibitor p15 (1) · Exercise (1) · Pyridostigmine Bromide (1) · Rifaximin (1) · Sodium Chloride (1) · lanreotide (1) · omega-N-Methylarginine (1) · prucalopride (1) · relamorelin (1) · talinolol (1)
Bahçeşehir University (1) · Ege University (1) · Hospital Universitari Vall d'Hebron Research Institute (1) · Istanbul Medipol University Hospital (1) · Mansoura University Children Hospital (1) · Mersin University (1) · MetroHealth Medical Center (1) · Motus Therapeutics, Inc. (1) · Northwell Health (1) · Nülüfer Erbil (1) · The Hospital for Sick Children (1) · The University of Texas Health Science Center, Houston (1) · Theravance Biopharma (1) · Universitaire Ziekenhuizen KU Leuven (1) · University Hospital Dubrava (1)
United States (5) · Turkey (Türkiye) (4) · Canada (1) · Croatia (1) · Denmark (1) · Egypt (1) · Germany (1) · Spain (1) · Sweden (1)
Brett Haumann, SVP, Clinical Development (1) · Jan Tack, MD (1) · Klaus Krogh, Professor (1) · Larry Miller, M.D. (1) · Michael Camilleri, MD (1) · Paul Wales (1) · Per M Hellstrom, MD, prof (1) · Ronnie Fass, MD (1) · Zsuzsanna H McMahan, MD, MHS (M-PI) (1)
PMID 19302262, PMID 20675008, PMID 20849805, PMID 21157444, PMID 22961573, PMID 23639598, PMID 25932262, PMID 26644276, PMID 26838529, PMID 29776873, PMID 30231787, PMID 33615630, PMID 39223844, PMID 41353487
R01AR081382 (1)