48 completed, 7 unknown, 3 not yet recruiting, 3 recruiting. 22 Phase 3, 14 Phase 2, 12 Phase 1, 11 Phase 4, 8 Not applicable.
Follow prucalopride: new trials by email Literature Review of prucalopride trials Research Report on prucalopride
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prucalopride for Cognitive Functioning in Schizophrenia Prucalopride 1 MG - Schizophrenia | Not applicable | Not yet recruiting | University of Pittsburgh | 34 | 2027-05-31 | 2026-09-17 |
| PROMOTE: Effects of 5-HT4 Agonism on Cognition and Sleep in Peopl With Low Mood Prucalopride, Placebo Comparator - Low Mood, Depression - Major Depressive Disorder | Not applicable | Not yet recruiting | University of Oxford | 60 | 2026-10-01 | 2026-10-06 |
| Prucaloprida vs Bisacodyl as a Stimulant in Bowel Preparation for Video Colonoscopy in Adults Bisacodyl 5 MG, Prucalopride 2mg - Bowel Preparation | Early Phase 1 | Not yet recruiting | Hospital de Clínicas Dr. Manuel Quintela | 124 | 2025-09-01 | 2025-08-17 |
| Impact of Varying Doses of Prucalopride on Improving Gut Function Recovery After Elective Colorectal Surgery Prucalopride 2mg, Prucalopride 4mg, Standard Care - Post-Op Complication | Phase 3 | Recruiting | Future University in Egypt | 180 | 2025-03-02 | 2025-03-19 |
| Gastrointestinal Dysmotility on Aspiration Risk Prucalopride, Famotidine - Esophageal Motility Disorders, Gastric Motor Dysfunction | Phase 4 | Recruiting | Boston Children's Hospital | 120 | 2025-02-13 | 2026-08-03 |
| Evolution of the Chicago Classification: Bridging Physiology and Mechanics FLIP, HRM, Prucalopride - Dysphagia, Achalasia, Esophageal | Not applicable | Recruiting | Northwestern University | 575 | 2024-09-01 | 2026-09-23 |
| Bowel Preparation Regimen for Colon Capsule Endoscopy Procedure polyethylene glycol, sodium phosphate, polyethylene glycol + ascorbic acid - Colon Cancer, Inflammatory Bowel Diseases | Phase 3 | Completed | Region Skane | 147 | 2023-02-01 | 2024-02-28 |
| The Effect of Prucalopride on Gastric Emptying in Intensive Care Unit Patients Prucalopride, Metoclopramide - Enteral Feeding Intolerance | Phase 1 / Phase 2 | Completed | Ain Shams University | 70 | 2022-08-30 | 2024-04-12 |
| Preventing Gastric Glitch With Prucalopride and Buspirone: N-of-1 Clinical Trial Prucalopride, Buspirone, Placebo - Dyspepsia | Phase 1 / Phase 2 | Completed | Universidade de Passo Fundo | 1 | 2022-01-06 | 2022-05-17 |
| Prucalopride and Cognition in Recovered Depression Prucalopride, Placebo - Depression in Remission | Not applicable | Completed | University of Oxford | 50 | 2022-01-04 | 2024-02-09 |
| Prucalopride for Postoperative Ileus in Patients Undergoing Robot-assisted Laparoscopic Radical Cystectomy Prucalopride, Placebo - Postoperative Ileus, Bladder Cancer | Phase 2 | Unknown | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 160 | 2021-09-01 | 2021-08-12 |
| Study of Comparative Effectiveness of Prucalopride and Lubiprostone in Constipation Predominant Irritable Bowel Syndrome Prucalopride 2mg - Patient Satisfaction | Phase 4 | Unknown | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 140 | 2021-08-15 | 2021-08-30 |
| A Study of Prucalopride For Functional Constipation in Children and Teenagers Prucalopride, Placebo - Constipation | Phase 3 | Terminated | Takeda | 175 | 2021-07-13 | 2024-06-06 |
| The Effects of Prucalopride in Patients With Constipation Predominant Irritable Bowel Syndrome Prucalopride 2mg - Irritable Bowel Syndrome | Phase 2 / Phase 3 | Unknown | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 160 | 2021-03-10 | 2021-10-22 |
| Prucalopride Treatment for Refractory Gastro-esophageal Reflux Disease Prucalopride, Placebo Oral Tablet - GERD | Phase 4 | Unknown | Universitaire Ziekenhuizen KU Leuven | 60 | 2019-02-18 | 2019-12-05 |
| Effects of Seven Day Prucalopride Administration in Healthy Volunteers Prucalopride, Placebo - Molecular Mechanisms of Pharmacological Action, Depression | Not applicable | Completed | University of Oxford | 50 | 2018-06-11 | 2022-11-18 |
| Prucalopride in Postoperative Ileus Prucalopride, Placebo Oral Capsule - Postoperative Ileus, Colorectal Surgery | Phase 3 | Completed | University of Auckland, New Zealand | 150 | 2017-10-25 | 2021-09-29 |
| Treatment of Dysphagia and Ineffective Esophageal Motility With Prucalopride: A Pilot Study Prucalopride - Ineffective Esophageal Motility, Dysphagia | Phase 2 | Completed | University of Calgary | 28 | 2017-10-20 | 2020-03-25 |
| Efficacy of PRUcalopride in Critically Ill Patients With Paralytic ILeus Prucalopride, Placebo - Paralytic Ileus, Critically Ill | Phase 3 | Unknown | Prince of Songkla University | 62 | 2017-07-01 | 2020-02-06 |
| Effects of Acute Prucalopride Administration in Healthy Volunteers Prucalopride, Placebo - Molecular Mechanisms of Pharmacological Action, Depression | Not applicable | Completed | University of Oxford | 41 | 2017-02-07 | 2019-03-05 |
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Constipation (27) · Depression (3) · Deglutition Disorders (2) · Depressive Disorder (2) · Dyspepsia (2) · Gastroesophageal Reflux (2) · Gastrointestinal Hemorrhage (2) · Gastroparesis (2) · Inflammatory Bowel Diseases (2) · Mental Disorders (2) · Mood Disorders (2) · Postoperative Complications (2) · Celiac Disease (1) · Cognition Disorders (1) · Colonic Neoplasms (1)
Movetis (22) · Shire (5) · Universitaire Ziekenhuizen KU Leuven (4) · University of Oxford (4) · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh (2) · Queen's University (2) · University of Calgary (2) · Yuhan Corporation (2) · Ain Shams University (1) · Boston Children's Hospital (1) · Future University in Egypt (1) · Guang'anmen Hospital of China Academy of Chinese Medical Sciences (1) · Hospital de Clínicas Dr. Manuel Quintela (1) · Janssen Korea, Ltd., Korea (1) · Janssen Pharmaceutica (1)
Belgium (10) · United Kingdom (6) · Canada (5) · United States (5) · China (4) · South Korea (4) · Romania (3) · Bangladesh (2) · Czechia (2) · Egypt (2) · Germany (2) · Netherlands (2) · Poland (2) · Sweden (2) · Thailand (2)
Susannah E Murphy, DPhil (3) · Harald Winter, M.D. (2) · Lawrence Hookey (2) · Marc Van Outryve, MD (2) · Angharad de Cates, MRCPsych (1) · Christopher N Andrews, MD, MSc (1) · D O'Neill, MD (1) · Darlene Brady (1) · Eman Elmokadem, PhD (1) · Ervin Toth, MD PhD (1) · Fergal Donnellan, MD (1) · Fernando Fornari (1) · Georges Coremans, MD (1)
PMID 34585675, PMID 39664231, PMID 24106924, PMID 24732867, PMID 24917940, PMID 25581251, PMID 21039673, PMID 23535761, PMID 12144586, PMID 12743445, PMID 18509121, PMID 18987031, PMID 19751247, PMID 20529205, PMID 21848574, PMID 23269861, PMID 23480216, PMID 23539257, PMID 25239590, PMID 25808103, PMID 25869393, PMID 26880227, PMID 27270968, PMID 27891230, PMID 30472681, PMID 33273258, PMID 33615630, PMID 35639621, PMID 37098409, PMID 37215389, PMID 39584139, PMID 41080507
2009 (2), D43TW009114 (1)