3 completed, 1 terminated. 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 3, Terminated 1 |
Follow Gastrointestinal Motility Disorder: new trials by email Literature Review of Gastrointestinal Motility Disorder trials Research Report on Gastrointestinal Motility Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nitric Oxide Control of Migrating Motor Complex: L-NMMA Effects in Relation to Receptor Blockades L-Nitro-Monomethyl-Arginine (LNMMA) 10 mg/kg IV, saline - Gastrointestinal Motility Disorder, Disturbance of Salivary Secretion | Phase 1 | Completed | Uppsala University | 29 | 2013-06-01 | 2014-09-19 |
| A Phase 1, Multiple Intravenous Dose Study to Examine Safety, Tolerability, and PK of Intravenous TD-8954, a 5-HT4 Receptor Agonist, in Healthy Subjects TD-8954, Placebo - saline - Gastrointestinal Motility Disorder | Phase 1 | Terminated | Theravance Biopharma | 16 | 2012-09-01 | 2017-08-02 |
| Study to Assess Pharmacodynamics of RM-131 in Patients With Diabetic Gastroparesis RM-131, Placebo - Diabetes Mellitus Type 1 and 2, Diabetes Mellitus Complications | Phase 1 | Completed | Motus Therapeutics, Inc. | 20 | 2011-07-01 | 2016-09-22 |
| Absorption of Paracetamol, Talinolol and Amoxicillin After Oral Administration Using Non-caloric and Caloric Water Acetaminophen, Talinolol, Amoxicillin - Gastrointestinal Motility Disorder | Phase 1 | Completed | University Medicine Greifswald | 12 | 2011-04-01 | 2012-07-09 |
Diabetes Complications (1) · Diabetes Mellitus, Type 1 (1) · Gastroparesis (1)
Autoimmune Diseases (1) · Diabetes Mellitus (1) · Digestive System Diseases (1) · Endocrine System Diseases (1) · Gastrointestinal Diseases (1) · Glucose Metabolism Disorders (1) · Immune System Diseases (1) · Metabolic Diseases (1) · Neurologic Manifestations (1) · Nutritional and Metabolic Diseases (1) · Paralysis (1) · Pathological Conditions, Signs and Symptoms (1) · Signs and Symptoms (1) · Stomach Diseases (1)
4-((4-((2-isopropyl-1H-benzoimidazole-4-carbonyl)amino)methyl)piperidin-1-ylmethyl)piperidine-1-carboxylic acid methyl ester (1) · Acetaminophen (1) · Amoxicillin (1) · Sodium Chloride (1) · omega-N-Methylarginine (1) · relamorelin (1) · talinolol (1)
Motus Therapeutics, Inc. (1) · Theravance Biopharma (1) · University Medicine Greifswald (1) · Uppsala University (1)
United States (2) · Germany (1) · Sweden (1)
Brett Haumann, SVP, Clinical Development (1) · Michael Camilleri, MD (1) · Per M Hellstrom, MD, prof (1)