101 terminated. 101 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 101 | Terminated 101 |
Follow Gastrointestinal Diseases: new trials by email Literature Review of Gastrointestinal Diseases trials Research Report on Gastrointestinal Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ketamine-assisted Therapy for Advanced GI Cancer Ketamine, Ketamine Injectable Product, Meaning and Purpose therapy - Pancreatic Ductal Adenocarcinoma, Pain, Acute | Phase 4 | Terminated | Brian Anderson, MD | 1 | 2024-05-17 | 2025-05-21 |
| Sugammadex vs Neostigmine Reversal in Pediatric Appendectomy Sugammadex, Neostigmine/Glycopyrrolate - Appendicitis, Surgery | Phase 4 | Terminated | Emory University | 22 | 2023-07-19 | 2025-09-30 |
| Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure - UCSF Multiple standard of care antibiotics for appendicitis, at physicians' discretion - Appendicitis | Phase 4 | Terminated | University of California, San Francisco | 42 | 2023-06-06 | 2026-10-27 |
| An Open-label Study of Ozanimod in Moderate to Severe Ulcerative Colitis in Clinical Practice Ozanimod - Colitis, Ulcerative | Phase 4 | Terminated | Bristol-Myers Squibb | 139 | 2022-12-16 | 2026-02-10 |
| Pilot Study of Posaconazole in Crohn's Disease Posaconazole Delayed Release Oral Tablet, Matching Placebo Tablet - Crohn Disease, CARD9 S12N Risk Allele | Phase 4 | Terminated | Cedars-Sinai Medical Center | 10 | 2022-08-17 | 2026-02-24 |
| Effect of Intravenous Iron Supplementation on Celiac Disease Remission (IRONCEL) Ferinject, oral iron - Celiac Disease | Phase 4 | Terminated | Assistance Publique - Hôpitaux de Paris | 1 | 2022-07-08 | 2026-07-09 |
| Sodium Citrate 4% Locking Solution for Children Requiring Home Parenteral Nutrition Sodium Citrate 4% Inj Syringe 3Ml - CLABSI - Central Line Associated Bloodstream Infection | Phase 4 | Terminated | Johns Hopkins University | 1 | 2022-03-28 | 2024-09-19 |
| The Effect of Chemoradiotherapy on Gastric Perfusion in Patients With Gastric Cancer. Indocyanine green - Gastric Cancer | Phase 4 | Terminated | Copenhagen University Hospital, Rigshospitalet | 11 | 2022-03-11 | 2024-05-02 |
| Induction Optimization With Stelara for Crohn's Disease Ustekinumab - Crohn Disease | Phase 4 | Terminated | NYU Langone Health | 12 | 2022-02-16 | 2024-11-05 |
| Prevention of Recurrent Clostridium Difficile Infection (CDI) in Patients With Inflammatory Bowel Disease (IBD). Bezlotoxumab - Inflammatory Bowel Diseases, Ulcerative Colitis | Phase 4 | Terminated | David Binion, MD | 19 | 2021-10-14 | 2025-06-05 |
| Comparison of Contrast Agents in Liver Magnetic Resonance (MR) for the Detection of Hepatic Metastases Gadoxetate disodium, Gadobenate dimeglumine - Oligometastatic Disease, Liver Metastases | Phase 4 | Terminated | University of Colorado, Denver | 10 | 2021-06-22 | 2026-09-25 |
| A Study of Darvadstrocel in Adults With Crohn's Disease and Complex Perianal Fistula Darvadstrocel - Crohn's Disease, Complex Perianal Fistula | Phase 4 | Terminated | Takeda | 53 | 2020-12-22 | 2026-01-22 |
| Efficacy and Safety of Teicoplanin in CDAD TEICOPLANIN - Clostridium Difficile Infection-associated Diarrhea and Colitis | Phase 4 | Terminated | Sanofi | 50 | 2020-05-15 | 2025-09-23 |
| Loss of Response of Adalimumab Biosimilar vs Adalimumab Original, in Inflammatory Bowel Disease. Amgevita 40Mg Solution for Injection, HUMIRA 40Mg Solution for Injection - Crohn Disease, Ulcerative Colitis | Phase 4 | Terminated | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 24 | 2019-10-10 | 2021-01-12 |
| Budesonide in Patients With Immune Mediated Enteropathies Withdrawal of Oral Budesonide - Enteropathy, Celiac Disease | Phase 4 | Terminated | Mayo Clinic | 1 | 2019-09-10 | 2022-08-26 |
| TITRATE (inducTIon for acuTe ulceRATivE Colitis) Infliximab - Colitis, Ulcerative | Phase 4 | Terminated | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 50 | 2019-09-04 | 2025-02-06 |
| Comparing the Effectiveness of IV Bezlotoxumab Versus Placebo in Decreasing Morbidity and Mortality in Patients With Fulminant C. Diff Requiring Surgery. Bezlotoxumab, Normal Saline - Clostridia Difficile Colitis, Clostridium; Sepsis | Phase 4 | Terminated | Ohio State University | 5 | 2019-08-19 | 2026-06-18 |
| Shingrix Vaccine in Patients With Moderate to Severe Ulcerative Colitis on Tofacitinib SHINGRIX - Inflammatory Bowel Diseases | Phase 4 | Terminated | Boston Medical Center | 15 | 2019-07-31 | 2025-02-21 |
| Effectiveness of Vonoprazan vs Omeprazole as Empiric Therapy for Gastroesophageal Reflux Disease (GERD) Patients Without Alarm Features Vonoprazan, Omeprazole - GERD, Gastro Esophageal Reflux | Phase 4 | Terminated | St. Luke's Medical Center, Philippines | 82 | 2019-05-26 | 2023-11-22 |
| Antibiotic Duration in Post-appendectomy Abscess ampicillin/clavulanate - Complicated Appendicitis, Perforated Appendicitis | Phase 4 | Terminated | Phoenix Children's Hospital | 7 | 2019-05-01 | 2024-03-08 |
Showing 20 of 101. Sign in to see all of them.
Crohn Disease (19) · Colitis, Ulcerative (14) · Colorectal Neoplasms (9) · Inflammatory Bowel Diseases (9) · Gastroesophageal Reflux (8) · Gastroparesis (6) · Appendicitis (5) · Celiac Disease (3) · Hyperphagia (3) · Ileus (3) · Intestinal Obstruction (3) · Irritable Bowel Syndrome (3) · Neoplasm Metastasis (3) · Short Bowel Syndrome (3) · Barrett Esophagus (2)
Digestive System Diseases (101) · Intestinal Diseases (71) · Gastroenteritis (42) · Colonic Diseases (28) · Pathological Conditions, Signs and Symptoms (27) · Inflammatory Bowel Diseases (24) · Neoplasms (18) · Digestive System Neoplasms (16) · Esophageal Diseases (16) · Neoplasms by Site (16) · Gastrointestinal Neoplasms (15) · Signs and Symptoms (15) · Colitis (14) · Pathologic Processes (14)
Infliximab (5) · Prednisone (5) · Saline Solution (4) · Azathioprine (3) · Bevacizumab (3) · Cisapride (3) · Morphine (3) · Omeprazole (3) · Pantoprazole (3) · vedolizumab (3) · Adalimumab (2) · Adrenal Cortex Hormones (2) · Ketamine (2) · Lansoprazole (2) · Methylprednisolone (2)
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (4) · Mayo Clinic (3) · Pacira Pharmaceuticals, Inc (3) · Pfizer (3) · Takeda (3) · Baxter Healthcare Corporation (2) · Cedars-Sinai Medical Center (2) · Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa (2) · Merck Sharp & Dohme LLC (2) · Sanofi (2) · Shandong Cancer Hospital and Institute (2) · University of Western Ontario, Canada (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · AdventHealth (1) · American Institute for Voice and Ear Research (1)
United States (54) · Spain (8) · Germany (7) · France (6) · Netherlands (6) · Italy (5) · Canada (4) · Czechia (4) · South Korea (4) · China (3) · India (3) · Israel (3) · Poland (3) · Serbia (3) · Ukraine (3)
Jinming Yu, Ph.D, M.D (2) · Sergio Bergese, MD (2) · Abdullah Aljahdali, MD (1) · Abebe Haregewoin, MD, PhD (1) · Abed Allehibi, Dr (1) · Aharon Lerner, MD (1) · Ali Shariat, MD (1) · Ananya Das, MD (1) · Anjali Kumar, MD (1) · Anna H Lyra, PhD (1)
PMID 25018650, PMID 21336429, PMID 24814583, PMID 24953836, PMID 26559637, PMID 27480410, PMID 28119763, PMID 28497402, PMID 28567114, PMID 28646590, PMID 28894571, PMID 29739175, PMID 30504527, PMID 30802304, PMID 33210333, PMID 35648151, PMID 36124702, PMID 36687454, PMID 38412408, PMID 38425446, PMID 38778549, PMID 39241828, PMID 40013523, PMID 40028509, PMID 40357993, PMID 41258993, PMID 41684725, PMID 42669025
2014 (2), 2016 (2), 2017 (2), 2009 (1), 2015 (1), 2019 (1), P30CA046934 (1), R01DK125495 (1)