16 completed, 5 recruiting, 3 unknown, 1 not yet recruiting. 27 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 27 | Completed 16, Recruiting 5, Unknown 3, Not yet recruiting 1, Terminated 1, Withdrawn 1 |
Follow Fragility: new trials by email Literature Review of Fragility trials Research Report on Fragility
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Wireless MicroPremVitals Button Sensor in the NICU Wireless MicroPremVitals Button Sensor System - Premature Birth, Fragility | Not applicable | Recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 10 | 2026-06-19 | 2026-07-28 |
| Effects of VIVIFRAIL Program on Functional Capacity and Geriatric Syndromes in the Elderly. Behavioral: Vivifrail multicomponent physical exercise program - Fragility | Not applicable | Not yet recruiting | Elena Pérez Expósito, MD | 86 | 2026-03-16 | 2026-02-27 |
| IMPACT OF A MULTICOMPONENT PHYSICAL EXERCISE PROGRAM ON THE FUNCTIONAL CAPACITY OF PATIENTS ADMITTED TO AN INTERMEDIATE CARE HOSPITAL. VIVIFRAIL FOR A BETTER VIG-FRAIL. vivifrail - Functionality, Fragility | Not applicable | Recruiting | Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina | 120 | 2026-02-18 | 2026-06-09 |
| Sedation Methods in Percutaneous Transhepatic Biliary Drainage: Procedure Quality and Recovery Remifentanil, Ketamine - Fragility, Biliary Obstruction | Not applicable | Recruiting | Ankara City Hospital Bilkent | 98 | 2026-02-01 | 2026-06-10 |
| Impact of Nutritional Management on the Frailty of Patients Waiting for Liver Transplantation (Via the LFI Tool) Dietary management, No dietary management - Fragility, Cirrhosis | Not applicable | Recruiting | Hospices Civils de Lyon | 210 | 2025-06-30 | 2025-07-04 |
| EdOxaban in fRagIle Patients With Percutaneous Endoscopic GAstrostoMy and atrIal fIbrIllation Edoxaban, No Edoxaban - Atrial Fibrillation, Fragility | Not applicable | Unknown | Azienda Ospedaliero Universitaria Maggiore della Carita | 168 | 2024-02-01 | 2024-02-29 |
| Effect of a Dual-task Intervention Program on Physical and Cognitive Function Single-Task, Dual-Task - Functional Movement Disorder, Fragility | Not applicable | Unknown | University of Americas - Chili | 24 | 2023-11-08 | 2024-04-12 |
| Follow-up Strategies for Fragile Patients With Decompensated Heart Failure Management Program - Heart Failure; With Decompensation, Fragility | Not applicable | Terminated | Hospital Italiano de Buenos Aires | 37 | 2020-12-02 | 2022-12-09 |
| Biological Markers of Functional Effects of Physical Activity in an Elderly Population adapted physical activity - Fragility | Not applicable | Completed | Centre Hospitalier Universitaire de Nice | 92 | 2019-11-04 | 2023-11-18 |
| Motorized Platform and Autonomy Among the Frail and Pre-frail Older Adult (PLATAUTONOMIE) plate-forme Hu360® - Fragility | Not applicable | Withdrawn | University Hospital, Toulouse | 2019-06-01 | 2020-11-12 | |
| Multi-component Exercise Program and Nutritional Supplementation in Frail Older Adults Exercise plus nutritional suplementation, Exercise - Fragility | Not applicable | Completed | Cardenal Herrera University | 110 | 2019-05-30 | 2020-01-27 |
| Optimized Recovery After Trauma in Geriatric Patient gero-erat - Geriatric Assessment, Quality of Life | Not applicable | Recruiting | Vastra Gotaland Region | 540 | 2019-05-09 | 2024-11-25 |
| Prehabilitation of Frail Surgical Cancer Patients Using Remote Ischemic Preconditioning Remote Ischemic Preconditioning - Colon Cancer, Fragility | Not applicable | Completed | Medical College of Wisconsin | 17 | 2019-02-22 | 2024-09-19 |
| Impact of Increased Protein Density Diet to Muscle Mass and Strength Among Mid-aged and Older Adults 25% protein, 15% protein - Muscle Loss, Muscle Weakness | Not applicable | Completed | National Yang Ming Chiao Tung University | 70 | 2019-02-13 | 2020-02-27 |
| Effectiveness of Integrated Care Network Multi-domain intervention - Fragility, Multimorbidity | Not applicable | Completed | National Yang Ming Chiao Tung University | 398 | 2018-06-25 | 2020-04-21 |
| Reducing Readmission for Frail Elderly Patients With Decompensated Heart Failure Intervention Group, Control Group (Standard Care) - Heart Failure, Acute Decompensated Heart Failure | Not applicable | Completed | Jewish General Hospital | 60 | 2018-03-01 | 2022-10-14 |
| Effectiveness of a Multi-component Physical Training in Hyper-fragile Elders: A Randomized Clinical Trial Control Intervention, Multimodal Intervention - Multimodal Intervention, Fragility | Not applicable | Completed | University of Malaga | 114 | 2017-11-01 | 2024-06-04 |
| Effectiveness of Combined Aerobic and Strength Training in Acute and Chronic Adaptations in Patients With Heart Failure Combined Aerobic Training, Combined Strength Training - Chronic Heart Failure, Fragility | Not applicable | Completed | University of Lisbon | 28 | 2017-10-09 | 2019-09-27 |
| Prehabilitation in Frail Colon Cancer Prehabilitation - Colon Cancer, Fragility | Not applicable | Unknown | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | 40 | 2017-04-04 | 2019-09-18 |
| Efficacy of an Intervention to Prevent Frailty in Obese Elderly People (PRE-FROB) Intervention - Fragility, Sarcopenia | Not applicable | Completed | Consorci Sanitari del Maresme | 319 | 2017-01-23 | 2020-07-22 |
Showing 20 of 27. Sign in to see all of them.
Frailty (5) · Motor Activity (4) · Colonic Neoplasms (2) · Heart Failure (2) · Neoplasms (2) · Apnea (1) · Atrial Fibrillation (1) · Cholangitis (1) · Conversion Disorder (1) · Diabetes Mellitus (1) · Emergencies (1) · Fibrosis (1) · Hypertension (1) · Malnutrition (1) · Muscle Weakness (1)
Pathologic Processes (9) · Pathological Conditions, Signs and Symptoms (9) · Behavior (4) · Cardiovascular Diseases (4) · Digestive System Diseases (3) · Heart Diseases (3) · Nervous System Diseases (3) · Nutritional and Metabolic Diseases (3) · Signs and Symptoms (3) · Atrophy (2) · Colonic Diseases (2) · Colorectal Neoplasms (2) · Digestive System Neoplasms (2) · Gastrointestinal Diseases (2) · Gastrointestinal Neoplasms (2)
Control Groups (1) · Diet (1) · Exercise (1) · Ketamine (1) · Methods (1) · Preoperative Exercise (1) · Proteins (1) · Remifentanil (1) · Self-Management (1) · Standard of Care (1) · edoxaban (1)
Centre Hospitalier Universitaire de Nice (2) · National Yang Ming Chiao Tung University (2) · University Hospital, Toulouse (2) · Aarhus University Hospital (1) · Ankara City Hospital Bilkent (1) · Azienda Ospedaliero Universitaria Maggiore della Carita (1) · Cardenal Herrera University (1) · Cliniques universitaires Saint-Luc- Université Catholique de Louvain (1) · Consorci Sanitari del Maresme (1) · Coordinación de Investigación en Salud, Mexico (1) · Elena Pérez Expósito, MD (1) · Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina (1) · Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (1) · Hospices Civils de Lyon (1) · Hospital Italiano de Buenos Aires (1)
Spain (6) · France (4) · Canada (2) · Taiwan (2) · United States (2) · Argentina (1) · Belgium (1) · Chile (1) · Denmark (1) · Italy (1) · Mexico (1) · Portugal (1) · Sweden (1) · Turkey (Türkiye) (1)
Liang-Kung Chen, MD.PhD. (2) · Dmitri Zintchouk, MD (1) · Donna Tilley, PhD (1) · Else Marie Damsgaard, MD, DMSc (1) · Guilherme Sant'Anna, MD, PhD (1) · Javier Gallego, PhD (1) · Jonathan Afilalo, FRCPC (1) · Julie K Freed, MD, Ph.D. (1)
PMID 28582238, PMID 29395938, PMID 31226936, PMID 33228950, PMID 34002975, PMID 34417416, PMID 35588252, PMID 36098028, PMID 36260404, PMID 37162250, PMID 37949432
R21AG062933 (1)