22 completed, 5 terminated, 1 active not recruiting, 1 recruiting. 7 Phase 2, 5 Phase 1, 3 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 5, Active not recruiting 1, Terminated 1 |
| Phase 1 | 5 | Completed 4, Active not recruiting 1 |
| Not applicable | 3 | Completed 2, Recruiting 1 |
| Phase 4 | 1 | Completed 1 |
Follow Focal Dystonia: new trials by email Literature Review of Focal Dystonia trials Research Report on Focal Dystonia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Neuromodulation in Laryngeal Dystonia repetitive transcranial magnetic stimulation (rTMS), sham rTMS - Laryngeal Dystonia, Focal Dystonia | Not applicable | Recruiting | MGH Institute of Health Professions | 25 | 2021-06-10 | 2026-02-20 |
| Characterization of Manual Dexterity by Finger Force Manipuladum (FFM) in Patients With Writer's Cramp and in Control Subjects Finger Force Manipuladum (FFM) - Dystonic Disorder, Focal Dystonia | Not applicable | Completed | Fondation Ophtalmologique Adolphe de Rothschild | 40 | 2018-10-01 | 2021-06-22 |
| Non-Motor Features of Cervical Dystonia (CD) Neurological Examination, Assessment of Non-Motor Features - Cervical Dystonia, Movement Disorders | Completed | Vanderbilt University Medical Center | 33 | 2018-03-26 | 2020-02-07 | |
| Deep Brain Stimulation Surgery for Focal Hand Dystonia DBS surgery, Medtronic Activa Rechargeable System - Dystonia, Focal Dystonia | Phase 1 / Phase 2 | Active not recruiting | National Institute of Neurological Disorders and Stroke (NINDS) | 5 | 2018-01-17 | 2026-10-16 |
| Electrophysiological and Neuroimaging Correlates of the Effect of Zolpidem in Patients With Focal Dystonia Zolpidem, Placebo - Focal Dystonia | Phase 1 | Completed | University Medical Centre Ljubljana | 24 | 2017-09-30 | 2023-12-04 |
| Loss of Depotentiation in Focal Dystonia PAS25, PAS10, PAS25-cTBS150 - Focal Dystonia, Healthy Volunteers | Terminated | National Institute of Neurological Disorders and Stroke (NINDS) | 6 | 2017-09-20 | 2020-05-06 | |
| Neurophysiologic Study of Patient With Essential Tremor and Dystonic Tremor Essential Tremor, Cervical Dystonia | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 2 | 2017-04-07 | 2018-08-01 | |
| Cholinergic Receptor Imaging in Dystonia [18F]FP-TZTP - Cervical Dystonia, Dystonia | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 31 | 2016-12-16 | 2026-10-16 | |
| Compare Two Guidance Techniques for Botulinum Toxin Injections for the Treatment of Limb Spasticity and Focal Dystonia Electrical stimulation, Ultrasound - Spasticity, Focal Dystonia | Not applicable | Completed | Icahn School of Medicine at Mount Sinai | 20 | 2015-10-28 | 2021-11-26 |
| Depotentiation in People With Focal Hand Dystonia Focal Dystonia, Healthy Volunteers | Terminated | National Institute of Neurological Disorders and Stroke (NINDS) | 6 | 2014-03-05 | 2017-07-02 | |
| Acetyl Hexapeptide-8 for Blepharospasm Topical acetyl hexapeptide-8, Placebo - Focal Dystonia | Phase 2 | Terminated | National Institute of Neurological Disorders and Stroke (NINDS) | 8 | 2012-11-01 | 2016-11-10 |
| rTMS and Retraining in Focal Hand Dystonia Repetitive Transcranial Magnetic Stimulation, Sensorimotor Retraining, Non-specific Therapy - Focal Dystonia | Phase 1 / Phase 2 | Completed | University of Minnesota | 9 | 2011-11-01 | 2019-11-18 |
| Genetics of Motor Learning Parkinson s Disease, Dystonic Disorders | Terminated | National Institute of Neurological Disorders and Stroke (NINDS) | 5 | 2010-04-14 | 2019-11-22 | |
| A Study of Acetyl Hexapeptide-8 (AH8) in Treatment of Blepharospasm Acetyl-Hexapeptide Topical Treatment, placebo - Focal Dystonia | Phase 1 / Phase 2 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 24 | 2009-07-01 | 2012-09-06 |
| Role of Neurotransmission and Functional CNS Networks in Spasmodic Dysphonia Spasmodic Dysphonia, Focal Dystonia | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 37 | 2008-07-09 | 2018-07-05 | |
| Association Between Focal Dystonia and Complex Regional Pain Syndrome Focal Dystonia, Peripheral Nervous System Disease | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 90 | 2007-12-21 | 2017-07-02 | |
| Motor and Premotor Cortex Stimulation for Treatment of Secondary Focal Dystonia With Striato Palliadal Lesion : Evaluation of Safety and Effectiveness Implantation of neurostimulators and their auxiliary components - Focal Dystonia | Phase 1 | Completed | University Hospital, Clermont-Ferrand | 5 | 2007-09-01 | 2014-07-08 |
| Brain Changes in Blepharospasm Dystonia, Focal Dystonia | Terminated | National Institute of Neurological Disorders and Stroke (NINDS) | 47 | 2007-06-12 | 2019-12-16 | |
| Brain Stimulation to Treat Blepharospasm or Meige Syndrome repetitive transcranial magnetic stimulation (rTMS) - Blepharospasm, Focal Dystonia | Phase 2 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 22 | 2006-06-22 | 2017-07-02 |
| fMRI Studies of Task Specificity in Focal Hand Dystonia Focal Dystonia | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 51 | 2006-03-30 | 2017-07-02 |
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Dystonic Disorders (29) · Dystonia (11) · Dystonia, Focal, Task-Specific (10) · Movement Disorders (7) · Blepharospasm (4) · Torticollis (4) · Dysphonia (3) · Tremor (2) · Voice Disorders (2) · Brain Injuries (1) · Cerebellar Diseases (1) · Complex Regional Pain Syndromes (1) · Essential Tremor (1) · Inhibition, Psychological (1) · Muscle Hypotonia (1)
Central Nervous System Diseases (29) · Nervous System Diseases (28) · Movement Disorders (22) · Pathological Conditions, Signs and Symptoms (17) · Dyskinesias (16) · Neurologic Manifestations (16) · Signs and Symptoms (16) · Eye Diseases (4) · Eyelid Diseases (4) · Brain Diseases (3) · Dystonia (3) · Laryngeal Diseases (3) · Otorhinolaryngologic Diseases (3) · Respiratory Tract Diseases (3) · Neuromuscular Manifestations (2)
Transcranial Magnetic Stimulation (3) · Amlodipine (1) · Botulinum Toxins (1) · Constraint Induced Movement Therapy (1) · Electric Stimulation (1) · Massage (1) · Neurologic Examination (1) · Transcutaneous Electric Nerve Stimulation (1) · Ultrasonography (1) · Zolpidem (1) · acetyl-glutamyl-glutamyl-methionyl-glutaminyl-arginyl-argininamide (1) · rimabotulinumtoxinB (1)
National Institute of Neurological Disorders and Stroke (NINDS) (21) · Columbia University (1) · Fondation Ophtalmologique Adolphe de Rothschild (1) · Icahn School of Medicine at Mount Sinai (1) · MGH Institute of Health Professions (1) · University Hospital, Clermont-Ferrand (1) · University Medical Centre Ljubljana (1) · University of Minnesota (1) · Vanderbilt University Medical Center (1)
United States (26) · France (1) · Serbia (1) · Slovenia (1)
Mark Hallett, M.D. (7) · Codrin I Lungu, M.D. (1) · David Simpson, MD (1) · Debra J Ehrlich, M.D. (1) · Kenneth H Fischbeck, M.D. (1) · Sandra B Martin (1) · Seth Pullman, MD (1) · Silvina G Horovitz, Ph.D. (1) · Teresa J Kimberley, PhD, PT (1) · Teresa J Kimberley, PhD,PT (1)
K24DC018603 (1)