176 completed, 53 recruiting, 53 unknown, 30 active not recruiting. 104 Not applicable, 83 Phase 2, 44 Phase 1, 38 Phase 3, 7 Phase 4.
Follow Cerebellar Diseases: new trials by email Literature Review of Cerebellar Diseases trials Research Report on Cerebellar Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Umbilical Cord Mesenchymal Stem Cells Therapy (19#iSCLife®-SA) for Patients With Spinocerebellar Ataxia Intravenous infusion, Intrathecal injection, umbilical cord mesenchymal stem cell - Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 2 | Phase 2 | Not yet recruiting | Sclnow Biotechnology Co., Ltd. | 45 | 2026-12-31 | 2026-04-23 |
| Multi-Modal Digital Monitoring of Disease Symptoms in Spinocerebellar Ataxia Spinocerebellar Ataxia (SCA) | Not yet recruiting | BioSensics | 25 | 2026-12-15 | 2026-10-01 | |
| GV101 for Friedreich's Ataxia (FA) Treatment GV101, Placebo - Friedreich's Ataxia | Phase 2 | Not yet recruiting | Graviton Bioscience Corporation | 48 | 2026-11-01 | 2026-10-15 |
| A Study to Evaluate the Efficacy and Safety of Subcutaneous Nomlabofusp in Subjects With Friedreich's Ataxia Nomlabofusp, Placebo - Friedreich Ataxia, Friedreich's Ataxia | Phase 3 | Recruiting | Larimar Therapeutics, Inc. | 150 | 2026-10-26 | 2026-10-09 |
| A Study to Learn How BIIB141 (Omaveloxolone) Affects the Health of Participants With Friedrich's Ataxia Who Took it During Pregnancy and/or During Breastfeeding and About the Health of Their Babies Omaveloxolone - Friedreich Ataxia | Recruiting | Biogen | 10 | 2026-10-26 | 2026-07-10 | |
| A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ATI-105 in Healthy Adults ATI-105, Placebo - Friedreich Ataxia, Cardiomyopathies | Phase 1 | Not yet recruiting | Adjuvia Therapeutics, Inc. | 60 | 2026-10-26 | 2026-10-09 |
| A Study to Learn More About Friedrich's Ataxia in People Living in the Gulf Cooperation Council (GCC) Region of the World Friedreich's Ataxia | Not yet recruiting | Biogen | 40 | 2026-10-15 | 2026-10-21 | |
| Neoadjuvant Pembrolizumab and Porustobart in Resectable pMMR/MSS Colon Cancer Pembrolizumab, Porustobart - Colon Cancer | Phase 2 | Recruiting | Solstice Oncology, Inc. | 100 | 2026-09-30 | 2026-10-22 |
| Biomarkers for Babies and Young Children With Ataxia Telangiectasia Ataxia Telangiectasia | Not yet recruiting | University of Nottingham | 56 | 2026-09-01 | 2026-07-16 | |
| Rare Disease Registry Database for Movement Disorders in Southern Anhui Province Motor Neuron Diseases, Spinocerebellar Ataxias | Active not recruiting | First Affiliated Hospital of Wannan Medical College | 180 | 2026-08-25 | 2026-09-24 | |
| Pivotal Study of N-acetyl-L-leucine for CACNA1A N-Acetyl-L-Leucine, Placebo - CACNA1A, Spinocerebellar Ataxia Type 6 | Phase 3 | Recruiting | IntraBio Inc | 60 | 2026-08-17 | 2026-09-08 |
| Long-Term Efficacy Study of Vatiquinone for the Treatment of Friedreich's Ataxia (FA) Vatiquinone - Friedreich's Ataxia | Phase 3 | Not yet recruiting | PTC Therapeutics | 120 | 2026-08-15 | 2026-08-14 |
| Optimizing Parameters of Transcranial Temporal Interference Stimulation for Spinocerebellar Ataxia Type 3 Transcranial Temporal Interference Stimulation (tTIS) - Spinocerebellar Ataxia Type 3 | Not applicable | Not yet recruiting | First Affiliated Hospital of Fujian Medical University | 24 | 2026-08-07 | 2026-09-01 |
| Safety and Efficacy of Mutation-targeted Precision Genetic Therapy for Ataxia-Telangiectasia (A-T) Antisense oligonucleotide targeting the ATM gene - Ataxia Telangiectasia | Phase 1 / Phase 2 | Recruiting | Timothy Yu | 10 | 2026-08-01 | 2026-05-28 |
| FOLFIRI Plus Bevacizuamb and QL1706 in Second-Line Treatment for mCRC FOLFIRI + bevacizumab + QL1706, FOLFIRI + bevacizumab - Colorectal Cancer Metastatic, Microsatellite Stable (MSS) Colorectal Cancer (CRC) | Phase 3 | Not yet recruiting | Sun Yat-sen University | 270 | 2026-07-30 | 2026-07-27 |
| Digital Outcome Assessment Using AI Active Gaming and Motion Capture in Friedreich Ataxia Laboratory validation session (VSimulator), Home-based active gaming assessment - Friedreich Ataxia | Not yet recruiting | University of Exeter | 40 | 2026-07-30 | 2026-07-28 | |
| Cardiac Output and Fatigue in Friedreich's Ataxia Aerobic Exercise - Friedreich's Ataxia | Not applicable | Recruiting | Scott Barbuto | 30 | 2026-07-15 | 2026-09-22 |
| Individualized Neuro-Modulation Paired With Cerebellar Therapy Therapy - Cerebellar Ataxia, Cerebellar Diseases | Not applicable | Recruiting | Hugo W. Moser Research Institute at Kennedy Krieger, Inc. | 30 | 2026-06-30 | 2026-06-11 |
| Study of LX2006 Gene Therapy in Friedreich Ataxia Cardiomyopathy LX2006, Usual Care - Friedreich Ataxia, Cardiomyopathy, Secondary | Phase 2 | Recruiting | Lexeo Therapeutics | 26 | 2026-06-25 | 2026-09-02 |
| Variable Intense Training for Ataxia and Locomotion High-intensity training in variable contexts, Conventional balance training - Cerebellar Disorders, Cerebellar Degeneration | Not applicable | Not yet recruiting | Indiana University | 20 | 2026-06-15 | 2026-06-02 |
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Friedreich Ataxia (110) · Spinocerebellar Ataxias (92) · Cerebellar Ataxia (69) · Ataxia (49) · Spinocerebellar Degenerations (49) · Ataxia Telangiectasia (42) · Machado-Joseph Disease (32) · Colorectal Neoplasms (12) · Neurodegenerative Diseases (11) · Cardiomyopathies (10) · Multiple System Atrophy (10) · Parkinson Disease (10) · Rare Diseases (9) · Genetic Diseases, Inborn (8)
Brain Diseases (359) · Central Nervous System Diseases (358) · Nervous System Diseases (356) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (299) · Genetic Diseases, Inborn (290) · Heredodegenerative Disorders, Nervous System (259) · Neurodegenerative Diseases (257) · Spinal Cord Diseases (257) · Neurologic Manifestations (218) · Dyskinesias (216) · Spinocerebellar Degenerations (205) · Ataxia (166) · Nutritional and Metabolic Diseases (156) · Metabolic Diseases (154)
Blood Specimen Collection (9) · Transcranial Magnetic Stimulation (8) · alpha-tocotrienol quinone (7) · idebenone (7) · pembrolizumab (7) · omaveloxolone (6) · Transcranial Direct Current Stimulation (5) · Magnetic Resonance Spectroscopy (4) · acetylleucine (4) · interferon gamma-1b (4) · Bevacizumab (3) · Deep Brain Stimulation (3) · Fluorouracil (3) · Immunoglobulins, Intravenous (3) · Leucovorin (3)
Kissei Pharmaceutical Co., Ltd. (9) · National Institute of Neurological Disorders and Stroke (NINDS) (9) · Larimar Therapeutics, Inc. (8) · Biogen (7) · Institut National de la Santé Et de la Recherche Médicale, France (7) · University of Florida (7) · University of South Florida (7) · Children's Hospital of Philadelphia (6) · IRCCS Eugenio Medea (6) · Johann Wolfgang Goethe University Hospital (6) · PTC Therapeutics (6) · Assistance Publique - Hôpitaux de Paris (5) · Chang Gung University (5) · Columbia University (5) · Hospital de Clinicas de Porto Alegre (5)
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