8 completed, 3 unknown, 1 not yet recruiting. 10 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 8, Unknown 2 |
Follow Lateral Internal Sphincterotomy: new trials by email Literature Review of Lateral Internal Sphincterotomy trials Research Report on Lateral Internal Sphincterotomy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Topical Nitroglycerin Versus Lateral Internal Sphincterotomy for Chronic Anal Fissure Topical 0.2% Glyceryl Trinitrate (Nitroglycerin) Ointment, Lateral Internal Sphincterotomy - Chronic Anal Fissure | Not applicable | Completed | Sheikh Zayed Federal Postgraduate Medical Institute | 72 | 2026-06-15 | 2026-10-21 |
| Comparison of Botulinum Toxin Injection and Lateral Internal Sphincterotomy in Chronic Anal Fissure Management Botulinum Toxin Type A (BOTOX) Injection, Lateral Internal Sphincterotomy - Anal Fissure Chronic | Not applicable | Completed | Islamabad Medical and Dental College | 90 | 2026-03-02 | 2026-08-13 |
| RELIEF Study: Resolving Fissures With Lateral Internal Sphincterotomy Lateral Internal Sphincterotomy (LIS) - Chronic Anal Fissure | Not yet recruiting | Turkish Society of Colon and Rectal Surgery | 300 | 2025-06-01 | 2025-05-22 | |
| Hemorrhoidectomy With or Without Lateral Internal Sphincterotomy in Management of Patients With Hemorrhoids Hemorrhoidectomy with lateral internal sphincterotomy, Hemorrhoidectomy - Lateral Internal Sphincterotomy, Hemorrhoidectomy | Not applicable | Completed | Minia University | 200 | 2024-12-20 | 2026-09-03 |
| Hemorrhoidectomy Only Versus Hemorrhoidectomy With Lateral Internal Sphincterotomy lateral internal sphincterotomy - Hemorrhoids | Not applicable | Unknown | Assiut University | 20 | 2024-08-31 | 2024-09-19 |
| The Effect of Botulinum Toxin Injection After Hemorrhoidectomy in Pain Control. Botox Injectable Product, Internal sphincterotomy - Pain, Haemorriodectomy | Not applicable | Completed | Mansoura University | 60 | 2021-12-01 | 2023-06-08 |
| Effectiveness of Anal Enlargement by Dilators as a Therapeutic Physical Tool in Acute Anal Fissure Anal dilators, lateral internal sphincterotomy - Acute Anal Fissure | Not applicable | Unknown | Sheba Medical Center | 75 | 2021-05-01 | 2021-04-02 |
| High Dose Multiple Site Injection of Botox Versus Lateral Sphincterotomy in Chronic Analfissure botox injection in intersphincteric space, lateral internal sphincterotomy - Chronic Anal Fissure | Not applicable | Completed | Zagazig University | 96 | 2017-06-01 | 2019-11-21 |
| Posterolateral Versus Lateral Internal Anal Sphincterotomy for Chronic Anal Fissure posterolateral sphincterotomy, lateral sphincterotomy - Anal Fissure | Not applicable | Completed | Mansoura University | 80 | 2015-01-01 | 2018-02-09 |
| Transcutaneous Posterior Tibial Nerve Stimulation for Treatment of Chronic Anal Fissure lateral internal sphincterotomy, TENS - Chronic Anal Fissure | Not applicable | Completed | Mansoura University | 94 | 2012-07-01 | 2015-03-24 |
| Ultrasound Guided Lateral Sphincterotomy: Long Term Results lateral sphincterotomy, ultrasound guided lateral sphincterotomy - Focus: Anal Incontinence After Lateral Sphincterotomy for Chronic Anal Fissure | Unknown | Hvidovre University Hospital | 28 | 2007-10-01 | 2015-03-20 | |
| Idiopathic Hypertensive Anal Canal: a Place of Internal Sphincterotomy lateral internal sphincterotomy (LIS), Glycerin trinitrate (GTN), botulinum toxin injection (BTX A) - Hypertensive Anal Canal | Not applicable | Completed | Mansoura University | 63 | 2002-09-01 | 2009-06-25 |
Fissure in Ano (3) · Hemorrhoids (2) · Fecal Incontinence (1) · Pain (1)
Mansoura University (4) · Assiut University (1) · Hvidovre University Hospital (1) · Islamabad Medical and Dental College (1) · Minia University (1) · Sheba Medical Center (1) · Sheikh Zayed Federal Postgraduate Medical Institute (1) · Turkish Society of Colon and Rectal Surgery (1) · Zagazig University (1)
Egypt (5) · Pakistan (2) · Denmark (1)
Dan Carter (1) · Sameh H Emile, M.D. (1)
PMID 10395629, PMID 14769323, PMID 15657647, PMID 26316154, PMID 29779044, PMID 7069679