17 completed, 8 unknown, 6 recruiting, 4 withdrawn. 27 Not applicable, 2 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 27 | Completed 10, Recruiting 5, Unknown 4, Not yet recruiting 3, Withdrawn 3, Terminated 2 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
| Phase 4 | 1 | Withdrawn 1 |
Follow Eustachian Tube Dysfunction: new trials by email Literature Review of Eustachian Tube Dysfunction trials Research Report on Eustachian Tube Dysfunction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Active vs. Passive VR During Office-based ENT Procedures Passive virtual reality headset or goggles, Active virtual reality headset or goggles - Pain, Anxiety | Not applicable | Not yet recruiting | Cedars-Sinai Medical Center | 132 | 2026-09-01 | 2026-08-17 |
| EarFlo: A Non-Invasive Treatment for Otitis Media With Effusion & Eustachian Tube Dysfunction in Adults EarFlo Device - Otitis Media With Effusion (OME), Eustachian Tube Dysfunction | Not applicable | Not yet recruiting | Philip Perez | 100 | 2026-08-27 | 2026-08-20 |
| Nasal Dilator Therapy for Patulous Eustachian Tube Dysfunction Internal nasal dilator - Patulous Eustachian Tube Dysfunction, Eustachian Tube Dysfunction | Not applicable | Recruiting | The Methodist Hospital Research Institute | 50 | 2026-04-22 | 2026-08-31 |
| Buteyko Breathing and Approach of Smoking Hygiene: Effects on Dysfucntion of Eustachian Tube and Lung Functions Buteyko breathing plus smoking hyeigne approach, smoking hygiene appraoch - Tobacco Smoking, Eustachian Tube Dysfunction | Not applicable | Recruiting | Cairo University | 40 | 2025-09-15 | 2025-11-19 |
| Hearing/ET/Vestibular in Balloon Pilots Non-invasive audiologic and vestibular assessments - Hearing Loss, Noise-Induced, Eustachian Tube Dysfunction | Completed | Gaziosmanpasa Research and Education Hospital | 105 | 2025-09-04 | 2026-01-21 | |
| Efficacy of Buteyko Breathing in Seniors With Chronic Eustachian Tube Dysfunction Buteyko breathing, usual care - Eustachian Tube Dysfunction | Not applicable | Recruiting | Cairo University | 40 | 2025-05-12 | 2025-09-25 |
| Evaluation of Eustachian Tube Function With 226 and 1000 Hz Probes in Children Undergoing Tonsillectomy ± Adenoidectomy Eustachian tube function test with 226 and 1000 Hz probes - Tonsillar Hypertrophy, Eustachian Tube Dysfunction | Completed | Sumeyra DOLUOGLU | 128 | 2024-08-20 | 2025-04-15 | |
| Long-term Assessment of Balloon Eustachian Tuboplasty for Obstructive Eustachian Tube Disease Balloon Eustachian Tuboplasty (BET) under general anesthesia., Insertion of catheter for probing and flushing the Eustachian tube under general anesthesia - Eustachian Tube Dysfunction | Not applicable | Not yet recruiting | University Hospital, Montpellier | 96 | 2023-10-01 | 2023-09-21 |
| Efficacy of Balloon Dilation of the Eustachian Tube in Eustachian Tube Dilatory Dysfunction Balloon dilation of eustachian tube, Sham procedure - Eustachian Tube Dysfunction, Barotitis | Not applicable | Recruiting | University of Calgary | 76 | 2023-06-25 | 2025-04-03 |
| The Accuracy of Sonotubometry to Assess the Eustachian Tube Sonotubometry Assessment - Eustachian Tube Dysfunction | Not applicable | Unknown | James Tysome | 28 | 2023-04-21 | 2023-05-06 |
| The Evaluation of Eustachian Tube Function and Its Influencing Factors After Snoring Operation in Children Operation for snoring in children - Adenoidectomy, Tonsillectomy | Unknown | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 450 | 2022-10-18 | 2022-10-31 | |
| FFP3 Respirators and Ears - Effects on Middle Ear Pressure and Hearing FFP3 Mask - Eustachian Tube Dysfunction, Hearing Disorders | Not applicable | Unknown | Liverpool University Hospitals NHS Foundation Trust | 12 | 2022-07-23 | 2022-05-31 |
| Effect of Novel Exhalational Delivery System With Fluticasone (EDS-FLU) on Eustachian Tube Dysfunction (ETD) Fluticasone Propionate 93 MCG/1 ACTUATION Nasal Spray, Placebo Nasal Spray - Eustachian Tube Dysfunction | Phase 2 | Recruiting | Cedars-Sinai Medical Center | 80 | 2022-04-20 | 2026-03-11 |
| Pretympanoplasty Assessment of Patency and Mucociliary Function of Eustachian Tube Saccharin test - Eustachian Tube Dysfunction | Unknown | Assiut University | 50 | 2022-02-28 | 2022-02-08 | |
| Balloon Dilation of the Eustachian Tube Balloon dilation of the eustachian tube - Eustachian Tube Dysfunction | Not applicable | Terminated | Sunnybrook Health Sciences Centre | 15 | 2022-02-24 | 2023-09-08 |
| Effect of Rate (Slope) of Compression on the Incidence of Symptomatic ETD and MEB: a Phase III Prospective Study. Compression Profile/Schedule: 15 minute Non-Linear compression from start of the daily treatment until treatment pressure is reached (45 fsw), Compression Profile/Schedule: 15 minute Linear compression from start of the daily treatment until treatment pressure is reached (45 fsw) - Ear Barotrauma, Middle Ear Disease | Not applicable | Completed | Northwell Health | 1553 | 2021-10-01 | 2026-06-09 |
| Balloon Sinuplasty Efficiency in Maxillary Rhinosinusitis. Balloon sinuplasty of maxillary sinuses, Sham surgery - Maxillary Sinusitis, Sinusitis, Chronic | Not applicable | Recruiting | Tampere University Hospital | 120 | 2021-06-01 | 2022-10-20 |
| Ph.D.-Project: Eustachian Tube Dysfunction: Causes, Diagnosis, Treatment, and Prognosis Balloon Eustachian Tuboplasty - Eustachian Tube Dysfunction, Middle Ear Disease | Not applicable | Unknown | Regional Hospital West Jutland | 50 | 2021-06-01 | 2023-11-30 |
| Eustachian Tube Dilation With an Endovascular Balloon Eustachian tube dilation - Eustachian Tube Dysfunction, Eustachian Tube Dysfunction of Both Ears | Not applicable | Completed | Sunnybrook Health Sciences Centre | 12 | 2021-03-29 | 2022-10-26 |
| SinuSonic for ETD and Facial Pain: Acoustic Vibration + Oscillating Expiratory Pressure SinuSonic Device - Eustachian Tube Dysfunction, Facial Pain | Not applicable | Completed | Medical University of South Carolina | 30 | 2020-04-28 | 2026-02-13 |
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Otitis Media (3) · Otitis Media with Effusion (3) · Gastroesophageal Reflux (2) · Hearing Loss (2) · Hypersensitivity (2) · Nasal Obstruction (2) · Pressure Ulcer (2) · Wounds and Injuries (2) · Anxiety Disorders (1) · Bronchiolitis Obliterans Syndrome (1) · Disease (1) · Dizziness (1) · Dysphonia (1) · Ear Diseases (1) · Earache (1)
Otorhinolaryngologic Diseases (14) · Ear Diseases (11) · Pathological Conditions, Signs and Symptoms (10) · Neurologic Manifestations (8) · Signs and Symptoms (8) · Nervous System Diseases (6) · Otitis (5) · Respiratory Tract Diseases (5) · Sensation Disorders (5) · Hearing Disorders (3) · Immune System Diseases (3) · Nose Diseases (3) · Respiration Disorders (3) · Airway Obstruction (2) · Deglutition Disorders (2)
Acoustic Impedance Tests (1) · Appointments and Schedules (1) · Catheterization (1) · Diet, Sodium-Restricted (1) · Diuretics (1) · Eye Protective Devices (1) · Fluticasone (1) · Hearing (1) · Histamine Antagonists (1) · Laryngoscopy (1) · Omeprazole (1) · Pantoprazole (1) · Ranitidine (1) · Surgical Procedures, Operative (1) · Tympanoplasty (1)
University of Pittsburgh (3) · Cairo University (2) · Cedars-Sinai Medical Center (2) · Entellus Medical, Inc. (2) · Northwell Health (2) · Sunnybrook Health Sciences Centre (2) · Assiut University (1) · Cambridge University Hospitals NHS Foundation Trust (1) · Columbia University (1) · Cuneyt M. Alper (1) · Eye & ENT Hospital of Fudan University (1) · Gaziosmanpasa Research and Education Hospital (1) · Hillel Yaffe Medical Center (1) · Integra LifeSciences Corporation (1) · James Tysome (1)
United States (17) · Canada (3) · United Kingdom (3) · China (2) · Egypt (2) · Turkey (Türkiye) (2) · Denmark (1) · Finland (1) · South Korea (1)
Cuneyt M Alper, MD (4) · Ali MA Ismail, lecturer (2) · Owen J O'Neill, MD, MPH (2) · Ana Kim, MD (1) · Arthur Wu, MD (1) · David Dayya, DO, PhD, MPH (1) · David Yen, MD (1) · Dennis Poe, MD, PhD (1) · Edward D McCoul, MD, PhD (1) · Hao Xiong (1) · Helen X Xu, MD (1) · James Rainsbury, BMBS MSc FRCS (1) · James Tysome, Dr (1)
PMID 40008607, PMID 29912819, PMID 20564474, PMID 22344711, PMID 22500063, PMID 23728660, PMID 25215457, PMID 28372527, PMID 32247766, PMID 33640801, PMID 34390625, PMID 34840034, PMID 36855202, PMID 37992408, PMID 40276950, PMID 40663994, PMID 41817520, PMID 42310698
P50DC007667 (3), R21DC013167 (1)