43 completed, 17 unknown, 8 not yet recruiting, 7 recruiting. 40 Not applicable, 12 Phase 3, 4 Phase 2, 4 Phase 4, 1 Early Phase 1.
Follow Otitis Media with Effusion: new trials by email Literature Review of Otitis Media with Effusion trials Research Report on Otitis Media with Effusion
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Short-term Application of Lactoferrin Ventilation Tubes Ventilation tube insertion - Otitis Media With Effusion (OME) | Not applicable | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 20 | 2026-10-25 | 2026-11-03 |
| Towards Implementation of Universal Newborn Hearing Screening in Kenya Hearing and ear health screening - Hearing Loss, Bilateral or Unilateral, Otitis Media With Effusion in Children | Not applicable | Recruiting | University of Washington | 400 | 2026-09-24 | 2026-10-16 |
| EarFlo: A Non-Invasive Treatment for Otitis Media With Effusion & Eustachian Tube Dysfunction in Adults EarFlo Device - Otitis Media With Effusion (OME), Eustachian Tube Dysfunction | Not applicable | Not yet recruiting | Philip Perez | 100 | 2026-08-27 | 2026-08-20 |
| Osteopathic Manipulative Treatment for Children With Chronic or Recurrent Otitis Media Experimental Osteopathic Manipulative Treatment (OMT) Protocol, Control Osteopathic Manipulative Treatment (OMT) Protocol - Otitis Media, Otitis Media Effusion | Not applicable | Not yet recruiting | Sarah Vidal | 200 | 2026-08-01 | 2026-06-10 |
| CLIKX® Tympanostomy Tube Delivery System for the Placement of Tympanostomy Tubes CLiKX® Tympanostomy Tube Delivery System - Otitis Media, Otitis Media Chronic | Not applicable | Recruiting | ClinQure, Inc. | 80 | 2026-07-07 | 2026-11-03 |
| SWIR Otoscopy Study SWIR device - Otitis Media, Otitis Media Chronic | Not applicable | Recruiting | Stanford University | 100 | 2026-04-30 | 2026-07-24 |
| Evaluating Laser Otoscope for Middle Ear Effusion Detection Laser otoscope examination - Middle Ear Effusion, Otitis Media | Not yet recruiting | MSTATT LLC | 150 | 2026-03-01 | 2026-03-06 | |
| Validating and AI Software for Assessment of Children With Ear Concerns Otalgia, Otitis Media | Not yet recruiting | Glimpse Diagnostics, Inc. | 658 | 2026-01-01 | 2025-11-21 | |
| Laser Acupuncture for Otitis Media With Effusion in Children Laser Acupuncture, Sham Laser Acupuncture - Otitis Media With Effusion | Not applicable | Completed | Universitas Indonesia | 32 | 2025-12-29 | 2026-06-04 |
| Gamified Training and AI Support for Improving Ear Infection Diagnosis in Primary Care AOM Dx Trainer (gamified educational program), No Intervention - Standard Care - Otitis Media Acute, Otitis Media Effusion | Not applicable | Not yet recruiting | Vastra Gotaland Region | 200 | 2025-12-01 | 2025-11-24 |
| Intranasal Corticosteroid Spray for Preventing Otitis Media With Effusion After Radiotherapy in Nasopharyngeal Carcinoma Triamcinolone Acetonide, Placebo - Otitis Media, Otitis Media With Effusion After Nasopharyngeal Carcinoma | Phase 3 | Not yet recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 168 | 2025-10-01 | 2025-09-29 |
| Omega-3-Based Nutraceutical Supplementation as Adjunctive Therapy in Adults With Otitis Media With Effusion: A Multicenter, Double-Blind, Randomized Placebo-Controlled Trial Omega-3-based nutraceutical combination (Otoair Flogo), Bilastine 20 mg, Placebo Tablet or Capsule - Otits Media With Effusion | Phase 4 | Completed | Isola Tiberina - Gemelli Isola Hospital, Rome, Italy | 501 | 2025-10-01 | 2026-07-23 |
| Balloon Dilation of Eustachian Tube Versus Tympanostomy Tube in Management of Pediatric Obstructive Eustachian Tube Dysfunction eustachian tube dilatation, tympanostomy tube insertion - Otitis Media Effusion | Not applicable | Completed | Mansoura University | 44 | 2025-07-15 | 2026-10-27 |
| It is Accepted That Adenoid Hypertrophy is Related to Otitis Media With Effusion Incidence. Better Understanding of the Correlation Between the Relative Size of AH and the Incidence of Persistent OME May Provide Evidence to Support a More Standardized Approach to the Diagnosis and Treatment of OME. Adenoid Hypertrophy, Middle Ear Effusion | Not yet recruiting | Assiut University | 60 | 2025-05-01 | 2025-01-17 | |
| Evaluation of Blowing Exercises Utilizing a Breathing Exercise Device in Otitis Media With Effusion Blowing exercise group - Otitis Media With Effusion (OME), Otitis Media With Effusion in Children | Not applicable | Completed | Uşak University | 51 | 2024-09-25 | 2026-05-05 |
| Distribution of Bacteria in OME After Radiotherapy For NPC. Otitis Media Effusion, Nasopharyngeal Carcinoma | Unknown | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 234 | 2024-05-12 | 2024-07-26 | |
| Microplastics in Otitis Media With Effusion Material ventilation tube insertion - Microplastics, Otitis Media With Effusion | Unknown | Kerem Kökoğlu | 40 | 2024-03-20 | 2024-03-27 | |
| Otitis Treatment With OtoSight™ - Modification of Antibiotic Treatment Intervention in Children OtoSight Middle Ear Scope - Otitis Media Acute | Active not recruiting | PhotoniCare, Inc. | 700 | 2024-01-10 | 2026-05-12 | |
| Hearing Improvement After Making a Hole Surgically in Eardrum With or Without Ventilation Tube in Children With Glue Ears Myringotomy with ventilation tube, Myringotomy alone - Otitis Media With Effusion in Children, Hearing Loss | Not applicable | Completed | Allama Iqbal Teaching Hospital | 60 | 2024-01-01 | 2025-04-03 |
| Evaluation of Outcomes Following In-office Tympanostomy Using the Tula® System: a Prospective, Multi-center Registry Iontophoresis and tube placement - Otitis Media With Effusion, Acute Otitis Media | Recruiting | Smith & Nephew, Inc. | 200 | 2023-06-15 | 2024-07-23 |
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Otitis Media (30) · Hearing Loss (8) · Hearing Loss, Conductive (6) · Tympanic Membrane Perforation (5) · Otitis (4) · Pneumococcal Infections (3) · Laryngopharyngeal Reflux (2) · Nasopharyngeal Carcinoma (2) · Behavior (1) · Charcot-Marie-Tooth disease, Type 1C (1) · Cholesteatoma (1) · Earache (1) · Food Hypersensitivity (1) · Gastroesophageal Reflux (1)
Ear Diseases (81) · Otorhinolaryngologic Diseases (81) · Otitis (77) · Otitis Media (51) · Pathological Conditions, Signs and Symptoms (14) · Nervous System Diseases (13) · Neurologic Manifestations (13) · Signs and Symptoms (13) · Hearing Disorders (12) · Sensation Disorders (12) · Infections (6) · Wounds and Injuries (6) · Hearing Loss (4) · Respiratory Tract Diseases (4) · Bacterial Infections (3)
Middle Ear Ventilation (9) · Adenoidectomy (6) · Acoustic Impedance Tests (2) · Iontophoresis (2) · Lansoprazole (2) · Mometasone Furoate (2) · salicylhydroxamic acid (2) · 23-valent pneumococcal capsular polysaccharide vaccine (1) · Acupuncture Therapy (1) · Adrenal Cortex Hormones (1) · Amoxicillin (1) · Amoxicillin-Potassium Clavulanate Combination (1) · Anti-Bacterial Agents (1) · Audiometry (1) · Blood Cell Count (1)
University Hospital Ostrava (3) · Vastra Gotaland Region (3) · Assiut University (2) · Eye & ENT Hospital of Fudan University (2) · Integra LifeSciences Corporation (2) · Menzies School of Health Research (2) · Otonomy, Inc. (2) · PhotoniCare, Inc. (2) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (2) · Tusker Medical (2) · University Hospital, Antwerp (2) · Aghia Sophia Children's Hospital of Athens (1) · Allama Iqbal Teaching Hospital (1) · Assistance Publique - Hôpitaux de Paris (1) · Bezmialem Vakif University (1)
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