11 completed, 6 unknown, 5 recruiting, 4 terminated. 7 Not applicable, 4 Phase 2, 4 Phase 3, 3 Phase 4.
Follow Endocarditis, Bacterial: new trials by email Literature Review of Endocarditis, Bacterial trials Research Report on Endocarditis, Bacterial
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dalbavancin Therapy for Infective Endocarditis Dalbavancin administration, Standard of Care (Investigator Choice) - Endocarditis Infective, Endocarditis, Bacterial | Phase 3 | Not yet recruiting | Stefan Hagel | 184 | 2026-12-01 | 2026-07-13 |
| AngioVac Aspiration Therapy Registry Retrospective analysis of assigned treatment - Intracardiac Thrombus, Intracardiac Mass | Not yet recruiting | Charite University, Berlin, Germany | 1000 | 2026-10-01 | 2026-10-20 | |
| Endocarditis Clinical Awareness, Research, and Evaluation in Sweden Endocarditis Infective, Endocarditis Acute and Subacute | Active not recruiting | Karolinska Institutet | 22000 | 2025-07-01 | 2026-06-30 | |
| Combined Rehabilitation and Nutritional Support vs. Standard Care in In-Hospital Endocarditis Treatment Intensive physical Therapy, Probiotic treatment, Individualised Nutritional Support - Infective Endocarditis, Endocarditis, Bacterial | Not applicable | Terminated | Johannes Grand | 15 | 2025-02-19 | 2025-12-15 |
| Bacteriophages in Addition to Antibiotics for the Treatment of Patients With Infective Endocarditis Bacteriophage - Endocarditis, Bacterial | Phase 3 | Recruiting | University Clinical Hospital na V.V.Vinogradov (branch of RUDN university na Patrice Lumumba) | 30 | 2025-02-05 | 2026-03-19 |
| New Treatment of Cardiac Device Infections; Immediate Reimplantation After Removal of Infected System Timing of reimplantation - Endocarditis, Bacterial | Phase 3 | Recruiting | Copenhagen University Hospital, Rigshospitalet | 176 | 2024-04-29 | 2026-10-01 |
| Plasma Pharmacological Monitoring of M Penicillins in Methicillin-sensitive Staphylococcus Aureus Bacteremia Staphylococcus Aureus Infection | Unknown | University Hospital, Strasbourg, France | 200 | 2023-07-19 | 2024-07-11 | |
| Effectiveness of Antibiotic Prophylaxis of Infective Endocarditis for Invasive Dental Procedures in Patients With Prosthetic Heart Valves and/or History of Infective Endocarditis Improved practices - Endocarditis, Bacterial, Endocarditis | Not applicable | Not yet recruiting | University Hospital, Bordeaux | 250000 | 2023-02-01 | 2023-02-02 |
| T2MR PCR Detection of ESKAPE Pathogens in Patients With Pyogenic Spondylodiscitis and Infective Endocarditis Osteomyelitis; Vertebra, Endocarditis, Bacterial | Unknown | Charles University, Czech Republic | 50 | 2022-09-01 | 2023-04-26 | |
| Predictors of Infective Endocarditis Among Patients Managed for Staphylococcus Aureus Bacteremia, Particularly Staphylococcus Aureus Bacteriuria, and Time to Blood Culture Positivity Bacteremia, Endocarditis, Bacterial | Unknown | Fondation Hôpital Saint-Joseph | 247 | 2022-07-18 | 2022-11-01 | |
| Characterization of Enterococcus Faecalis Endocarditis and Impact of Amoxicillin MIC Elevation on Patient Outcome Infectious Endocarditis | Completed | Fondation Hôpital Saint-Joseph | 281 | 2022-06-08 | 2023-09-13 | |
| Neurological Complication of Infective Endocarditis: A Prospective Multi-site Cohort Study Brain MRI, digital subtraction angiography (DSA) - Endocarditis, Bacterial, Aneurysm, Intracranial Mycotic | Unknown | the Jeunes en Neuroradiologie Interventionnelle (JENI) research group | 200 | 2022-01-01 | 2021-12-09 | |
| Anemia in Patients With Endocarditis Measurement of biomarkers for inflammation and anemia - Anemia, Endocarditis, Bacterial | Completed | Copenhagen University Hospital, Rigshospitalet | 209 | 2021-03-22 | 2025-09-26 | |
| Integrated Outpatient Treatment of Opioid Use Disorder and Severe Injection Related Infections Buprenorphine and Outpatient Parenteral Antibiotic Therapy, Buprenorphine and standard of care antibiotic treatment - Drug Use, Opioid-use Disorder | Phase 2 | Completed | Laura Fanucchi | 71 | 2021-03-16 | 2026-04-28 |
| Short-course Antibiotic Treatment in Gram-positive Cocci Infective Endocarditis Antibiotics - Endocarditis, Bacterial | Phase 4 | Terminated | Carmen Olmos Blanco | 20 | 2021-01-26 | 2023-09-28 |
| Impact of Preoperative Dental Screening in Reducing Infective Endocarditis Risk in Transcatheter Aortic Valve Implantation Patients No preoperative dental screening - Transcatheter Aortic Valve Implantation, Dental | Recruiting | Odense University Hospital | 1000 | 2020-01-01 | 2026-10-21 | |
| Hyperbaric Oxygen Treatment in Humans With Gram Positive Cocci Endocarditis Hyperbaric oxygen - Infectious Endocarditis | Phase 2 | Unknown | Ole Hyldegaard | 10 | 2019-12-01 | 2020-12-31 |
| Barts Endocarditis Research Registry registry - Infective Endocarditis, Endocarditis | Recruiting | Queen Mary University of London | 1000 | 2019-04-24 | 2026-07-17 | |
| Accelerated Treatment of Endocarditis Accelerated treatment of endocarditis, Usual guideline therapy - Infectious Endocarditis | Not applicable | Active not recruiting | Copenhagen University Hospital, Rigshospitalet | 508 | 2019-01-17 | 2026-07-23 |
| Contribution of 18F-FDG PET-CT in the Diagnosis and the Detection of Peripheral Emboli of Infectious Endocarditis on Native Valves Whole-body 18F-FDG PET-CT scan - Endocarditis | Not applicable | Completed | University Hospital, Bordeaux | 31 | 2018-11-10 | 2026-06-01 |
Showing 20 of 31. Sign in to see all of them.
Endocarditis (16) · Endocarditis, Subacute Bacterial (10) · Bacteremia (5) · Gram-Positive Bacterial Infections (3) · Staphylococcal Infections (3) · Infections (2) · Opioid-Related Disorders (2) · Osteomyelitis (2) · Anemia (1) · Bacterial Infections (1) · Bone Diseases, Infectious (1) · Brain Abscess (1) · Brain Injuries (1) · Central Nervous System Bacterial Infections (1)
Bacterial Infections and Mycoses (31) · Cardiovascular Diseases (31) · Cardiovascular Infections (31) · Heart Diseases (31) · Bacterial Infections (30) · Infections (29) · Endocarditis (15) · Gram-Positive Bacterial Infections (10) · Streptococcal Infections (10) · Inflammation (5) · Pathologic Processes (5) · Pathological Conditions, Signs and Symptoms (5) · Systemic Inflammatory Response Syndrome (5) · Sepsis (4)
Daptomycin (3) · Angiography, Digital Subtraction (1) · Anti-Bacterial Agents (1) · Buprenorphine (1) · Buprenorphine, Naloxone Drug Combination (1) · Ceftriaxone (1) · Hyperbaric Oxygenation (1) · Injections (1) · Magnetic Resonance Spectroscopy (1) · Registries (1) · Standard of Care (1) · Sublocade (1) · Vancomycin (1)
Copenhagen University Hospital, Rigshospitalet (3) · Fondation Hôpital Saint-Joseph (3) · Assistance Publique - Hôpitaux de Paris (2) · Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (2) · Laura Fanucchi (2) · University Hospital, Bordeaux (2) · Carmen Olmos Blanco (1) · Charite University, Berlin, Germany (1) · Charles University, Czech Republic (1) · Fundación Pública Andaluza para la gestión de la Investigación en Sevilla (1) · Hospices Civils de Lyon (1) · Infectopharm Arzneimittel GmbH (1) · Johannes Grand (1) · Karolinska Institutet (1) · Odense University Hospital (1)
France (8) · Denmark (7) · United States (5) · Germany (3) · Spain (2) · Sweden (2) · United Kingdom (2) · Austria (1) · Czechia (1) · Greece (1) · Italy (1) · Russia (1)
Christoph Starck, Prof. Dr. med. (1) · Henning Bundgaard, MD (1) · Henning Henning (1) · Jane B Knudsen, Dr. (1) · Johannes Grand, MD, PhD (1) · Jordi S Dahl, MD,PhD,DMSc (1) · Klaus-Friedrich Bodmann, Dr. (1) · Kyu Y Rhee, MD, PhD (1) · Laura Fanucchi, MD (1) · Ole Hyldegaard, MD, PHD (1)
PMID 24003046, PMID 16914701, PMID 18491965, PMID 20404380, PMID 20462352, PMID 22334638, PMID 23648777, PMID 24497495, PMID 26320109, PMID 26373316, PMID 28848178, PMID 30519794, PMID 31342057, PMID 31533190, PMID 32546269, PMID 36797077, PMID 40106180, PMID 40716613, PMID 42286374, PMID 42663314
2019 (1), R01DA048892 (1)