16 completed, 6 unknown, 5 recruiting, 4 not yet recruiting. 10 Not applicable, 6 Phase 3, 5 Phase 2, 3 Phase 4.
Follow Cardiovascular Infections: new trials by email Literature Review of Cardiovascular Infections trials Research Report on Cardiovascular Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dalbavancin Therapy for Infective Endocarditis Dalbavancin administration, Standard of Care (Investigator Choice) - Endocarditis Infective, Endocarditis, Bacterial | Phase 3 | Not yet recruiting | Stefan Hagel | 184 | 2026-12-01 | 2026-07-13 |
| A Study of Ceftobiprole Compared With Standard Antibiotic Treatment in Children With Staphylococcus Aureus Bacteremia (SAB) Infection, Including Right-sided Heart Infection Ceftobiprole medocaril sodium, Standard of Care (SOC) - Staphylococcus Aureus Bacteremia, Endocarditis, Bacterial | Phase 3 | Not yet recruiting | ISTx, LLC | 60 | 2026-10-30 | 2026-11-10 |
| AngioVac Aspiration Therapy Registry Retrospective analysis of assigned treatment - Intracardiac Thrombus, Intracardiac Mass | Not yet recruiting | Charite University, Berlin, Germany | 1000 | 2026-10-01 | 2026-10-20 | |
| Endocarditis Clinical Awareness, Research, and Evaluation in Sweden Endocarditis Infective, Endocarditis Acute and Subacute | Active not recruiting | Karolinska Institutet | 22000 | 2025-07-01 | 2026-06-30 | |
| Combined Rehabilitation and Nutritional Support vs. Standard Care in In-Hospital Endocarditis Treatment Intensive physical Therapy, Probiotic treatment, Individualised Nutritional Support - Infective Endocarditis, Endocarditis, Bacterial | Not applicable | Terminated | Johannes Grand | 15 | 2025-02-19 | 2025-12-15 |
| Bacteriophages in Addition to Antibiotics for the Treatment of Patients With Infective Endocarditis Bacteriophage - Endocarditis, Bacterial | Phase 3 | Recruiting | University Clinical Hospital na V.V.Vinogradov (branch of RUDN university na Patrice Lumumba) | 30 | 2025-02-05 | 2026-03-19 |
| New Treatment of Cardiac Device Infections; Immediate Reimplantation After Removal of Infected System Timing of reimplantation - Endocarditis, Bacterial | Phase 3 | Recruiting | Copenhagen University Hospital, Rigshospitalet | 176 | 2024-04-29 | 2026-10-01 |
| Plasma Pharmacological Monitoring of M Penicillins in Methicillin-sensitive Staphylococcus Aureus Bacteremia Staphylococcus Aureus Infection | Unknown | University Hospital, Strasbourg, France | 200 | 2023-07-19 | 2024-07-11 | |
| Effectiveness of Antibiotic Prophylaxis of Infective Endocarditis for Invasive Dental Procedures in Patients With Prosthetic Heart Valves and/or History of Infective Endocarditis Improved practices - Endocarditis, Bacterial, Endocarditis | Not applicable | Not yet recruiting | University Hospital, Bordeaux | 250000 | 2023-02-01 | 2023-02-02 |
| T2MR PCR Detection of ESKAPE Pathogens in Patients With Pyogenic Spondylodiscitis and Infective Endocarditis Osteomyelitis; Vertebra, Endocarditis, Bacterial | Unknown | Charles University, Czech Republic | 50 | 2022-09-01 | 2023-04-26 | |
| Predictors of Infective Endocarditis Among Patients Managed for Staphylococcus Aureus Bacteremia, Particularly Staphylococcus Aureus Bacteriuria, and Time to Blood Culture Positivity Bacteremia, Endocarditis, Bacterial | Unknown | Fondation Hôpital Saint-Joseph | 247 | 2022-07-18 | 2022-11-01 | |
| Characterization of Enterococcus Faecalis Endocarditis and Impact of Amoxicillin MIC Elevation on Patient Outcome Infectious Endocarditis | Completed | Fondation Hôpital Saint-Joseph | 281 | 2022-06-08 | 2023-09-13 | |
| High vs. Standard Dose Rifampicin for Effusive Tuberculous Pericarditis high dose Rifampicin (RIF) - Tuberculous Pericarditis, HIV Status | Phase 2 | Completed | University of Cape Town | 52 | 2022-01-10 | 2026-09-01 |
| Neurological Complication of Infective Endocarditis: A Prospective Multi-site Cohort Study Brain MRI, digital subtraction angiography (DSA) - Endocarditis, Bacterial, Aneurysm, Intracranial Mycotic | Unknown | the Jeunes en Neuroradiologie Interventionnelle (JENI) research group | 200 | 2022-01-01 | 2021-12-09 | |
| Anemia in Patients With Endocarditis Measurement of biomarkers for inflammation and anemia - Anemia, Endocarditis, Bacterial | Completed | Copenhagen University Hospital, Rigshospitalet | 209 | 2021-03-22 | 2025-09-26 | |
| Integrated Outpatient Treatment of Opioid Use Disorder and Severe Injection Related Infections Buprenorphine and Outpatient Parenteral Antibiotic Therapy, Buprenorphine and standard of care antibiotic treatment - Drug Use, Opioid-use Disorder | Phase 2 | Completed | Laura Fanucchi | 71 | 2021-03-16 | 2026-04-28 |
| Short-course Antibiotic Treatment in Gram-positive Cocci Infective Endocarditis Antibiotics - Endocarditis, Bacterial | Phase 4 | Terminated | Carmen Olmos Blanco | 20 | 2021-01-26 | 2023-09-28 |
| Impact of Preoperative Dental Screening in Reducing Infective Endocarditis Risk in Transcatheter Aortic Valve Implantation Patients No preoperative dental screening - Transcatheter Aortic Valve Implantation, Dental | Recruiting | Odense University Hospital | 1000 | 2020-01-01 | 2026-10-21 | |
| Hyperbaric Oxygen Treatment in Humans With Gram Positive Cocci Endocarditis Hyperbaric oxygen - Infectious Endocarditis | Phase 2 | Unknown | Ole Hyldegaard | 10 | 2019-12-01 | 2020-12-31 |
| Barts Endocarditis Research Registry registry - Infective Endocarditis, Endocarditis | Recruiting | Queen Mary University of London | 1000 | 2019-04-24 | 2026-07-17 |
Showing 20 of 37. Sign in to see all of them.
Endocarditis, Bacterial (22) · Endocarditis (16) · Endocarditis, Subacute Bacterial (10) · Bacteremia (5) · Gram-Positive Bacterial Infections (3) · Infections (3) · Staphylococcal Infections (3) · Opioid-Related Disorders (2) · Osteomyelitis (2) · Pericarditis, Tuberculous (2) · Anemia (1) · Bacterial Infections (1) · Bone Diseases, Infectious (1) · Brain Abscess (1)
Cardiovascular Diseases (37) · Heart Diseases (35) · Bacterial Infections and Mycoses (34) · Infections (34) · Bacterial Infections (33) · Endocarditis (16) · Gram-Positive Bacterial Infections (12) · Endocarditis, Bacterial (10) · Streptococcal Infections (10) · Inflammation (5) · Pathologic Processes (5) · Pathological Conditions, Signs and Symptoms (5) · Systemic Inflammatory Response Syndrome (5) · Sepsis (4)
Daptomycin (3) · Standard of Care (2) · Angiography, Digital Subtraction (1) · Anti-Bacterial Agents (1) · Buprenorphine (1) · Buprenorphine, Naloxone Drug Combination (1) · Ceftriaxone (1) · Hyperbaric Oxygenation (1) · Immuvac (1) · Injections (1) · Magnetic Resonance Spectroscopy (1) · Methylprednisolone (1) · Prednisolone (1) · Registries (1) · Rifampin (1)
Copenhagen University Hospital, Rigshospitalet (3) · Fondation Hôpital Saint-Joseph (3) · Assistance Publique - Hôpitaux de Paris (2) · Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (2) · Laura Fanucchi (2) · University Hospital, Bordeaux (2) · University of Cape Town (2) · Carmen Olmos Blanco (1) · Charite University, Berlin, Germany (1) · Charles University, Czech Republic (1) · Emilia Nozawa, PT PhD (1) · Federal University of São Paulo (1) · Fundación Pública Andaluza para la gestión de la Investigación en Sevilla (1) · Hospices Civils de Lyon (1) · ISTx, LLC (1)
France (8) · Denmark (7) · United States (6) · Germany (3) · South Africa (2) · Spain (2) · Sweden (2) · United Kingdom (2) · Austria (1) · Brazil (1) · Czechia (1) · Greece (1) · Italy (1) · Russia (1)
Christoph Starck, Prof. Dr. med. (1) · Cristiane D Goncalves, FT (1) · Filomena G Gallas, PHD (1) · Henning Bundgaard, MD (1) · Henning Henning (1) · Jane B Knudsen, Dr. (1) · Johannes Grand, MD, PhD (1) · Jordi S Dahl, MD,PhD,DMSc (1) · Klaus-Friedrich Bodmann, Dr. (1) · Kyu Y Rhee, MD, PhD (1)
PMID 24003046, PMID 13129420, PMID 16055882, PMID 16305872, PMID 16914701, PMID 17768574, PMID 17934967, PMID 18047460, PMID 18491965, PMID 18760163, PMID 19272785, PMID 19303579, PMID 20404380, PMID 20462352, PMID 20625667, PMID 21529357, PMID 22334638, PMID 23648777, PMID 24497495, PMID 25178809, PMID 26320109, PMID 26373316, PMID 28848178, PMID 30519794, PMID 31342057, PMID 31533190, PMID 32546269, PMID 36797077, PMID 40106180, PMID 40716613, PMID 42286374, PMID 42663314
2019 (1), R01DA048892 (1)