71 completed, 14 terminated, 14 unknown, 3 recruiting. 107 Phase 2, 22 Phase 1, 16 Phase 3.
Follow End Stage Renal Disease: new trials by email Literature Review of End Stage Renal Disease trials Research Report on End Stage Renal Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Bupropion for Fatigue in End-stage Kidney Disease Patients on Hemodialysis Bupropion Hydrochloride 150 MG - End Stage Renal Disease, Fatigue | Phase 1 / Phase 2 | Not yet recruiting | The University of Texas Health Science Center at San Antonio | 16 | 2027-02-01 | 2026-11-02 |
| Development of an Innovative Hemodialysis Method to Improve Dialytic Clearance of Protein-bound Uremic Toxins Medialipide 20% perfusion, NaCl 0,9%, Blood sample - End Stage Renal Disease, Chronic Hemolysis | Phase 2 | Not yet recruiting | Hospices Civils de Lyon | 12 | 2025-01-01 | 2024-09-19 |
| Study the Effect of Probiotic Supplementation on Trimethylamine-N-Oxide Plasma Level in Hemodialysis Patients Lactobacillus containing probiotic - End Stage Renal Disease | Phase 2 / Phase 3 | Unknown | Al-Azhar University | 80 | 2024-03-15 | 2024-05-20 |
| Safety and Efficacy of Empagliflozin in Hemodialysis Empagliflozin 10 MG, Placebo - End Stage Renal Disease | Phase 2 | Recruiting | NYU Langone Health | 60 | 2024-01-31 | 2025-12-04 |
| Impact of Black Seed Oil on Hemodialysis Patients Black Seed Oil, Placebo - End Stage Renal Disease | Phase 2 | Unknown | Ain Shams University | 60 | 2023-02-22 | 2023-04-21 |
| Initial Safety Study of the TRUE AVC in Hemodialysis Access (TRUE AVC I Study) Arteriovenous conduit implant - End Stage Renal Disease | Phase 1 / Phase 2 | Completed | Vascudyne, Inc. | 11 | 2022-10-04 | 2025-07-03 |
| Reduction of Peritoneal Glucose Uptake With Use of SGLT2 in Humans Undergoing Peritoneal Dialysis Treatment Dapagliflozin 10 MG [Farxiga] - End Stage Renal Disease, Peritoneal Dialysis Complication | Phase 2 | Unknown | Holbaek Sygehus | 10 | 2021-11-18 | 2022-02-22 |
| A Trial of Transplanting Hepatitis C Kidneys Into Hepatitis C-Negative Kidney Recipients Epclusa - End Stage Renal Disease | Phase 2 | Completed | University of Pennsylvania | 201 | 2021-06-22 | 2026-03-12 |
| Dapagliflozin Effect on Cardiovascular Outcomes in Haemodialysis for End Stage Renal Disease Dapagliflozin, Placebo - Cardiovascular Diseases, End Stage Renal Disease | Phase 2 / Phase 3 | Withdrawn | Tan Tock Seng Hospital | 2021-06-01 | 2021-10-21 | |
| Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD DCR-PHXC - Primary Hyperoxaluria Type 1, End Stage Renal Disease | Phase 2 | Recruiting | Dicerna Pharmaceuticals, Inc., a Novo Nordisk company | 28 | 2021-04-15 | 2025-12-24 |
| Safety & Tolerability Study of Chimeric Antigen Receptor T-Reg Cell Therapy in Living Donor Renal Transplant Recipients TX200-TR101 - Kidney Transplant Rejection, End Stage Renal Disease | Phase 1 / Phase 2 | Completed | Sangamo Therapeutics | 26 | 2021-03-17 | 2026-07-02 |
| Berinert (C1INH) vs Placebo for DGF/IRI Berinert, Placebo - End Stage Renal Disease, Chronic Kidney Diseases | Phase 1 / Phase 2 | Completed | Cedars-Sinai Medical Center | 45 | 2021-03-03 | 2024-12-04 |
| Efficacy of Diuretics in Kidney Disease Metolazone, Placebo - Chronic Kidney Disease, End Stage Renal Disease | Phase 2 | Terminated | Stanford University | 17 | 2021-03-01 | 2025-06-05 |
| HOPE Consortium Trial to Reduce Pain and Opioid Use in Hemodialysis Pain Coping Skills Training (PCST), Buprenorphine - End Stage Renal Disease, Chronic Pain | Phase 2 | Completed | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 643 | 2021-01-03 | 2025-01-13 |
| Study to Investigate the Pharmacokinetic Comparability of Dosing Triferic AVNU IV by Continuous Infusion and IV Bolus. Triferic - End Stage Renal Disease | Phase 1 / Phase 2 | Completed | Rockwell Medical Technologies, Inc. | 23 | 2020-06-25 | 2021-07-13 |
| AZD1656 in Transplantation With Diabetes tO PromoTe Immune TOleraNce AZD1656, Placebo - Type 2 Diabetes, Diabetes Mellitus, Type 2 | Phase 2 | Completed | Queen Mary University of London | 26 | 2019-12-13 | 2024-06-20 |
| Safety and Efficacy Assessment of HAV in Patients Needing Vascular Access for Dialysis HAV - Renal Failure, End Stage Renal Disease | Phase 2 | Completed | Humacyte, Inc. | 30 | 2019-11-12 | 2024-03-19 |
| A Study to Investigate the Effect of Triferic Plus Heparin Infusion Compared to Heparin Alone on Coagulation Parameters in Hemodialysis Patients Triferic, Heparin - End Stage Renal Disease | Phase 1 / Phase 2 | Completed | Rockwell Medical Technologies, Inc. | 12 | 2019-09-30 | 2020-12-02 |
| Effect of Vitamin K 2 on Vascular Calcification in Hemodialysis Patients Vitamin K2, Cholecalciferol (inactive vitamin D), Vitamin K2 and Cholecalciferol - End Stage Renal Disease | Phase 2 / Phase 3 | Unknown | Ain Shams University | 60 | 2019-09-01 | 2019-10-30 |
| Efficacy and Safety Assessments of a Peritoneal Dialysis Solution Containing Glucose, Xylitol, and L-Carnitine in CAPD 1.5% Xylitol, 0.5% Glucose, and 0.02% L-carnitine, 0.7% Xylitol, 0.5% Glucose, and 0.02% L-carnitine - End Stage Renal Disease | Phase 2 | Terminated | Iperboreal Pharma Srl | 11 | 2019-09-01 | 2023-03-03 |
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Kidney Failure, Chronic (107) · Renal Insufficiency, Chronic (14) · Anemia (7) · Renal Insufficiency (6) · Inflammation (4) · Kidney Diseases (4) · Dyslipidemias (3) · Insulin Resistance (3) · Malnutrition (3) · Cardiovascular Diseases (2) · Diabetes Mellitus (2) · Hyperparathyroidism, Secondary (2) · Hypotension (2) · Restless Legs Syndrome (2) · Sleep Wake Disorders (2)
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Exercise (5) · spleen fibrinolytic proteinase (human) (5) · Cinacalcet (4) · Dietary Supplements (4) · ferric pyrophosphate (4) · Rituximab (3) · Saline Solution (3) · Sodium Chloride (3) · Calcitriol (2) · Carnitine (2) · Cholecalciferol (2) · Complement C1 Inhibitor Protein (2) · Epoetin Alfa (2) · Growth Hormone (2) · Immunoglobulins, Intravenous (2)
Vanderbilt University (9) · Rockwell Medical Technologies, Inc. (5) · Ain Shams University (4) · Amgen (4) · Iperboreal Pharma Srl (3) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (3) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (3) · Aronora, Inc. (2) · Cedars-Sinai Medical Center (2) · Columbia University (2) · Kyntra Bio (2) · Massachusetts General Hospital (2) · NYU Langone Health (2) · Shiraz University of Medical Sciences (2) · University of Pennsylvania (2)
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Alp Ikizler, MD (9) · Alan S. Kliger, M.D. (2) · Arduino Arduini, MD (2) · Gerald J. Beck, Ph.D. (2) · Kieran McCafferty, M.B., B.Chir (2) · Mario Bonomini, MD (2) · Paul W. Eggers, Ph.D. (2) · A. Benedict Cosimi, M.D. (1) · Agostino Naso, MD (1) · Ain Shams (1) · Akinlolu Ojo, MD (1) · Alfredo R Zarate, MD (1) · Andrew A House, MD (1) · Anjali Ganda, M.D., M.S. (1)
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