10 recruiting, 9 completed, 6 unknown, 4 withdrawn. 16 Not applicable, 4 Phase 2, 1 Early Phase 1, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 16 | Recruiting 5, Completed 4, Withdrawn 3, Active not recruiting 2, Unknown 2 |
| Phase 2 | 4 | Completed 3, Recruiting 1 |
| Early Phase 1 | 1 | Unknown 1 |
| Phase 1 | 1 | Recruiting 1 |
Follow Emphysema or COPD: new trials by email Literature Review of Emphysema or COPD trials Research Report on Emphysema or COPD
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Improve Muscle Weakness in Patient With COPD Aerobic Exercise Combined with Blood Flow Restriction, Aerobic exercise - Emphysema or COPD | Not applicable | Withdrawn | Al-Zaytoonah University of Jordan | 2026-06-10 | 2026-10-21 | |
| A Multi Center Study Testing a New Implant for Adults With Severe Emphysema Implantable Artificial Bronchus - Emphysema or COPD, Emphysema | Not applicable | Recruiting | Pulmair Medical, Inc. | 60 | 2026-03-25 | 2026-10-14 |
| Utilising Hull Lung Health Study Data to Investigate the Performance of TidalSense Diagnostic Algorithms to Identify COPD and Pre-COPD Among Participants in the FRONTIER Programme. COPD, Emphysema or COPD | Not yet recruiting | Chiesi UK | 1200 | 2025-08-01 | 2025-05-31 | |
| PiMZ Longitudinal Cohort (PiMZ Logic) Alpha 1-Antitrypsin Deficiency, Emphysema or COPD | Recruiting | Columbia University | 80 | 2025-05-30 | 2026-01-16 | |
| The REDUCE EU Study - Endobronchial Thermal Liquid Ablation (ETLA) for the Treatment of Emphysema Endobronchial Therman Liquid Ablation (ETLA) - Emphysema or COPD, Emphysema | Not applicable | Recruiting | Morair Medtech, LLC | 30 | 2025-01-10 | 2025-01-28 |
| Maximizing Benefit of Lung Cancer Screening Incidental Findings of Cardiovascular, Respiratory and Breast Measures System implementation of patient-centered incidental findings report - Coronary Disease, Emphysema or COPD | Not applicable | Withdrawn | University of Montana | 2024-12-01 | 2024-12-09 | |
| Anti-Platelets in Chronic Obstructive Pulmonary Disease dual anti-platelet therapy, Placebo - COPD, Emphysema | Phase 2 | Completed | Brigham and Women's Hospital | 15 | 2024-03-27 | 2026-05-14 |
| An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema AeriSeal System - Emphysema, Pulmonary, Emphysema or COPD | Not applicable | Recruiting | Pulmonx Corporation | 200 | 2024-02-22 | 2026-09-17 |
| Airway Bypass - Safety and Feasibility Study Airway Bypass - Emphysema or COPD | Early Phase 1 | Unknown | Zoar Engelman | 10 | 2024-01-26 | 2024-02-08 |
| The Effect of Treatment of Emphysema With Endobronchial Valves on the Diaphragm Mobility Chronic Obstructive Pulmonary Disease, Emphysema or COPD | Recruiting | Aarhus University Hospital | 35 | 2023-11-27 | 2023-12-08 | |
| RCT of Vapendavir in Patients With COPD and Human Rhinovirus/Enterovirus Upper Respiratory Infection Vapendavir, Placebo - COPD Exacerbation Acute, COPD With Acute Lower Respiratory Infection | Phase 2 | Completed | Altesa Biosciences, Inc. | 52 | 2023-11-20 | 2025-09-30 |
| Telehealth and Onsite Maintenance Exercise in Chronic Lung Disease Onsite Maintenance Exercise Training, Telehealth Maintenance Exercise - Copd, COPD Exacerbation | Not applicable | Unknown | MGH Institute of Health Professions | 30 | 2023-09-01 | 2024-08-01 |
| Study to Assess Safety, Feasibility, and Preliminary Efficacy of the Apreo Implant for Severe Emphysema Apreo Implant Group - Emphysema or COPD | Not applicable | Active not recruiting | Apreo Health, Inc. | 30 | 2023-08-15 | 2026-03-31 |
| First in Human Study to Assess an Implant to Treat Severe Emphysema Apreo Implant Group - Emphysema or COPD | Not applicable | Completed | Apreo Health, Inc. | 48 | 2023-05-05 | 2026-03-31 |
| Ultrasound and Respiratory Physiological Signals in Lung Diseases Lung ultrasound, computed tomographic scan and patch-based cardio-respiratory evaluations - Interstitial Lung Disease, Interstitial Lung Diseases | Not applicable | Recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 25 | 2023-03-22 | 2026-05-20 |
| Healthy At Home Pilot COPD, COPD Exacerbation | Completed | University of Massachusetts, Worcester | 100 | 2022-09-09 | 2024-10-16 | |
| Inter-lobar Fissure Completion in Patients With Failed Bronchoscopic Lung Volume Reduction Interlobar fissure completion and pleural adhesiolysis - Emphysema or COPD | Not applicable | Recruiting | Beth Israel Deaconess Medical Center | 20 | 2022-05-24 | 2026-08-28 |
| Introduction of the Vapor Treatment in The Netherlands NA: intervention is not part of the study - Emphysema or COPD | Withdrawn | University Medical Center Groningen | 2021-12-01 | 2022-03-14 | ||
| Combined Zephyr Valve System With Inter-lobar Fissure Completion for Lung Volume Reduction in Emphysema Robotic or VATS lobar fissure completion, Endobronchial valves placement - Emphysema or COPD | Not applicable | Active not recruiting | Beth Israel Deaconess Medical Center | 20 | 2021-08-01 | 2026-11-12 |
| Evaluation of the Free Flow Medical Lung Tensioning Device System for the Treatment of Severe Emphysema FreeFlowMedical Lung Tensioning Device - Emphysema or COPD | Not applicable | Completed | University Medical Center Groningen | 14 | 2021-06-23 | 2023-11-21 |
Showing 20 of 32. Sign in to see all of them.
Emphysema (32) · Pulmonary Disease, Chronic Obstructive (32) · alpha 1-Antitrypsin Deficiency (3) · Lung Diseases, Interstitial (2) · Lung Diseases, Obstructive (2) · Pulmonary Emphysema (2) · Pulmonary Fibrosis (2) · Respiratory Tract Diseases (2) · Aneurysm (1) · Bronchiectasis (1) · Bronchitis, Chronic (1) · Common Cold (1) · Coronary Disease (1) · Cystic Fibrosis (1) · Enterovirus Infections (1)
Chronic Disease (32) · Disease Attributes (32) · Pathologic Processes (32) · Pathological Conditions, Signs and Symptoms (32) · Lung Diseases (31) · Lung Diseases, Obstructive (30) · Respiratory Tract Diseases (30) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Digestive System Diseases (3) · Genetic Diseases, Inborn (3) · Liver Diseases (3) · Subcutaneous Emphysema (3) · Bronchial Diseases (2) · Cardiovascular Diseases (2) · Fibrosis (2)
Pneumonectomy (2) · Alemtuzumab (1) · Aspirin (1) · Blood Specimen Collection (1) · Clopidogrel (1) · Defecation (1) · Dual Anti-Platelet Therapy (1) · Exercise (1) · Filgrastim (1) · Granulocyte Colony-Stimulating Factor (1) · Histocompatibility Testing (1) · Hydroxyurea (1) · Methylprednisolone (1) · Phlebotomy (1) · Rituximab (1)
University Medical Center Groningen (4) · Apreo Health, Inc. (2) · Beth Israel Deaconess Medical Center (2) · Pulmonx Corporation (2) · Uptake Medical Technology, Inc. (2) · Aarhus University Hospital (1) · Al-Zaytoonah University of Jordan (1) · Altesa Biosciences, Inc. (1) · Asan Medical Center (1) · Brigham and Women's Hospital (1) · Canisius-Wilhelmina Hospital (1) · Chiesi UK (1) · Columbia University (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Lung Institute (1)
United States (12) · Netherlands (7) · Germany (6) · Austria (4) · United Kingdom (3) · Australia (2) · Denmark (2) · France (2) · Italy (2) · Georgia (1) · South Korea (1) · Spain (1) · Switzerland (1)
Dirk-Jan Slebos, MD PhD (3) · Adnan Majid, MD (1) · Andrea Smargiassi, MD, PhD (1) · Apurv Soni, MD, PhD (1) · Carrie L Pistenmaa, MD, MS (1) · Clemens Aigner, Prof. MD (1) · Dennis McHugh (1) · Felix Herth (1) · Felix Herth, MD, PhD (1) · Karen Watkins (1) · Mark T Dransfield, MD (1) · Micheal Crooks, Prof (1) · Monica Goldklang, MD (1) · Narinder Shargill, PhD (1) · Onn Min Kon, MD (1)
PMID 40387356, PMID 31421111, PMID 33590989, PMID 37495367, PMID 38746125, PMID 39468649, PMID 40854211
4UH3TR002450-02 (1), K23HL141651 (1)