3 completed, 1 recruiting. 4 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 3, Recruiting 1 |
| Phase 1 | 1 | Recruiting 1 |
Follow Emphysema or COPD: new trials by email Literature Review of Emphysema or COPD trials Research Report on Emphysema or COPD
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Anti-Platelets in Chronic Obstructive Pulmonary Disease dual anti-platelet therapy, Placebo - COPD, Emphysema | Phase 2 | Completed | Brigham and Women's Hospital | 15 | 2024-03-27 | 2026-05-14 |
| RCT of Vapendavir in Patients With COPD and Human Rhinovirus/Enterovirus Upper Respiratory Infection Vapendavir, Placebo - COPD Exacerbation Acute, COPD With Acute Lower Respiratory Infection | Phase 2 | Completed | Altesa Biosciences, Inc. | 52 | 2023-11-20 | 2025-09-30 |
| Alvelestat (MPH966) for the Treatment of ALpha-1 ANTitrypsin Deficiency Alvelestat (MPH966), Placebo - Alpha-1 Antitrypsin Deficiency (AATD), Pi*ZZ, Pi*SZ, Pi*Null, Another Rare Phenotype/Genotype Known to be Associated With Either Low or Functionally Impaired AAT Including F or I Mutations | Phase 2 | Completed | University of Alabama at Birmingham | 63 | 2019-04-08 | 2024-08-20 |
| Lung and Bone Marrow Transplantation for Lung and Bone Marrow Failure CD3/CD19 negative hematopoietic stem cells, Rituximab, Alemtuzumab - Idiopathic Pulmonary Fibrosis, Emphysema or COPD | Phase 1 / Phase 2 | Recruiting | Paul Szabolcs | 8 | 2018-04-19 | 2026-01-13 |
Emphysema (4) · Pulmonary Disease, Chronic Obstructive (4) · Common Cold (1) · Enterovirus Infections (1) · Idiopathic Pulmonary Fibrosis (1) · Infections (1) · Lung Diseases (1) · Lung Diseases, Obstructive (1) · Pulmonary Fibrosis (1) · RNA Virus Infections (1) · Respiration Disorders (1) · Respiratory Tract Diseases (1) · Respiratory Tract Infections (1) · Virus Diseases (1) · alpha 1-Antitrypsin Deficiency (1)
Chronic Disease (4) · Disease Attributes (4) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Lung Diseases (3) · Lung Diseases, Obstructive (3) · Respiratory Tract Diseases (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Digestive System Diseases (1) · Fibrosis (1) · Genetic Diseases, Inborn (1) · Liver Diseases (1) · Lung Diseases, Interstitial (1) · Picornaviridae Infections (1) · Subcutaneous Emphysema (1)
Alemtuzumab (1) · Aspirin (1) · Clopidogrel (1) · Dual Anti-Platelet Therapy (1) · Filgrastim (1) · Granulocyte Colony-Stimulating Factor (1) · Hydroxyurea (1) · Rituximab (1) · Thiotepa (1) · fludarabine (1) · fludarabine phosphate (1)
Altesa Biosciences, Inc. (1) · Brigham and Women's Hospital (1) · Paul Szabolcs (1) · University of Alabama at Birmingham (1)
United States (3) · United Kingdom (1)
Carrie L Pistenmaa, MD, MS (1) · Mark T Dransfield, MD (1) · Onn Min Kon, MD (1)
4UH3TR002450-02 (1), K23HL141651 (1)