11 completed. 11 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 11 | Completed 11 |
| Phase 2 | 4 | Completed 4 |
Follow Dystonia: new trials by email Literature Review of Dystonia trials Research Report on Dystonia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Single and Multiple Ascending Dose Study of MTR-601 in Healthy Individuals MTR-601 - Muscle Spasticity, Hypertonia, Muscle | Phase 1 | Completed | Motric Bio | 89 | 2023-09-11 | 2026-06-05 |
| Clinical Trial to Compare the Safety and Efficacy of Botulax® Versus Botox® in Patients With Cervical Dystonia Botulinum toxin type A injection, Botulinum Toxin Type A Injection [Botox] - Cervical Dystonia | Phase 1 | Completed | Hugel | 38 | 2020-05-26 | 2022-04-22 |
| Safety and Tolerability of Perampanel in Cervical Dystonia Perampanel - Cervical Dystonia | Phase 1 / Phase 2 | Completed | University Health Network, Toronto | 25 | 2017-09-01 | 2020-04-07 |
| Pilot Trial of Botulinum Toxin and Occupational Therapy for Writer's Cramp BoNT Injections, Occupational Therapy - Dystonia | Phase 1 / Phase 2 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 13 | 2013-12-03 | 2018-03-20 |
| Magnetic Resonance (MR) Guided Functional Ultrasound-Neurosurgery for Movement Disorders Non-invasive intervention with focused ultrasound (ExAblate 4000) - Essential Tremor, Dystonia | Phase 1 | Completed | University Children's Hospital, Zurich | 10 | 2012-11-01 | 2014-10-09 |
| Ampicillin for DYT-1 Dystonia Motor Symptoms Ampicillin, Sugar pill - DYT-1, Dystonia | Phase 1 | Completed | University of Florida | 2 | 2011-09-01 | 2017-07-05 |
| A Study of Acetyl Hexapeptide-8 (AH8) in Treatment of Blepharospasm Acetyl-Hexapeptide Topical Treatment, placebo - Focal Dystonia | Phase 1 / Phase 2 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 24 | 2009-07-01 | 2012-09-06 |
| PurTox (Botulinum Toxin Type A) for the Treatment of Adult Onset Spasmodic Torticollis/Cervical Dystonia Mentor Purified Toxin, Botulinum Toxn Type A, Purified Neurotoxin, Physiologic saline - Spasmodic Torticollis | Phase 1 | Completed | Mentor Worldwide, LLC | 70 | 2006-05-01 | 2016-03-29 |
| Deep Brain Stimulation to Treat Cervical Dystonia Electrodes - Cervical Dystonia | Phase 1 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 40 | 2005-08-01 | 2006-07-06 |
| Botulinum Toxin Type A (Botox) for the Treatment of Cervical Dystonia and Upper Thoracic Muscular Pain Botulinum Toxin Type A - Refractory Cervicothoracic Myofascial Pain Syndrome (CMPS), Cervical Dystonia | Phase 1 / Phase 2 | Completed | Vanderbilt University | 20 | 2004-03-01 | 2016-06-01 |
| Study of Air Stream in Voice Production airway interruption test - Spastic Dysphonia, Healthy | Phase 1 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 30 | 2001-05-01 | 2008-03-04 |
Torticollis (5) · Dystonic Disorders (2) · Blepharospasm (1) · Cerebral Palsy (1) · Dysphonia (1) · Essential Tremor (1) · Movement Disorders (1) · Multiple Sclerosis (1) · Muscle Hypertonia (1) · Muscle Spasticity (1) · Neuralgia (1) · Parkinson Disease (1) · Spastic Paraplegia, Hereditary (1) · Spinal Cord Injuries (1)
Dyskinesias (11) · Neurologic Manifestations (11) · Pathological Conditions, Signs and Symptoms (11) · Signs and Symptoms (11) · Nervous System Diseases (6) · Central Nervous System Diseases (4) · Brain Diseases (2) · Movement Disorders (2) · Neurodegenerative Diseases (2) · Neuromuscular Diseases (2) · Peripheral Nervous System Diseases (2) · Autoimmune Diseases (1) · Autoimmune Diseases of the Nervous System (1) · Basal Ganglia Diseases (1)
Botulinum Toxins, Type A (2) · Ampicillin (1) · Electrodes (1) · Occupational Therapy (1) · Sugars (1) · perampanel (1)
National Institute of Neurological Disorders and Stroke (NINDS) (4) · Hugel (1) · Mentor Worldwide, LLC (1) · Motric Bio (1) · University Children's Hospital, Zurich (1) · University Health Network, Toronto (1) · University of Florida (1) · Vanderbilt University (1)
United States (9) · Canada (1) · South Korea (1) · Switzerland (1)
Alan Hand, MD (1) · Carolyn Austin (1) · Irene Malaty, M.D. (1) · Mark Hallett, M.D. (1) · Susan H Fox, MRCP(UK), PhD (1) · Thomas L Davis, MD (1)