34 terminated. 34 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 34 | Terminated 34 |
Follow Dyssomnias: new trials by email Literature Review of Dyssomnias trials Research Report on Dyssomnias
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Double-blind Randomized Controlled Trial Comparing Suvorexant 20 mg to Placebo for Treatment of Insomnia in Cancer Survivors Suvorexant Tablets, Placebo Control - Breast Cancer, Insomnia | Phase 4 | Terminated | Medical University of South Carolina | 6 | 2024-09-20 | 2026-08-12 |
| CBT-I Augmentation of Medication for Drinking in AUD Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene Education - Alcohol Use Disorder With Insomnia | Phase 4 | Terminated | VA Office of Research and Development | 82 | 2022-06-15 | 2025-02-28 |
| Insomnia Prevalence and Treatment Impact on Systemic Hypertension Ramelteon (RozeremR), sleep hygiene - Insomnia, Hypertension | Phase 4 | Terminated | University of Sao Paulo | 5 | 2022-05-01 | 2022-12-29 |
| Clinical Trial of Solriamfetol for Excessive Sleepiness Related to Shift Work Disorder Solriamfetol Oral Tablet, Placebo - Excessive Sleepiness, Shift-work Disorder | Phase 4 | Terminated | Charles A. Czeisler, PhD, MD | 84 | 2021-07-21 | 2025-09-24 |
| Oral Iron Frequency for Childhood Restless Leg Syndrome/Periodic Limb Movement Disorder Ferrous sulfate - Sleep Disorder, Restless Legs Syndrome | Phase 4 | Terminated | Mayo Clinic | 6 | 2020-11-16 | 2024-05-22 |
| Pramipexole for Restless Leg Syndrome in Peritoneal Dialysis Patients Pramipexole, placebo - Restless Legs Syndrome | Phase 4 | Terminated | Dong Jie | 21 | 2019-07-01 | 2021-12-09 |
| Obstructive Sleep Apnea Treatment on Cardiovascular Events in Patients With Acute Cardiogenic Pulmonary Edema: CPAP-CARE STUDY. CPAP, Nasal Strips - Obstructive Sleep Apnea, Pulmonary Edema Cardiac Cause | Phase 4 | Terminated | University of Sao Paulo | 150 | 2019-04-01 | 2024-06-07 |
| A Six Week, Randomized, Double-Blind Placebo-Controlled, Suvorexant Augmentation Study of Antidepressant Treatment of Major Depressive Disorder With Residual Insomnia suvorexant, Placebo - Depression, Major Depressive Disorder | Phase 4 | Terminated | Institute for Advanced Medical Research, Alpharetta, GA | 32 | 2017-03-01 | 2026-11-04 |
| Benefit of One Month Zopiclone Intake on Adaptative Servoventilation Compliance Zopiclone, Placebo - Sleep Apnea, Central, Ventricular Dysfunction | Phase 4 | Terminated | University Hospital, Grenoble | 2 | 2016-05-01 | 2021-05-26 |
| Suvorexant in Insomnia Co-morbid With Fibromyalgia suvorexant, placebo - Insomnia, Fibromyalgia | Phase 4 | Terminated | Henry Ford Health System | 10 | 2016-02-01 | 2021-06-16 |
| Evaluation of Modafinil vs Placebo for Treatment of Anesthesia Delayed Emergence in Obstructive Sleep Apnea Modafinil, Placebo - Obstructive Sleep Apnea, Delayed Emergence From Anesthesia | Phase 4 | Terminated | Milton S. Hershey Medical Center | 105 | 2016-02-01 | 2019-06-20 |
| Ketamine and Propofol Combination Versus Propofol for Upper Gastrointestinal Endoscopy Ketofol, Propofol, Saline - Obesity, Bariatrics | Phase 4 | Terminated | Icahn School of Medicine at Mount Sinai | 22 | 2016-01-01 | 2020-02-11 |
| Inspire® Upper Airway Stimulation System Inspire® Upper Airway Stimulation (UAS) System - Obstructive Sleep Apnea | Phase 4 | Terminated | Inspire Medical Systems, Inc. | 16 | 2015-08-01 | 2016-08-11 |
| The Effect of Dexmedetomidine on Airway Complications After Deep or Awake Extubation Normal Saline, Dexmedetomidine - Adenotonsillar Hypertrophy, Obstructive Sleep Apnea | Phase 4 | Terminated | Massachusetts Eye and Ear Infirmary | 92 | 2015-03-01 | 2020-04-09 |
| Post-operative Pain Control After Pediatric Adenotonsillectomy Ibuprofen, Hydrocodone-Acetaminophen - Recurrent Tonsillitis, Obstructive Sleep Apnea | Phase 4 | Terminated | Emory University | 45 | 2014-11-01 | 2018-04-25 |
| Blinded, Randomized Study of Gabapentin (Neurontin®) and Gabapentin Enacarbil (Horizant™) in Restless Leg Syndrome Gabapentin immediate release, Gabapentin enacarbil extended release - Restless Leg Syndrome | Phase 4 | Terminated | Theresa Zesiewicz, MD | 5 | 2014-04-01 | 2021-11-16 |
| Intermittent Hypoxia 2: Cardiovascular and Metabolism Placebo, Valsartan, Amlodipine - Hypoxia, Sleep Apnea | Phase 4 | Terminated | University Hospital, Grenoble | 12 | 2013-08-07 | 2018-12-31 |
| Varenicline Treatment for Excessive Daytime Sleepiness in Parkinson's Disease Varenicline, Placebo (for varenicline) - Parkinson's Disease | Phase 4 | Terminated | Amsterdam UMC, location VUmc | 22 | 2013-05-01 | 2018-10-09 |
| Inhaled Fluticasone Effects on Upper Airway Patency in Obstructive Lung Disease Inhaled Fluticasone Propionate - Asthma, Chronic Obstructive Pulmonary Disease | Phase 4 | Terminated | VA Office of Research and Development | 25 | 2013-03-12 | 2020-02-05 |
| Magnesium Oxide Monohydrate for Nocturnal Leg Cramps MAGNOX 520®, placebo - Nocturnal Leg Cramps, Quality of Life | Phase 4 | Terminated | Uzi Milman | 94 | 2013-02-01 | 2017-07-21 |
Showing 20 of 34. Sign in to see all of them.
Sleep Apnea, Obstructive (14) · Sleep Initiation and Maintenance Disorders (13) · Restless Legs Syndrome (3) · Sleep Apnea Syndromes (3) · Agnosia (2) · Disorders of Excessive Somnolence (2) · Fatigue (2) · Sleep Wake Disorders (2) · Tonsillitis (2) · Alcoholism (1) · Alzheimer Disease (1) · Anemia, Iron-Deficiency (1) · Anxiety Disorders (1) · Asthma (1) · Attention Deficit Disorder with Hyperactivity (1)
Nervous System Diseases (34) · Sleep Disorders, Intrinsic (34) · Sleep Wake Disorders (32) · Mental Disorders (17) · Apnea (16) · Respiration Disorders (16) · Respiratory Tract Diseases (16) · Sleep Apnea Syndromes (13) · Pathological Conditions, Signs and Symptoms (11) · Signs and Symptoms (9) · Neurologic Manifestations (5) · Cardiovascular Diseases (4) · Chemically-Induced Disorders (4) · Parasomnias (4)
suvorexant (3) · Eszopiclone (2) · Modafinil (2) · Sodium Chloride (2) · ramelteon (2) · Amlodipine (1) · Amoxicillin (1) · Bupropion (1) · Clavulanic Acid (1) · Cognitive Behavioral Therapy (1) · Continuous Positive Airway Pressure (1) · Dexmedetomidine (1) · Dopamine Agonists (1) · Drug Delivery Systems (1) · Estrogens (1)
University of Chicago (3) · University of Sao Paulo (3) · University Hospital, Grenoble (2) · University of California, San Diego (2) · VA Office of Research and Development (2) · Accelerated Community Oncology Research Network (1) · Amsterdam UMC, location VUmc (1) · Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal (1) · Charles A. Czeisler, PhD, MD (1) · Children's Specialized Hospital (1) · Dong Jie (1) · Emory University (1) · Henry Ford Health System (1) · Icahn School of Medicine at Mount Sinai (1) · Inspire Medical Systems, Inc. (1)
United States (24) · Brazil (3) · France (2) · Belgium (1) · Canada (1) · China (1) · Germany (1) · Israel (1) · Netherlands (1)
Albert J Arias, MD, MS (1) · Andrea H. Weinberger, Ph.D. (1) · Andrew Goldberg, MD (1) · Angelo Sambunaris, MD (1) · Armin Steffen, PD Dr. med. (1) · Bernard Uitdehaag, Phd, MD (1) · Cara Tannenbaum, MD (1) · Charles A Czeisler, PhD,MD (1) · Clemens Heiser, Dr. med. (1) · Daniel J Katz, MD (1) · David A Ehrmann, M.D. (1) · David A Maerz, MD (1) · David M Rapoport, MD (1) · Edward J. Stepanski, Ph.D. (1) · Elisabeth Foncke, PhD, MD (1)
PMID 15683149, PMID 18172212, PMID 18647805, PMID 21123449, PMID 23019248, PMID 23514019, PMID 24733354, PMID 28143413, PMID 28241153, PMID 28473524, PMID 31992394, PMID 32075834, PMID 33189083, PMID 33275278, PMID 41590992
I01CX001957 (1), R01HL075079 (1)